Page last updated: 2024-11-08

dimethylphenylpiperazinium iodide and Hypertension

dimethylphenylpiperazinium iodide has been researched along with Hypertension in 5 studies

Dimethylphenylpiperazinium Iodide: A selective nicotinic cholinergic agonist used as a research tool. DMPP activates nicotinic receptors in autonomic ganglia but has little effect at the neuromuscular junction.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
" Dose-response curves were plotted with 1n-dose on the x-axis and percent of maximum change in TPR on the y-axis, and the following indices of responsiveness were used: slope, 1nED50, 1nx-intercept, and maximum response."1.27Increased systemic vascular responsiveness to catecholamines in spontaneously hypertensive rats. ( Walsh, GM, 1983)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moura, E1
Pinto, CE1
Caló, A1
Serrão, MP1
Afonso, J1
Vieira-Coelho, MA1
CHEN, G1
PORTMAN, R1
WICKEL, A1
Walsh, GM1
Buccafusco, JJ1
Spector, S1
Tompkins, JD1
Hancock, JC1

Other Studies

5 other studies available for dimethylphenylpiperazinium iodide and Hypertension

ArticleYear
α₂-Adrenoceptor-mediated inhibition of catecholamine release from the adrenal medulla of spontaneously hypertensive rats is preserved in the early stages of hypertension.
    Basic & clinical pharmacology & toxicology, 2011, Volume: 109, Issue:4

    Topics: Adrenal Medulla; Animals; Dimethylphenylpiperazinium Iodide; Epinephrine; Hypertension; Male; Medeto

2011
Evaluation of ganglionic blocking agents by blood pressure and by tension of the urinary bladder in dogs against 1,1-dimethyl-4-phenylpiperazinium iodide (DMPP).
    Archives internationales de pharmacodynamie et de therapie, 1954, Volume: 96, Issue:3-4

    Topics: Animals; Autonomic Agents; Autonomic Nervous System; Blood Pressure; Blood Pressure Determination; D

1954
Increased systemic vascular responsiveness to catecholamines in spontaneously hypertensive rats.
    Clinical and experimental hypertension. Part A, Theory and practice, 1983, Volume: 5, Issue:4

    Topics: Angiotensin II; Animals; Blood Pressure; Catecholamines; Dimethylphenylpiperazinium Iodide; Dose-Res

1983
Influence of clonidine on experimental hypertension induced by cholinergic stimulation.
    Experientia, 1980, Jun-15, Volume: 36, Issue:6

    Topics: Animals; Arecoline; Central Nervous System; Clonidine; Dimethylphenylpiperazinium Iodide; Hypertensi

1980
Electrophysiological effects of tachykinin agonists on sympathetic ganglia of spontaneously hypertensive rats.
    Autonomic neuroscience : basic & clinical, 2002, Apr-18, Volume: 97, Issue:1

    Topics: Analysis of Variance; Animals; Blood Pressure; Dimethylphenylpiperazinium Iodide; Dose-Response Rela

2002