Compounds > 1-cyclohexyl-3-dodecylurea
Page last updated: 2024-12-10

1-cyclohexyl-3-dodecylurea

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

1-cyclohexyl-3-dodecylurea is a **synthetic compound**, specifically a **urea derivative**. It's a relatively **uncommon** molecule, and its importance for research is not widely documented. Therefore, it's difficult to give a definitive answer to its significance without more context.

**However, based on its structure and properties, we can speculate on potential research areas where it might be relevant:**

* **Surfactant Chemistry:** The presence of a long hydrocarbon chain (dodecyl) and a polar urea group suggests 1-cyclohexyl-3-dodecylurea could exhibit surfactant properties. This could be relevant in fields like:
* **Colloid Science:** Studying the formation of micelles, emulsions, and other colloidal systems.
* **Detergent development:** Investigating its potential as a cleaning agent.
* **Materials Science:** The combination of hydrophobic and hydrophilic elements could lead to interesting applications in materials design, such as:
* **Self-assembly:** Investigating the formation of ordered structures like supramolecular polymers or nanomaterials.
* **Coatings:** Exploring its use as a surface modifier for various applications.
* **Drug Delivery:** The lipophilic nature of the dodecyl chain might make it useful in the design of drug delivery systems, particularly those targeting hydrophobic drug molecules.

**To understand the specific importance of 1-cyclohexyl-3-dodecylurea in research, it's crucial to consider:**

* **The specific research question or area of study:** What is the research goal? What is the expected outcome?
* **The experimental context:** What specific experiments are being performed? What are the conditions and parameters used?
* **The literature:** Has this compound been studied before? What are the published findings?

**In summary, while 1-cyclohexyl-3-dodecylurea's specific research significance is unclear without further information, its chemical structure and properties suggest potential relevance in areas like surfactant chemistry, materials science, and drug delivery.**

Cross-References

ID SourceID
PubMed CID4437430
CHEMBL ID3661355
SCHEMBL ID652844
MeSH IDM0418397

Synonyms (19)

Synonym
1-cyclohexyl-3-dodecylurea
STK447469
AKOS003254832
402939-18-8
urea, n-cyclohexyl-n'-dodecyl-
SCHEMBL652844
bdbm129261
us8815951, 297
n-cyclohexyl-n'-dodecylurea
1-cyclohexyl-3-dodecyl urea
DTXSID90403288
CHEMBL3661355
HY-135795
ncnd
cdu;n-cyclohexyl-n-dodecyl urea;ncnd
CS-0114069
MS-24526
cdu, n-cyclohexyl-n'-dodecylurea, 1-cyclohexyl-3'-dodecylurea
1-cyclohexyl-3'-dodecylurea

Research Excerpts

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (85.71)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.28

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.28 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.36 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.28)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
urea
pseudourea: clinical use; structure. isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.		8.4170isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
clofibrate
angiokapsul: contains clofibrate & insoitolnicotinate		2.0110aromatic ether;
ethyl ester;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
geroprotector;
PPARalpha agonist
glyburide
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide. glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.		2.0510monochlorobenzenes;
N-sulfonylurea		anti-arrhythmia drug;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor;
hypoglycemic agent
1,3-dicyclohexylurea
1,3-dicyclohexylurea: degradation product of 1-(2-chloroethyl)-3- cyclohexyl-1-nitrosourea; structure		210ureas
thymidine
[no description available]		2.0110pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
carbachol
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.		2.0510ammonium salt;
carbamate ester		cardiotonic drug;
miotic;
muscarinic agonist;
nicotinic acetylcholine receptor agonist;
non-narcotic analgesic
adamantane
Adamantane: A tricyclo bridged hydrocarbon.		210adamantanes;
polycyclic alkane
angiotensin ii
Giapreza: injectable form of angiotensin II used to increase blood pressure in adult patients with septic or other distributive shock. Ile(5)-angiotensin II : An angiotensin II that acts on the central nervous system (PDB entry: 1N9V).		2.0210amino acid zwitterion;
angiotensin II		human metabolite
arachidonic acid
icosa-5,8,11,14-tetraenoic acid : Any icosatetraenoic acid with the double bonds at positions 5, 8, 11 and 14.. arachidonate : A long-chain fatty acid anion resulting from the removal of a proton from the carboxy group of arachidonic acid.		2.4420icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid		Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite
n-hydroxy-n'-(4-butyl-2-methylphenyl)formamidine
HET0016: 20-Hydroxyeicosatetraenoic Acid synthesis inhibitor		2.4620toluenes
linoleic acid
Linoleic Acid: A doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed). linoleic acid : An octadecadienoic acid in which the two double bonds are at positions 9 and 12 and have Z (cis) stereochemistry.		2.0210octadecadienoic acid;
omega-6 fatty acid		algal metabolite;
Daphnia galeata metabolite;
plant metabolite
8,11,14-eicosatrienoic acid
8,11,14-Eicosatrienoic Acid: A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5.. all-cis-icosa-8,11,14-trienoic acid : An icosatrienoic acid having three cis double bonds at positions 8, 11 and 14.		2.0510fatty acid 20:3;
long-chain fatty acid		fungal metabolite;
human metabolite;
nutraceutical
20-hydroxy-5,8,11,14-eicosatetraenoic acid
20-hydroxy-5,8,11,14-eicosatetraenoic acid: stimulator of renal sodium, potassium atpase; RN given is for the (all-Z) isomer. 20-HETE : A HETE that consists of arachidonic acid bearing a hydroxy substituent at position 20.		2.4620HETE;
hydroxy monocarboxylic acid		human metabolite;
mouse metabolite
nad
NAD(1-) : An anionic form of nicotinamide adenine dinucleotide arising from deprotonation of the two OH groups of the diphosphate moiety.		2.0110organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.		02.0510
Left Ventricular Dysfunction
[description not available]		02.0510
Alloxan Diabetes
[description not available]		02.0510
Injury, Ischemia-Reperfusion
[description not available]		02.0510
Reperfusion Injury
Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.		02.0510
Ventricular Dysfunction, Left
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.		02.0510
Blood Pressure, High
[description not available]		02.0510
Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.		02.0510
Vascular Diseases
Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.		02.0510
Hypertension, Renal
Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.		02.0210