mianserin has been researched along with Hypertension in 16 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study investigates the effects of acute and chronic mianserin administration in patients with essential hypertension established on long term treatment with either clonidine or methyldopa." | 5.05 | Absence of an effect of mianserin on the actions of clonidine or methyldopa in hypertensive patients. ( Elliott, HL; McLean, K; Reid, JL; Sumner, DJ, 1983) |
| "Mirtazapine appears to be relatively benign in overdose, associated with tachycardia, mild hypertension and mild CNS depression not requiring intervention." | 3.80 | Mirtazapine overdose is unlikely to cause major toxicity. ( Berling, I; Isbister, GK, 2014) |
| "1 The interaction between mianserin and centrally-acting antihypertensive drugs was evaluated in normal volunteers and in patients with essential hypertension receiving either clonidine or methyldopa." | 3.66 | Assessment of the interaction between mianserin and centrally-acting antihypertensive drugs. ( Elliott, HL; Reid, JL; Whiting, B, 1983) |
| "3." | 2.64 | Effect of mianserin hydrochloride on peripheral uptake mechanisms for noradrenaline and 5-hydroxytryptamine in man. ( Coppen, A; Ghose, K; Swade, C; Wood, K, 1978) |
| "Mirtazapine is a noradrenergic and specific serotonergic antidepressant." | 1.35 | Influence of mirtazapine on the hypotensive activity of enalapril and propranolol in spontaneously hypertensive rats. ( Andrzejczak, D; Kocon, K; Zieba, R, 2008) |
| "Mirtazapine is a new antidepressant with a tetracyclic chemical structure that is not related to selective serotonin reuptake inhibitors, tricyclic antidepressants, or monoamine oxidase inhibitors." | 1.31 | Hypertensive urgency induced by an interaction of mirtazapine and clonidine. ( Abo-Zena, RA; Bobek, MB; Dweik, RA, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (37.50) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berling, I | 1 |
| Isbister, GK | 1 |
| Andrzejczak, D | 1 |
| Kocon, K | 1 |
| Zieba, R | 1 |
| Famularo, G | 1 |
| Gasbarrone, L | 1 |
| De Virgilio, A | 1 |
| Minisola, G | 1 |
| Silva, AL | 1 |
| Cabral, AM | 1 |
| Abreu, GR | 1 |
| Pires, JG | 1 |
| Bissoli, NS | 1 |
| Ramage, AG | 1 |
| Mutschler, J | 1 |
| Czell, D | 1 |
| Kaps, M | 1 |
| Manzl, G | 1 |
| Elliott, HL | 2 |
| McLean, K | 1 |
| Sumner, DJ | 1 |
| Reid, JL | 2 |
| Anthony, M | 1 |
| Whiting, B | 1 |
| Bottlender, R | 1 |
| Erfurth, A | 1 |
| Hoff, P | 1 |
| Möller, HJ | 1 |
| Zedkova, L | 1 |
| Coupland, NJ | 1 |
| Jensen, JB | 1 |
| Abo-Zena, RA | 1 |
| Bobek, MB | 1 |
| Dweik, RA | 1 |
| Spierings, EL | 1 |
| Robson, RD | 1 |
| Antonaccio, MJ | 1 |
| Saelens, JK | 1 |
| Liebman, J | 1 |
| Coppen, A | 1 |
| Ghose, K | 1 |
| Swade, C | 1 |
| Wood, K | 1 |
| Burgess, CD | 1 |
| Turner, P | 1 |
| Wadsworth, J | 1 |
1 review available for mianserin and Hypertension
| Article | Year |
|---|---|
Serotonin antagonists.
Topics: Cyproheptadine; Depression; Ergotamine; Humans; Hypertension; Ketanserin; Lisuride; Methysergide; Mi | 1984 |
3 trials available for mianserin and Hypertension
| Article | Year |
|---|---|
Absence of an effect of mianserin on the actions of clonidine or methyldopa in hypertensive patients.
Topics: Aged; Blood Pressure; Clonidine; Dibenzazepines; Drug Interactions; Female; Heart Rate; Humans; Hype | 1983 |
Effect of mianserin hydrochloride on peripheral uptake mechanisms for noradrenaline and 5-hydroxytryptamine in man.
Topics: Antidepressive Agents; Bethanidine; Blood Platelets; Clinical Trials as Topic; Depression; Dibenzaze | 1978 |
Cardiovascular responses to mianserin hydrochloride: a comparison with tricyclic antidepressant drugs.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bethanidine; Blood Pressure; Cardiovascular | 1978 |
12 other studies available for mianserin and Hypertension
| Article | Year |
|---|---|
Mirtazapine overdose is unlikely to cause major toxicity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Critical Care; Databases, Factual | 2014 |
Influence of mirtazapine on the hypotensive activity of enalapril and propranolol in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Do | 2008 |
Mirtazapine-associated hyponatremia in an elderly patient.
Topics: Aged; Antidepressive Agents, Tricyclic; Depression; Female; Humans; Hypertension; Hyponatremia; Mian | 2009 |
Chronic treatment with mianserin prevents DOCA-salt hypertension in rats--evidence for the involvement of central 5-HT2 receptors.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Dose-Response Relationship, Drug; Drinking; Heart Rat | 2005 |
[Psychotic symptoms in a case of locked-in syndrome].
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Brain Stem; Cerebral Hemorrhage; Delusions; | 2006 |
Assessment of the interaction between mianserin and centrally-acting antihypertensive drugs.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clonidine; Dibenzazepines; Double-Blind Method | 1983 |
[Mianserin-induced hypertension 2 weeks after discontinuation of tranylcypromine].
Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Cardiomyopathy, Dilated; Depressive | 1997 |
Hypertension during coprescription of mirtazapine and low-dose amitriptyline.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Therapy, Combination; Hum | 1998 |
[Edema tendency, dyspnea and hypertension in the treatment with mirtazapine (Remeron)].
Topics: Adrenergic alpha-Antagonists; Adult; Antidepressive Agents, Tricyclic; Dyspnea; Edema; Female; Hista | 1999 |
Hypertensive urgency induced by an interaction of mirtazapine and clonidine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Antidepressive Agents; Antihypertens | 2000 |
Acute and chronic hypertensive headache and hypertensive encephalopathy.
Topics: Acute Disease; Antidepressive Agents; Antihypertensive Agents; Anxiety; Arterioles; Cerebral Arterie | 2002 |
Antagonism by mianserin and classical alpha-adrenoceptor blocking drugs of some cardiovascular and behavioral effects of clonidine.
Topics: Adrenergic alpha-Antagonists; Animals; Avoidance Learning; Behavior, Animal; Clonidine; Dibenzazepin | 1978 |