hexamethonium has been researched along with Hypertension in 275 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Excerpt | Relevance | Reference |
---|---|---|
"This study aimed to evaluate whether exercise training could contribute to a better modulation of the neurohumoral mechanisms linked to the pathophysiology of arterial hypertension (AH) in postmenopausal hypertensive rats treated with hydrochlorothiazide (HCTZ)." | 8.31 | Concurrent exercise training induces additional benefits to hydrochlorothiazide: Evidence for an improvement of autonomic control and oxidative stress in a model of hypertension and postmenopause. ( Bernardes, N; da Silva Dias, D; De Angelis, K; Ferreira, MJ; Irigoyen, MC; Santos Ferreira Silva, MPD, 2023) |
"Many studies have implicated both angiotensin II (ANG II) and aldosterone (Aldo) in the pathogenesis of hypertension, the progression of renal injury, and cardiac remodeling after myocardial infarction." | 7.77 | Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension. ( Beltz, TG; Gomez-Sanchez, CE; Guo, F; Hay, M; Johnson, AK; Xue, B; Yu, Y, 2011) |
"This study was conducted to examine if central amiloride-sensitive transport systems are involved in the development and/or maintenance of hypertension in spontaneously hypertensive rats (SHR)." | 7.71 | Contribution of central amiloride-sensitive transport systems to the development of hypertension in spontaneously hypertensive rats. ( Akahoshi, M; Kitamura, S; Nagao, S; Nonaka, M; Seto, S; Yano, K, 2001) |
"To explore the pathophysiological role of leptin in obesity-related hypertension, we examined cardiovascular phenotypes of transgenic skinny mice whose elevated plasma leptin concentrations are comparable to those seen in obese subjects." | 7.70 | Pathophysiological role of leptin in obesity-related hypertension. ( Aizawa-Abe, M; Ebihara, K; Hayashi, T; Hosoda, K; Inoue, G; Iwai, H; Masuzaki, H; Matsuoka, N; Nakao, K; Ogawa, Y; Satoh, N; Yoshimasa, Y, 2000) |
"The purpose of the present study was to identify mechanisms that contribute to increased venous smooth muscle tone in desoxycorticosterone acetate (DOCA)-salt hypertension in rats." | 7.70 | Mechanisms of increased venous smooth muscle tone in desoxycorticosterone acetate-salt hypertension. ( Fink, GD; Galligan, JJ; Johnson, RJ, 2000) |
" To investigate the mechanisms by which bupivacaine may act within the CNS to produce cardiovascular toxicity, we studied four groups of halothane-anesthetized rabbits in which infusion of intracerebroventricular (icv) bupivacaine or intravenous (iv) phenylephrine resulted in dysrhythmias and hypertension." | 7.68 | Hexamethonium and midazolam terminate dysrhythmias and hypertension caused by intracerebroventricular bupivacaine in rabbits. ( Artu, AA; Bernards, CM, 1991) |
"The objective of this study was to determine if ablation of the lateral parabrachial nucleus (LPBN) would prevent angiotensin II-induced hypertension in rats." | 7.68 | Lateral parabrachial nucleus and angiotensin II-induced hypertension. ( Fink, GD; Haywood, JR; Ohman, LE; Pawloski, CM, 1991) |
"Twenty-one patients have been treated for hypertension with oral doses of hexamethonium salts, Apresoline(R) or combinations of both." | 7.63 | Hexamethonium and hydralazine hydrochloride for treatment of hypertension. ( STUPPY, LJ, 1954) |
"When hexamethonium was used to assess autonomic control of MAP, no differences in the decrease of MAP in response to ganglionic blockade were detected during the induction." | 5.40 | CNS neuroplasticity and salt-sensitive hypertension induced by prior treatment with subpressor doses of ANG II or aldosterone. ( Beltz, T; Clayton, SC; Johnson, AK; Xue, B; Zhang, Z, 2014) |
"Nicotine (200 mg/kg) was administered as a single bolus, as infusions lasting 7." | 5.30 | Tachyphylaxis and sensitization to nicotine-induced tachycardiac and pressor effects after nicotine infusions. ( Cruz, SL; Vidrio, H, 1997) |
"Pretreatment with prazosin (0." | 5.28 | Quipazine-induced hypertension in anaesthetized cats is mediated by central and peripheral 5-HT2 receptors: role of the ventrolateral pressor area. ( Bouysset, F; Laubie, M; Schmitt, H; Vayssettes-Courchay, C; Verbeuren, TJ, 1991) |
"Hexamethonium is a potent anti-hypertensive agent." | 5.23 | Use of hexamethonium in arterial hypertension. ( RYTAND, DA, 1954) |
" Some of this information includes: the unexpected yet very real hazards as well as benefits associated with the long-term use of powerful drugs, in particular the original description of hydralazine-induced lupus, its relation to genetic markers and its association with control of hypertension; the apparently decreasing need for antihypertensive drugs in subjects with well-controlled severe and moderate hypertension; the identification of risk factors for the complications of hypertension and the quantitation of their effects; the decrease in the incidence of hypertensive complications associated with the pharmacologic treatment of severe, moderate and, at least, the upper ranges of mild hypertension; the possibility of designing a chemical to block a specific reaction and the realization that it would have broader than expected effects; and the primary prevention of myocardial infarction in very high risk subjects." | 4.77 | The evolution of antihypertensive therapy. ( Perry, HM, 1985) |
"This study aimed to evaluate whether exercise training could contribute to a better modulation of the neurohumoral mechanisms linked to the pathophysiology of arterial hypertension (AH) in postmenopausal hypertensive rats treated with hydrochlorothiazide (HCTZ)." | 4.31 | Concurrent exercise training induces additional benefits to hydrochlorothiazide: Evidence for an improvement of autonomic control and oxidative stress in a model of hypertension and postmenopause. ( Bernardes, N; da Silva Dias, D; De Angelis, K; Ferreira, MJ; Irigoyen, MC; Santos Ferreira Silva, MPD, 2023) |
"Lead is considered a causative factor for hypertension and other cardiovascular diseases." | 3.85 | Sub-chronic lead exposure produces β ( Alonso, MJ; Fioresi, M; Salaices, M; Simões, MR; Toscano, CM; Vassallo, DV, 2017) |
"Early hexamethonium treatment attenuates acute excessive release of catecholamines to prevent cardiac dysfunction and pulmonary edema for increasing survival rate." | 3.79 | Hexamethonium reverses the lethal cardiopulmonary damages in a rat model of brainstem lesions mimicking fatal enterovirus 71 encephalitis. ( Ger, LP; Ho, WY; Hsiao, M; Hsieh, KS; Lai, CC; Lu, PJ; Lu, WH; Tseng, CJ; Wang, JS; Wu, YS, 2013) |
"Many studies have implicated both angiotensin II (ANG II) and aldosterone (Aldo) in the pathogenesis of hypertension, the progression of renal injury, and cardiac remodeling after myocardial infarction." | 3.77 | Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension. ( Beltz, TG; Gomez-Sanchez, CE; Guo, F; Hay, M; Johnson, AK; Xue, B; Yu, Y, 2011) |
"This study was conducted to examine if central amiloride-sensitive transport systems are involved in the development and/or maintenance of hypertension in spontaneously hypertensive rats (SHR)." | 3.71 | Contribution of central amiloride-sensitive transport systems to the development of hypertension in spontaneously hypertensive rats. ( Akahoshi, M; Kitamura, S; Nagao, S; Nonaka, M; Seto, S; Yano, K, 2001) |
"Because the ET(B) receptor is important in venoconstriction, we examined the effects of a selective ET(B) receptor antagonist (A-1 92621) and a mixed ET(A/B) receptor antagonist (A-182086) on endogenous endothelin-1 (ET-1) contributions to elevated venomotor tone in deoxycorticosterone acetate-salt (DOCA-salt) hypertension." | 3.71 | Effect of an ET(B)-selective and a mixed ET(A/B) endothelin receptor antagonist on venomotor tone in deoxycorticosterone-salt hypertension. ( Fink, GD; Galligan, JJ; Johnson, RJ, 2001) |
"To explore the pathophysiological role of leptin in obesity-related hypertension, we examined cardiovascular phenotypes of transgenic skinny mice whose elevated plasma leptin concentrations are comparable to those seen in obese subjects." | 3.70 | Pathophysiological role of leptin in obesity-related hypertension. ( Aizawa-Abe, M; Ebihara, K; Hayashi, T; Hosoda, K; Inoue, G; Iwai, H; Masuzaki, H; Matsuoka, N; Nakao, K; Ogawa, Y; Satoh, N; Yoshimasa, Y, 2000) |
"The purpose of the present study was to identify mechanisms that contribute to increased venous smooth muscle tone in desoxycorticosterone acetate (DOCA)-salt hypertension in rats." | 3.70 | Mechanisms of increased venous smooth muscle tone in desoxycorticosterone acetate-salt hypertension. ( Fink, GD; Galligan, JJ; Johnson, RJ, 2000) |
"After saline pretreatment, response to 5-HT consisted of immediate and brief apnea, bradycardia, and hypotension, followed by sustained tachypnea, tachycardia, pulmonary hypertension, and hypocapnic hypoxemia." | 3.69 | Parasympathetic component of 5-hydroxytryptamine-induced pulmonary dysfunctions in healthy calves. ( Amory, H; Desmecht, DJ; Lekeux, PM; Linden, AS, 1996) |
"We examined the effect of pioglitazone, a thiazolidinedione derivative that increases insulin sensitivity without increasing insulin secretion, on the development and maintenance of hypertension in sucrose-fed SHR." | 3.69 | Reduction of insulin resistance attenuates the development of hypertension in sucrose-fed SHR. ( Fujita, H; Hatta, T; Itoh, H; Kawa, T; Kiyama, M; Miki, S; Moriguchi, J; Morimoto, S; Nakagawa, M; Nakamura, K; Nakata, T; Sasaki, S; Takeda, K; Uchida, A, 1997) |
" To investigate the mechanisms by which bupivacaine may act within the CNS to produce cardiovascular toxicity, we studied four groups of halothane-anesthetized rabbits in which infusion of intracerebroventricular (icv) bupivacaine or intravenous (iv) phenylephrine resulted in dysrhythmias and hypertension." | 3.68 | Hexamethonium and midazolam terminate dysrhythmias and hypertension caused by intracerebroventricular bupivacaine in rabbits. ( Artu, AA; Bernards, CM, 1991) |
"The objective of this study was to determine if ablation of the lateral parabrachial nucleus (LPBN) would prevent angiotensin II-induced hypertension in rats." | 3.68 | Lateral parabrachial nucleus and angiotensin II-induced hypertension. ( Fink, GD; Haywood, JR; Ohman, LE; Pawloski, CM, 1991) |
"To elucidate the role of the dopaminergic system in the maintenance of hypertension in the deoxycorticosterone acetate (DOCA)/NaCl hypertensive rat, the responses of mean arterial pressure (MAP), plasma norepinephrine (NE), epinephrine (E), and prolactin (PRL) to intravenous (iv) administration of bromocriptine, a dopamine agonist, and hexamethonium bromide, a ganglion blocker, were examined in conscious, unrestrained 4-wk DOCA/NaCl hypertensive rats." | 3.67 | Enhanced depressor effect of bromocriptine in the DOCA/NaCl hypertensive rat. ( Chen, YF; Nagahama, S; Oparil, S, 1985) |
"A central pressor effect of angiotensin II (ANG II) has been implicated in the pathogenesis of several forms of experimental hypertension." | 3.67 | Neurohumoral contributions to chronic angiotensin-induced hypertension. ( Bruner, CA; Fink, GD, 1986) |
"Twenty-one patients have been treated for hypertension with oral doses of hexamethonium salts, Apresoline(R) or combinations of both." | 3.63 | Hexamethonium and hydralazine hydrochloride for treatment of hypertension. ( STUPPY, LJ, 1954) |
"When hexamethonium was used to assess autonomic control of MAP, no differences in the decrease of MAP in response to ganglionic blockade were detected during the induction." | 1.40 | CNS neuroplasticity and salt-sensitive hypertension induced by prior treatment with subpressor doses of ANG II or aldosterone. ( Beltz, T; Clayton, SC; Johnson, AK; Xue, B; Zhang, Z, 2014) |
"Obesity is one of the major risk factors for cardiovascular disease and is often associated with increased oxidative stress and sympathoexcitation." | 1.35 | Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in obesity-induced hypertension. ( Ando, K; Fujita, M; Fujita, T; Kawarazaki, H; Matsui, H; Nagae, A, 2009) |
"Losartan-treated (LOS group, n = 10) and untreated rats served as controls (n = 11)." | 1.35 | Hyperinsulinemic rats are normotensive but sensitized to angiotensin II. ( Alexanderson, C; Andersson, IJ; Bergström, G; Holmäng, A; Johansson, ME; Skøtt, O, 2008) |
"Hypertension was induced in male Sprague-Dawley rats (n=40) by suprarenal aortic coarctation." | 1.30 | Food restriction attenuates the blood pressure response to paraventricular hypothalamic nuclei lesions in aortic coarctation hypertension. ( Casto, RM; DeMaria, JE; Overton, JM; VanNess, JM, 1998) |
"Nicotine (200 mg/kg) was administered as a single bolus, as infusions lasting 7." | 1.30 | Tachyphylaxis and sensitization to nicotine-induced tachycardiac and pressor effects after nicotine infusions. ( Cruz, SL; Vidrio, H, 1997) |
" At 16 weeks of age more-complete dose-response curves to the alpha 1-agonist methoxamine were also constructed." | 1.29 | Arterial hypertrophy and pressor responsiveness during development of hypertension in spontaneously hypertensive rats. ( Lee, RM; Leenen, FH; Tsoporis, J; Yuan, B, 1994) |
"Pretreatment with hexamethonium prevented neither acute nor more enduring behavioral deficits observed after TBI." | 1.28 | Blockade of acute hypertensive response does not prevent changes in behavior or in CSF acetylcholine (ACH) content following traumatic brain injury (TBI). ( Enters, EK; Kapasi, MZ; McDowell, KP; Pascua, JR; Povlishock, JT; Robinson, SE, 1992) |
"Pretreatment with prazosin (0." | 1.28 | Quipazine-induced hypertension in anaesthetized cats is mediated by central and peripheral 5-HT2 receptors: role of the ventrolateral pressor area. ( Bouysset, F; Laubie, M; Schmitt, H; Vayssettes-Courchay, C; Verbeuren, TJ, 1991) |
"Hexamethonium is a potent anti-hypertensive agent." | 1.23 | Use of hexamethonium in arterial hypertension. ( RYTAND, DA, 1954) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 196 (71.27) | 18.7374 |
1990's | 33 (12.00) | 18.2507 |
2000's | 32 (11.64) | 29.6817 |
2010's | 12 (4.36) | 24.3611 |
2020's | 2 (0.73) | 2.80 |
Authors | Studies |
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Braga, DCA | 1 |
Gomes, PM | 2 |
Batista, MAC | 1 |
de Souza, JA | 1 |
Bastos, JCSA | 1 |
Rodrigues-das-Dôres, RG | 1 |
Alzamora, AC | 2 |
de Souza, GHB | 1 |
de Moura, SAL | 1 |
Talvani, A | 1 |
Antunes, VR | 2 |
Cardoso, LM | 2 |
Ferreira, MJ | 1 |
Santos Ferreira Silva, MPD | 1 |
da Silva Dias, D | 1 |
Bernardes, N | 1 |
Irigoyen, MC | 1 |
De Angelis, K | 2 |
Toscano, CM | 1 |
Simões, MR | 1 |
Alonso, MJ | 1 |
Salaices, M | 1 |
Vassallo, DV | 2 |
Fioresi, M | 1 |
Sá, RWM | 1 |
Aguiar, GL | 1 |
Paes, MHS | 1 |
Lima, WG | 1 |
de Oliveira, LB | 1 |
Stocker, SD | 1 |
Guild, SJ | 1 |
Saxena, UA | 1 |
McBryde, FD | 1 |
Malpas, SC | 1 |
Ramchandra, R | 1 |
Nyquist, P | 1 |
Wang, Y | 1 |
Chen, L | 1 |
Wier, WG | 1 |
Zhang, J | 1 |
Clayton, SC | 1 |
Zhang, Z | 1 |
Beltz, T | 1 |
Xue, B | 5 |
Johnson, AK | 5 |
Koga, Y | 1 |
Hirooka, Y | 2 |
Araki, S | 1 |
Nozoe, M | 1 |
Kishi, T | 1 |
Sunagawa, K | 1 |
Nagae, A | 1 |
Fujita, M | 1 |
Kawarazaki, H | 1 |
Matsui, H | 1 |
Ando, K | 3 |
Fujita, T | 3 |
Badaue-Passos, D | 1 |
Guo, F | 3 |
Gomez-Sanchez, CE | 2 |
Hay, M | 4 |
Moreira, TS | 1 |
Takakura, AC | 1 |
Colombari, E | 2 |
Menani, JV | 2 |
Moritz, KM | 1 |
Dodic, M | 1 |
Jefferies, AJ | 1 |
Wintour, EM | 1 |
DeMatteo, R | 1 |
Singh, RR | 1 |
Evans, RG | 1 |
Singh, M | 1 |
Beltz, TG | 2 |
Yu, Y | 1 |
Zhao, G | 1 |
Walsh, E | 1 |
Shryock, JC | 1 |
Messina, E | 1 |
Wu, Y | 1 |
Zeng, D | 1 |
Xu, X | 1 |
Ochoa, M | 1 |
Baker, SP | 1 |
Hintze, TH | 1 |
Belardinelli, L | 1 |
Kuroki, MT | 1 |
Guzman, PA | 1 |
Fink, GD | 6 |
Osborn, JW | 3 |
Nishida, Y | 1 |
Tandai-Hiruma, M | 1 |
Kemuriyama, T | 1 |
Hagisawa, K | 1 |
Leal, AK | 2 |
Murphy, MN | 1 |
Iwamoto, GA | 1 |
Mitchell, JH | 2 |
Smith, SA | 2 |
Lu, WH | 1 |
Hsieh, KS | 1 |
Lu, PJ | 1 |
Wu, YS | 1 |
Ho, WY | 1 |
Lai, CC | 1 |
Wang, JS | 1 |
Ger, LP | 1 |
Hsiao, M | 1 |
Tseng, CJ | 1 |
Sato, MA | 1 |
Schoorlemmer, GH | 1 |
Lopes, OU | 1 |
CAMERON, AJ | 1 |
BURN, RA | 1 |
MILLS, LC | 4 |
MOYER, JH | 13 |
SMIRK, FH | 7 |
LANE, R | 1 |
MCQUEEN, EG | 1 |
PALMER, AJ | 1 |
KVALE, WF | 1 |
MCCALLA, LH | 1 |
CREECH, O | 1 |
FORD, RV | 7 |
KELLEY, RT | 1 |
FREIS, ED | 5 |
HIGGINS, TF | 1 |
SHAW, GB | 2 |
PAGE, IH | 2 |
PAGE, I | 1 |
TAYLOR, RD | 1 |
CORCORAN, AC | 1 |
LIAN, C | 1 |
SNYDER, BH | 1 |
JOHNSON, I | 2 |
MILLER, SI | 5 |
CARRAL, R | 1 |
TRANCHESI, J | 1 |
SOTO ROJAS, G | 1 |
HERRMANN, GR | 1 |
CONWAY, J | 2 |
RICH, CB | 1 |
HOLUBITSKY, WH | 1 |
ROEHM, DC | 1 |
KORY, RC | 1 |
MENEELY, GR | 1 |
MORRISON, B | 3 |
SHAPERA, RP | 1 |
LANG, FR | 1 |
ROMNEY, RB | 1 |
BULLINGTON, RH | 1 |
ABILDSKOV, JA | 1 |
RAY, CT | 1 |
BURCH, GE | 1 |
KLAYMAN, MI | 1 |
SILBERG, NR | 1 |
KARLEN, WS | 1 |
KUHN, PH | 1 |
HIRSHLEIFER, I | 1 |
SCHWARTZ, G | 1 |
FISHMAN, SI | 1 |
FANKHAUSER, AM | 1 |
HAUGEN, HN | 1 |
BLEGEN, EM | 1 |
SHAPIRO, AP | 1 |
GROLLMAN, A | 1 |
GROB, D | 2 |
LANGFORD, HG | 2 |
HILKER, RR | 1 |
RHOADS, PS | 1 |
BILLINGS, CE | 1 |
LIVESAY, WR | 1 |
SNYDER, HB | 1 |
Rønnov-Jessen, V | 5 |
Bech, V | 1 |
SCARBOROUGH, WR | 1 |
KATTUS, AA | 1 |
BRUNNER, D | 3 |
RAFSKY, HA | 1 |
HORONICK, A | 1 |
RAFSKY, JC | 1 |
RONNOV-JESSEN, V | 1 |
DEWAR, HA | 2 |
OWEN, SG | 1 |
JENKINS, AR | 1 |
CUBBERLY, RB | 1 |
WIESEL, LL | 1 |
LAMB, AE | 1 |
MURPHY, EA | 2 |
EASTWOOD, J | 1 |
STEEVES, LC | 1 |
SHEARS, AH | 1 |
SPELLER, SL | 1 |
McCUBBIN, JW | 1 |
SIEBER, HA | 3 |
GRIMSON, KS | 1 |
ORGAIN, ES | 3 |
SPURR, CL | 2 |
DUPUY, HJ | 1 |
SIGNORELLI, JJ | 1 |
HULL, E | 1 |
GALEN, WP | 2 |
JOHNSON, LL | 1 |
WILSON, AG | 1 |
HARINGTON, M | 1 |
ROSENHEIM, ML | 1 |
FRANCO, A | 1 |
CRUMPTON, CW | 2 |
ROWE, GG | 2 |
O'BRIEN, G | 1 |
MURPHY, QR | 2 |
DONIACH, I | 1 |
STEINER, RE | 2 |
STUPPY, LJ | 1 |
PERRETTA, A | 2 |
GUIDO, JJ | 1 |
WILSON, VH | 1 |
KEELEY, KJ | 1 |
HOOD, B | 1 |
BJORK, S | 1 |
ANGERVALL, G | 1 |
RUDBACK, H | 1 |
RYTAND, DA | 1 |
GREEN, DM | 1 |
ELLIS, EJ | 1 |
EURMAN, GH | 1 |
MENDLOWITZ, M | 1 |
CAPRETTI, G | 1 |
MAGNANI, B | 2 |
FALZOI, M | 1 |
GELATI, M | 1 |
GUNELLA, G | 1 |
SCHIMMLER, W | 1 |
SCHWALB, H | 1 |
CESARMAN, T | 1 |
TORRES DEL TORO, JM | 1 |
BARNETT, AJ | 1 |
FRASER, JR | 1 |
HAMILTON, M | 1 |
HENLEY, KS | 1 |
MANDELBAUM, H | 1 |
BROOK, J | 1 |
MANDELBAUM, RA | 1 |
ROSSI, B | 1 |
FERRARA, FA | 1 |
LEMAIRE, A | 1 |
LOEPER, J | 1 |
HOUSSET, E | 1 |
FRANCO, R | 1 |
ESCALADA, JG | 1 |
ALONSO JIMENO, S | 1 |
GONZALEZ MARTINEZ, A | 1 |
CRAWLEY, CJ | 2 |
SILVIS, GM | 2 |
STUMPE, WM | 2 |
WHITE, L | 1 |
THOMSEN, P | 1 |
ORTUZAR, R | 1 |
GONI, F | 1 |
ROJAS VILLEGAS, F | 1 |
SILVA LAFRENTZ, C | 1 |
TOLEDO, P | 1 |
SILVA CLARK, A | 1 |
VERA, G | 1 |
CHIAVERINI, R | 1 |
DA SILVA, WN | 1 |
DUKE, JE | 1 |
KLEH, J | 1 |
FAZEKAS, JF | 1 |
GUIDO, JG | 1 |
NAVARRET, E | 1 |
DENNIS, E | 3 |
McCONN, RG | 1 |
HUGHES, WM | 2 |
BEAZLEY, HL | 1 |
BIRKHEAD, NC | 1 |
ALLEN, EV | 1 |
RAST, CL | 2 |
SMITH, KS | 1 |
FOWLER, PB | 1 |
EDMUNDS, V | 1 |
HRENOFF, AK | 1 |
LOVISATO, L | 1 |
ROQUE, JA | 1 |
GENEST, J | 3 |
ROBILLARD, R | 3 |
TREMBLAY, G | 3 |
ADAMKIEWICZ, L | 3 |
CAPPS, RC | 1 |
WHITMORE, JJ | 1 |
BURCH, RR | 1 |
DE SIMONE, G | 1 |
MASELLIS, F | 1 |
GOLDSMITH, HJ | 1 |
BEAVEN, DW | 1 |
LAMBERT, HP | 1 |
TARJAN, P | 1 |
CSIPAK, Z | 1 |
BARATH, J | 1 |
BRUCE, GM | 1 |
MULLER, JC | 1 |
PRYOR, WW | 1 |
PIPBERGER, H | 1 |
KALIN, R | 1 |
ROSSIER, PH | 1 |
MCCLOSKEY, BJ | 1 |
FORD, R | 1 |
HERSCHBERGER, R | 1 |
SPENCE, W | 1 |
HERSHBERGER, RL | 1 |
BONA, E | 1 |
LOVEI, E | 1 |
PERALTA, A | 1 |
CASTANEDA, L | 1 |
ARREDONDO, J | 1 |
PEREZ, V | 1 |
CAMACHO, J | 1 |
ESTELA, M | 1 |
AUINGER, W | 1 |
HEROLD, G | 1 |
SALAND, G | 1 |
FISCHER, I | 1 |
HERNRIED, HP | 1 |
STOLIAR, ED | 1 |
ZURROW, HB | 1 |
ULLMANN, TD | 1 |
MENCZEL, J | 1 |
BARTORELLI, C | 1 |
GOLDBERG, B | 2 |
DALLE COSTE, P | 1 |
KLINGER, R | 1 |
ETTMAN, IK | 1 |
BOUCHILLON, CD | 1 |
HALFORD, HH | 1 |
BALCHUM, OJ | 1 |
GENSINI, G | 1 |
BLOUNT, SG | 1 |
LINDAUER, MA | 1 |
HAFKENSCHIEL, JH | 1 |
RESTREPO, G | 1 |
BAUER, H | 1 |
ERLSBACHER, O | 1 |
GEISBERGER, H | 1 |
MEDA, A | 1 |
DUGHERA, L | 1 |
PETERSEN, AG | 1 |
DODGE, M | 1 |
HELWIG, FC | 1 |
HAYNES, FW | 1 |
DEXTER, L | 1 |
VARELA DE SEIJAS AGUILAR, J | 1 |
FERNANDEZ ARENAS, M | 1 |
ESQUIVEL JIMENEZ, A | 1 |
MARCHAN COLADO, A | 1 |
DIAZ, JM | 1 |
KALUGINA, GV | 1 |
MOSCHINI-ANTINORI, E | 1 |
MENOTTI, A | 1 |
SPLENDIANI, G | 1 |
BARDIN, EV | 1 |
AKHREM-AKHREMOVICH, RM | 1 |
CHISTIAKOVA, MA | 1 |
KONONIACHENKO, VA | 1 |
CHAPIDZE, GE | 1 |
HAZARD, R | 1 |
RENIER CORNEC, A | 1 |
IVANOV, IuM | 1 |
BANTOVA, TG | 1 |
SANCETTA, SM | 1 |
RIOPELLE, JL | 1 |
MARKOVITZ, M | 1 |
KOIK, JV | 1 |
HICK, FK | 1 |
GRISSOM, RL | 1 |
GRIGOLATO, V | 1 |
ALLAN, J | 1 |
STEIN, DH | 1 |
HECHT, HH | 1 |
FERRARI, S | 1 |
MOSER, M | 1 |
ALTMAN, S | 1 |
SCHINDEL, L | 1 |
HIMBERT, J | 1 |
GRAS, H | 1 |
PHELAN, EL | 1 |
ERYETISHIR, I | 1 |
Toscano, CF | 1 |
Lahlou, S | 1 |
CAMPBELL, A | 1 |
ROBERTSON, E | 1 |
McNALLY, PA | 1 |
CUSACK, PB | 1 |
CUSACK, AL | 1 |
ALSTAD, KS | 1 |
MACKEY, WA | 1 |
COUNIHAN, T | 1 |
WERKO, L | 1 |
WADE, G | 1 |
FRISK, AR | 1 |
ELLASCH, H | 1 |
BECHGAARD, P | 1 |
IVERSEN, T | 1 |
NIELSEN, AL | 1 |
LOCKET, S | 1 |
SWANN, PG | 1 |
GRIEVE, WS | 1 |
PLAYER, HP | 1 |
FINNERTY, FA | 1 |
SCHNAPER, NW | 1 |
JOHNSON, RL | 2 |
PERSSON, I | 1 |
SCHROEDER, HA | 1 |
CHAPMAN, OW | 1 |
SCHNAPER, HW | 1 |
FREEMAN, Z | 1 |
KOK, JF | 1 |
DI CIO, AV | 1 |
KLEIN, L | 1 |
LOPEZ, A | 1 |
PAZZANESE, D | 1 |
DE BARROS, LM | 1 |
DE CAMARGO, FS | 1 |
BURT, CC | 1 |
GRAHAM, AJ | 1 |
RESTALL, PA | 1 |
Hendel, MD | 1 |
Collister, JP | 2 |
Pamidimukkala, J | 1 |
Seto, S | 2 |
Nagao, S | 2 |
Ozeki, S | 1 |
Tetsuo, H | 1 |
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Heimann, JC | 1 |
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Maeda, C | 1 |
Schaan, B | 1 |
Oliveira, E | 1 |
Oliveira, V | 1 |
Irigoyen, M | 1 |
Chen, X | 1 |
Patel, K | 1 |
Connors, SG | 1 |
Mendonca, M | 1 |
Welch, WJ | 2 |
Wilcox, CS | 2 |
Guzman, P | 1 |
Johansson, ME | 1 |
Andersson, IJ | 1 |
Alexanderson, C | 1 |
Skøtt, O | 1 |
Holmäng, A | 1 |
Bergström, G | 1 |
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Maixner, W | 1 |
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Ferrario, CM | 1 |
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Zukowska-Grojec, Z | 1 |
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Kitamura, Y | 1 |
Okamura, T | 1 |
Nakagawa, M | 3 |
Takeda, K | 3 |
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Itoh, H | 2 |
Nakata, T | 3 |
Sasaki, S | 3 |
Leenen, FH | 5 |
Yuan, B | 2 |
Tsoporis, J | 1 |
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Sato, Y | 2 |
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Kubo, T | 1 |
Yang, TL | 1 |
Yen, CT | 2 |
Chai, CY | 2 |
Wyss, JM | 3 |
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McCaughran, JA | 1 |
2 reviews available for hexamethonium and Hypertension
Article | Year |
---|---|
Long-term blood pressure control: is there a set-point in the brain?
Topics: Animals; Arginine Vasopressin; Baroreflex; Blood Pressure; Brain; Heart Rate; Hexamethonium; Homeost | 2012 |
The evolution of antihypertensive therapy.
Topics: Antihypertensive Agents; Bis-Trimethylammonium Compounds; Blood Pressure; Calcium Channel Blockers; | 1985 |
273 other studies available for hexamethonium and Hypertension
Article | Year |
---|---|
Effects of Psidium guajava L. leaves extract on blood pressure control and IL-10 production in salt-dependent hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Chromatography, Liquid; Hexamethonium; Hypertensio | 2022 |
Concurrent exercise training induces additional benefits to hydrochlorothiazide: Evidence for an improvement of autonomic control and oxidative stress in a model of hypertension and postmenopause.
Topics: Animals; Baroreflex; Blood Pressure; Female; Heart Rate; Hexamethonium; Hydrochlorothiazide; Hyperte | 2023 |
Sub-chronic lead exposure produces β
Topics: Animals; Arterial Pressure; Cardiovascular Diseases; Down-Regulation; Heart Rate; Hexamethonium; Hyp | 2017 |
Chronic high-sodium diet intake after weaning lead to neurogenic hypertension in adult Wistar rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure Determination; Heart Rate; Hexamethonium; Hypertens | 2017 |
Intracranial pressure influences the level of sympathetic tone.
Topics: Animals; Baroreflex; Blood Pressure; Brain; Cerebrovascular Circulation; Hexamethonium; Hypertension | 2018 |
Wet lungs and a battered brain stem: can we stop one if we cannot stop the other?
Topics: Animals; Encephalitis, Viral; Enterovirus Infections; Hexamethonium; Hypertension; Male; Pulmonary E | 2013 |
Intravital Förster resonance energy transfer imaging reveals elevated [Ca2+]i and enhanced sympathetic tone in femoral arteries of angiotensin II-infused hypertensive biosensor mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biosensing Techniques; Calcium; Calcium Signaling; | 2013 |
CNS neuroplasticity and salt-sensitive hypertension induced by prior treatment with subpressor doses of ANG II or aldosterone.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Brain; Brain-Derived | 2014 |
High salt intake enhances blood pressure increase during development of hypertension via oxidative stress in rostral ventrolateral medulla of spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cyclic N-Oxides; Heart Rate; Hexamethonium; Hypertension; Male; Medulla Obl | 2008 |
Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in obesity-induced hypertension.
Topics: Acetophenones; Animals; Blood Pressure; Brain; Cyclic N-Oxides; Heart Rate; Hexamethonium; Hypertens | 2009 |
Sex differences and central protective effect of 17beta-estradiol in the development of aldosterone/NaCl-induced hypertension.
Topics: Administration, Oral; Aldosterone; Animals; Blood Pressure; Body Weight; Brain; Disease Models, Anim | 2009 |
Antihypertensive effects of central ablations in spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Baroreflex; Blood Pressur | 2009 |
Haemodynamic characteristics of hypertension induced by prenatal cortisol exposure in sheep.
Topics: Animals; Antihypertensive Agents; Female; Hemodynamics; Hexamethonium; Hydrocortisone; Hypertension; | 2009 |
Protective actions of estrogen on angiotensin II-induced hypertension: role of central nitric oxide.
Topics: Angiotensin II; Animals; Blood Pressure; Blotting, Western; Disease Models, Animal; Enzyme Inhibitor | 2009 |
Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Drug Interactions; Electrop | 2011 |
Antiadrenergic and hemodynamic effects of ranolazine in conscious dogs.
Topics: Acetanilides; Adrenergic Antagonists; Animals; Autonomic Agents; Coronary Circulation; Dogs; Dose-Re | 2011 |
Time-dependent changes in autonomic control of splanchnic vascular resistance and heart rate in ANG II-salt hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Ganglionic Blockers; Heart Rate; Hexamethonium; Hypertensio | 2012 |
A role for nitric oxide within the nucleus tractus solitarii in the development of muscle mechanoreflex dysfunction in hypertension.
Topics: Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Ganglionic Blockers; Heart Rate; | 2012 |
Hexamethonium reverses the lethal cardiopulmonary damages in a rat model of brainstem lesions mimicking fatal enterovirus 71 encephalitis.
Topics: Animals; Biopsy, Needle; Brain Stem; Catecholamines; Diagnosis, Differential; Disease Models, Animal | 2013 |
Recovery of high blood pressure after chronic lesions of the commissural NTS in SHR.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antidiuretic Hormone Receptor Antagonists; Argini | 2003 |
Hexamethonium and glaucoma.
Topics: Glaucoma; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1952 |
Treatment of hypertension with orally and parenterally administered purified extracts of veratrum viride; comparison with ganglionic (Hexamethonium) and adrenergic blocking agents.
Topics: Adrenergic Antagonists; Ganglia; Hexamethonium; Hypertension; Veratrum; Veratrum Alkaloids | 1952 |
Hypotensive actions of hexamethonium bromide and some of its homologues; their use in high blood-pressure.
Topics: Autonomic Agents; Hexamethonium; Hypertension | 1952 |
The uses of hexamethonium.
Topics: Anesthesia; Cardiovascular Agents; Gastrointestinal Diseases; Hexamethonium; Humans; Hypertension; M | 1952 |
Treatment of hypertension with hexamethonium bromide.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1952 |
The management of hypertension with hexamethonium bromide.
Topics: Cardiovascular Agents; Disease Management; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1952 |
Hexamethonium and apresoline (1-hydrazinophthalazine).
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1952 |
Hexamethonium ileus.
Topics: Hexamethonium; Hypertension; Ileus; Intestinal Obstruction; Muscle Relaxants, Central | 1953 |
The effects of hexamethonium on certain manifestations of congestive heart failure.
Topics: Cardiovascular Agents; Heart Failure; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
Continous oral hexamethonium in essential hypertension; further experiences in treatment.
Topics: Cardiovascular Agents; Essential Hypertension; Hexamethonium; Hypertension; Muscle Relaxants, Centra | 1952 |
The treatment of severe arterial hypertension with hexamethonium and hydrazinophthalazine.
Topics: Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatholytics | 1953 |
[The treatment of severe arterial hypertension with hexamethonium and hydrazinophthalazine].
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1952 |
[Current medical and surgical therapy of permanent arterial hypertension; salt-free diet; tetraethylammonium; hexamethonium; extensive sympathectomies; arteriovenous fistula].
Topics: Arteriovenous Fistula; Diet, Sodium-Restricted; Fistula; Hexamethonium; Humans; Hypertension; Sympat | 1952 |
Results with oral hexamethonium alone and in combination with 1-hydrazinophthalazine (apresoline) in the therapy of hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1953 |
[Treatment of arterial hypertension with hexamethonium].
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1952 |
Some reactions to apresoline, hexamethonium and hydergine.
Topics: Cardiovascular Agents; Ergoloid Mesylates; Ergot Alkaloids; Hexamethonium; Hydralazine; Hypertension | 1952 |
Sensitivity of autonomic ganglia to hexamethonium in hypertension.
Topics: Autonomic Agents; Ganglia, Autonomic; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
The treatment of hypertension with oral hexamethonium.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
Responses of the ballistocardiogram in hypertensive patients to the acute administration of apresoline, hexamethonium, veratrone, regitine and sodium amytal.
Topics: Amobarbital; Ballistocardiography; Barbiturates; Cardiovascular Agents; Hexamethonium; Hydralazine; | 1953 |
Dibenzyline: results of therapy in patients with hypertension and a comparison with hexamethonium, 1-hydrazinophthalazine and semipurified extracts of veratrum.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Phenoxyb | 1953 |
Parenteral hexamethonium in hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
Essential hypertension; treatment with hexamethonium and apresoline.
Topics: Cardiovascular Agents; Essential Hypertension; Hexamethonium; Hydralazine; Hypertension; Muscle Rela | 1953 |
Orally administered hexamethonium chloride in hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
A preliminary report on clinical experiences with hexamethonium and 1-hydrazinophthalazine in the treatment of diastolic hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Humans; Hydralazine; Hypertension; Muscle Relaxants, Central; | 1953 |
Death associated with hexamethonium and 1-hydrazinophthalazine (apresoline) therapy.
Topics: Cardiovascular Agents; Death; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; S | 1953 |
The use of oral hexamethonium chloride (methium) in the treatment of hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
Clinical experiences with hexamethonium chloride in hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
The renal response to hexamethonium.
Topics: Hexamethonium; Hypertension; Kidney; Muscle Relaxants, Central | 1953 |
The acute effects of hexamethonium on renal hemodynamics in normotensive and hypertensive human subjects.
Topics: Blood Pressure; Hemodynamics; Hexamethonium; Humans; Hypertension; Kidney; Muscle Relaxants, Central | 1953 |
A critical evaluation of the hypotensive asction of hydrallazine, hexamethonium, tetraethylammonium and dibenzyline salts in human and experimental hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Hypotension; Muscle Relaxants, Cent | 1953 |
Further observations on the effects of autonomic blocking agents in patients with hypertension. I. General systemic effects of hexamethonium, pentamethonium, and hydrazinophthalazine.
Topics: Bis-Trimethylammonium Compounds; Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Mu | 1953 |
Clinical use of hydralazine and hexamethonium in treatment of hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1953 |
Treatment of hypertension with hexamethonium alone and in combination with apresoline.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1953 |
[Drug therapy of arterial hypertension; preliminary report on own experience with hexamethonium].
Topics: Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
Further observations on the effects of autonomic blocking agents in patients with hypertension. II. Hemodynamic, ballistocardiographic and electrocardiographic effects of hexamethonium and pentamethonium.
Topics: Bis-Trimethylammonium Compounds; Heart; Hemodynamics; Hexamethonium; Humans; Hypertension; Kidney; M | 1953 |
[The treatment of hypertension with hexamethonium and veriloid].
Topics: Hexamethonium; Hypertension; Muscle Relaxants, Central; Veratrum Alkaloids | 1953 |
The treatment of hypertension; experience of treatment with hexamethonium and veratrum viride preparation in 50 patients.
Topics: Hexamethonium; Hypertension; Muscle Relaxants, Central; Veratrum; Veratrum Alkaloids | 1953 |
Treatment of hypertension in elderly patients with methium chloride; preliminary report.
Topics: Aged; Cardiovascular Agents; Disease; Hexamethonium; Humans; Hypertension; Muscle Relaxants, Central | 1953 |
[Preliminary results in drug therapy of hypertension, with special reference to hexamethonium bromide].
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
Effect of hexamethonium bromide on the cerebral circulation in hypertension.
Topics: Brain; Cerebrovascular Circulation; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
The treatment of hypertension with hexamethonium and hydrazinophthalazine (apresoline).
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1953 |
Exercise tests during treatment of hypertension with hexamethonium.
Topics: Cardiovascular Agents; Exercise Test; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
Hexamethonium in polyvinylpyrrolidone.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central; Povidone | 1953 |
Newer drugs in hypertension; combined effects of 1-hydrazinophthalazine (apresoline) and hexamethonium salts; a preliminary report.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Salts; S | 1953 |
Preliminary observations of Rauwiloid-hexamethonium combined therapy of hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Humans; Hypertension; Muscle Relaxants, Central; Rauwolfia; Se | 1953 |
Modification of the hypotensive action of 1-hydrazinophthalazine (apresoline) by priscoline, hexamethonium and section of the carotid sinus and aortic buffer nerves in normal and renal hypertensive dogs.
Topics: Animals; Aorta; Carotid Sinus; Dogs; Hexamethonium; Hydralazine; Hypertension; Kidney; Muscle Relaxa | 1953 |
Newer drugs in the treatment of hypertension. I. Use of hexamethonium salts.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central; Salts | 1953 |
Hexamethonium in the chronic treatment of hypertension; its effect on renal hemodynamics and on the excretion of water and electrolytes.
Topics: Electrolytes; Hemodynamics; Hexamethonium; Hypertension; Kidney; Muscle Relaxants, Central; Water | 1953 |
Hexamethonium and apresoline; their effects on ambulatory hypertensive patients.
Topics: Cardiovascular Agents; Hexamethonium; Humans; Hydralazine; Hypertension; Muscle Relaxants, Central; | 1953 |
Outpatient treatment of hypertension with hexamethonium and apresoline.
Topics: Ambulatory Care; Cardiovascular Agents; Hexamethonium; Humans; Hydralazine; Hypertension; Muscle Rel | 1953 |
Effect of hexamethonium on normotensive heart failure; a possible correlation between the mechanism of essential hypertension and normotensive heart failure.
Topics: Essential Hypertension; Heart Failure; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
Hexamethonium in the treatment of hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1954 |
[Results of treatment of arterial hypertension with hexamethonium and apresoline].
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1953 |
[Hexamethonium in the treatment of hypertension].
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
The effect of hexamethonium bromide upon coronary flow, cardiac work and cardiac efficiency in normotensive and renal hypertensive dogs.
Topics: Animals; Blood Pressure; Dogs; Heart; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1954 |
Practical details of the treatment of hypertension by hexamethonium salts and by pentamethylene 1:5-bis-N-(N-methylpyrrolidinium) bitartrate (M. & B. 2050A).
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central; Salts | 1953 |
[Vegolysen retard, a new hexamethonium preparation with prolonged effect].
Topics: Aged; Hexamethonium; Humans; Hypertension; Muscle Relaxants, Central; Povidone | 1953 |
Lung changes during hexamethonium therapy for hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Lung; Muscle Relaxants, Central | 1954 |
Hexamethonium and hydralazine hydrochloride for treatment of hypertension.
Topics: Cardiovascular Agents; Constipation; Hexamethonium; Hydralazine; Hypertension; Hypotension, Orthosta | 1954 |
[Behavior of hexamethonium in arterial hypertension of distinct etiopathogenesis: hexamethonium test and personal technic].
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
The haemodynamic effects of hexamethonium bromide in patients with pulmonary hypertension and heart failure.
Topics: Blood Circulation; Heart Failure; Hemodynamics; Hexamethonium; Hypertension; Hypertension, Pulmonary | 1953 |
Muscular exercise in essential hypertension; the effect of hexamethonium chloride (C6).
Topics: Essential Hypertension; Exercise; Hexamethonium; Humans; Hypertension; Muscle Relaxants, Central; Mu | 1953 |
The treatment of the ambulatory hypertensive patient with hexamethonium administered orally.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1954 |
Use of hexamethonium in arterial hypertension.
Topics: Antihypertensive Agents; Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Centr | 1954 |
Intravenous hexamethonium sensitivity and responses to oral treatment.
Topics: Administration, Oral; Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1954 |
The effect of prolonged sodium depletion and of hydralazine hydrochloride and hexamethonium bromide on the digital vascular resistance in primary hypertension.
Topics: Essential Hypertension; Fingers; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central | 1954 |
[Use of hexamethonium salts in hypertensive disease].
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central; Salts | 1954 |
[Essential hypertension. II. Acute changes of renal function caused by hexamethonium bitartrate].
Topics: Essential Hypertension; Hexamethonium; Hypertension; Kidney; Muscle Relaxants, Central | 1954 |
[Relations between arterial circulation and renal function following administration of hexamethonium bromide].
Topics: Arteries; Blood Circulation; Hexamethonium; Hypertension; Kidney; Muscle Relaxants, Central; Pharmac | 1954 |
[Essay of the treatment of essential arterial hypertension with oral hexamethonium chloride].
Topics: Essential Hypertension; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
The mechanism of arterial hypertension: a comparison of the effects of hexamethonium bromide in hypertensive and normotensive persons.
Topics: Blood Pressure; Cardiovascular Agents; Hexamethonium; Humans; Hypertension; Muscle Relaxants, Centra | 1954 |
Changes in peripheral circulation and body temperature after hexamethonium bromide.
Topics: Blood Circulation; Body Temperature; Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Rela | 1954 |
Bleeding peptic ulcer complicating hydralazine and hexamethonium bromide therapy.
Topics: Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Peptic Ulcer; Peptic Ulcer Hemo | 1954 |
[Action of oral hexamethonium chloride in the treatment of arterial hypertension].
Topics: Cardiovascular Agents; Hexamethonium; Humans; Hypertension; Muscle Relaxants, Central | 1954 |
[Hexamethonium in the treatment of arterial hypertension].
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1954 |
[Effect of hexamethonium on photoplethysmographic tracings in hypertension].
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1953 |
[Hexamethonium in therapy of acute hypertensive crises, as illustrated by case reports].
Topics: Hexamethonium; Hypertension; Muscle Relaxants, Central | 1954 |
[Practice and results of the use of hexamethonium in the treatment of arterial hypertension].
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1954 |
Appraisal of methium chloride with Rauwolfia in ambulatory hypertensive patients.
Topics: Hexamethonium; Hypertension; Hypnotics and Sedatives; Muscle Relaxants, Central; Rauwolfia | 1954 |
[Hexamethonium, apresoline and pyretotherapy in the treatment of arterial hypertension].
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Hyperthermia, Induced; Muscle Relax | 1954 |
[Observations on the treatment of arterial hypertension with hexamethonium with hydergine].
Topics: Cardiovascular Agents; Ergoloid Mesylates; Ergot Alkaloids; Hexamethonium; Hypertension; Muscle Rela | 1954 |
[Hexamethonium in therapy of arterial hypertension].
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1954 |
Outpatient treatment of hypertension with hexamethonium and hydralazine; a preliminary report.
Topics: Ambulatory Care; Hexamethonium; Humans; Hydralazine; Hypertension; Muscle Relaxants, Central; Outpat | 1954 |
Hexamethonium treatment of arterial hypertension.
Topics: Hexamethonium; Humans; Hypertension; Osteomyelitis | 1954 |
Cerebral hemodynamic studies on hypertensive-atherosclerotic subjects during hexamethonium therapy.
Topics: Arteriosclerosis; Brain; Cardiovascular System; Hemodynamics; Hexamethonium; Hypertension; Muscle Re | 1954 |
[Hexamethonium bromide test in hypertensive endocrine diseases].
Topics: Cardiovascular Agents; Endocrine System Diseases; Hexamethonium; Hypertension; Muscle Relaxants, Cen | 1954 |
Treatment of hypertension; long-term results with alseroxylon (rauwiloid) alone and combined with hexamethonium administered orally.
Topics: Cardiovascular Agents; Hexamethonium; Humans; Hypertension; Hypnotics and Sedatives; Muscle Relaxant | 1954 |
Comparison of effects on hypertension of hexamethonium and pentapyrrolidinium injected subcutaneously.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1954 |
A comparison of the effects of hexamethonium alone and in combination with 1-hydrazinophthalazine (apresoline) in the treatment of hypertension.
Topics: Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatholytics | 1953 |
Blood pressure reduction in arterial hypertension by hexamethonium and pentapyrrolidinium salts.
Topics: Blood Pressure; Cardiovascular Agents; Hexamethonium; Hypertension; Hypotension; Muscle Relaxants, C | 1954 |
Hypertension and its control by hexamethonium.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1954 |
Hexamethonium contributing to fatal shock in hypertensive epistaxis.
Topics: Cardiovascular Agents; Epistaxis; Hexamethonium; Hypertension; Muscle Relaxants, Central; Shock | 1954 |
[Clinical study of hexamethonium in arterial hypertension].
Topics: Cardiovascular Agents; Hexamethonium; Humans; Hypertension; Muscle Relaxants, Central | 1954 |
Hexamethonium and apresoline (L-hydrazinophthalazine) in the treatment of malignant hypertension; report of a case.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Hypertension, Malignant; Muscle Rel | 1954 |
[Administration of hexamethonium to patients with severe hypertension].
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1954 |
Treatment of hypertension with oral reserpine alone and in combination with hydralazine or hexamethonium.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Hypnotics and Sedatives; Muscle Rel | 1955 |
The effect of hexamethonium upon cerebral blood flow and metabolism in patients with premalignant and malignant hypertension.
Topics: Brain; Cerebrovascular Circulation; Hexamethonium; Humans; Hypertension; Hypertension, Malignant; Mu | 1955 |
The effects of intravenous hexamethonium on venous pressure of normotensive and hypertensive patients with and without congestive heart failure.
Topics: Blood Pressure; Blood Pressure Determination; Heart Failure; Hexamethonium; Humans; Hypertension; Ve | 1955 |
[Effect of hexamethonium loading test on ballistocardiogram and ECG in hypertensive subjects].
Topics: Ballistocardiography; Cardiovascular Agents; Electrocardiography; Hexamethonium; Humans; Hypertensio | 1954 |
Severe hypertension treated with hexamethonium bromide in retard medium.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1955 |
[New trends in the treatment of hypertension. II. Experimental investigations on two new Hungarian preparations; hexamethonium, N. 310].
Topics: Autonomic Agents; Autonomic Nervous System; Hexamethonium; Humans; Hypertension; Muscle Relaxants, C | 1955 |
Permanent bilateral blindness following the use of hexamethonium chloride.
Topics: Blindness; Hexamethonium; Hypertension; Muscle Relaxants, Central; Vision Disorders | 1955 |
Newer drugs in the treatment of hypertension. II. Use of hexamethonium in combination with hydralazine.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1955 |
[Vectorcardiographic studies in hypertensive patients with massive blood pressure reduction by hexamethonium; contribution to the theory of ventricular gradients].
Topics: Blood Pressure; Hexamethonium; Humans; Hypertension; Hypotension; Muscle Relaxants, Central; Vectorc | 1955 |
Hematuria during treatment of severe hypertension with hexamethonium bromide and pentolinium tartrate.
Topics: Cardiovascular Agents; Hematuria; Hexamethonium; Hypertension; Muscle Relaxants, Central; Pentoliniu | 1955 |
Pentolinium and hexamethonium combined with Rauwolfia in the treatment of hypertension.
Topics: Antihypertensive Agents; Cardiovascular Agents; Hexamethonium; Hypertension; Hypnotics and Sedatives | 1955 |
Methium chloride with reserpine, a new antihypertensive combination.
Topics: Antihypertensive Agents; Cardiovascular Agents; Chlorides; Hexamethonium; Hypertension; Muscle Relax | 1955 |
The effect of pentolinium on renal hemodynamics and water and electrolyte excretion: a comparison with hexamethonium.
Topics: Electrolytes; Hemodynamics; Hexamethonium; Hypertension; Kidney; Muscle Relaxants, Central; Pentolin | 1956 |
[The treatment of hypertension with hexamethonium bromide and Rauwolfia preparations].
Topics: Antihypertensive Agents; Hexamethonium; Hypertension; Hypnotics and Sedatives; Muscle Relaxants, Cen | 1955 |
[The hexamethonium in hypertensive encephalopathy].
Topics: Hexamethonium; Hypertension; Hypertensive Encephalopathy; Muscle Relaxants, Central; Vascular Diseas | 1955 |
[Studies of the effect of small doses of hexamethonium on blood circulation in normal and hypertensive subjects].
Topics: Blood Circulation; Cardiovascular Agents; Hexamethonium; Humans; Hypertension; Muscle Relaxants, Cen | 1956 |
Clinical observations on the oral use of hexamethonium, hydralazine, and rauwolfia extracts in essential hypertension.
Topics: Antihypertensive Agents; Essential Hypertension; Hexamethonium; Humans; Hydralazine; Hypertension; M | 1956 |
The effect of a ganglionic blocking agent (hexamethonium) on renal function and on excretion of water and electrolytes in hypertension and in congestive heart failure.
Topics: Electrolytes; Ganglionic Blockers; Heart Failure; Hexamethonium; Humans; Hypertension; Kidney Functi | 1956 |
[Prolonged treatment of essential hypertension with hexamethonium and serpasil].
Topics: Antihypertensive Agents; Essential Hypertension; Hexamethonium; Hypertension; Muscle Relaxants, Cent | 1956 |
Renal haemodynamic effects of hypotensive drugs. I. Acute effects of hexamethonium bromide before and after treatment with reserpine.
Topics: Antihypertensive Agents; Hemodynamics; Hexamethonium; Hexamethonium Compounds; Humans; Hypertension; | 1957 |
Renal haemodynamic effects of hypotensive drugs. I. Acute effects of hexamethonium bromide before and after treatment with reserpine.
Topics: Antihypertensive Agents; Hemodynamics; Hexamethonium; Hexamethonium Compounds; Humans; Hypertension; | 1957 |
Renal haemodynamic effects of hypotensive drugs. I. Acute effects of hexamethonium bromide before and after treatment with reserpine.
Topics: Antihypertensive Agents; Hemodynamics; Hexamethonium; Hexamethonium Compounds; Humans; Hypertension; | 1957 |
Renal haemodynamic effects of hypotensive drugs. I. Acute effects of hexamethonium bromide before and after treatment with reserpine.
Topics: Antihypertensive Agents; Hemodynamics; Hexamethonium; Hexamethonium Compounds; Humans; Hypertension; | 1957 |
[Rauwolfia serpentina extracts combined with hexamethonium in therapy of arterial hypertension in diabetics].
Topics: Diabetes Complications; Diabetes Mellitus; Hexamethonium; Hexamethonium Compounds; Humans; Hypertens | 1957 |
Gastrointestinal roentgen findings due to untoward effects of hexamethonium.
Topics: Hexamethonium; Hexamethonium Compounds; Humans; Hypertension; Intestinal Obstruction; Stomach; Stoma | 1957 |
The effect of hexamethonium upon the pulmonary vascular resistance in mitral stenosis.
Topics: Hexamethonium; Hexamethonium Compounds; Humans; Hypertension; Mitral Valve Stenosis; Vascular Diseas | 1957 |
Hexamethonium chloride with reserpine in the treatment of severe essential hypertension.
Topics: Essential Hypertension; Hexamethonium; Hexamethonium Compounds; Humans; Hypertension; Reserpine | 1958 |
Vascular reactivity in experimental hypertension measured after hexamethonium.
Topics: Blood Vessels; Hexamethonium; Hypertension; Nitrites; Norepinephrine | 1958 |
Pneumonitis as a complication of hexamethonium therapy.
Topics: Glomerulonephritis; Hexamethonium; Hexamethonium Compounds; Humans; Hypertension; Pneumonia; Vascula | 1958 |
[Experiences with hexamethonium salts in rectal administration in hypertension].
Topics: Administration, Rectal; Hexamethonium; Hexamethonium Compounds; Hypertension; Salts | 1958 |
[Date on the action of hexamethonium in arterial hypertension].
Topics: Hexamethonium; Hexamethonium Compounds; Hypertension; Phoeniceae | 1958 |
Pulmonary changes associated with hexamethonium therapy.
Topics: Hexamethonium; Hexamethonium Compounds; Hypertension; Pneumonia | 1959 |
Pressor effect of subcutaneous renin in dogs, and effect of reserpine, 1-hydrazinophthalazine and hexamethonium on renin hypertension.
Topics: Animals; Dogs; Endopeptidases; Hexamethonium; Hexamethonium Compounds; Hydralazine; Hydrolases; Hype | 1959 |
[Result of treatment of arterial hypertension with hexamethonium, thalazine & other drugs].
Topics: Hexamethonium; Hexamethonium Compounds; Humans; Hydralazine; Hypertension; Hypertension, Portal | 1959 |
[Dynamics of serum protein fractions during the treatment of hypertension with Rauwolfia serpentina preparations and hexonium].
Topics: Bis-Trimethylammonium Compounds; Blood Proteins; Hexamethonium; Hypertension; Rauwolfia; Serum Album | 1961 |
Hexamethonium trial as a diagnostic test of the principal forms of arterial hypertension
Topics: Diagnostic Tests, Routine; Hexamethonium; Hexamethonium Compounds; Hypertension | 1960 |
[Treatment of patients with hypertension with hexonium and reserpine].
Topics: Hexamethonium; Hexamethonium Compounds; Humans; Hypertension; Reserpine | 1962 |
[The treatment of hypertension by Depressin].
Topics: Antihypertensive Agents; Hexamethonium; Humans; Hypertension; Imidazoles; Pentobarbital; Reserpine | 1962 |
[Effect of Gangleron and Hexonium on regional blood circulation in patients with hypertension].
Topics: Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Humans; Hypertension; Plethysmography | 1962 |
[DIFFERENTIATION BY HEXAMETHONIUM OF THE HYPERTENSIVE ACTIONS RESPECTIVELY EXERCISED BY POTASSIUM ION AND ACETYLCHOLINE].
Topics: Acetylcholine; Animals; Blood Pressure; Blood Pressure Determination; Dogs; Exercise; Hexamethonium; | 1964 |
[ON DEPRESSIN THERAPY OF PATIENTS WITH RESERPINE-RESISTANT FORMS OF HYPERTENSION].
Topics: Antihypertensive Agents; Hexamethonium; Humans; Hypertension; Reserpine | 1964 |
[USE OF HEXONIUM IN A POLYCLINIC].
Topics: Drug Therapy; Hexamethonium; Hexamethonium Compounds; Humans; Hypertension; Reserpine | 1965 |
Acute hemodynamic effects of hexamethonium (C6) in patients with emphysematous pulmonary hypertension.
Topics: Emphysema; Hemodynamics; Hexamethonium; Humans; Hypertension; Hypertension, Pulmonary; Muscle Relaxa | 1955 |
Pulmonary complications during treatment with hexamethonium.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Lung; Muscle Relaxants, Central | 1955 |
Hexamethonium, hydralazine and rauwolfia serpentina therapy in hypertension.
Topics: Antihypertensive Agents; Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Rel | 1955 |
[Combination of hexamethonium and hydrazinophthalazine in the treatment of arterial hypertension].
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1954 |
[Treatment of essential arterial hypertension with hexamethonium chloride].
Topics: Essential Hypertension; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1955 |
Oral hexamethonium in hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1955 |
Cardiovascular and renal responses to the combination of hexamethonium and 1-hydrazinophthalazine (apresoline) in hypertensive subjects.
Topics: Cardiovascular System; Hexamethonium; Hydralazine; Hypertension; Kidney; Muscle Relaxants, Central; | 1955 |
[Prolonged-action hexamethonium in therapy of arterial hypertension].
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1955 |
Evaluation of drug therapy of hypertension; experience with ansolysen, hexamethonium, apresoline, and reserpine.
Topics: Drug Therapy; Hexamethonium; Hydralazine; Hypertension; Pentolinium Tartrate; Reserpine | 1955 |
Hypertension treatment with alkaloids of Veratrum viride and Veratrum album alone or in combination with hexamethonium salts.
Topics: Alkaloids; Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central; Salts; Ver | 1955 |
[Effect of hexamethonium on renal circulation and function in cardiacs and hypertensives].
Topics: Heart Diseases; Hexamethonium; Hexamethonium Compounds; Humans; Hypertension; Kidney; Renal Circulat | 1959 |
Observations on the responses of rats with spontaneous hypertension and control rats to pressor drugs and to hexamethonium.
Topics: Arginine Vasopressin; Disease; Epinephrine; Hexamethonium; Hypertension; Rats; Rodent Diseases; Thio | 1962 |
Blood pressure effects of intravenous apomorphine in conscious deoxycorticosterone-acetate salt-hypertensive rats.
Topics: Animals; Apomorphine; Behavior, Animal; Blood Pressure; Desoxycorticosterone; Domperidone; Dopamine | 2003 |
Treatment of severe hypertension with hexamethonium bromide.
Topics: Bis-Trimethylammonium Compounds; Blood Pressure; Blood Pressure Determination; Hexamethonium; Hypert | 1950 |
Some results of treatment with hexamethonium bromide in cases of vascular hypertension.
Topics: Bis-Trimethylammonium Compounds; Blood Pressure; Blood Pressure Determination; Hexamethonium; Hypert | 1951 |
Hexamethonium bromide in vascular hypertension.
Topics: Bis-Trimethylammonium Compounds; Blood Pressure; Blood Pressure Determination; Hexamethonium; Hypert | 1951 |
Treatment of arterial hypertension by penta- and hexamethonium salts; based on 150 tests on hypertensives of varied aetiology and 53 patients treated for periods of two to fourteen months.
Topics: Bis-Trimethylammonium Compounds; Blood Pressure; Blood Pressure Determination; Hexamethonium; Hypert | 1951 |
Veratrum viride and hexamethonium in the treatment of severe diastolic hypertension.
Topics: Autonomic Nervous System Diseases; Bis-Trimethylammonium Compounds; Blood Pressure; Blood Pressure D | 1951 |
Oral hexamethonium bromide in essential hypertension.
Topics: Bis-Trimethylammonium Compounds; Blood Pressure; Blood Pressure Determination; Essential Hypertensio | 1951 |
Syncope during hexamethonium administration.
Topics: Animals; Anura; Bis-Trimethylammonium Compounds; Blood Pressure; Blood Pressure Determination; Hexam | 1951 |
Effect of hexamethonium bromide in arterial hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1951 |
Treatment of hypertension with hexamethonium bromide.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1951 |
[Hexamethonium therapy of essential hypertension].
Topics: Essential Hypertension; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1951 |
M. & B. 1863, a homologue of hexamethonium, in treatment of hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1952 |
The treatment of hypertension with hexamethonium.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1952 |
[Hexamethonium bromide in hypertension therapy].
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1951 |
Control of hypertension by hexamethonium and 1-hydrazinophthalazine; preliminary observations.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central | 1952 |
Comparison of the effects of veratrum alkaloids and of hexamethonium bromide upon the blood pressure in arterial hypertension.
Topics: Blood Pressure; Blood Pressure Determination; Cardiovascular Agents; Hexamethonium; Humans; Hyperten | 1952 |
Clinical evaluation of 1-hydrazinophthalazine (C-5968) in hypertension, with special reference to alternating treatment with hexamethonium.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central | 1952 |
Some observations on the use of hexamethonium bromide in the treatment of ambulant hypertensives.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1952 |
Treatment of hypertension; results with hexamethonium salts administered orally.
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central; Salts | 1952 |
[Hexamethonium salts in hypertension].
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central; Salts | 1952 |
[Action on hexamethonium bromide on arterial hypertension].
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1952 |
NEW approved drugs: hexamethonium bromide; hydralazine hydrochloride.
Topics: Drug Approval; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central | 1952 |
[Hexamethonium therapy of arterial hypertension].
Topics: Cardiovascular Agents; Hexamethonium; Hypertension; Muscle Relaxants, Central | 1952 |
[Penta- and hexamethonium in arterial hypertension].
Topics: Hexamethonium; Hypertension; Muscle Relaxants, Central; Oligosaccharides; Rubiaceae | 1952 |
Pentamethonium and hexamethonium iodide in investigation of peripheral vascular disease and hypertension.
Topics: Bis-Trimethylammonium Compounds; Blood Pressure; Blood Pressure Determination; Blood Vessels; Hexame | 1950 |
The treatment of high blood pressure with hexamethonium iodide.
Topics: Blood Pressure; Blood Pressure Determination; Hexamethonium; Hypertension; Iodine; Iodine Isotopes | 1950 |
Contribution of the subfornical organ to angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Drinking; Heart Rate; Hexamethoniu | 2005 |
Sex differences in the development of angiotensin II-induced hypertension in conscious mice.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Consciousness; Female; Ganglionic Blockers; Hea | 2005 |
Contribution of central nitric oxide to the regulation of blood pressure and sodium balance in DOCA-salt hypertension.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Desoxycorticosterone; Drinking; Eating; Enzyme Inhibi | 2006 |
Central action of increased osmolality to support blood pressure in deoxycorticosterone acetate-salt rats.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Pressure; Brain; Car | 2006 |
Exercise pressor reflex function is altered in spontaneously hypertensive rats.
Topics: Animals; Arteries; Baroreflex; Blood Pressure; Echocardiography; Electric Stimulation; Ganglionic Bl | 2006 |
Increased sympathetic activity in rats submitted to chronic intermittent hypoxia.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Chronic Disease; Disease Models, A | 2007 |
Sympathetic and renin-angiotensin systems contribute to increased blood pressure in sucrose-fed rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Body Weight; Captop | 2007 |
Chronic salt loading and cardiovascular-associated changes in experimental diabetes in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arginine Vasopressin; Baroreflex; Blood Glucose; B | 2007 |
Acute antihypertensive action of Tempol in the spontaneously hypertensive rat.
Topics: Amitrole; Animals; Antihypertensive Agents; Blood Pressure; Buthionine Sulfoximine; Catalase; Cromak | 2007 |
Effect of peripheral sympathetic nerve dysfunction on salt sensitivity of arterial pressure.
Topics: Animals; Antihypertensive Agents; Autonomic Nervous System Diseases; Blood Pressure; Dose-Response R | 2008 |
Hyperinsulinemic rats are normotensive but sensitized to angiotensin II.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Ag | 2008 |
Post-resistance exercise hypotension in spontaneously hypertensive rats is mediated by nitric oxide.
Topics: Animals; Blood Pressure; Hexamethonium; Hypertension; Hypotension; Male; NG-Nitroarginine Methyl Est | 2008 |
Preload and afterload reduction in treating congestive heart failure.
Topics: Autonomic Nerve Block; Heart Failure; Hemodynamics; Hexamethonium; Hexamethonium Compounds; Humans; | 1984 |
Factors influencing the altered pain perception in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Heart Rate; Hexamethonium; Hexamethonium Compounds; Hypertension; Male; Mus | 1982 |
GABA receptor binding and hemodynamic responses to ICV GABA in adult spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain; gamma-Aminobutyric Acid; Heart Rate; Hemody | 1983 |
[Combined treatment of hypertension patients].
Topics: Adolescent; Adult; Antihypertensive Agents; Clonidine; Drug Combinations; Drug Evaluation; Drug Ther | 1984 |
Contribution of vasopressin to hypertension after solitary tract lesioning in the dog.
Topics: Acute Disease; Animals; Arginine Vasopressin; Blood Pressure; Dogs; Heart Rate; Hexamethonium; Hexam | 1984 |
Effect of methylguanidine on rat blood pressure: role of endothelial nitric oxide synthase.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothe | 1995 |
Contribution of alpha- and beta- adrenoceptors and neuropeptide-Y to autonomic dysreflexia.
Topics: Animals; Autonomic Nervous System Diseases; Blood Pressure; Ganglionic Blockers; Heart Rate; Hexamet | 1995 |
Neural mechanism of hypertension by nitric oxide synthase inhibitor in dogs.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Dogs; Female; Heart Rate; Hexamethoni | 1993 |
Antihypertensive effect of taurine on salt-induced hypertension.
Topics: Animals; Blood Pressure; Brain; Hexamethonium; Hypertension; Hypothalamus; Injections, Intraventricu | 1994 |
Arterial hypertrophy and pressor responsiveness during development of hypertension in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Ganglionic Blockers; Heart Ventricles; Hemodynamics; Hexamethonium; Hexamet | 1994 |
Involvement of the sympathetic nervous system in antihypertensive effect of cicletanine in salt-loaded young spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dopamine; Hexamethonium; Hypertension; Male; Norep | 1994 |
Excitatory amino acid receptors in the rostral ventrolateral medulla mediate hypertension induced by carotid body chemoreceptor stimulation.
Topics: Animals; Blood Pressure; Carotid Body; Cordotomy; Excitatory Amino Acid Antagonists; Heart Rate; Hex | 1994 |
Study of the hemodynamic contributing factors of spontaneously hypertensive rats in the early stage of established hypertension.
Topics: Animals; Blood Pressure; Cardiac Output; Cerebrovascular Disorders; Hemodynamics; Hexamethonium; Hex | 1993 |
Contribution of the sympathetic nervous system to salt-sensitivity in lifetime captopril-treated spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Hexamethonium; Hypertension; | 1995 |
Parasympathetic component of 5-hydroxytryptamine-induced pulmonary dysfunctions in healthy calves.
Topics: Aging; Animals; Apnea; Atropine; Bradycardia; Cattle; Cattle Diseases; Cholinergic Agents; Ganglioni | 1996 |
Central GABAergic mechanisms are defective in salt-induced hypertension in borderline hypertensive rats.
Topics: Animals; Antihypertensive Agents; Bicuculline; Blood Pressure; Consciousness; GABA Antagonists; gamm | 1995 |
Contribution of the sympathetic nervous system to hypertensive response to insulin excess in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Clonidine; Ganglion | 1996 |
Tachyphylaxis and sensitization to nicotine-induced tachycardiac and pressor effects after nicotine infusions.
Topics: Animals; Blood Pressure; Bradycardia; Decerebrate State; Drug Administration Schedule; Ganglionic Bl | 1997 |
Autonomic control of ultradian and circadian rhythms of blood pressure, heart rate, and baroreflex sensitivity in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Autonomic Nervous System; Blood Pressure; Circadian Rhythm; H | 1997 |
Reduction of insulin resistance attenuates the development of hypertension in sucrose-fed SHR.
Topics: Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Captopril; Catecholamines; Dietary | 1997 |
Sympathetic nervous system and hypertension during prolonged TxA2/PGH2 receptor activation in rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antihypertensive Agents | 1997 |
Food restriction attenuates the blood pressure response to paraventricular hypothalamic nuclei lesions in aortic coarctation hypertension.
Topics: Adrenergic alpha-Agonists; Animals; Aortic Coarctation; Atropine; Blood Glucose; Blood Pressure; Bod | 1998 |
Dietary-sodium-induced cardiac remodeling in spontaneously hypertensive rat versus Wistar-Kyoto rat.
Topics: Angiotensin II; Animals; Blood Pressure; Catecholamines; Ganglionic Blockers; Heart Rate; Heart Vent | 1998 |
Nitric oxide dependent vasodilation in young spontaneously hypertensive rats.
Topics: Aging; Animals; Antihypertensive Agents; Blood Pressure; Drug Interactions; Enzyme Inhibitors; Hexam | 1998 |
Attenuation of cardiac but not vascular component in baroreflex of spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Atropine; Baroreflex; Blood Pressure; B | 1998 |
The brain renin-angiotensin system contributes to the hypertension in mice containing both the human renin and human angiotensinogen transgenes.
Topics: Angiotensins; Animals; Antihypertensive Agents; Arginine Vasopressin; Blood Pressure; Brain Chemistr | 1998 |
Daily exercise enhances acetylcholine-induced dilation in mesenteric and hindlimb vasculature of hypertensive rats.
Topics: Acetylcholine; Animals; Cyclooxygenase Inhibitors; Endothelium, Vascular; Female; Follow-Up Studies; | 1999 |
Role of cholinergic receptors in adrenal catecholamine secretion in spontaneously hypertensive rats.
Topics: Adrenal Glands; Animals; Atropine; Electric Stimulation; Epinephrine; Hexamethonium; Hypertension; I | 1999 |
The pharmacological effects of an aqueous extract from Acacia nilotica seeds.
Topics: Acacia; Acetylcholine; Animals; Atropine; Blood Pressure; Cats; Dose-Response Relationship, Drug; Gu | 1999 |
Elevated sympathetic activity contributes to hypertension and salt sensitivity in diabetic obese Zucker rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Glucose; B | 2000 |
Mechanisms of increased venous smooth muscle tone in desoxycorticosterone acetate-salt hypertension.
Topics: Animals; Atrasentan; Blood Volume; Consciousness; Desoxycorticosterone; Endothelin Receptor Antagoni | 2000 |
Right ventricular pressure and dilation during pressure overload determine dysfunction after pressure overload.
Topics: Animals; Atropine; Cardiac Catheterization; Cardiotonic Agents; Cardiovascular Agents; Diastole; Dil | 2000 |
Pathophysiological role of leptin in obesity-related hypertension.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; alpha-MSH; Animals; Blood Pressure; Body | 2000 |
Angiotensin in the nucleus tractus solitarii contributes to neurogenic hypertension caused by chronic nitric oxide synthase inhibition.
Topics: Angiotensin Receptor Antagonists; Angiotensins; Animals; Antihypertensive Agents; Benzimidazoles; Bi | 2000 |
Inhibition of abnormal hindquarter vascular tone in spontaneously hypertensive rats with chlorpromazine.
Topics: Animals; Chlorpromazine; Drug Administration Schedule; Female; Ganglionic Blockers; Hexamethonium; H | 2000 |
Control of renin secretion from adrenal gland in transgenic Ren-2 and normal rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitor | 2001 |
Effect of an ET(B)-selective and a mixed ET(A/B) endothelin receptor antagonist on venomotor tone in deoxycorticosterone-salt hypertension.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Endothelin Receptor Antagonists; Endothelin-1; Hemody | 2001 |
Contribution of central amiloride-sensitive transport systems to the development of hypertension in spontaneously hypertensive rats.
Topics: Amiloride; Angiotensin II; Animals; Blood Pressure; Body Weight; Brain; Carrier Proteins; Diuretics; | 2001 |
Is clinical research still too haphazard.
Topics: Antihypertensive Agents; Biomedical Research; Clinical Trials as Topic; Hexamethonium; Humans; Hyper | 2001 |
Contribution of endogenous vasopressin to regional hemodynamics in borderline-hypertensive Hiroshima rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antidiuretic Hormone Receptor Antagonists; Argini | 2002 |
Alpha4beta2 nicotinic acetylcholine receptor activation ameliorates impairment of spontaneous alternation behavior in stroke-prone spontaneously hypertensive rats, an animal model of attention deficit hyperactivity disorder.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Attention Deficit Disorder with Hyperactivity; Beh | 2002 |
History of research into hypertension.
Topics: Bretylium Compounds; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; History, 20th Cent | 1992 |
Role of the sympathetic nervous system in the alcohol-guanabenz hemodynamic interaction.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Catecholamines; Dose-Response Relationship, Drug; | 1992 |
Blockade of acute hypertensive response does not prevent changes in behavior or in CSF acetylcholine (ACH) content following traumatic brain injury (TBI).
Topics: Acetylcholine; Analysis of Variance; Animals; Axonal Transport; Behavior, Animal; Blood Pressure; Br | 1992 |
Hexamethonium and midazolam terminate dysrhythmias and hypertension caused by intracerebroventricular bupivacaine in rabbits.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Brain; Bupivacaine; Halotha | 1991 |
Lateral parabrachial nucleus and angiotensin II-induced hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Blood Pressure; Gan | 1991 |
Quipazine-induced hypertension in anaesthetized cats is mediated by central and peripheral 5-HT2 receptors: role of the ventrolateral pressor area.
Topics: Animals; Blood Pressure; Cats; Cyproheptadine; Female; Heart Rate; Hexamethonium; Hexamethonium Comp | 1991 |
Autoregulatory capacity in renal and mesenteric vasculatures of mineralocorticoid hypertensive dogs.
Topics: Adenosine; Animals; Blood Pressure; Desoxycorticosterone; Dogs; Female; Ganglionic Blockers; Hexamet | 1991 |
Suppression of the renin-angiotensin system induced by streptozotocin treatment in neonatal spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Diabetes Mellitus, Experim | 1990 |
Further evidence for abnormal hindquarter tone in spontaneously hypertensive rats.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Ganglia, Sympathetic; Ganglionic Blockers; Hexamethon | 1990 |
Role of afferent renal nerves in spontaneous hypertension in rats.
Topics: Afferent Pathways; Animals; Female; Ganglia, Spinal; Ganglionectomy; Hexamethonium; Hexamethonium Co | 1989 |
Paraventricular nucleus lesions attenuate the development of hypertension in DOCA/salt-treated rats.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Desoxycorticosterone; Epinephrine; Hexamethonium; Hex | 1989 |
Contribution of the baroreflex afferent nerves to the production of vasoconstricted hypertension in volume-expanded dogs.
Topics: Afferent Pathways; Animals; Blood Pressure; Blood Volume; Diuresis; Dogs; Hemodynamics; Hexamethoniu | 1989 |
Role of autonomic nervous system on heart rate in experimental hypertension.
Topics: Animals; Atropine; Autonomic Nervous System; Heart Conduction System; Heart Rate; Hemicholinium 3; H | 1985 |
Chronic salt loading and central adrenergic mechanisms in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Central Nervous System; Clonidine; Dopamine; Heart Rate; Hexamethonium; Hex | 1985 |
Enhanced depressor effect of bromocriptine in the DOCA/NaCl hypertensive rat.
Topics: Adrenal Medulla; Animals; Blood Pressure; Bromocriptine; Depression, Chemical; Desoxycorticosterone; | 1985 |
Neurohumoral contributions to chronic angiotensin-induced hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Blood Pressure; Blo | 1986 |
[Effect of depression and dopegit on regional blood flow in patients with hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Blood Circulation; Female; Hexamethonium; Hexamethonium Compou | 1986 |
The adrenergic nervous control of fluid transport in the small intestine of normotensive and spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic Fibers; Animals; Blood Pressure; Electric Stimulation; Hexa | 1986 |
The role of the sympathetic nervous system in 2-kidney DOCA-hypertensive Yucatan miniature swine.
Topics: Animals; Blood Pressure; Cardiac Output; Catecholamines; Desoxycorticosterone; Female; Heart Rate; H | 1986 |
Brain renin angiotensin system contributes to the salt-induced enhancement of hypertension in SHR.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Captopril; Dose-Response Relationship, Drug; Hexamet | 1986 |
Role of sympathetic nervous system in hypotensive action of taurine in DOCA-salt rats.
Topics: Animals; Blood Pressure; Cold Temperature; Desoxycorticosterone; Hexamethonium; Hexamethonium Compou | 1987 |
[Changes in the sensitivity of cardiovascular beta adrenergic receptors after sinoaortic denervation in rats].
Topics: Animals; Blood Pressure; Denervation; Female; Hexamethonium; Hexamethonium Compounds; Hypertension; | 1986 |
Dietary sodium restriction, blood pressure and sympathetic activity in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Epinephrine; Ganglia, Sympathetic; He | 1987 |
The area postrema in deoxycorticosterone-salt hypertension in rats.
Topics: Animals; Blood Pressure; Body Water; Cerebral Ventricles; Desoxycorticosterone; Ganglionic Blockers; | 1987 |
Prevention of hypertension and maintenance of normotension in spontaneously hypertensive rats is dependent on continuous severe dietary sodium restriction.
Topics: Aging; Animals; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Eating; Hexamethonium; Hexamet | 1987 |
Dietary sodium intake and age in spontaneously hypertensive rats: effects on blood pressure and sympathetic activity.
Topics: Aging; Animals; Blood Pressure; Body Weight; Catecholamines; Diet, Sodium-Restricted; Growth Disorde | 1987 |
Balance among autonomic controls of heart rate in neonatal spontaneously hypertensive and borderline hypertensive rats.
Topics: Age Factors; Animals; Animals, Newborn; Antihypertensive Agents; Atenolol; Atropine Derivatives; Aut | 1988 |
Ontogeny of blood pressure in the inbred Dahl hypertension-sensitive and -resistant rat.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Hexamethonium; Hexamethonium Compounds; Hypertension; | 1988 |