efonidipine has been researched along with Hypertension in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (24.14) | 18.2507 |
| 2000's | 14 (48.28) | 29.6817 |
| 2010's | 8 (27.59) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ball, CJ; Beltrame, JF; Saint, DA; Turner, SP; Wilson, DP | 1 |
| Fujii, M; Horie, M; Kawahara, C; Nishiyama, K; Tanaka, T; Tsutamoto, T; Yamaji, M; Yamamoto, T | 1 |
| Ban, N; Endo, K; Kawana, H; Miyashita, Y; Nagayama, D; Ohhira, M; Oyama, T; Saiki, A; Sasaki, H; Shirai, K; Yamaguchi, T | 1 |
| Jin, D; Miyazaki, M; Sakonjo, H; Takai, S | 1 |
| Goto, Y; Ishii, M; Ogihara, T; Rakugi, H | 1 |
| Okura, T | 1 |
| Goto, Y; Hayashi, K; Ishii, M; Saruta, T | 1 |
| Ito, S | 1 |
| Goto, Y; Ishii, M; Kawano, Y; Ogihara, T; Saruta, T | 1 |
| Ninomiya, T | 1 |
| Fujita, M; Ikai, A; Mitani, S; Miyamoto, S; Ogura, C; Ono, K; Sugimoto, N; Tanaka, S | 1 |
| Fukuhara, S; Kanazawa, S; Nomura, S | 1 |
| Harada, K; Ito, S; Nakaya, Y; Nishikado, A; Nomura, M; Uehara, K | 1 |
| Hayashi, K; Kumagai, H; Saruta, T | 1 |
| Hasegawa, K; Hayashi, K; Homma, K; Kanda, T; Sugano, N; Takamatsu, I; Tatematsu, S; Wakino, S; Yoshioka, K | 1 |
| Higashi, Y; Ishida, M; Ishida, T; Kambe, M; Miho, N; Oshima, T; Ozono, R; Teragawa, H; Yano, Y; Yoshizumi, M | 1 |
| Goto, Y; Ishii, M | 1 |
| Ahn, JY; Chung, WJ; Han, SH; Kim, JA; Koh, KK; Lee, SJ; Lee, Y; Quon, MJ; Shin, EK | 1 |
| Fujii, M; Horie, M; Sakai, H; Tanaka, T; Tsutamoto, T; Yamamoto, T | 1 |
| Hara, Y; Hasegawa, K; Hayashi, K; Homma, K; Hosoya, T; Kanda, T; Saruta, T; Suetsugu, Y; Sugano, N; Tatematsu, S; Tokudome, G; Utsunomiya, Y; Wakino, S; Yoshioka, K; Yoshizawa, T | 1 |
| Furukawa, S; Hayashi, K; Hirata, H; Masuda, Y; Shudo, C; Sugita, H; Tanaka, S; Tomita, K | 1 |
| Furukawa, S; Hayashi, K; Hirata, H; Masuda, Y; Shudo, C; Tamura, T; Yamamoto, O | 1 |
| Kasuya, Y; Masuda, Y; Sakai, T; Shigenobu, K; Shudo, C; Tanaka, S | 1 |
| Furukawa, S; Hayashi, K; Hirata, H; Masuda, Y; Shikada, K; Shudo, C; Sugita, H; Tamura, T; Tanaka, S; Tomita, K | 1 |
| Shou, I; Takeda, M; Tomino, Y | 1 |
| Fujiwara, K; Hayashi, K; Kanno, Y; Saruta, T; Takenaka, T | 1 |
| Hoshino, T; Kaburagi, T; Mori, N; Sakata, K; Yokoyama, S; Yoshida, H | 1 |
1 review(s) available for efonidipine and Hypertension
| Article | Year |
|---|---|
[JATOS].
Topics: Aged; Aged, 80 and over; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Japan; Male; Nitrophenols; Organophosphorus Compounds; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Single-Blind Method | 2006 |
12 trial(s) available for efonidipine and Hypertension
| Article | Year |
|---|---|
Principal results of the Japanese trial to assess optimal systolic blood pressure in elderly hypertensive patients (JATOS).
Topics: Aged; Aged, 80 and over; Aging; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Dihydropyridines; Diuretics; Dose-Response Relationship, Drug; Endpoint Determination; Female; Humans; Hypertension; Japan; Male; Nitrophenols; Organophosphorus Compounds; Single-Blind Method; Systole | 2008 |
Long-term effect of efonidipine therapy on plasma aldosterone and left ventricular mass index in patients with essential hypertension.
Topics: Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Natriuretic Peptide, Brain; Nitrophenols; Organophosphorus Compounds; Renin; Time Factors | 2009 |
Protective effects of efonidipine, a T- and L-type calcium channel blocker, on renal function and arterial stiffness in type 2 diabetic patients with hypertension and nephropathy.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Aldosterone; Amlodipine; Arteries; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Deoxyguanosine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dihydropyridines; Female; Glycated Hemoglobin; Humans; Hypertension; Kidney; Lipids; Male; Middle Aged; Nitrophenols; Organophosphorus Compounds | 2009 |
Impact of renal function on cardiovascular events in elderly hypertensive patients treated with efonidipine.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Cardiovascular Diseases; Chronic Disease; Dihydropyridines; Female; Humans; Hypertension; Kidney; Kidney Diseases; Male; Nitrophenols; Organophosphorus Compounds; Prospective Studies | 2010 |
Association of blood pressure control and metabolic syndrome with cardiovascular risk in elderly Japanese: JATOS study.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Asian People; Blood Pressure; Cardiovascular Diseases; Dihydropyridines; Female; Humans; Hypertension; Japan; Male; Metabolic Syndrome; Nitrophenols; Organophosphorus Compounds; Prevalence; Risk Factors | 2011 |
L/T-type and L/N-type calcium-channel blockers attenuate cardiac sympathetic nerve activity in patients with hypertension.
Topics: Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cross-Over Studies; Dihydropyridines; Female; Heart; Heart Conduction System; Hemodynamics; Humans; Hypertension; Male; Nitrophenols; Norepinephrine; Organophosphorus Compounds; Prospective Studies; Sympathetic Nervous System | 2012 |
Effects of efonidipine on platelet and monocyte activation markers in hypertensive patients with and without type 2 diabetes mellitus.
Topics: Aged; Antihypertensive Agents; Blood Cell Count; Cell Adhesion Molecules; Diabetes Mellitus, Type 2; Dihydropyridines; Female; Humans; Hypertension; Male; Middle Aged; Monocytes; Nitrophenols; Organophosphorus Compounds; Platelet Activation; Vascular Diseases | 2002 |
Effect of efonidipine and ACE inhibitors on proteinuria in human hypertension with renal impairment.
Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; Nitrophenols; Organophosphorus Compounds; Proteinuria | 2003 |
The Japanese Trial to Assess Optimal Systolic Blood Pressure in Elderly Hypertensive Patients (JATOS): protocol, patient characteristics, and blood pressure during the first 12 months.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Dihydropyridines; Female; Humans; Hypertension; Japan; Male; Nitrophenols; Organophosphorus Compounds; Prospective Studies; Treatment Outcome | 2005 |
Beneficial effect of T-type calcium channel blockers on endothelial function in patients with essential hypertension.
Topics: Adult; Aged; Blood Flow Velocity; Brachial Artery; Calcium Channel Blockers; Case-Control Studies; Dihydropyridines; Endothelial Cells; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrophenols; Organophosphorus Compounds; Vasodilation | 2005 |
Efonidipine simultaneously improves blood pressure, endothelial function, and metabolic parameters in nondiabetic patients with hypertension.
Topics: Adiponectin; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cholesterol, HDL; Dihydropyridines; Endothelium, Vascular; Humans; Hypertension; Leptin; Nitrophenols; Organophosphorus Compounds; Placebos; Vasodilation | 2007 |
Comparison of the effects of efonidipine and amlodipine on aldosterone in patients with hypertension.
Topics: Aged; Aged, 80 and over; Aldosterone; Amlodipine; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Natriuretic Peptide, Brain; Nitrophenols; Norepinephrine; Organophosphorus Compounds | 2007 |
16 other study(ies) available for efonidipine and Hypertension
| Article | Year |
|---|---|
Heterogeneity of L- and T-channels in the vasculature: rationale for the efficacy of combined L- and T-blockade.
Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydropyridines; Humans; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Mibefradil; Microvessels; Nifedipine; Nitrophenols; Organophosphorus Compounds; Potassium Chloride; Rats; Rats, Sprague-Dawley; Subcutaneous Fat; Vasoconstriction; Verapamil | 2009 |
Combination therapy with irbesartan and efonidipine for attenuation of proteinuria in Dahl salt-sensitive rats.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Chemokine CCL2; Collagen Type I; Dihydropyridines; Drug Therapy, Combination; Gene Expression; Glomerulosclerosis, Focal Segmental; Hypertension; Irbesartan; Kidney Glomerulus; Male; NADPH Oxidases; Nitrophenols; Organophosphorus Compounds; Proteinuria; Rats; Rats, Inbred Dahl; Tetrazoles; Transforming Growth Factor beta | 2010 |
Comparison of strict- and mild-blood pressure control in elderly hypertensive patients: a per-protocol analysis of JATOS.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Dihydropyridines; Female; Humans; Hypertension; Incidence; Japan; Male; Nitrophenols; Organophosphorus Compounds; Randomized Controlled Trials as Topic; Treatment Outcome | 2010 |
Efonidipine improves renal function and decreases proteinuria in elderly hypertensive patients in the JATOS study.
Topics: Aged; Antihypertensive Agents; Chronic Disease; Dihydropyridines; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Kidney Diseases; Nitrophenols; Organophosphorus Compounds; Proteinuria; Randomized Controlled Trials as Topic | 2010 |
Is renal antiaging possible?
Topics: Aging; Antihypertensive Agents; Chronic Disease; Dihydropyridines; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Kidney Diseases; Nitrophenols; Organophosphorus Compounds; Randomized Controlled Trials as Topic | 2010 |
Is metabolic syndrome a risk factor for cardiovascular disease in late elderly?
Topics: Blood Pressure; Cardiovascular Diseases; Dihydropyridines; Female; Humans; Hypertension; Male; Metabolic Syndrome; Nitrophenols; Organophosphorus Compounds | 2011 |
Clinical efficacy of efonidipine hydrochloride, a T-type calcium channel inhibitor, on sympathetic activities.
Topics: 3-Iodobenzylguanidine; Adult; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Electrocardiography; Female; Heart; Heart Rate; Hemodynamics; Humans; Hypertension; Iodine Radioisotopes; Male; Nitrophenols; Organophosphorus Compounds; Radionuclide Imaging; Spectrum Analysis; Sympathetic Nervous System; Tachycardia; Treatment Outcome | 2003 |
Divergent action of calcium channel blockers on ATP-binding cassette protein expression.
Topics: Atherosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dihydropyridines; Humans; Hypertension; Janus Kinase 2; Nitrophenols; Organophosphorus Compounds; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; RNA, Messenger | 2005 |
T-type calcium channel blockade as a therapeutic strategy against renal injury in rats with subtotal nephrectomy.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Chronic Disease; Dihydropyridines; Hypertension; Kidney Diseases; Male; Nephrectomy; Nitrophenols; Organophosphorus Compounds; Rats; Rats, Inbred SHR | 2008 |
Renal protective effect of efonidipine hydrochloride (NZ-105), a new calcium antagonist, in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Calcium Channel Blockers; Dihydropyridines; Hypertension; Kidney; Male; Nitrophenols; Organ Size; Organophosphorus Compounds; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1994 |
Influence of efonidipine hydrochloride, calcium antagonist on the epithelium of prostates in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Epithelium; Hypertension; Male; Nitrophenols; Organophosphorus Compounds; Prostate; Rats; Rats, Inbred SHR | 1994 |
Effects of long-term oral administration of NZ-105, a novel calcium antagonist, with or without propranolol in spontaneously hypertensive rats.
Topics: Administration, Oral; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Heart; Heart Rate; Hypertension; Kidney; Liver; Male; Nitrophenols; Organ Size; Organophosphorus Compounds; Propranolol; Rats; Rats, Inbred SHR; Renin; Time Factors | 1993 |
Effects of efonidipine, nicardipine and captopril on proteinuria in aged spontaneously hypertensive rats.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium Channel Blockers; Captopril; Creatinine; Dihydropyridines; Heart Rate; Hypertension; Kidney; Male; Nicardipine; Nitrophenols; Organophosphorus Compounds; Proteinuria; Rats; Rats, Inbred SHR | 1996 |
Effects of the antihypertensive drug efonidipine hydrochloride on albuminuria and renal histopathology in young spontaneously hypertensive rats with diabetes.
Topics: Albuminuria; Animals; Antihypertensive Agents; Diabetes Mellitus, Experimental; Dihydropyridines; Hypertension; Kidney; Male; Nitrophenols; Organophosphorus Compounds; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Streptozocin | 1998 |
Renal protective effects of efonidipine in partially nephrectomized spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Disease Progression; Hypertension; Kidney; Male; Nephrectomy; Nitrophenols; Organophosphorus Compounds; Proteinuria; Rats; Rats, Inbred SHR; Systole | 1998 |
[Antihypertensive effects and pharmacokinetics of NZ-105 single administration in patients with hypertension].
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Dihydropyridines; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Nitrophenols; Organophosphorus Compounds | 1992 |