Compounds > tropodifene
Page last updated: 2024-09-23

tropodifene

Description

tropodifene: russian drug; RN given refers to (endo)-isomer; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID65621
CHEMBL ID2105598
MeSH IDM0054443

Synonyms (21)

Synonym
tropodifene
[(1r,5s)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-(4-acetyloxyphenyl)-2-phenylpropanoate
CHEMBL2105598
7w0qt89ycd ,
tropine 3-(p-hydroxyphenyl-2-phenylpropionate (ester) acetate (ester)
unii-7w0qt89ycd
tropodifenum
15790-02-0
tropodifeno [inn-spanish]
tropodifeno
tropine 3-(p-hydroxyphenyl)-2-phenylpropionate (ester) acetate (ester)
tropodifenum [inn-latin]
endo-4-(acetyloxy)-alpha-phenylbenzenepropanoic acid, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester
3alpha-tropanyl 3-(4-acetoxyphenyl)-2-phenylpropionat
tropodifene [inn]
(+/-)-tropine 3-(p-hydroxyphenyl-2-phenylpropionate (ester) acetate (ester)
CS-7311
HY-U00313
Q27268922
DTXSID401043138
AKOS040740459

Research

Studies (17)

TimeframeStudies, This Drug (%)All Drugs %
pre-199013 (76.47)18.7374
1990's4 (23.53)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (4.17%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other23 (95.83%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
phentolamine[no description available]medium40imidazoles;
phenols;
substituted aniline;
tertiary amino compound		alpha-adrenergic antagonist;
vasodilator agent
tolazoline[no description available]medium10imidazolesalpha-adrenergic antagonist;
antihypertensive agent;
vasodilator agent
alprenolol[no description available]medium10secondary alcohol;
secondary amino compound		anti-arrhythmia drug;
antihypertensive agent;
beta-adrenergic antagonist;
sympatholytic agent
ouabain[no description available]medium1011alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone		anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite
hydralazine[no description available]medium10azaarene;
hydrazines;
ortho-fused heteroarene;
phthalazines		antihypertensive agent;
vasodilator agent
prazosin[no description available]medium20aromatic ether;
furans;
monocarboxylic acid amide;
piperazines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
aminophylline[no description available]medium10mixturebronchodilator agent;
cardiotonic drug
histamine[no description available]medium20aralkylamino compound;
imidazoles		human metabolite;
mouse metabolite;
neurotransmitter
propranolol[no description available]medium100naphthalenes;
propanolamine;
secondary amine		anti-arrhythmia drug;
antihypertensive agent;
anxiolytic drug;
beta-adrenergic antagonist;
environmental contaminant;
human blood serum metabolite;
vasodilator agent;
xenobiotic
atropine[no description available]medium30
amiodarone[no description available]medium101-benzofurans;
aromatic ketone;
organoiodine compound;
tertiary amino compound		cardiovascular drug
angiotensin ii[no description available]medium10amino acid zwitterion;
angiotensin II		human metabolite
bradykinin[no description available]medium10oligopeptidehuman blood serum metabolite;
vasodilator agent
diphenhydramine[no description available]medium10ether;
tertiary amino compound		anti-allergic agent;
antidyskinesia agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
antitussive;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
oneirogen;
sedative
lysergic acid diethylamide[no description available]medium10ergoline alkaloid;
monocarboxylic acid amide;
organic heterotetracyclic compound		dopamine agonist;
hallucinogen;
serotonergic agonist
tropacine[no description available]medium10
xenon[no description available]medium10monoatomic xenon;
noble gas atom;
p-block element atom
nialamide[no description available]medium10organonitrogen compound;
organooxygen compound
potassium chloride[no description available]medium10inorganic chloride;
inorganic potassium salt;
potassium salt		fertilizer
phenoxybenzamine[no description available]medium10aromatic amine
guanethidine[no description available]medium10azocanes;
guanidines		adrenergic antagonist;
antihypertensive agent;
sympatholytic agent
isoproterenol[no description available]medium10catechols;
secondary alcohol;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
sympathomimetic agent
tyramine[no description available]medium10monoamine molecular messenger;
primary amino compound;
tyramines		EC 3.1.1.8 (cholinesterase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter
fentanyl[no description available]medium10anilide;
monocarboxylic acid amide;
piperidines		adjuvant;
anaesthesia adjuvant;
anaesthetic;
intravenous anaesthetic;
mu-opioid receptor agonist;
opioid analgesic
thromboplastin[no description available]medium10
dihydroergotoxine[no description available]medium10
dinoprostone[no description available]medium10prostaglandins Ehuman metabolite;
mouse metabolite;
oxytocic
piperidines[no description available]medium10
ephedrine[no description available]medium10phenethylamine alkaloid;
phenylethanolamines		bacterial metabolite;
environmental contaminant;
nasal decongestant;
plant metabolite;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
phenylephrine[no description available]medium10phenols;
phenylethanolamines;
secondary amino compound		alpha-adrenergic agonist;
cardiotonic drug;
mydriatic agent;
nasal decongestant;
protective agent;
sympathomimetic agent;
vasoconstrictor agent
morphine[no description available]medium10morphinane alkaloid;
organic heteropentacyclic compound;
tertiary amino compound		anaesthetic;
drug allergen;
environmental contaminant;
geroprotector;
mu-opioid receptor agonist;
opioid analgesic;
plant metabolite;
vasodilator agent;
xenobiotic
ConditionIndicatedRelationship StrengthStudiesTrials
Arrhythmia0low10
Arrhythmias, Cardiac0low10
Arrythmia0low10
Blood Pressure, High0low10
Bradyarrhythmia0low10
Bradyarrhythmias0low10
Bradycardia0low10
Brain Vascular Disorders0low10
Cardiac Arrhythmia0low10
Cardiac Arrhythmias0low10
Cardiac Dysrhythmia0low10
Cardiac Output, Low0low10
Cardiovascular Stroke0low20
Cerebrovascular Diseases0low10
Cerebrovascular Disorders0low10
Cerebrovascular Insufficiency0low10
Cerebrovascular Occlusion0low10
Chronic Disease0low10
Chronic Illness0low10
Chronically Ill0low10
Complication, Postoperative0low10
Cor Pulmonale0low10
Disease, Pulmonary Heart0low10
Diseases, Pulmonary Heart0low10
Heart Attack0low20
Heart Disease, Pulmonary0low10
Heart Diseases, Pulmonary0low10
Hypertension0low10
Hypertension, Pulmonary0low10
Intracranial Vascular Disorders0low10
Ischemia0low10
Low Cardiac Output0low10
Low Cardiac Output Syndrome0low10
Myocardial Infarct0low20
Myocardial Infarction0low20
Postoperative Complications0low10
Pulmonary Heart Disease0low10
Pulmonary Heart Diseases0low10
Pulmonary Hypertension0low10
Vascular Diseases, Intracranial0low10