Page last updated: 2024-10-20

thiamine and Hypertension

thiamine has been researched along with Hypertension in 24 studies

thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"Background: To examine the relation of dietary thiamine intake with risk of new-onset hypertension in the general adults."8.12U-Shaped Relation of Dietary Thiamine Intake and New-Onset Hypertension. ( He, P; Hou, F; Jiang, J; Liang, M; Liu, C; Liu, M; Qin, X; Wang, G; Wu, Q; Yang, S; Ye, Z; Zhang, Y; Zhou, C, 2022)
"The present study aimed to determine thiamine intake levels and the association between thiamine intake, diabetes, cardiovascular diseases and mental health."8.02Association between levels of thiamine intake, diabetes, cardiovascular diseases and depression in Korea: a national cross-sectional study. ( Duc, HN; Kim, MS; Oh, H; Yoon, IM, 2021)
"Novel strategies were coupled to position a new hypertension-susceptibility locus, uncovering a previously unsuspected thiamine transporter whose genetic variants predicted several disturbances in cardiac and autonomic function."7.80Genetic implication of a novel thiamine transporter in human hypertension. ( Corneveaux, JJ; Ehret, GB; Eskin, E; Hightower, CM; Huentelman, MJ; Mahata, M; Maihofer, AX; Miramontes-Gonzalez, JP; Nievergelt, CM; O'Connor, DT; Pastinen, T; Rao, F; Saier, MH; Schork, AJ; Schork, NJ; Sun, EI; Waalen, J; Wei, Z; Zhang, K, 2014)
" Thiamine repletion in CD36-defective SHR resulted in (1) the correction of the uncoupling of glucose oxidation to its cellular entry, concomitant with reduced protein O-GlcNAcylation, (2) the down-regulation of the expression of mRNAs involved in HBP, the renin-angiotensin system and adipokines in epididymal adipose tissue, and (3) the attenuation of the hypertension and hyperinsulinemia."7.74Thiamine attenuates the hypertension and metabolic abnormalities in CD36-defective SHR: uncoupling of glucose oxidation from cellular entry accompanied with enhanced protein O-GlcNAcylation in CD36 deficiency. ( Horie, R; Kitaura, Y; Kono, T; Miyazaki, M; Muramatsu, M; Ohkaru, Y; Sohmiya, K; Takai, S; Tanaka, T; Terasaki, F, 2007)
"Background: To examine the relation of dietary thiamine intake with risk of new-onset hypertension in the general adults."4.12U-Shaped Relation of Dietary Thiamine Intake and New-Onset Hypertension. ( He, P; Hou, F; Jiang, J; Liang, M; Liu, C; Liu, M; Qin, X; Wang, G; Wu, Q; Yang, S; Ye, Z; Zhang, Y; Zhou, C, 2022)
"The present study aimed to determine thiamine intake levels and the association between thiamine intake, diabetes, cardiovascular diseases and mental health."4.02Association between levels of thiamine intake, diabetes, cardiovascular diseases and depression in Korea: a national cross-sectional study. ( Duc, HN; Kim, MS; Oh, H; Yoon, IM, 2021)
"Novel strategies were coupled to position a new hypertension-susceptibility locus, uncovering a previously unsuspected thiamine transporter whose genetic variants predicted several disturbances in cardiac and autonomic function."3.80Genetic implication of a novel thiamine transporter in human hypertension. ( Corneveaux, JJ; Ehret, GB; Eskin, E; Hightower, CM; Huentelman, MJ; Mahata, M; Maihofer, AX; Miramontes-Gonzalez, JP; Nievergelt, CM; O'Connor, DT; Pastinen, T; Rao, F; Saier, MH; Schork, AJ; Schork, NJ; Sun, EI; Waalen, J; Wei, Z; Zhang, K, 2014)
"Low thiamine levels are associated with elevated blood glucose and hypertension in Saudi adults."3.79Thiamine and its phosphate esters in relation to cardiometabolic risk factors in Saudi Arabs. ( Abd-Alrahman, SH; Al-Attas, OS; Al-Daghri, NM; Alkharfy, KM; Alokail, MS; Sabico, S, 2013)
" Thiamine repletion in CD36-defective SHR resulted in (1) the correction of the uncoupling of glucose oxidation to its cellular entry, concomitant with reduced protein O-GlcNAcylation, (2) the down-regulation of the expression of mRNAs involved in HBP, the renin-angiotensin system and adipokines in epididymal adipose tissue, and (3) the attenuation of the hypertension and hyperinsulinemia."3.74Thiamine attenuates the hypertension and metabolic abnormalities in CD36-defective SHR: uncoupling of glucose oxidation from cellular entry accompanied with enhanced protein O-GlcNAcylation in CD36 deficiency. ( Horie, R; Kitaura, Y; Kono, T; Miyazaki, M; Muramatsu, M; Ohkaru, Y; Sohmiya, K; Takai, S; Tanaka, T; Terasaki, F, 2007)
" Reduction of dosage has an equivocal effect on gynaecological side affects-some increase, some decrease."1.26Human metabolism and steroid contraceptives. Part 2. ( Briggs, MH, 1977)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199013 (54.17)18.7374
1990's1 (4.17)18.2507
2000's5 (20.83)29.6817
2010's3 (12.50)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Zhang, Y2
Yang, S1
Ye, Z1
Wu, Q1
Liu, M1
Zhou, C1
He, P1
Jiang, J1
Liang, M1
Wang, G1
Hou, F1
Liu, C1
Qin, X1
Duc, HN1
Oh, H1
Yoon, IM1
Kim, MS1
Macchione, N1
Bernardini, P1
Piacentini, I1
Mangiarotti, B1
Del Nero, A1
Al-Daghri, NM1
Al-Attas, OS1
Alkharfy, KM1
Alokail, MS1
Abd-Alrahman, SH1
Sabico, S1
Zhang, K1
Huentelman, MJ1
Rao, F1
Sun, EI1
Corneveaux, JJ1
Schork, AJ1
Wei, Z1
Waalen, J1
Miramontes-Gonzalez, JP1
Hightower, CM1
Maihofer, AX1
Mahata, M1
Pastinen, T1
Ehret, GB1
Schork, NJ1
Eskin, E1
Nievergelt, CM1
Saier, MH1
O'Connor, DT1
Wang, C1
Li, Y1
Zhu, K1
Dong, YM1
Sun, CH1
Shikh, EV1
KOKHTAREVA, KA1
BOROSS, E1
HANDEL, M2
HERMANN, G2
WEISZ, P2
BOROS, E1
KOBAYASHI, T1
TAKEUCHI, M1
YAMATANI, A1
von KROGH, G1
Tanaka, T1
Sohmiya, K1
Kono, T1
Terasaki, F1
Horie, R1
Ohkaru, Y1
Muramatsu, M1
Takai, S1
Miyazaki, M1
Kitaura, Y1
Rieder, HP1
Berger, W1
Fridrich, R1
Olubodun, JO1
Lawal, SO1
Suter, PM1
Vetter, W1
Li, SQ1
Zhang, QH1
Briggs, MH1
Vernant, P1
Gaudeau, S1
Tillement, JP1
Derrida, JP1
Seftel, HC1
Metz, J1
Lakier, JB1
van der Molen, HR1
Lukkes, J1
Ritter, K1
King, JF1
Easton, R1
Dunn, M1
Braginskiĭ, BM1
Lis, MA1
Vodoevich, VP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Thiamin Supplementation on Thiamin Status in Children With Heart Disease Receiving Diuretic Drugs: Randomized Controlled Trial[NCT03989700]Phase 360 participants (Anticipated)Interventional2019-07-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for thiamine and Hypertension

ArticleYear
Diuretics and vitamin B1: are diuretics a risk factor for thiamin malnutrition?
    Nutrition reviews, 2000, Volume: 58, Issue:10

    Topics: Diuretics; Humans; Hypertension; Risk Factors; Thiamine; Thiamine Deficiency

2000
Advances in the development of functional foods from buckwheat.
    Critical reviews in food science and nutrition, 2001, Volume: 41, Issue:6

    Topics: Allergens; Animals; Carrier Proteins; China; Constipation; Diabetes Mellitus; Fagopyrum; Food Hypers

2001
[Complex intra-arterial, detoxicating, and dietetic treatment of intermittent claudication].
    Zentralblatt fur Phlebologie, 1968, Aug-15, Volume: 7, Issue:3

    Topics: Adult; Aged; Animals; Arteriosclerosis; Ascorbic Acid; Catecholamines; Diet Therapy; Dietary Fats; F

1968

Trials

2 trials available for thiamine and Hypertension

ArticleYear
Flower Pollen Extract in Association with Vitamins (Deprox 500®) Versus Serenoa repens in Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Comparative Analysis of Two Different Treatments.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2019, Volume: 18, Issue:2

    Topics: Adult; Aged; Disease Progression; Drug Combinations; Folic Acid; Humans; Hypertension; Male; Middle

2019
Effects of supplementation with multivitamin and mineral on blood pressure and C-reactive protein in obese Chinese women with increased cardiovascular disease risk.
    Asia Pacific journal of clinical nutrition, 2009, Volume: 18, Issue:1

    Topics: Adolescent; Blood Pressure; C-Reactive Protein; Calcium; China; Dietary Supplements; Double-Blind Me

2009

Other Studies

19 other studies available for thiamine and Hypertension

ArticleYear
U-Shaped Relation of Dietary Thiamine Intake and New-Onset Hypertension.
    Nutrients, 2022, Aug-09, Volume: 14, Issue:16

    Topics: Adult; Blood Pressure; Diet; Humans; Hypertension; Nutrition Surveys; Thiamine

2022
Association between levels of thiamine intake, diabetes, cardiovascular diseases and depression in Korea: a national cross-sectional study.
    Journal of nutritional science, 2021, Volume: 10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Child; Child, Preschool; Cross-

2021
Thiamine and its phosphate esters in relation to cardiometabolic risk factors in Saudi Arabs.
    European journal of medical research, 2013, Sep-23, Volume: 18

    Topics: Adult; Aging; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Diastole; Esters; Female; Hu

2013
Genetic implication of a novel thiamine transporter in human hypertension.
    Journal of the American College of Cardiology, 2014, Apr-22, Volume: 63, Issue:15

    Topics: Adult; Alleles; Blood Pressure; DNA; Female; Genetic Predisposition to Disease; Genome-Wide Associat

2014
[Urine levels of thiamine and riboflavine in diuretic therapy of patients with cardiovascular diseases].
    Klinicheskaia meditsina, 2002, Volume: 80, Issue:7

    Topics: Diuretics; Female; Humans; Hypertension; Male; Middle Aged; Pyridoxine; Riboflavin; Thiamine

2002
[Relationship between vitamin B1, cocarboxylase, pyroacetic acid, lactic acid, and inorganic phosphorus in hypertension].
    Trudy. Institut grudnoi khirurgii (Akademiia meditsinskikh nauk SSSR), 1952, Volume: 20

    Topics: Acids; Humans; Hypertension; Lactic Acid; Phosphorus; Thiamine; Thiamine Pyrophosphate

1952
[Effect of aneurin on experimental neurogenic hypertension in rats].
    Magyar belorvosi archivum (1955), 1955, Volume: 8, Issue:4

    Topics: Animals; Autonomic Nervous System Diseases; Hypertension; Rats; Thiamine

1955
[Effects of vitamin B1 on experimental neurogenic hypertension in rats].
    Acta physiologica Academiae Scientiarum Hungaricae, 1956, Volume: 9, Issue:1-3

    Topics: Animals; Hypertension; Rats; Thiamine

1956
[REHABILITATION IN HEART DISEASE].
    [Chiryo] [Therapy], 1963, Volume: 45

    Topics: Acenocoumarol; Dipyridamole; Electrocardiography; Geriatrics; Heart Defects, Congenital; Heart Disea

1963
[THE QUANTITY OF EVENING DRINKING AND VITAMIN B1 METABOLISM IN A MINING AREA IN AKITA-KEN].
    The Journal of nutrition, 1964, Volume: 24

    Topics: Alcohol Drinking; Alcoholic Beverages; Diet; Humans; Hypertension; Japan; Metabolism; Mining; Thiami

1964
[Clinical observations on the effect of a neurotropic agent on the blood circulation].
    Arztliche Forschung, 1962, Aug-10, Volume: 16

    Topics: Amino Alcohols; Caffeine; Humans; Hypertension; Hypotension; Thiamine

1962
Thiamine attenuates the hypertension and metabolic abnormalities in CD36-defective SHR: uncoupling of glucose oxidation from cellular entry accompanied with enhanced protein O-GlcNAcylation in CD36 deficiency.
    Molecular and cellular biochemistry, 2007, Volume: 299, Issue:1-2

    Topics: Acetylglucosamine; Acylation; Animals; Base Sequence; CD36 Antigens; DNA Primers; Glucose; Glycosyla

2007
[Vitamin status in diabetic neuropathy (thiamine, riboflavin, pyridoxin, cobalamin and tocopherol)].
    Zeitschrift fur Ernahrungswissenschaft, 1980, Volume: 19, Issue:1

    Topics: Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathies; Diabetic Retinopathy; Female; Huma

1980
Alcohol consumption and heart failure in hypertensives.
    International journal of cardiology, 1996, Volume: 53, Issue:1

    Topics: Adult; Aged; Alcohol Drinking; Cardiac Output, Low; Female; Humans; Hypertension; Male; Middle Aged;

1996
Human metabolism and steroid contraceptives. Part 2.
    Australian family physician, 1977, Volume: Suppl

    Topics: Ascorbic Acid; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Dose-Response Relationship, Dr

1977
[Hyperkinetic syndromes associated with hypothiaminemia and corrected by administration of vitamin B 1].
    Archives des maladies du coeur et des vaisseaux, 1976, Volume: 69, Issue:10

    Topics: Adolescent; Adult; Cardiac Output; Cardiomyopathies; Diagnosis, Differential; Female; Humans; Hypert

1976
Cardiomyopathies in Johannesburg Bantu. I. Aetiology and characteristics of beriberi heart disease.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972, Nov-11, Volume: 46, Issue:45

    Topics: Adult; Alcohol Drinking; Beriberi; Black or African American; Black People; Cardiomegaly; Erythrocyt

1972
Acute pernicious beriberi heart disease.
    Chest, 1972, Volume: 61, Issue:5

    Topics: Acidosis; Acute Disease; Adult; Alcoholism; Beriberi; Bicarbonates; Cardiac Output; Cardiomyopathies

1972
[Thiamine supply and metabolic peculiarities in patients with hypertension and arteriosclerotic cardiosclerosis].
    Sovetskaia meditsina, 1971, Volume: 34, Issue:4

    Topics: Adult; Arteriosclerosis; Coronary Disease; Humans; Hypertension; Thiamine

1971