Page last updated: 2024-10-30

methadone and Hypertension

methadone has been researched along with Hypertension in 12 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"Risk factors in older methadone maintenance treatment (MMT) patients may put them at a greater risk of acquiring chronic diseases; however, this group might experience barriers to treatment resulting in reduced recommended prescriptions."7.79Hypertension, chronic obstructive pulmonary disease, diabetes and depression among older methadone maintenance patients in British Columbia. ( Borycki, E; Macdonald, S; Maruyama, A; Zhao, J, 2013)
"Risk factors in older methadone maintenance treatment (MMT) patients may put them at a greater risk of acquiring chronic diseases; however, this group might experience barriers to treatment resulting in reduced recommended prescriptions."3.79Hypertension, chronic obstructive pulmonary disease, diabetes and depression among older methadone maintenance patients in British Columbia. ( Borycki, E; Macdonald, S; Maruyama, A; Zhao, J, 2013)
"Illicit drugs such as cocaine, and methadone can induce acquired long QT syndrome."3.77Cardiovascular-associated disease in an addicted population: an observation study. ( Bignamini, E; Cappa, C; Compostino, R; De Vivo, E; Demarie, D; Ferro, S; Imazio, M; Marletta, G; Trinchero, R, 2011)
"Most methadone treatment programs have insufficient resources to provide medical care."2.67Providing medical care to methadone clinic patients: referral vs on-site care. ( Bigelow, GE; Ginn, DH; Pabst, KM; Umbricht-Schneiter, A, 1994)
"Commonly diagnosed conditions included drug abuse, psychiatric disorder, trauma, and alcohol abuse."1.26Health status of the New York City prison population. ( Loewenstein, R; Novick, LF; Penna, RD; Remmlinger, E; Schwartz, MS, 1977)
"Hypertension was present in 2."1.25Prevalence of renal disease in asymptomatic heroin addicts. ( Arruda, JA; Kurtzman, NA; Pillay, VK, 1975)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's3 (25.00)18.2507
2000's2 (16.67)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maruyama, A1
Macdonald, S1
Borycki, E1
Zhao, J1
Müller, MC1
Pichler, M1
Martin, G1
Plörer, D1
Winter, C1
Pogarell, O1
Bogner, JR1
Demarie, D1
Marletta, G1
Imazio, M1
Cappa, C1
Ferro, S1
Compostino, R1
De Vivo, E1
Trinchero, R1
Bignamini, E1
Friedman, R1
Kamel, I1
Perez, C1
Hamada, A1
SALTER, WT1
Dube, SK1
Jhaveri, RC1
Rosenfeld, W1
Evans, HE1
Khan, F1
Spergel, G1
Umbricht-Schneiter, A1
Ginn, DH1
Pabst, KM1
Bigelow, GE1
Lynn, KL1
Pickering, W1
Gardner, J1
Bailey, RR1
Robson, RA1
Novick, LF1
Penna, RD1
Schwartz, MS1
Remmlinger, E1
Loewenstein, R1
Blackett, PR1
Pascarelli, EF1
Arruda, JA1
Kurtzman, NA1
Pillay, VK1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care[NCT01621711]504 participants (Actual)Interventional2011-03-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for methadone and Hypertension

ArticleYear
Providing medical care to methadone clinic patients: referral vs on-site care.
    American journal of public health, 1994, Volume: 84, Issue:2

    Topics: Female; Health Services; HIV Infections; Humans; Hypertension; Male; Methadone; Referral and Consult

1994

Other Studies

11 other studies available for methadone and Hypertension

ArticleYear
Hypertension, chronic obstructive pulmonary disease, diabetes and depression among older methadone maintenance patients in British Columbia.
    Drug and alcohol review, 2013, Volume: 32, Issue:4

    Topics: British Columbia; Case-Control Studies; Chronic Disease; Depression; Diabetes Mellitus; Drug Utiliza

2013
[Burden of disease and level of patient's medical care in substitution treatment for opiates].
    Medizinische Klinik (Munich, Germany : 1983), 2009, Dec-15, Volume: 104, Issue:12

    Topics: Adult; Asthma; Comorbidity; Cooperative Behavior; Cost of Illness; Cross-Sectional Studies; Female;

2009
Cardiovascular-associated disease in an addicted population: an observation study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2011, Volume: 12, Issue:1

    Topics: Adult; Buprenorphine; Cardiovascular Diseases; Electrocardiography; Female; Humans; Hypertension; Lo

2011
Severe intraoperative hypertension and opioid-resistant postoperative pain in a methadone-treated patient.
    The journal of pain, 2003, Volume: 4, Issue:5

    Topics: Adult; Analgesics, Opioid; Drug Resistance; Female; Hemodynamics; Humans; Hypertension; Intraoperati

2003
Therapeutics and toxicology.
    Annual review of medicine, 1950, Volume: 1

    Topics: Anemia; Anemia, Pernicious; Antacids; Anti-Bacterial Agents; Arthritis; Arthritis, Rheumatoid; Blood

1950
Urinary catecholamines, plasma renin activity and blood pressure in newborns: effects of narcotic withdrawal.
    Developmental pharmacology and therapeutics, 1981, Volume: 3, Issue:2

    Topics: Catecholamines; Diastole; Female; Heroin; Humans; Hypertension; Infant, Newborn; Infant, Newborn, Di

1981
Intravenous drug use and glomerular deposition of lipid-like material.
    Nephron, 1998, Volume: 80, Issue:3

    Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Eosinophils; Female; Glomerular Mesangium; Hepatitis

1998
Experts clarify issues raised by combination therapy.
    AIDS alert, 1998, Volume: 13, Issue:5

    Topics: Adipose Tissue; Alcoholism; Drug Interactions; Drug Therapy, Combination; Guidelines as Topic; HIV I

1998
Health status of the New York City prison population.
    Medical care, 1977, Volume: 15, Issue:3

    Topics: Adult; Alcoholism; Asthma; Demography; Educational Status; Epilepsy; Female; Hepatitis; Heroin Depen

1977
Transient hypertension. Associated with methadone intoxication.
    New York state journal of medicine, 1976, Volume: 76, Issue:12

    Topics: Child, Preschool; Humans; Hypertension; Male; Methadone

1976
Prevalence of renal disease in asymptomatic heroin addicts.
    Archives of internal medicine, 1975, Volume: 135, Issue:4

    Topics: Chicago; Creatine; Evaluation Studies as Topic; Heroin Dependence; Humans; Hypertension; Inactivatio

1975