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ethylisopropylamiloride and Hypertension

ethylisopropylamiloride has been researched along with Hypertension in 8 studies

ethylisopropylamiloride: structure in first source
ethylisopropylamiloride : A member of the class of pyrazines that is amiloride in which the amino substitutent of the pyrazine ring that is adjacent to the chloro substituent has been substituted by an ethyl group and by an isopropyl group.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"The aim was to investigate the effect of ethylisopropylamiloride (EIPA), an inhibitor of Na+/H+ exchange, and of extracellular pH on the proliferation of immortalised lymphoblasts derived from patients with essential hypertension and normotensive controls."3.69Role of sodium-hydrogen exchange in the proliferation of immortalised lymphoblasts from patients with essential hypertension and normotensive subjects. ( Rosskopf, D; Schröder, KJ; Siffert, W, 1995)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (75.00)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chau, WH1
Lee, WH1
Lau, WH1
Kwan, YW1
Au, AL1
Raymond, K1
Rosskopf, D1
Schröder, KJ1
Siffert, W1
Orlov, SN2
Kuznetsov, SR1
Pokudin, NI1
Tremblay, J2
Hamet, P2
Adarichev, VA1
Devlin, AM1
Maximova, NV1
Sun, YL1
Dominiczak, AF1
Postnov, YV1
Inariba, H1
Kanayama, Y1
Takaori, K1
Negoro, N1
Inoue, T1
Takeda, T1
Parenti, P1
Ferrari, P1
Ferrandi, M1
Hanozet, GM1
Bianchi, G1
Izzard, AS1
Cragoe, EJ1
Heagerty, AM1
Gesek, FA1
Schoolwerth, AC1

Other Studies

8 other studies available for ethylisopropylamiloride and Hypertension

ArticleYear
Role of Na+/H+ exchanger in acetylcholine-mediated pulmonary artery contraction of spontaneously hypertensive rats.
    European journal of pharmacology, 2003, Mar-19, Volume: 464, Issue:2-3

    Topics: Acetylcholine; Amiloride; Animals; Calcium; Cholinesterase Inhibitors; Dose-Response Relationship, D

2003
Role of sodium-hydrogen exchange in the proliferation of immortalised lymphoblasts from patients with essential hypertension and normotensive subjects.
    Cardiovascular research, 1995, Volume: 29, Issue:2

    Topics: Amiloride; Anti-Arrhythmia Agents; Cell Cycle; Cell Division; Cell Line; Humans; Hydrogen-Ion Concen

1995
Can we use erythrocytes for the study of the activity of the ubiquitous Na+/H+ exchanger (NHE-1) in essential hypertension?
    American journal of hypertension, 1998, Volume: 11, Issue:7

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Amiloride; Animals; Anti-A

1998
Increased Na(+)/H(+) exchanger isoform 1 activity in spontaneously hypertensive rats: lack of mutations within the coding region of NHE1.
    Biochimica et biophysica acta, 2000, Feb-21, Volume: 1500, Issue:2

    Topics: Amiloride; Animals; Aorta; Cells, Cultured; Crosses, Genetic; DNA Mutational Analysis; DNA, Compleme

2000
Increased Na+/H+ exchange activity in vascular smooth muscle cells of spontaneously hypertensive rats and possible involvement of protein kinase C.
    Clinical and experimental pharmacology & physiology, 1992, Volume: 19, Issue:3

    Topics: Amiloride; Animals; Calcium; Calmodulin; Carrier Proteins; Cells, Cultured; Hypertension; Male; Musc

1992
Effect of amiloride analogues on sodium transport in renal brush border membrane vesicles from Milan hypertensive rats.
    Biochemical and biophysical research communications, 1992, Feb-28, Volume: 183, Issue:1

    Topics: Amiloride; Animals; Biological Transport, Active; Hypertension; Kidney; Membrane Potentials; Microvi

1992
Intracellular pH in human resistance arteries in essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:6 Pt 1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo

1991
Insulin increases Na(+)-H+ exchange activity in proximal tubules from normotensive and hypertensive rats.
    The American journal of physiology, 1991, Volume: 260, Issue:5 Pt 2

    Topics: Adrenergic alpha-Agonists; Amiloride; Angiotensin II; Animals; Blood Pressure; Carrier Proteins; Cyc

1991