berberine has been researched along with Hypertension in 12 studies
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Berberine, extracted from Coptis Root and Phellodendron Chinese, has been frequently used for the adjuvant treatment of type 2 diabetes mellitus, hyperlipidemia, and hypertension in China." | 8.91 | Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension. ( Dong, F; Fan, J; Lan, J; Sun, G; Yan, Z; Zhao, Y; Zheng, W, 2015) |
| "Hypertension is the highest risk factor for disease globally." | 6.72 | Berberine for the treatment of hypertension: A systematic review. ( Atherton, I; Suadoni, MT, 2021) |
| "Berberine, extracted from Coptis Root and Phellodendron Chinese, has been frequently used for the adjuvant treatment of type 2 diabetes mellitus, hyperlipidemia, and hypertension in China." | 4.91 | Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension. ( Dong, F; Fan, J; Lan, J; Sun, G; Yan, Z; Zhao, Y; Zheng, W, 2015) |
| "The current study investigated the mechanism underlying the therapeutic effects of berberine in the vasculature in hypertension." | 4.02 | Berberine ameliorates vascular dysfunction by a global modulation of lncRNA and mRNA expression profiles in hypertensive mouse aortae. ( Han, W; Li, L; Liu, L; Tan, N; Zhang, Y; Zong, Y, 2021) |
| "Berberine could delay the onset and attenuate the severity of hypertension, as well as ameliorate hypertension-induced renal damage in SHR rats." | 3.81 | Anti-hypertensive and renoprotective effects of berberine in spontaneously hypertensive rats. ( Guo, Z; Sun, H; Zhang, H; Zhang, Y, 2015) |
| "Berberine, as an alkaloid found in many Chinese herbs, improves vascular functions in patients with cardiovascular diseases." | 3.81 | Berberine via suppression of transient receptor potential vanilloid 4 channel improves vascular stiffness in mice. ( Guo, T; Peng, QS; Wang, J; Wang, SX; Yue, SW, 2015) |
| "Hypertension is the highest risk factor for disease globally." | 2.72 | Berberine for the treatment of hypertension: A systematic review. ( Atherton, I; Suadoni, MT, 2021) |
| "Berberine has several preventive effects on cardiovascular diseases." | 1.46 | Berberine promotes ischemia-induced angiogenesis in mice heart via upregulation of microRNA-29b. ( Jian, X; Li, P; Ping, S; Wan, GR; Yin, YL; Yu, HY; Zhu, ML, 2017) |
| "Treated with berberine for 4 weeks, elevated blood pressure and heightened levels of urine protein, blood urea nitrogen and serum creatinine in model rats were depressed significantly (P < 0." | 1.37 | [Effects and mechanism of berberine on the hypertensive renal injury rats induced by enriched high fat-salt-fructose diet]. ( Cai, Y; Li, HB; Lv, JH; Qi, CL, 2011) |
| "Berberine is a natural isoquinoline alkaloid found in plants of the Ranunculaceae and Berberidaceae families." | 1.30 | The antihypertensive effect of the berberine derivative 6-protoberberine in spontaneously hypertensive rats. ( Chan, P; Chen, YJ; Cheng, JT; Hong, SH; Liu, JC; Tomlinson, B, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Suadoni, MT | 1 |
| Atherton, I | 1 |
| Tan, N | 1 |
| Zhang, Y | 3 |
| Li, L | 1 |
| Zong, Y | 1 |
| Han, W | 1 |
| Liu, L | 2 |
| Zhu, ML | 1 |
| Yin, YL | 1 |
| Ping, S | 1 |
| Yu, HY | 1 |
| Wan, GR | 1 |
| Jian, X | 1 |
| Li, P | 1 |
| Tian, H | 1 |
| Kang, YM | 1 |
| Gao, HL | 1 |
| Shi, XL | 1 |
| Fu, LY | 1 |
| Li, Y | 1 |
| Jia, XY | 1 |
| Liu, KL | 1 |
| Qi, J | 1 |
| Li, HB | 2 |
| Chen, YM | 1 |
| Chen, WS | 1 |
| Cui, W | 1 |
| Zhu, GQ | 1 |
| Yu, XJ | 1 |
| Lan, J | 1 |
| Zhao, Y | 1 |
| Dong, F | 1 |
| Yan, Z | 1 |
| Zheng, W | 1 |
| Fan, J | 1 |
| Sun, G | 1 |
| Liu, J | 1 |
| Huang, Z | 1 |
| Yu, X | 1 |
| Zhang, X | 1 |
| Dou, D | 1 |
| Huang, Y | 1 |
| Guo, Z | 1 |
| Sun, H | 1 |
| Zhang, H | 1 |
| Wang, J | 1 |
| Guo, T | 1 |
| Peng, QS | 1 |
| Yue, SW | 1 |
| Wang, SX | 1 |
| Mazza, A | 1 |
| Lenti, S | 1 |
| Schiavon, L | 1 |
| Zuin, M | 1 |
| D'Avino, M | 1 |
| Ramazzina, E | 1 |
| Casiglia, E | 1 |
| Cai, Y | 1 |
| Qi, CL | 1 |
| Lv, JH | 1 |
| FACQUET, J | 1 |
| Liu, JC | 1 |
| Chan, P | 1 |
| Chen, YJ | 1 |
| Tomlinson, B | 1 |
| Hong, SH | 1 |
| Cheng, JT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Berberine on Cardiovascular Disease Risk Factors: a Mechanistic Randomized Controlled Trial[NCT03770325] | Phase 2/Phase 3 | 84 participants (Actual) | Interventional | 2019-04-01 | Completed | ||
| A Single-center, Randomized, Open-label, Controlled, Dose-escalating, Parallel-group Study to Assess the Anti-platelet Effect of Berberine in Patients Receiving Aspirin and Clopidogrel After Percutaneous Coronary Intervention[NCT03378934] | Phase 4 | 64 participants (Anticipated) | Interventional | 2018-09-26 | Recruiting | ||
| A Double-blind, Randomized, Placebo-controlled Trial of Berberine as an Adjuvant to Treat Antipsychotic-induced Metabolic Syndrome in Patients With Schizophrenia Spectrum Disorders[NCT02983188] | Phase 2/Phase 3 | 113 participants (Actual) | Interventional | 2018-04-25 | Completed | ||
| The Effect of Berberine on the Secretion of Incretin in Normal Man[NCT05947370] | Early Phase 1 | 16 participants (Actual) | Interventional | 2022-10-12 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for berberine and Hypertension
| Article | Year |
|---|---|
Berberine for the treatment of hypertension: A systematic review.
Topics: Antihypertensive Agents; Berberine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; H | 2021 |
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Topics: Antihypertensive Agents; Berberine; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension | 2015 |
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Topics: Antihypertensive Agents; Berberine; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension | 2015 |
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Topics: Antihypertensive Agents; Berberine; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension | 2015 |
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Topics: Antihypertensive Agents; Berberine; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension | 2015 |
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Topics: Antihypertensive Agents; Berberine; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension | 2015 |
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Topics: Antihypertensive Agents; Berberine; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension | 2015 |
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Topics: Antihypertensive Agents; Berberine; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension | 2015 |
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Topics: Antihypertensive Agents; Berberine; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension | 2015 |
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Topics: Antihypertensive Agents; Berberine; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension | 2015 |
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Topics: Antihypertensive Agents; Berberine; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension | 2015 |
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Topics: Antihypertensive Agents; Berberine; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension | 2015 |
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Topics: Antihypertensive Agents; Berberine; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension | 2015 |
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Topics: Antihypertensive Agents; Berberine; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension | 2015 |
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Topics: Antihypertensive Agents; Berberine; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension | 2015 |
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Topics: Antihypertensive Agents; Berberine; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension | 2015 |
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Topics: Antihypertensive Agents; Berberine; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension | 2015 |
1 trial available for berberine and Hypertension
| Article | Year |
|---|---|
Nutraceuticals for Serum Lipid and Blood Pressure Control in Hypertensive and Hypercholesterolemic Subjects at Low Cardiovascular Risk.
Topics: Berberine; Biological Products; Blood Pressure; Cardiovascular Diseases; Diet; Dietary Supplements; | 2015 |
9 other studies available for berberine and Hypertension
| Article | Year |
|---|---|
Berberine ameliorates vascular dysfunction by a global modulation of lncRNA and mRNA expression profiles in hypertensive mouse aortae.
Topics: Angiotensin II; Animals; Aorta; Berberine; Blood Pressure; Gene Expression Profiling; Hypertension; | 2021 |
Berberine promotes ischemia-induced angiogenesis in mice heart via upregulation of microRNA-29b.
Topics: AMP-Activated Protein Kinases; Angiogenesis Inducing Agents; Animals; Berberine; Cell Proliferation; | 2017 |
Chronic infusion of berberine into the hypothalamic paraventricular nucleus attenuates hypertension and sympathoexcitation via the ROS/Erk1/2/iNOS pathway.
Topics: Animals; Arterial Pressure; Berberine; Hypertension; Male; MAP Kinase Signaling System; NADPH Oxidas | 2019 |
Berberine improves endothelial function by inhibiting endoplasmic reticulum stress in the carotid arteries of spontaneously hypertensive rats.
Topics: AMP-Activated Protein Kinases; Animals; Berberine; Carotid Arteries; Cyclooxygenase 2; Endoplasmic R | 2015 |
Anti-hypertensive and renoprotective effects of berberine in spontaneously hypertensive rats.
Topics: Animals; Berberine; Blood Pressure; Disease Models, Animal; Glomerular Filtration Rate; Hypertension | 2015 |
Berberine via suppression of transient receptor potential vanilloid 4 channel improves vascular stiffness in mice.
Topics: Aging; Animals; Berberine; Blood Pressure; Cardiovascular Diseases; Hypertension; Mice; Organ Cultur | 2015 |
[Effects and mechanism of berberine on the hypertensive renal injury rats induced by enriched high fat-salt-fructose diet].
Topics: Animals; Berberine; Blood Pressure; Body Weight; Creatinine; Diet; Diet, High-Fat; Disease Models, A | 2011 |
[The action of tetrahydroberberine HC1 on arterial hypertension].
Topics: Alkaloids; Berberine; Hypertension | 1954 |
The antihypertensive effect of the berberine derivative 6-protoberberine in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Berberine; Blood Pressure; Cardiac Output; Central Nervous System; | 1999 |