hydrogen has been researched along with Hypertension in 39 studies
Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The study was undertaken to determine the possible effect of an aldosterone antagonist, spironolactone (SP), on red blood cell sodium-hydrogen exchange (NHE) enhancement in primary aldosteronism (PA) and essential hypertension (EH)." | 9.08 | Spironolactone prevents Na+/H+ exchange enhancement in primary aldosteronism. ( Koldanov, R; Koren, W; Postnov, IY; Postnov, YV, 1997) |
| " An association has been described between increased sodium/hydrogen (Na+/H+) exchange rates in various cells and microalbuminuria in type 1 diabetic patients." | 7.69 | Characteristics of the sodium/hydrogen exchange in non-insulin-dependent diabetic patients with microalbuminuria and hypertension. ( Yudkin, JS; Zaidi, KF, 1996) |
| "Hypertension is one of the major issues worldwide and one of the main factors involved in heart and kidney failure." | 5.72 | Structural and dynamic investigation of non-synonymous variations in Renin-AGT complex revealed altered binding via hydrogen-bonding network reprogramming to accelerate the hypertension pathway. ( Ahmad, H; Khan, A; Khan, T; Tian, Z; Umbreen, S; Wei, DQ; Xuewei, Z, 2022) |
| "Hypertension is an important risk factor for death resulting from stroke, myocardial infarction, and end-stage renal failure." | 5.51 | Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension. ( Hashimoto, K; Ichihara, M; Iwamoto, T; Kato, K; Matsuoka, H; Miyata, S; Nagahara, M; Noda, A; Okumura, N; Sobue, S; Takeda, K; Watanabe, T, 2019) |
| "In conclusion, HRS treatment attenuates left ventricular hypertrophy through abating oxidative stress, suppressing inflammatory process, preserving mitochondrial function, in which suppression of HRS on angiotensin II in left ventricles locally might be involved." | 5.38 | Chronic hydrogen-rich saline treatment reduces oxidative stress and attenuates left ventricular hypertrophy in spontaneous hypertensive rats. ( Yu, YS; Zheng, H, 2012) |
| "The study was undertaken to determine the possible effect of an aldosterone antagonist, spironolactone (SP), on red blood cell sodium-hydrogen exchange (NHE) enhancement in primary aldosteronism (PA) and essential hypertension (EH)." | 5.08 | Spironolactone prevents Na+/H+ exchange enhancement in primary aldosteronism. ( Koldanov, R; Koren, W; Postnov, IY; Postnov, YV, 1997) |
| "Using 31-phosphorus magnetic resonance spectroscopy, pHi of the dominant flexor digitorum superficialis was measured in 20 Caucasian subjects (14 male) with essential hypertension and 20 normotensive controls matched for gender, age, race and body mass index." | 3.71 | In-vivo intracellular pH at rest and during exercise in patients with essential hypertension. ( Baker, EH; Griffiths, JR; Khong, TK; MacGregor, GA; Markandu, ND; McIntyre, DJ; Miller, MA; Sagnella, GA, 2001) |
| " An association has been described between increased sodium/hydrogen (Na+/H+) exchange rates in various cells and microalbuminuria in type 1 diabetic patients." | 3.69 | Characteristics of the sodium/hydrogen exchange in non-insulin-dependent diabetic patients with microalbuminuria and hypertension. ( Yudkin, JS; Zaidi, KF, 1996) |
| "Hypertension is one of the major issues worldwide and one of the main factors involved in heart and kidney failure." | 1.72 | Structural and dynamic investigation of non-synonymous variations in Renin-AGT complex revealed altered binding via hydrogen-bonding network reprogramming to accelerate the hypertension pathway. ( Ahmad, H; Khan, A; Khan, T; Tian, Z; Umbreen, S; Wei, DQ; Xuewei, Z, 2022) |
| "Hypertension is an important risk factor for death resulting from stroke, myocardial infarction, and end-stage renal failure." | 1.51 | Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension. ( Hashimoto, K; Ichihara, M; Iwamoto, T; Kato, K; Matsuoka, H; Miyata, S; Nagahara, M; Noda, A; Okumura, N; Sobue, S; Takeda, K; Watanabe, T, 2019) |
| "In conclusion, HRS treatment attenuates left ventricular hypertrophy through abating oxidative stress, suppressing inflammatory process, preserving mitochondrial function, in which suppression of HRS on angiotensin II in left ventricles locally might be involved." | 1.38 | Chronic hydrogen-rich saline treatment reduces oxidative stress and attenuates left ventricular hypertrophy in spontaneous hypertensive rats. ( Yu, YS; Zheng, H, 2012) |
| "Hypertension is an additional factor associated with a high degree of renal involvement in IDDM." | 1.29 | Platelet Na+/H+ antiport activity in patients with insulin-dependent diabetes mellitus with and without diabetic nephropathy. ( Düsing, R; Göbel, BO; Hoffmann, G; Mattes, L; Rosskopf, D; Siffert, W; Sorger, M; Vetter, H, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (38.46) | 18.7374 |
| 1990's | 15 (38.46) | 18.2507 |
| 2000's | 2 (5.13) | 29.6817 |
| 2010's | 4 (10.26) | 24.3611 |
| 2020's | 3 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Kawakami, K | 1 |
| Matsuo, H | 1 |
| Yamada, T | 1 |
| Matsumoto, KI | 1 |
| Sasaki, D | 1 |
| Nomura, M | 1 |
| Ahmad, H | 1 |
| Khan, A | 1 |
| Umbreen, S | 1 |
| Khan, T | 1 |
| Xuewei, Z | 1 |
| Wei, DQ | 1 |
| Tian, Z | 1 |
| Yamamoto, H | 1 |
| Ichikawa, Y | 1 |
| Hirano, SI | 1 |
| Sato, B | 1 |
| Takefuji, Y | 1 |
| Satoh, F | 1 |
| Matsuoka, H | 1 |
| Miyata, S | 1 |
| Okumura, N | 1 |
| Watanabe, T | 1 |
| Hashimoto, K | 1 |
| Nagahara, M | 1 |
| Kato, K | 1 |
| Sobue, S | 1 |
| Takeda, K | 1 |
| Ichihara, M | 1 |
| Iwamoto, T | 1 |
| Noda, A | 1 |
| Jin, C | 1 |
| Sun, J | 1 |
| Stilphen, CA | 1 |
| Smith, SM | 1 |
| Ocasio, H | 1 |
| Bermingham, B | 1 |
| Darji, S | 1 |
| Guha, A | 1 |
| Patel, R | 1 |
| Geurts, AM | 1 |
| Jacob, HJ | 1 |
| Lambert, NA | 1 |
| O'Connor, PM | 1 |
| Takeuchi, S | 1 |
| Nagatani, K | 1 |
| Otani, N | 1 |
| Nawashiro, H | 1 |
| Sugawara, T | 1 |
| Wada, K | 1 |
| Mori, K | 1 |
| Yu, YS | 1 |
| Zheng, H | 1 |
| GERARD, R | 1 |
| REDON, A | 1 |
| BENYAMINE, R | 1 |
| MOLINIER, A | 1 |
| Navarro-Lopez, F | 1 |
| Coca, A | 1 |
| Pare, JC | 1 |
| De La Sierra, A | 1 |
| Bosch, X | 1 |
| Urbano Marquez, A | 1 |
| Scholz, TD | 1 |
| Ceckler, TL | 1 |
| Balaban, RS | 1 |
| Düsing, R | 1 |
| Sorger, M | 1 |
| Mattes, L | 1 |
| Göbel, BO | 1 |
| Hoffmann, G | 1 |
| Rosskopf, D | 1 |
| Vetter, H | 1 |
| Siffert, W | 1 |
| Zaidi, KF | 1 |
| Yudkin, JS | 1 |
| Koren, W | 1 |
| Koldanov, R | 1 |
| Postnov, IY | 1 |
| Postnov, YV | 1 |
| Sakaeda, T | 1 |
| Fukumura, K | 1 |
| Takahashi, K | 1 |
| Matsumura, S | 1 |
| Matsuura, E | 1 |
| Hirano, K | 1 |
| Khong, TK | 1 |
| McIntyre, DJ | 1 |
| Sagnella, GA | 1 |
| Markandu, ND | 1 |
| Miller, MA | 1 |
| Baker, EH | 1 |
| Griffiths, JR | 1 |
| MacGregor, GA | 1 |
| Yasuda, T | 1 |
| Shigematsu, J | 1 |
| Tobimatsu, S | 1 |
| Takahashi, S | 1 |
| Kato, M | 1 |
| Moggio, RA | 1 |
| Hammond, GL | 1 |
| Cloix, JF | 1 |
| Le Jossec, M | 1 |
| Baud, O | 1 |
| Pecquery, R | 1 |
| Giudicelli, Y | 1 |
| Dausse, JP | 1 |
| Acra, S | 1 |
| Ghishan, FK | 1 |
| Syme, PD | 1 |
| Aronson, JK | 1 |
| Thompson, CH | 1 |
| Williams, EM | 1 |
| Green, Y | 1 |
| Radda, GK | 2 |
| Semplicini, A | 1 |
| Ceolotto, G | 1 |
| Marzola, M | 1 |
| Delva, P | 1 |
| Pastori, C | 1 |
| Degan, M | 1 |
| Zamboni, M | 1 |
| Arosio, E | 1 |
| Lechi, C | 1 |
| Guzzo, P | 1 |
| Armellini, F | 1 |
| Lechi, A | 1 |
| Strazzullo, P | 1 |
| de Simone, G | 1 |
| Celentano, A | 1 |
| Iacone, R | 1 |
| Ragone, E | 1 |
| Pagano, E | 1 |
| Tammaro, P | 1 |
| Canessa, M | 1 |
| Nosadini, R | 1 |
| Crepaldi, G | 1 |
| D'Angelo, A | 1 |
| Kobayashi, A | 1 |
| Nara, Y | 1 |
| Nishio, T | 1 |
| Mori, C | 1 |
| Yamori, Y | 1 |
| Dudley, CR | 1 |
| Taylor, DJ | 1 |
| Ng, LL | 1 |
| Kemp, GJ | 1 |
| Ratcliffe, PJ | 1 |
| Ledingham, JG | 1 |
| Astarie, C | 1 |
| Levenson, J | 1 |
| Simon, A | 1 |
| Meyer, P | 1 |
| Devynck, MA | 1 |
| Smith, JM | 1 |
| Cragoe, EJ | 1 |
| Jones, AW | 1 |
| Thorén, P | 1 |
| Westling, H | 1 |
| Skarphedinsson, JO | 1 |
| Livne, A | 2 |
| Balfe, JW | 1 |
| Veitch, R | 1 |
| Marquez-Julio, A | 1 |
| Grinstein, S | 1 |
| Rothstein, A | 1 |
| Stokes, GS | 1 |
| Monaghan, JC | 1 |
| Marwood, JF | 1 |
| Aviv, A | 2 |
| Mahnensmith, RL | 1 |
| Aronson, PS | 1 |
| Weissberg, PL | 1 |
| Little, PJ | 1 |
| Bobik, A | 1 |
| Pokudin, NI | 1 |
| Orlov, SN | 1 |
| Postnov, IuV | 1 |
| Meyer, JS | 1 |
| Welch, KM | 1 |
| Koberstein, RC | 1 |
| Pittman, DE | 1 |
| Klocke, FJ | 1 |
| Grünfeld, JP | 1 |
| Raphaël, JC | 1 |
| Bankir, L | 1 |
| Kleinknecht, D | 1 |
| Barger, AC | 1 |
8 reviews available for hydrogen and Hypertension
| Article | Year |
|---|---|
Molecular Hydrogen as a Novel Protective Agent against Pre-Symptomatic Diseases.
Topics: Alzheimer Disease; Animals; Asymptomatic Diseases; Chronic Disease; Diabetes Mellitus, Type 2; Free | 2021 |
[Na+/H+ exchangers, alpha-2-adrenergic receptors, sodium sensitivity and arterial hypertension].
Topics: Animals; Drug Resistance; Hydrogen; Hypertension; Ion Transport; Rats; Rats, Inbred Strains; Recepto | 1992 |
[Erythrocyte Na+/H+ exchange and arterial hypertension].
Topics: Bicarbonates; Biochemical Phenomena; Biochemistry; Electrochemistry; Erythrocytes; Humans; Hydrogen; | 1991 |
The link between cytosolic Ca2+ and the Na+-H+ antiport: a unifying factor for essential hypertension.
Topics: Animals; Atrial Natriuretic Factor; Biological Transport; Calcium; Cytosol; Dopamine; Humans; Hydrog | 1988 |
The plasma membrane sodium-hydrogen exchanger and its role in physiological and pathophysiological processes.
Topics: Acid-Base Equilibrium; Animals; Biological Transport, Active; Blood Platelets; Calcium; Carrier Prot | 1985 |
The Na+/H+ antiport, cytosolic free Ca2+, and essential hypertension: a hypothesis.
Topics: Biological Transport; Calcium; Humans; Hydrogen; Hypertension; Models, Biological; Renin; Sodium; So | 1988 |
Relationship of cerebral blood flow and metabolism to neurological symptoms.
Topics: Acetylcholine; Animals; Autoradiography; Blood Flow Velocity; Blood Gas Analysis; Brain; Carbon Diox | 1972 |
Intrarenal distribution of blood flow.
Topics: Acute Kidney Injury; Aminohippuric Acids; Animals; Blood Flow Velocity; Calorimetry; Dogs; Glomerula | 1971 |
1 trial available for hydrogen and Hypertension
| Article | Year |
|---|---|
Spironolactone prevents Na+/H+ exchange enhancement in primary aldosteronism.
Topics: Adult; Blood Pressure; Erythrocytes; Female; Humans; Hydrogen; Hyperaldosteronism; Hypertension; Mal | 1997 |
30 other studies available for hydrogen and Hypertension
| Article | Year |
|---|---|
Effects of hydrogen-rich water and ascorbic acid treatment on spontaneously hypertensive rats.
Topics: Animals; Ascorbic Acid; Hydrogen; Hypertension; Rats; Rats, Inbred SHR; Sodium Chloride; Water | 2022 |
Structural and dynamic investigation of non-synonymous variations in Renin-AGT complex revealed altered binding via hydrogen-bonding network reprogramming to accelerate the hypertension pathway.
Topics: Angiotensinogen; Humans; Hydrogen; Hypertension; Renin; Renin-Angiotensin System | 2022 |
Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension.
Topics: Animals; Blood Pressure; Echocardiography; Gases; Hydrogen; Hypertension; Hypertrophy, Left Ventricu | 2019 |
HV1 acts as a sodium sensor and promotes superoxide production in medullary thick ascending limb of Dahl salt-sensitive rats.
Topics: Animals; Disease Models, Animal; Hydrogen; Hydrogen-Ion Concentration; Hypertension; Ion Channels; K | 2014 |
Hydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats.
Topics: Administration, Oral; Albumins; Animals; Blood Pressure; Blood-Brain Barrier; Body Weight; Cerebral | 2015 |
Chronic hydrogen-rich saline treatment reduces oxidative stress and attenuates left ventricular hypertrophy in spontaneous hypertensive rats.
Topics: Angiotensin II; Animals; Antioxidants; Catalase; Cytokines; Electron Transport Chain Complex Protein | 2012 |
[DETERMINATION OF LEFT-RIGHT SHUNTS BY THE HYDROGEN METHOD].
Topics: Angiocardiography; Cardiac Catheterization; Heart Defects, Congenital; Heart Septal Defects; Humans; | 1964 |
Left ventricular hypertrophy in asymptomatic essential hypertension: its relationship with aldosterone and the increase in sodium-proton exchanger activity.
Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Case-Control Studies; Erythrocytes; Female; Humans; | 1993 |
Magnetization transfer characterization of hypertensive cardiomyopathy: significance of tissue water content.
Topics: Age Factors; Animals; Body Water; Body Weight; Cardiomyopathy, Hypertrophic; Desiccation; Electron S | 1993 |
Platelet Na+/H+ antiport activity in patients with insulin-dependent diabetes mellitus with and without diabetic nephropathy.
Topics: Adult; Blood Platelets; Blood Pressure; Body Mass Index; Carrier Proteins; Diabetes Mellitus, Type 1 | 1993 |
Characteristics of the sodium/hydrogen exchange in non-insulin-dependent diabetic patients with microalbuminuria and hypertension.
Topics: Albuminuria; Blood Platelets; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hyd | 1996 |
Blood flow rate in normal and tumor-bearing rats in conscious state, under urethane anesthesia, and during systemic hypothermia.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Angiotensin II; Animals; Cardiac Output; Ceftazid | 1998 |
In-vivo intracellular pH at rest and during exercise in patients with essential hypertension.
Topics: Exercise; Female; Humans; Hydrogen; Hydrogen-Ion Concentration; Hypertension; Intracellular Membrane | 2001 |
Persistent hypertension does not alter the cerebral blood flow and glucose utilization in young-adult Dahl salt-sensitive rats.
Topics: Animals; Brain; Carbon Radioisotopes; Cerebrovascular Circulation; Deoxyglucose; Diet, Sodium-Restri | 2002 |
Distribution of myocardial blood flow measured by hydrogen polarography.
Topics: Animals; Coronary Circulation; Dogs; Hydrogen; Hyperemia; Hypertension; Vectorcardiography | 1976 |
Increased Na(+)-H+ exchange in jejunal brush border membrane vesicles of spontaneously hypertensive rats.
Topics: Amiloride; Animals; Biological Transport, Active; Carrier Proteins; Hydrogen; Hydrogen-Ion Concentra | 1991 |
Na+/H+ and HCO3-/Cl- exchange in the control of intracellular pH in vivo in the spontaneously hypertensive rat.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo | 1991 |
Erythrocyte Na(+)-H+ exchange activity in a group of essential hypertensive patients.
Topics: Adult; Carrier Proteins; Erythrocyte Membrane; Humans; Hydrogen; Hypertension; Ion Exchange; Middle | 1991 |
Sodium-hydrogen exchange and cardiac hypertrophy in patients with primary hypertension.
Topics: Adult; Cardiomegaly; Carrier Proteins; Female; Humans; Hydrogen; Hypertension; Ion Exchange; Lymphoc | 1991 |
Diabetes mellitus and hypertension: a physiologic basis for a rational therapeutic approach.
Topics: Antihypertensive Agents; Biological Transport; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; | 1991 |
Increased Na(+)-H+ exchange activity in cultured vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats.
Topics: Animals; Cells, Cultured; Cerebrovascular Disorders; Cytoplasm; Fluoresceins; Hydrogen; Hydrogen-Ion | 1990 |
Evidence for abnormal Na+/H+ antiport activity detected by phosphorus nuclear magnetic resonance spectroscopy in exercising skeletal muscle of patients with essential hypertension.
Topics: Biological Transport, Active; Cell Membrane; Cells, Cultured; Female; Forearm; Humans; Hydrogen; Hyd | 1990 |
Platelet cytosolic proton and free calcium concentrations in essential hypertension.
Topics: Adult; Benzofurans; Blood Platelets; Calcium; Cytosol; Female; Fluoresceins; Fura-2; Humans; Hydroge | 1989 |
Nisoldipine inhibition of sodium influx into aorta from aldosterone-salt-hypertensive rats.
Topics: Aldosterone; Animals; Aorta; Calcium; Calcium Channel Blockers; Hydrogen; Hypertension; Ion Exchange | 1989 |
Effect of the calcium antagonists felodipine and nimodipine on cortical blood flow in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cerebral Cortex; Felodipine; Homeostasis; Hydrogen; Hypertension; Male; Nim | 1989 |
Increased platelet Na+-H+ exchange rates in essential hypertension: application of a novel test.
Topics: Blood Platelets; Evaluation Studies as Topic; Female; Humans; Hydrogen; Hypertension; Ion Exchange; | 1987 |
The Na+-H+ antiport in essential hypertension.
Topics: Biological Transport; Blood Platelets; Cations; Erythrocytes; Humans; Hydrogen; Hypertension; Male; | 1987 |
Glimpses of the mechanisms of hypertension.
Topics: Humans; Hydrogen; Hypertension; Sodium | 1986 |
[Characteristics of Na+/H+ metabolism in the erythrocytes of rats with spontaneous hypertension].
Topics: Amiloride; Animals; Erythrocyte Deformability; Erythrocytes; Hydrogen; Hypertension; Male; Potassium | 1987 |
Right atrial admixture in coronary venous blood.
Topics: Animals; Blood Gas Analysis; Cardiac Catheterization; Chromatography, Gas; Coronary Vessels; Deuteri | 1969 |