sulfaphenazole has been researched along with Hypertension in 4 studies
Sulfaphenazole: A sulfonilamide anti-infective agent.
sulfaphenazole : A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We aimed to assess the effect of sulfaphenazole, a specific CYP 2C9 inhibitor, on tPA release in normotensive subjects and patients with essential hypertension." | 3.75 | Effect of sulfaphenazole on tissue plasminogen activator release in normotensive subjects and hypertensive patients. ( De Negri, F; Duranti, E; Giannarelli, C; Magagna, A; Salvetti, A; Taddei, S; Virdis, A, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giannarelli, C | 1 |
| Virdis, A | 2 |
| De Negri, F | 1 |
| Magagna, A | 2 |
| Duranti, E | 1 |
| Salvetti, A | 2 |
| Taddei, S | 2 |
| Brown, NJ | 1 |
| Pretorius, M | 1 |
| Büssemaker, E | 1 |
| Popp, R | 1 |
| Fisslthaler, B | 1 |
| Larson, CM | 1 |
| Fleming, I | 1 |
| Busse, R | 1 |
| Brandes, RP | 1 |
| Versari, D | 1 |
| Cipriano, A | 1 |
| Ghiadoni, L | 1 |
| Galetta, F | 1 |
| Franzoni, F | 1 |
4 other studies available for sulfaphenazole and Hypertension
| Article | Year |
|---|---|
Effect of sulfaphenazole on tissue plasminogen activator release in normotensive subjects and hypertensive patients.
Topics: Acetylcholine; Adult; Aryl Hydrocarbon Hydroxylases; Blood Pressure; Bradykinin; Case-Control Studie | 2009 |
Letter by Brown and Pretorius regarding article, "effect of sulfaphenazole on tissue plasminogen activator release in normotensive subjects and hypertensive patients".
Topics: Endothelium, Vascular; Humans; Hypertension; Sulfaphenazole; Tissue Plasminogen Activator | 2009 |
Aged spontaneously hypertensive rats exhibit a selective loss of EDHF-mediated relaxation in the renal artery.
Topics: Acetylcholine; Age Factors; Animals; Biological Factors; Cytochrome P-450 Enzyme Inhibitors; Enzyme | 2003 |
Identification of a cytochrome P450 2C9-derived endothelium-derived hyperpolarizing factor in essential hypertensive patients.
Topics: Acetylcholine; Adult; Aryl Hydrocarbon Hydroxylases; Ascorbic Acid; Biological Factors; Bradykinin; | 2006 |