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ethylmaleimide and Hypertension

ethylmaleimide has been researched along with Hypertension in 11 studies

Ethylmaleimide: A sulfhydryl reagent that is widely used in experimental biochemical studies.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"There is probably a heterogeneous etiology for essential hypertension (EHT), and abnormal erythrocyte sodium-lithium countertransport (Na/Li CT) is common in a subgroup of patients with a strong family history of hypertension and cardiovascular disease (EHT-FH patients)."9.09Thiol protein defect in sodium-lithium countertransport in subset of essential hypertension. ( Mead, P; Thomas, TH; Wilkinson, R, 1999)
"There is probably a heterogeneous etiology for essential hypertension (EHT), and abnormal erythrocyte sodium-lithium countertransport (Na/Li CT) is common in a subgroup of patients with a strong family history of hypertension and cardiovascular disease (EHT-FH patients)."5.09Thiol protein defect in sodium-lithium countertransport in subset of essential hypertension. ( Mead, P; Thomas, TH; Wilkinson, R, 1999)
"Indomethacin treatment did not affect the mastoparan contraction even though mastoparan has been shown to stimulate phospholipase A2 in other cell types."1.29Enhanced vascular reactivity to mastoparan, a G protein activator, in genetically hypertensive rats. ( Kanagy, NL; Webb, RC, 1994)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's6 (54.55)18.2507
2000's2 (18.18)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mead, PA1
Harvey, JN1
Rutherford, PA3
Leitch, H1
Thomas, TH5
Boomsma, F1
de Bruyn, JH1
Derkx, FH1
Schalekamp, MA1
Levy, R1
Livne, A1
West, IC3
Wilkinson, R4
Kanagy, NL1
Webb, RC1
Sela, S2
Sidhu, A2
White, BH1
Uh, M1
Kimura, K1
Patel, S1
Vareesangthip, K1
Mead, P1
Watkins, SL1
Lauf, PK1
Perkins, CM1
Adragna, NC1

Trials

1 trial available for ethylmaleimide and Hypertension

ArticleYear
Thiol protein defect in sodium-lithium countertransport in subset of essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:6

    Topics: Antihypertensive Agents; Antiporters; Cholesterol; Enzyme Activation; Erythrocytes; Ethylmaleimide;

1999

Other Studies

10 other studies available for ethylmaleimide and Hypertension

ArticleYear
Sodium-lithium countertransport and the Gly460-->Trp alpha-adducin polymorphism in essential hypertension.
    Clinical science (London, England : 1979), 2005, Volume: 108, Issue:3

    Topics: Adult; Analysis of Variance; Antiporters; Calmodulin-Binding Proteins; Case-Control Studies; Chi-Squ

2005
Opposite effects of captopril on angiotensin I-converting enzyme 'activity' and 'concentration'; relation between enzyme inhibition and long-term blood pressure response.
    Clinical science (London, England : 1979), 1981, Volume: 60, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Drug Storage; Ethylmaleimide; H

1981
The erythrocyte membrane in essential hypertension. Characterization of the temperature dependence of lithium efflux.
    Biochimica et biophysica acta, 1984, Jan-11, Volume: 769, Issue:1

    Topics: Biological Transport; Cell Membrane Permeability; Erythrocyte Membrane; Ethylmaleimide; Humans; Hype

1984
Sulphydryl group control of sodium-lithium countertransport kinetics: a membrane protein control abnormality in essential hypertension.
    European journal of clinical investigation, 1995, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Antiporters; Erythrocytes; Ethylmaleimide; Humans; Hypertension; Kinetics; Lithiu

1995
Enhanced vascular reactivity to mastoparan, a G protein activator, in genetically hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:6 Pt 2

    Topics: Animals; Blood Vessels; Ethylmaleimide; GTP-Binding Proteins; Hypertension; In Vitro Techniques; Ind

1994
Sulfhydryl groups of renal D1A dopamine receptors: differential sensitivity of receptors to N-ethylmaleimide in normotensive and hypertensive rats.
    Journal of hypertension, 1996, Volume: 14, Issue:5

    Topics: Animals; Binding Sites; Dose-Response Relationship, Drug; Ethylmaleimide; Free Radicals; Hypertensio

1996
Dysfunctional D1A receptor-G-protein coupling in proximal tubules of spontaneously hypertensive rats is not due to abnormal G-proteins.
    Journal of hypertension, 1997, Volume: 15, Issue:3

    Topics: Alkylating Agents; Animals; Binding Sites; Binding, Competitive; Ethylmaleimide; GTP-Binding Protein

1997
Erythrocyte membrane thiol proteins associated with changes in the kinetics of Na/Li countertransport: a possible molecular explanation of changes in disease.
    European journal of clinical investigation, 1998, Volume: 28, Issue:4

    Topics: Adult; Alkylation; Animals; Antiporters; Biotin; Diabetic Nephropathies; Electrophoresis, Polyacryla

1998
Abnormal thiol reactivity of tropomyosin in essential hypertension and its association with abnormal sodium-lithium countertransport kinetics.
    Journal of hypertension, 2001, Volume: 19, Issue:3

    Topics: Biotin; Case-Control Studies; Erythrocytes; Ethylmaleimide; Female; Humans; Hypertension; Ion Transp

2001
Cell volume and metabolic dependence of NEM-activated K+-Cl- flux in human red blood cells.
    The American journal of physiology, 1985, Volume: 249, Issue:1 Pt 1

    Topics: Adenosine Triphosphate; Biological Transport; Chlorides; Erythrocyte Volume; Erythrocytes; Ethylmale

1985