5-(n,n-hexamethylene)amiloride has been researched along with Hypertension in 3 studies
5-(N,N-hexamethylene)amiloride: inhibitor of Na+-H+ exchange; has anti-HIV-1 activity
5-(N,N-hexamethylene)amiloride : A member of the class of pyrazines that is amiloride in which the two amino hydrogens at position N-5 are replaced by a hexamethylene moiety, resulting in the formation of an azepane ring.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, YF | 1 |
| Yang, RH | 1 |
| Meng, QC | 1 |
| Cragoe, EJ | 1 |
| Oparil, S | 1 |
| Schussheim, AE | 1 |
| Radda, GK | 1 |
| Kuriyama, S | 1 |
| Nakamura, K | 1 |
| Horiguchi, M | 1 |
| Uchida, H | 1 |
| Sakai, O | 1 |
3 other studies available for 5-(n,n-hexamethylene)amiloride and Hypertension
| Article | Year |
|---|---|
Sodium-proton (Na+/H+) exchange inhibition increases blood pressure in spontaneously hypertensive rat.
Topics: Amiloride; Animals; Blood Pressure; Hypertension; Kinetics; Male; Norepinephrine; Rats; Rats, Inbred | 1994 |
Altered Na(+)- H(+)- exchange activity in the spontaneously hypertensive perfused rat heart.
Topics: Acidosis; Amiloride; Animals; Carbon Dioxide; Heart; Hydrogen-Ion Concentration; Hypertension; In Vi | 1995 |
Decreased insulin-sensitive Ca2+ transport in cultured vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Biological Transport; Calcium; Ca | 1992 |