fluconazole has been researched along with Hypertension in 5 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We sought to clarify, using functional and biological approaches, the role of epoxyeicosatrienoic acids, nitric oxide (NO)/reactive oxygen species balance, and endothelin-1 in conduit artery endothelial dysfunction during essential hypertension." | 9.16 | Epoxyeicosatrienoic acids contribute with altered nitric oxide and endothelin-1 pathways to conduit artery endothelial dysfunction in essential hypertension. ( Bellien, J; Dreano, Y; Gutierrez, L; Iacob, M; Joannides, R; Lucas, D; Mercier, A; Monteil, C; Remy-Jouet, I; Thuillez, C; Vendeville, C, 2012) |
| "We sought to clarify, using functional and biological approaches, the role of epoxyeicosatrienoic acids, nitric oxide (NO)/reactive oxygen species balance, and endothelin-1 in conduit artery endothelial dysfunction during essential hypertension." | 5.16 | Epoxyeicosatrienoic acids contribute with altered nitric oxide and endothelin-1 pathways to conduit artery endothelial dysfunction in essential hypertension. ( Bellien, J; Dreano, Y; Gutierrez, L; Iacob, M; Joannides, R; Lucas, D; Mercier, A; Monteil, C; Remy-Jouet, I; Thuillez, C; Vendeville, C, 2012) |
| "Arterial hypertension was induced in FVB/N mice by renal artery stenosis ('two-kidney-one-clip', 2K1C)." | 1.37 | Soluble epoxide hydrolase inhibition prevents coronary endothelial dysfunction in mice with renovascular hypertension. ( Bellien, J; Bounoure, F; Dautreaux, B; Gao, J; Gomez, E; Henry, JP; Richard, V; Skiba, M; Thuillez, C, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellien, J | 4 |
| Favre, J | 1 |
| Iacob, M | 3 |
| Gao, J | 2 |
| Thuillez, C | 4 |
| Richard, V | 2 |
| Joannidès, R | 3 |
| Gomez, E | 1 |
| Henry, JP | 1 |
| Dautreaux, B | 1 |
| Bounoure, F | 1 |
| Skiba, M | 1 |
| Remy-Jouet, I | 2 |
| Lucas, D | 2 |
| Monteil, C | 1 |
| Gutierrez, L | 2 |
| Vendeville, C | 1 |
| Dreano, Y | 2 |
| Mercier, A | 2 |
| Godoy, JS | 1 |
| de Souza Bonfim-Mendonça, P | 1 |
| Nakamura, SS | 1 |
| Yamada, SS | 1 |
| Shinobu-Mesquita, C | 1 |
| Pieralisi, N | 1 |
| Fiorini, A | 1 |
| Svidzinski, TI | 1 |
| Blot, E | 1 |
| Donnadieu, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Pharmacological Heart Rate Reduction on Visco-elastic Properties of the Arterial Wall (BRADYVASC)[NCT02584439] | Phase 3 | 30 participants (Anticipated) | Interventional | 2015-10-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for fluconazole and Hypertension
| Article | Year |
|---|---|
Arterial stiffness is regulated by nitric oxide and endothelium-derived hyperpolarizing factor during changes in blood flow in humans.
Topics: Adult; Animals; Benzimidazoles; Biological Factors; Blood Pressure; Elasticity; Endothelium, Vascula | 2010 |
Epoxyeicosatrienoic acids contribute with altered nitric oxide and endothelin-1 pathways to conduit artery endothelial dysfunction in essential hypertension.
Topics: 14-alpha Demethylase Inhibitors; Adult; Eicosanoids; Endothelin-1; Endothelium, Vascular; Enzyme Inh | 2012 |
3 other studies available for fluconazole and Hypertension
| Article | Year |
|---|---|
Soluble epoxide hydrolase inhibition prevents coronary endothelial dysfunction in mice with renovascular hypertension.
Topics: Amides; Animals; Blotting, Western; Coronary Vessels; Echocardiography; Endothelium, Vascular; Enzym | 2011 |
Colonization of the oral cavity by yeasts in patients with chronic renal failure undergoing hemodialysis.
Topics: Adult; Aged; Aged, 80 and over; Amphotericin B; Antifungal Agents; Candida; Candida albicans; Candid | 2013 |
Impaired role of epoxyeicosatrienoic acids in the regulation of basal conduit artery diameter during essential hypertension.
Topics: Adult; Blood Pressure; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 | 2012 |