Page last updated: 2024-09-25

statine

Description

statine: amine component of pepstatin; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID123915
SCHEMBL ID8594
MeSH IDM0060721

Synonyms (21)

Synonym
heptanoic acid, 4-amino-3-hydroxy-6-methyl-, (3s,4s)-
inchi=1/c8h17no3/c1-5(2)3-6(9)7(10)4-8(11)12/h5-7,10h,3-4,9h2,1-2h3,(h,11,12)/t6-,7-/m0/s
(3s,4s)-4-amino-3-hydroxy-6-methylheptanoic acid
statine
49642-07-1
unii-ytc77xr1ek
ytc77xr1ek ,
DFVFTMTWCUHJBL-BQBZGAKWSA-N
SCHEMBL8594
(3s,4s)-statine
statine [mi]
statine, (-)-
HY-101877
CS-7998
(3s,4s)-(-)-statine
AKOS028114708
mfcd00037277
(3s,4s)-4-amino-3-hydroxy-6-methylheptanoic acid hydrochloride
Q7604197
DTXSID00964315
(3s,4s)-4-amino-3-hydroxy-6-methyl-heptanoic acid

Research

Studies (120)

TimeframeStudies, This Drug (%)All Drugs %
pre-199027 (22.50)18.7374
1990's24 (20.00)18.2507
2000's27 (22.50)29.6817
2010's41 (34.17)24.3611
2020's1 (0.83)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials6 (4.69%)5.53%
Reviews8 (6.25%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other114 (89.06%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research Highlights

Pharmacokinetics (1)

ArticleYear
Effects of statin therapy on coronary artery plaque volume and high-risk plaque morphology in HIV-infected patients with subclinical atherosclerosis: a randomised, double-blind, placebo-controlled trial.
The lancet. HIV, Volume: 2, Issue: 2
2015
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (3)

ArticleYear
Modified-policosanol does not reduce plasma lipoproteins in hyperlipidemic patients when used alone or in combination with statin therapy.
Lipids, Volume: 46, Issue: 10
2011
HIV proteinase inhibitors containing 2-aminobenzylstatine as a novel scissile bond replacement: biochemical and pharmacological characterization.
Antiviral research, Volume: 25, Issue: 3-4
1994
Why renin inhibitors?
Journal of hypertension. Supplement : official journal of the International Society of Hypertension, Volume: 7, Issue: 2
1989
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Interactions (1)

ArticleYear
Modified-policosanol does not reduce plasma lipoproteins in hyperlipidemic patients when used alone or in combination with statin therapy.
Lipids, Volume: 46, Issue: 10
2011
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]