ns 1619 has been researched along with Hypertension in 2 studies
NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellien, J | 1 |
| Favre, J | 1 |
| Iacob, M | 1 |
| Gao, J | 1 |
| Thuillez, C | 1 |
| Richard, V | 1 |
| Joannidès, R | 1 |
| Bratz, IN | 1 |
| Falcon, R | 1 |
| Partridge, LD | 1 |
| Kanagy, NL | 1 |
1 trial available for ns 1619 and Hypertension
| Article | Year |
|---|---|
Arterial stiffness is regulated by nitric oxide and endothelium-derived hyperpolarizing factor during changes in blood flow in humans.
Topics: Adult; Animals; Benzimidazoles; Biological Factors; Blood Pressure; Elasticity; Endothelium, Vascula | 2010 |
1 other study available for ns 1619 and Hypertension
| Article | Year |
|---|---|
Vascular smooth muscle cell membrane depolarization after NOS inhibition hypertension.
Topics: Animals; Arginine; Benzimidazoles; Calcium; Cell Membrane; Endothelium, Vascular; Enzyme Inhibitors; | 2002 |