Page last updated: 2024-11-02

oxybutynin and Hypertension

oxybutynin has been researched along with Hypertension in 16 studies

oxybutynin: RN given refers to parent cpd
oxybutynin : A racemate comprising equimolar amounts of (R)-oxybutynin and esoxybutynin. An antispasmodic used for the treatment of overactive bladder.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"TY-0201 (TY) is a new drug absorbed by the transdermal delivery system developed for the treatment of hypertension, which contains the free base of bisoprolol fumarate that is widely used."9.17Comparison of efficacy and safety between bisoprolol transdermal patch (TY-0201) and bisoprolol fumarate oral formulation in Japanese patients with grade I or II essential hypertension: randomized, double-blind, placebo-controlled study. ( Kuwajima, I; Matsuoka, H; Mitamura, H; Saruta, T; Shimada, K, 2013)
"However, orthostatic hypotension (OH) is sometimes caused by BBs."5.56Bisoprolol transdermal patch improves orthostatic hypotension in patients with chronic heart failure and hypertension. ( Dobashi, S; Fujii, T; Hisatake, S; Ikeda, T; Kabuki, T; Kiuchi, S; Oka, T; Sano, T, 2020)
"TY-0201 (TY) is a new drug absorbed by the transdermal delivery system developed for the treatment of hypertension, which contains the free base of bisoprolol fumarate that is widely used."5.17Comparison of efficacy and safety between bisoprolol transdermal patch (TY-0201) and bisoprolol fumarate oral formulation in Japanese patients with grade I or II essential hypertension: randomized, double-blind, placebo-controlled study. ( Kuwajima, I; Matsuoka, H; Mitamura, H; Saruta, T; Shimada, K, 2013)
"It was concluded that timolol maleate patch could be formulated into a matrix-type transdermal patch for the management of hypertension."3.88Design and Evaluation of Transdermal Patches of Timolol Maleate. ( Jamakandi, VG; Panchayya Hiremath, SS; Reddy, JJ, 2018)
"To determine whether there is greater risk of initiation of oxybutynin to treat urinary incontinence (UI) after initiation of medicines reported to be associated with UI."3.80Risk of medication-associated initiation of oxybutynin in elderly men and women. ( Barratt, JD; Kalisch Ellett, LM; Pratt, NL; Roughead, EE; Rowett, D, 2014)
" We report a 4-year-old girl who presented with acute bilateral blindness, a focal seizure and hypertension 10 days after commencing oxybutynin to treat enuresis."3.74Transient bilateral blindness and posterior reversible encephalopathy syndrome: a rare complication of enuresis treatment. ( Branson, JA; Dale, RC, 2008)
" GTN appears safe in ipsilateral or bilateral carotid stenosis, and might improve outcome in severe ipsilateral carotid stenosis."2.90It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis. ( Appleton, JP; Bath, PM; Belcher, A; Bereczki, D; Berge, E; Caso, V; Chang, HM; Christensen, HK; Collins, R; Gommans, J; Laska, AC; Ntaios, G; Ozturk, S; Sare, GM; Sprigg, N; Szatmari, S; Wang, Y; Wardlaw, JM; Woodhouse, LJ, 2019)
"High blood pressure is a common complication in acute stroke and is associated with a poor outcome."2.76The effect of transdermal glyceryl trinitrate on 24 h ambulatory blood pressure in acute/subacute stroke. ( Bath, AJ; Bath, PM; Geeganage, CM, 2011)
" It compares the bioavailability of these two study drugs from a TDDS with conventional immediate release oral tablets in healthy volunteers."2.75Randomised, cross-over, comparative bioavailability trial of matrix type transdermal drug delivery system (TDDS) of carvedilol and hydrochlorothiazide combination in healthy human volunteers: a pilot study. ( Aggarwal, A; Agrawal, SS, 2010)
" Patient adherence theoretically could be improved due to ease of use and once-daily dosing when compared to oral counterparts' need for multiple daily doses."2.52A critical appraisal of the selegiline transdermal system for major depressive disorder. ( Bied, AM; Kim, J; Schwartz, TL, 2015)
"However, orthostatic hypotension (OH) is sometimes caused by BBs."1.56Bisoprolol transdermal patch improves orthostatic hypotension in patients with chronic heart failure and hypertension. ( Dobashi, S; Fujii, T; Hisatake, S; Ikeda, T; Kabuki, T; Kiuchi, S; Oka, T; Sano, T, 2020)
"Paroxysmal autonomic instability with dystonia (PAID) is an underdiagnosed syndrome that describes a collection of symptoms following diverse cerebral insults, such as traumatic brain injury, hydrocephalus, hemorrhagic stroke, or brain anoxia."1.56Transdermal opioid patch in treatment of paroxysmal autonomic instability with dystonia with multiple cerebral insults: A case report. ( Baik, SW; Kang, DH; Kim, GW, 2020)
"Her hypertension and sinus tachycardia peaked 8 and 5 h after all the patches were removed, respectively."1.46Acute cholinergic syndrome in a patient with mild Alzheimer's type dementia who had applied a large number of rivastigmine transdermal patches on her body. ( Fujita, Y; Kamijo, Y; Kishino, T; Suzuki, Y; Usui, K; Yoshizawa, T, 2017)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.25)29.6817
2010's13 (81.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Kalisch Ellett, LM1
Pratt, NL1
Barratt, JD1
Rowett, D1
Roughead, EE1
Branson, JA1
Dale, RC1
Kiuchi, S1
Hisatake, S1
Kabuki, T1
Oka, T1
Dobashi, S1
Fujii, T1
Sano, T1
Ikeda, T1
Baik, SW1
Kang, DH1
Kim, GW1
Suzuki, Y1
Kamijo, Y1
Yoshizawa, T1
Fujita, Y1
Usui, K1
Kishino, T1
Panchayya Hiremath, SS1
Reddy, JJ1
Jamakandi, VG1
Radwan, RR1
Mohamed, HA1
Ali, HE1
Mahmoud, GA1
Sairaku, A1
Nakano, Y1
Shiode, N1
Suenari, K1
Oda, N1
Ono, K1
Kihara, Y1
Appleton, JP1
Woodhouse, LJ1
Belcher, A1
Bereczki, D1
Berge, E1
Caso, V1
Chang, HM1
Christensen, HK1
Collins, R1
Gommans, J1
Laska, AC1
Ntaios, G1
Ozturk, S1
Sare, GM1
Szatmari, S1
Wang, Y1
Wardlaw, JM1
Sprigg, N1
Bath, PM2
Matsuoka, H1
Kuwajima, I1
Shimada, K1
Mitamura, H1
Saruta, T1
Posadzy-Malaczynska, A1
Rajpold, K1
Woznicka-Leskiewicz, L1
Marcinkowska, J1
Hara, T1
Yagi, S1
Akaike, M1
Sata, M1
Bied, AM1
Kim, J1
Schwartz, TL1
Kienstra, CM1
Hergenroeder, AC1
Riley, AA1
Justino, H1
Agrawal, SS1
Aggarwal, A1
Geeganage, CM1
Bath, AJ1

Reviews

1 review available for oxybutynin and Hypertension

ArticleYear
A critical appraisal of the selegiline transdermal system for major depressive disorder.
    Expert review of clinical pharmacology, 2015, Volume: 8, Issue:6

    Topics: Administration, Cutaneous; Antidepressive Agents; Depressive Disorder, Major; Drug Liberation; Human

2015

Trials

5 trials available for oxybutynin and Hypertension

ArticleYear
It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis.
    Stroke and vascular neurology, 2019, Volume: 4, Issue:1

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Carotid

2019
Comparison of efficacy and safety between bisoprolol transdermal patch (TY-0201) and bisoprolol fumarate oral formulation in Japanese patients with grade I or II essential hypertension: randomized, double-blind, placebo-controlled study.
    Journal of clinical hypertension (Greenwich, Conn.), 2013, Volume: 15, Issue:11

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Asian People; Bisoprolol; Blood Pressure; Dose

2013
Hemodynamic and metabolic effects of estrogen plus progestin therapy in hypertensive postmenopausal women treated with an ACE-inhibitor or a diuretic.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2015, Volume: 104, Issue:1

    Topics: Administration, Cutaneous; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Blood Pressure; Blo

2015
Randomised, cross-over, comparative bioavailability trial of matrix type transdermal drug delivery system (TDDS) of carvedilol and hydrochlorothiazide combination in healthy human volunteers: a pilot study.
    Contemporary clinical trials, 2010, Volume: 31, Issue:4

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Antihypertensive Agents; Area Under Curve; B

2010
The effect of transdermal glyceryl trinitrate on 24 h ambulatory blood pressure in acute/subacute stroke.
    International journal of stroke : official journal of the International Stroke Society, 2011, Volume: 6, Issue:4

    Topics: Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Female; Humans; Hypertension; Male; Nit

2011

Other Studies

10 other studies available for oxybutynin and Hypertension

ArticleYear
Risk of medication-associated initiation of oxybutynin in elderly men and women.
    Journal of the American Geriatrics Society, 2014, Volume: 62, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Age Factors; Aged; Aged, 80 and over; Dose-Response Relatio

2014
Transient bilateral blindness and posterior reversible encephalopathy syndrome: a rare complication of enuresis treatment.
    Journal of paediatrics and child health, 2008, Volume: 44, Issue:6

    Topics: Blindness; Child, Preschool; Cholinergic Antagonists; Enuresis; Female; Humans; Hypertension; Magnet

2008
Bisoprolol transdermal patch improves orthostatic hypotension in patients with chronic heart failure and hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2020, Aug-17, Volume: 42, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Bisoprolol; Blood Pressure; Female; Heart Failure; Humans; Hypert

2020
Transdermal opioid patch in treatment of paroxysmal autonomic instability with dystonia with multiple cerebral insults: A case report.
    Medicine, 2020, Oct-02, Volume: 99, Issue:40

    Topics: Analgesics, Opioid; Autonomic Nervous System Diseases; Basal Ganglia; Brain Ischemia; Diffusion Tens

2020
Acute cholinergic syndrome in a patient with mild Alzheimer's type dementia who had applied a large number of rivastigmine transdermal patches on her body.
    Clinical toxicology (Philadelphia, Pa.), 2017, Volume: 55, Issue:9

    Topics: Administration, Cutaneous; Aged, 80 and over; Alzheimer Disease; Blood Pressure; Cholinesterase Inhi

2017
Design and Evaluation of Transdermal Patches of Timolol Maleate.
    Current drug delivery, 2018, Volume: 15, Issue:5

    Topics: Acrylic Resins; Administration, Cutaneous; Animals; Antihypertensive Agents; Cellulose; Drug Liberat

2018
Radiation preparation of L-arginine/acrylic acid hydrogel matrix patch for transdermal delivery of propranolol HCl in hypertensive rats.
    Drug delivery and translational research, 2018, Volume: 8, Issue:3

    Topics: Acrylates; Administration, Cutaneous; Animals; Antihypertensive Agents; Arginine; Blood Pressure; Dr

2018
Head-to-head comparison of the heart rate variability between the bisoprolol transdermal patch and bisoprolol fumarate tablet.
    Cardiovascular therapeutics, 2018, Volume: 36, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Antihypertensive Agents; Bisoprolol; Female; H

2018
Transdermal patch of bisoprolol for the treatment of hypertension complicated with aortic dissection.
    International journal of cardiology, 2015, Nov-01, Volume: 198

    Topics: Antihypertensive Agents; Aortic Aneurysm; Aortic Dissection; Bisoprolol; Humans; Hypertension; Male;

2015
Hypertension in an Adolescent Athlete.
    Clinical pediatrics, 2016, Volume: 55, Issue:12

    Topics: Adolescent; Arterial Occlusive Diseases; Athletes; Clonidine; Humans; Hypertension; Male; Time Facto

2016