pyridoxal phosphate has been researched along with Hypertension in 10 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Adult male Sprague-Dawley rats placed on a pyridoxine-deficient diet for 8 weeks showed significant hypertension compared with pyridoxine-supplemented controls." | 7.67 | Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988) |
| "Our study confirmed, in a population-based setting, the importance of the known determinants of fasting tHcy and suggested that other dietary and lifestyle factors, including vitamin B-6, riboflavin, alcohol, and caffeine intakes as well as smoking and hypertension, influence circulating tHcy concentrations." | 3.71 | Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort. ( Bostom, AG; Jacques, PF; Rich, S; Rosenberg, IH; Selhub, J; Wilson, PW, 2001) |
| " Adult male Sprague-Dawley rats placed on a pyridoxine-deficient diet for 8 weeks showed significant hypertension compared with pyridoxine-supplemented controls." | 3.67 | Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988) |
| "Pyridoxal phosphate has a role in regulating cellular calcium transport through both the voltage-mediated and ATP-mediated purinergic mechanisms of cellular calcium influx and, hence, has a role in the control of hypertension." | 2.52 | Antihypertensive and neuroprotective actions of pyridoxine and its derivatives. ( Dakshinamurti, K; Dakshinamurti, S, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Greaney, JL | 1 |
| Matthews, EL | 1 |
| Boggs, ME | 1 |
| Edwards, DG | 1 |
| Duncan, RL | 1 |
| Farquhar, WB | 1 |
| Dakshinamurti, S | 1 |
| Dakshinamurti, K | 2 |
| Lin, PT | 1 |
| Cheng, CH | 1 |
| Wei, JC | 1 |
| Huang, YC | 1 |
| Gur, S | 1 |
| Sikka, SC | 1 |
| Knight, GE | 1 |
| Burnstock, G | 1 |
| Hellstrom, WJ | 1 |
| Pérez-Rivera, AA | 1 |
| Fink, GD | 1 |
| Galligan, JJ | 1 |
| Graciano, ML | 1 |
| Nishiyama, A | 1 |
| Jackson, K | 1 |
| Seth, DM | 1 |
| Ortiz, RM | 1 |
| Prieto-Carrasquero, MC | 1 |
| Kobori, H | 1 |
| Navar, LG | 1 |
| Jacques, PF | 1 |
| Bostom, AG | 1 |
| Wilson, PW | 1 |
| Rich, S | 1 |
| Rosenberg, IH | 1 |
| Selhub, J | 1 |
| Brophy, MH | 1 |
| Siiteri, PK | 1 |
| Paulose, CS | 1 |
| Packer, S | 1 |
| Stephens, NL | 1 |
| Boomsma, F | 1 |
| van der Hoorn, FA | 1 |
| Schalekamp, MA | 1 |
1 review available for pyridoxal phosphate and Hypertension
| Article | Year |
|---|---|
Antihypertensive and neuroprotective actions of pyridoxine and its derivatives.
Topics: Animals; Antihypertensive Agents; Humans; Hypertension; Neuroprotective Agents; Pyridoxal Phosphate; | 2015 |
1 trial available for pyridoxal phosphate and Hypertension
| Article | Year |
|---|---|
Exaggerated exercise pressor reflex in adults with moderately elevated systolic blood pressure: role of purinergic receptors.
Topics: Aged; Animals; Blood Pressure; Calcium; Exercise; Female; Ganglia, Spinal; Hand Strength; Humans; Hy | 2014 |
8 other studies available for pyridoxal phosphate and Hypertension
| Article | Year |
|---|---|
Low plasma pyridoxal 5'-phosphate concentration and MTHFR 677C-->T genotypes are associated with increased risk of hypertension.
Topics: Alleles; Blood Pressure; Chromatography, High Pressure Liquid; Female; Folic Acid; Genotype; Humans; | 2008 |
Purinergic contraction of the rat vas deferens in L-NAME-induced hypertension: effect of sildenafil.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Enzyme Inhibitors; Hypertension; Male; Muscle | 2010 |
Alpha-1B adrenoceptors mediate neurogenic constriction in mesenteric arteries of normotensive and DOCA-salt hypertensive mice.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; D | 2005 |
Purinergic receptors contribute to early mesangial cell transformation and renal vessel hypertrophy during angiotensin II-induced hypertension.
Topics: Actins; Adenosine Triphosphate; Angiotensin II; Animals; Arterioles; Blood Pressure; Cell Proliferat | 2008 |
Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Caffeine; Cohort Studies; Creatinine; | 2001 |
Pyridoxal phosphate and hypertensive disorders of pregnancy.
Topics: Administration, Oral; Brain; Female; Fetus; Growth; Humans; Hypertension; Infant, Newborn; Injection | 1975 |
Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat.
Topics: Animals; Blood Pressure; Dopamine; gamma-Aminobutyric Acid; Hypertension; Hypothalamus; Male; Norepi | 1988 |
Determination of aromatic-L-amino acid decarboxylase in human plasma.
Topics: Adrenal Gland Neoplasms; Aromatic-L-Amino-Acid Decarboxylases; Chromatography, High Pressure Liquid; | 1986 |