pirinixic acid has been researched along with Hypertension in 6 studies
pirinixic acid: structure
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic rosiglitazone treatment retards hypertension development, but the associated prohypertrophy effect calls for a cautious use of this thiazolidinedindione in the treatment of insulin resistance syndrome associated with hypertension." | 5.32 | Beneficial and deleterious effects of rosiglitazone on hypertension development in spontaneously hypertensive rats. ( De Champlain, J; Wang, R; Wilson, TW; Wu, L, 2004) |
| "Hypertension is associated with endothelial dysfunction, which favors the release of endothelium-derived contracting factors, including vasoconstrictor prostanoids and reactive oxygen species." | 1.48 | PPAR-α agonists acutely inhibit Ca ( Chen, H; Leung, SWS; Man, RYK, 2018) |
| "Chronic rosiglitazone treatment retards hypertension development, but the associated prohypertrophy effect calls for a cautious use of this thiazolidinedindione in the treatment of insulin resistance syndrome associated with hypertension." | 1.32 | Beneficial and deleterious effects of rosiglitazone on hypertension development in spontaneously hypertensive rats. ( De Champlain, J; Wang, R; Wilson, TW; Wu, L, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Willson, TM | 1 |
| Brown, PJ | 1 |
| Sternbach, DD | 1 |
| Henke, BR | 1 |
| Chen, H | 1 |
| Man, RYK | 1 |
| Leung, SWS | 1 |
| Qu, C | 1 |
| Leung, SW | 1 |
| Vanhoutte, PM | 1 |
| Man, RY | 1 |
| Wu, L | 1 |
| Wang, R | 1 |
| De Champlain, J | 1 |
| Wilson, TW | 1 |
| Nakagawa, K | 1 |
| Holla, VR | 1 |
| Wei, Y | 1 |
| Wang, WH | 1 |
| Gatica, A | 1 |
| Wei, S | 1 |
| Mei, S | 1 |
| Miller, CM | 1 |
| Cha, DR | 1 |
| Price, E | 1 |
| Zent, R | 1 |
| Pozzi, A | 1 |
| Breyer, MD | 1 |
| Guan, Y | 1 |
| Falck, JR | 1 |
| Waterman, MR | 1 |
| Capdevila, JH | 1 |
| Zahradka, P | 1 |
2 reviews available for pirinixic acid and Hypertension
| Article | Year |
|---|---|
The PPARs: from orphan receptors to drug discovery.
Topics: Animals; Diabetes Mellitus; Drug Design; Humans; Hyperlipidemias; Hypertension; Inflammation; Ligand | 2000 |
Cardiovascular actions of the peroxisome proliferator-activated receptor-alpha (PPARalpha) agonist Wy14,643.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Cardiovascular System; Disease Models, Animal; Hu | 2007 |
4 other studies available for pirinixic acid and Hypertension
| Article | Year |
|---|---|
PPAR-α agonists acutely inhibit Ca
Topics: Animals; Antihypertensive Agents; Antioxidants; Aorta; Disease Models, Animal; Fenofibrate; Hydrogen | 2018 |
Wy14643 improves vascular function in the aorta of the spontaneously hypertensive rat mainly by activating peroxisome proliferator-activated receptors alpha.
Topics: Animals; Aorta, Thoracic; Fenofibrate; Hypertension; In Vitro Techniques; Male; Peroxisome Prolifera | 2012 |
Beneficial and deleterious effects of rosiglitazone on hypertension development in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Hypertension; Hypertrophy, Left Ventricular; Kidney; Male; Myocard | 2004 |
Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel.
Topics: Amiloride; Animals; Arachidonic Acids; Blood Pressure; Cytochrome P-450 Enzyme System; Cytochrome P4 | 2006 |