Page last updated: 2024-08-26

1,4-dihydropyridine and Hypertension

1,4-dihydropyridine has been researched along with Hypertension in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (9.52)	18.7374
1990's	16 (25.40)	18.2507
2000's	26 (41.27)	29.6817
2010's	14 (22.22)	24.3611
2020's	1 (1.59)	2.80

Authors

Authors	Studies
Jiang, X; Malone, DC; Manini, TM; Pepine, C; Solberg, LM; Vouri, SM; Winterstein, AG	1
Esterhuizen, TM; Mugendi, GA; Mutua, FM; Natale, P; Strippoli, GF	1
Agabiti Rosei, C; Agabiti Rosei, E; Bertacchini, F; Brami, V; Caletti, S; Coschignano, MA; De Ciuceis, C; Duse, S; Muiesan, ML; Paini, A; Petelca, A; Rizzoni, D; Rossini, C; Salvetti, M; Semeraro, F; Trapletti, V	1
Arima, H; Chaugai, S; Kerman, SRJ; Sepehry, AA; Sherpa, LY	1
Arima, H; Chalmers, J; Harrap, S; Hirakawa, Y; Mancia, G; Patel, A; Poulter, N; Williams, B; Woodward, M; Zoungas, S	1
Bakris, GL; Yamout, H	1
Eguchi, K	1
Choi, H; Kim, YS; Koh, SH; Lee, KY; Lee, YJ; Park, HH; Son, JW; Yoo, A	1
Ellerbeck, EF; Mahnken, JD; Phadnis, MA; Shireman, TI; Wetmore, JB	1
Fendrikova, AV; Pyhalova, NE; Sirotenko, DV; Skibitsky, VV	1
Horio, T; Kamide, K; Kawano, Y; Matayoshi, T; Miwa, Y; Miyata, T; Nakahama, H; Nakamura, S; Takiuchi, S; Yang, J; Yasuda, H; Yoshihara, F; Yoshii, M	1
Higaki, J; Horiuchi, M; Imaizumi, T; Ito, S; Katayama, S; Matsuoka, H; Ogihara, T; Rakugi, H; Saito, I; Saruta, T; Shimada, K; Shimamoto, K; Takishita, S	1
Glendenning, P; Grasko, JM; Nguyen, HH	1
Hu, D; Huang, J; Kario, K; Kim, CH; Lau, T; Li, Y; Park, CG; Wang, JG; Wei, YQ; Yan, P; Zhang, W	1
Krzemiński, TF; Mitręga, K; Żorniak, M	1
Anderson, G; Austin, PC; Bell, CM; Brotchie, J; Fox, S; Gruneir, A; Marras, C; Rochon, P; Wang, X	1
Alviar, CL; Bangalore, S; Benjo, AM; Devarapally, S; Doherty, B; Javed, F; Kang, H; Messerli, FH; Nadkarni, GN; Romero, J	1
Bucci, A; Cuccurullo, F; Lapenna, D; Mezzetti, A; Pierdomenico, SD	1
Allen, AS; Chua, BS; Griffith, TF; Klassen, PS; Reddan, DN; Szczech, LA	1
van Zwieten, PA	2
Birkenhäger, WH; Bulpitt, CJ; Celis, H; de Leeuw, PW; Fagard, R; Fletcher, AE; Forette, F; Leonetti, G; McCormack, P; Nachev, C; O'Brien, E; Rodicio, JL; Rosenfeld, J; Sarti, C; Staessen, JA; Thijisq, L; Tuomilehto, J; Webster, J; Yodfat, Y; Zanchetti, A	1
Elliott, HL; Meredith, PA	1
Ferro, A; Welsh, L	1
Handler, J	1
Logan, A	1
Bakris, GL; Greene, T; Hebert, L; Lea, J; Lipkowitz, M; Massry, S; Middleton, J; Miller, E; Rostand, SG; Smith, W	1
Mielcarek, J; Naskrent, M	1
Aizawa, Y; Atarashi, H; Fukatani, M; Hirai, M; Hirayama, A; Inoue, H; Kamakura, S; Kato, T; Kodama, I; Koretsune, Y; Kumagai, K; Kurachi, Y; Mitamura, H; Nakaya, H; Ogawa, S; Ohe, T; Ohtsu, H; Okumura, K; Saikawa, T; Sakurai, M; Sugi, K; Watanabe, E; Yamashita, T; Yamazaki, T	1
Birkenhäger, WH; de Leeuw, PW; Richart, T; Staessen, JA	1
Berenshteĭn, NV; Burmistrova, LF; Iskenderov, BG; Lokhina, TV	1
Haller, H	1
Altura, BM; Altura, BT	1
Inoue, T; Kimura, T; Kita, Z; Kobayashi, T; Nishino, S; Oizumi, K; Yoshiya, H	1
Fujihara, Y; Inoue, T; Kimura, T; Kobayashi, T; Nishino, S; Oizumi, K	1
Rao, MR; Xu, Y	1
Trenkwalder, P	1
Vetrovec, GW	1
Chrysant, S; Dunlay, MC; Fitzpatrick, V; Francischetti, EA; Goldberg, AI; Sweet, CS	1
Beevers, DG; Sleight, P	1
Chobanian, AV	1
Leenen, FH	1
Fischmeister, R; Hoerter, J; Hove-Madsen, L; Legssyer, AK	1
Messerli, FH	1
Agabiti-Rosei, E; Bettoni, G; Castellano, M; Muiesan, ML; Porteri, E; Rizzoni, D; Zulli, R	1
Arabidze, GG; Birkenhäger, WH; Bulpitt, CJ; Celis, H; de Leeuw, P; Dollery, CT; Duggan, J; Fagard, RH; Fletcher, AE; Gasowski, J; Kawecka-Jaszcz, K; Leonetti, G; Nachev, C; Rodico, JL; Rosenfeld, J; Safar, M; Seux, ML; Staessen, JA; Thijs, L; Tuomilehto, J; Webster, J; Yodfat, Y	1
Abe, K; Imai, Y; Saito, T; Saruta, T; Suzuki, H; Tsuji, I	1
Birkenhäger, WH; Fagard, RH; Staessen, JA	1
Doris, PA; Kähönen, M; Kalliovalkama, J; Pekki, A; Pörsti, I; Tolvanen, JP; Voipio, J; Wu, X; Ylitalo, P	1
Bell, A	1
Grad, R; Hanley, S	1
Amenta, F; Sabbatini, M; Tomassoni, D	1
Laragh, J	1
MacGregor, GA; Missouris, CG; Sirker, A	1
Masuyama, Y; Nishio, I; Tsuda, K; Tsuda, S	1
Celis, H; Fagard, RH; Gasowski, J; Staessen, JA; Thijs, L; Wang, JG	1
Devereux, RB; Palmieri, V	1
Rudin, M; Sauter, A	1
Lee, HR; Roeske, WR; Watson, M; Yamamura, HI	1
Federmann, A; Garthoff, B; Hirth, C; Kazda, S; Stasch, JP	1
Gerard, P; Huchet, AM; Huguet, F; Narcisse, G	1
Burnett, JC; Ritter, SG; Strong, CG; Zachariah, PK	1
Bäärnhielm, C; Westerlund, C	1

Reviews

17 review(s) available for 1,4-dihydropyridine and Hypertension

Article	Year
Calcium channel blockers for people with chronic kidney disease requiring dialysis. The Cochrane database of systematic reviews, 2020, Oct-01, Volume: 10 Topics: Adult; Antihypertensive Agents; Bias; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Humans; Hypertension; Hypotension; Randomized Controlled Trials as Topic; Renal Dialysis; Renal Insufficiency, Chronic	2020
Effects of Long- and Intermediate-Acting Dihydropyridine Calcium Channel Blockers in Hypertension: A Systematic Review and Meta-Analysis of 18 Prospective, Randomized, Actively Controlled Trials. Journal of cardiovascular pharmacology and therapeutics, 2018, Volume: 23, Issue:5 Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic; Treatment Outcome	2018
[24-hour perfect BP-lowering therapy using long-acting dihydropyridine calcium channel blockers]. Nihon rinsho. Japanese journal of clinical medicine, 2014, Volume: 72, Issue:8 Topics: Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Dihydropyridines; Humans; Hypertension	2014
Use of dihydropyridine calcium channel blockers in the management of hypertension in Eastern Asians: a scientific statement from the Asian Pacific Heart Association. Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:4 Topics: Asia, Eastern; Calcium Channel Blockers; Dihydropyridines; Humans; Hypertension; Randomized Controlled Trials as Topic; Societies, Medical; Treatment Outcome	2011
[Derivatives of 1,4-dihydropyridines as "priviledged structures" and their pharmacological potential]. Kardiologia polska, 2011, Volume: 69 Suppl 3 Topics: Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Humans; Hypertension; Structure-Activity Relationship	2011
Efficacy and safety of dual calcium channel blockade for the treatment of hypertension: a meta-analysis. American journal of hypertension, 2013, Volume: 26, Issue:2 Topics: Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic; Treatment Outcome	2013
Dihydropyridine calcium channel blockers: basic pharmacological similarities but fundamental therapeutic differences. Journal of hypertension, 2004, Volume: 22, Issue:9 Topics: Calcium Channel Blockers; Dihydropyridines; Humans; Hypertension	2004
Drug treatment of essential hypertension: the case for initial combination therapy. International journal of clinical practice, 2004, Volume: 58, Issue:10 Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Cardiovascular Diseases; Dihydropyridines; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Middle Aged; Renin-Angiotensin System; Sodium	2004
[Hypertension as a source of cognitive regression, or dementia]. Nederlands tijdschrift voor geneeskunde, 2007, Nov-03, Volume: 151, Issue:44 Topics: Aged; Aging; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cognition; Dementia; Dihydropyridines; Humans; Hypertension	2007
Effective management of hypertension with dihydropyridine calcium channel blocker-based combination therapy in patients at high cardiovascular risk. International journal of clinical practice, 2008, Volume: 62, Issue:5 Topics: Calcium Channel Blockers; Dihydropyridines; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Hypertension; Practice Guidelines as Topic	2008
Microcirculatory actions and uses of naturally-occurring (magnesium) and novel synthetic calcium channel blockers. Microcirculation, endothelium, and lymphatics, 1984, Volume: 1, Issue:2 Topics: Anesthesia; Animals; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Cerebrovascular Circulation; Cerebrovascular Disorders; Coronary Disease; Diabetes Mellitus; Dihydropyridines; Female; Humans; Hypertension; Ketamine; Magnesium; Magnesium Deficiency; Microcirculation; Muscle, Smooth, Vascular; Muscles; Nifedipine; Nisoldipine; Nitrendipine; Nutritional Requirements; Pentobarbital; Pre-Eclampsia; Pregnancy; Pyridines; Rats; Vasoconstrictor Agents; Vasodilator Agents; Venules	1984
Short acting dihydropyridine (vasodilating) calcium channel blockers for hypertension: is there a risk? BMJ (Clinical research ed.), 1996, May-04, Volume: 312, Issue:7039 Topics: Calcium Channel Blockers; Case-Control Studies; Clinical Trials as Topic; Dihydropyridines; Humans; Hypertension; Myocardial Ischemia; Nifedipine; Sensitivity and Specificity	1996
Complementary actions and risk reduction: the rationale for combination of an angiotensin converting enzyme inhibitor with a non-dihydropyridine calcium antagonist. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1997, Volume: 15, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Clinical Trials as Topic; Dihydropyridines; Drug Therapy, Combination; Humans; Hypertension	1997
Pharmacological profile of barnidipine: a single optical isomer dihydropyridine calcium antagonist. Blood pressure. Supplement, 1998, Volume: 1 Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Dogs; Guinea Pigs; Hypertension; Nifedipine; Rats; Rats, Inbred SHR; Structure-Activity Relationship	1998
Dihydropyridine calcium-channel blockers for the treatment of hypertensive diabetic patients. European heart journal, 2000, Volume: 21, Issue:1 Topics: Amlodipine; Calcium Channel Blockers; Diabetic Angiopathies; Dihydropyridines; Enalapril; Fosinopril; Humans; Hypertension; Randomized Controlled Trials as Topic	2000
Laragh's lessons in pathophysiology and clinical pearls for treating hypertension. American journal of hypertension, 2001, Volume: 14, Issue:9 Pt 1 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Cardiology; Dihydropyridines; Drug Therapy, Combination; Education, Medical, Continuing; Heart Diseases; Humans; Hypertension; Nitroprusside; Renin; Renin-Angiotensin System; Vasoconstriction	2001
Angiotensin converting enzyme inhibition and dihydropyridine calcium channel blockade in the treatment of left ventricular hypertrophy in arterial hypertension. Minerva cardioangiologica, 2002, Volume: 50, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Dihydropyridines; Disease Models, Animal; Diuretics; Drug Therapy, Combination; Enalapril; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Meta-Analysis as Topic; Nifedipine; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium Chloride Symporter Inhibitors; Time Factors; Ventricular Dysfunction, Left	2002

Trials

13 trial(s) available for 1,4-dihydropyridine and Hypertension

Article	Year
Effects of combination of perindopril, indapamide, and calcium channel blockers in patients with type 2 diabetes mellitus: results from the Action In Diabetes and Vascular Disease: Preterax and Diamicron Controlled Evaluation (ADVANCE) trial. Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2 Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Combinations; Drug Therapy, Combination; Female; Gliclazide; Humans; Hypertension; Hypoglycemic Agents; Indapamide; Male; Middle Aged; Perindopril; Proportional Hazards Models	2014
Rationale, study design and implementation of the COLM study: the combination of OLMesartan and calcium channel blocker or diuretic in high-risk elderly hypertensive patients. Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:2 Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Diuretics; Double-Blind Method; Drug Therapy, Combination; Endpoint Determination; Female; Humans; Hypertension; Imidazoles; Japan; Male; Prospective Studies; Risk; Tetrazoles	2009
Heart rate in hypertensive patients treated with ACE inhibitors and long-acting dihydropyridine calcium antagonists. Journal of cardiovascular pharmacology, 2002, Volume: 40, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged	2002
Effects of immediate versus delayed antihypertensive therapy on outcome in the Systolic Hypertension in Europe Trial. Journal of hypertension, 2004, Volume: 22, Issue:4 Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus; Dihydropyridines; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Enalapril; Europe; Female; Follow-Up Studies; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Incidence; Linear Models; Male; Myocardial Infarction; Nitrendipine; Stroke; Survival Rate; Time Factors; Treatment Outcome	2004
BENEDICT in the treatment of hypertension. Current hypertension reports, 2005, Volume: 7, Issue:2 Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Creatinine; Diabetes Mellitus, Type 2; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Glycated Hemoglobin; Humans; Hypertension; Indoles; Treatment Outcome; Verapamil	2005
The relationship between magnitude of proteinuria reduction and risk of end-stage renal disease: results of the African American study of kidney disease and hypertension. Archives of internal medicine, 2005, Apr-25, Volume: 165, Issue:8 Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Black or African American; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Disease Progression; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hypertension; Kidney Failure, Chronic; Male; Metoprolol; Middle Aged; Prognosis; Proteinuria; Ramipril; Risk Factors; Treatment Outcome; United States	2005
Randomized study of angiotensin II type 1 receptor blocker vs dihydropiridine calcium antagonist for the treatment of paroxysmal atrial fibrillation in patients with hypertension. Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:10 Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Atrial Fibrillation; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Dihydropyridines; Humans; Hypertension; Secondary Prevention; Tetrazoles	2006
[Hypotensive efficacy and tolerability of combination of dihydropyridine and non-dihydropyridine calcium antagonists in the treatment of patients with arterial hypertension]. Kardiologiia, 2007, Volume: 47, Issue:11 Topics: Adult; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Nifedipine; Obesity; Treatment Outcome; Verapamil	2007
Losartan potassium as initial therapy in patients with severe hypertension. Journal of human hypertension, 1995, Volume: 9, Issue:11 Topics: Adolescent; Adult; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Biphenyl Compounds; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Renin-Angiotensin System; Tetrazoles; Treatment Outcome	1995
Power spectral analysis of the heart rate in hypertensive patients with and without left ventricular hypertrophy: the effect of a left ventricular mass reduction. Journal of hypertension, 1998, Volume: 16, Issue:11 Topics: Adolescent; Adult; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Dihydropyridines; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Heart Rate; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Organ Size	1998
Systolic Hypertension in Europe (Syst-Eur) trial phase 2: objectives, protocol, and initial progress. Systolic Hypertension in Europe Investigators. Journal of human hypertension, 1999, Volume: 13, Issue:2 Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Dihydropyridines; Drug Administration Schedule; Drug Therapy, Combination; Enalapril; Europe; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Nifedipine; Prognosis; Survival Rate; Treatment Outcome	1999
The effect of pravastatin on renal function and lipid metabolism in patients with renal dysfunction with hypertension and hyperlipidemia. Pravastatin and Renal Function Research Group. Clinical and experimental hypertension (New York, N.Y. : 1993), 1999, Volume: 21, Issue:8 Topics: Blood Urea Nitrogen; Calcium Channel Blockers; Cholesterol; Creatinine; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Kidney Diseases; Male; Middle Aged; Pravastatin; Treatment Outcome	1999
Dihydropyridine calcium-channel blockers for antihypertensive treatment in older patients--evidence from the Systolic Hypertension in Europe Trial. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2001, Volume: 91, Issue:12 Topics: Aged; Alcohol Drinking; Calcium Channel Blockers; Cardiovascular Diseases; Dihydropyridines; Double-Blind Method; Europe; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Prognosis; Smoking; Treatment Outcome	2001

Other Studies

33 other study(ies) available for 1,4-dihydropyridine and Hypertension

Article	Year
Magnitude of and Characteristics Associated With the Treatment of Calcium Channel Blocker-Induced Lower-Extremity Edema With Loop Diuretics. JAMA network open, 2019, 12-02, Volume: 2, Issue:12 Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cohort Studies; Dihydropyridines; Drug Therapy, Combination; Edema; Female; Humans; Hypertension; Leg; Male; Middle Aged; Young Adult	2019
Comparison of lercanidipine plus hydrochlorothiazide vs. lercanidipine plus enalapril on micro and macrocirculation in patients with mild essential hypertension. Internal and emergency medicine, 2017, Volume: 12, Issue:7 Topics: Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged	2017
Evidence-based triple antihypertensive therapy yields lower mortality in older patients with diabetes mellitus. Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2 Topics: Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Combinations; Female; Gliclazide; Humans; Hypertension; Indapamide; Male; Perindopril	2014
Activation of the phosphatidylinositol 3-kinase pathway plays important roles in reduction of cerebral infarction by cilnidipine. Journal of neurochemistry, 2015, Volume: 135, Issue:1 Topics: Animals; Brain; Cerebral Infarction; Dihydropyridines; Disease Models, Animal; Hypertension; Male; Phosphatidylinositol 3-Kinases; Rats, Sprague-Dawley; Signal Transduction	2015
Relationship between calcium channel blocker class and mortality in dialysis. Pharmacoepidemiology and drug safety, 2015, Volume: 24, Issue:12 Topics: Calcium Channel Blockers; Cohort Studies; Comorbidity; Dihydropyridines; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Medicaid; Medicare; Middle Aged; Renal Dialysis; Retrospective Studies; Survival Analysis; United States	2015
[The Effectiveness of Combination Antihypertensive Therapy in Women With Hypothyroidism and the Metabolic Syndrome]. Kardiologiia, 2016, Volume: 56, Issue:9 Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dihydropyridines; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Hypothyroidism; Imidazoles; Losartan; Metabolic Syndrome; Middle Aged	2016
Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers. Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:4 Topics: Aged; Alleles; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Female; Humans; Hypertension; Male; Middle Aged; Polymorphism, Single Nucleotide	2009
Delayed diagnosis of primary hyperaldosteronism. BMJ (Clinical research ed.), 2010, May-25, Volume: 340 Topics: Adult; Aldosterone; Calcium Channel Blockers; Delayed Diagnosis; Dihydropyridines; Drug Resistance; Female; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Male; Middle Aged; Potassium; Renin	2010
Dihydropyridine calcium channel blockers and the progression of parkinsonism. Annals of neurology, 2012, Volume: 71, Issue:3 Topics: Aged; Aged, 80 and over; Calcium Channel Blockers; Cohort Studies; Dihydropyridines; Disease Progression; Female; Humans; Hypertension; Male; Parkinsonian Disorders; Retrospective Studies	2012
Characteristics of treated hypertension in incident hemodialysis and peritoneal dialysis patients. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 42, Issue:6 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Cause of Death; Cohort Studies; Comorbidity; Diabetes Mellitus; Dihydropyridines; Drug Prescriptions; Drug Utilization; Female; Humans; Hypertension; Kidney Failure, Chronic; Logistic Models; Lung Diseases; Male; Middle Aged; Peritoneal Dialysis; Prospective Studies; Renal Dialysis	2003
The SYST-EUR study and beyond: immediate versus delayed treatment of isolated systolic hypertension. Journal of hypertension, 2004, Volume: 22, Issue:4 Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Europe; Follow-Up Studies; Humans; Hypertension; Randomized Controlled Trials as Topic; Stroke; Survival Rate	2004
Case studies in hypertension. Dihydropyridine/nondihydropyridine calcium channel blocker combination therapy. Journal of clinical hypertension (Greenwich, Conn.), 2005, Volume: 7, Issue:1 Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Drug Therapy, Combination; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Nifedipine; Verapamil	2005
The effect of ionizing radiation of 1,4-dihydropyridine derivatives in the solid state. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2007, Volume: 67, Issue:1 Topics: Calcium Channel Blockers; Dihydropyridines; Electron Spin Resonance Spectroscopy; Felodipine; Gamma Rays; Humans; Hypertension; Models, Molecular; Molecular Conformation; Myocardial Ischemia; Nifedipine; Nimodipine	2007
Novel 2-amino-1,4-dihydropyridine calcium antagonists. I. Synthesis and antihypertensive effects of 2-amino-1,4-dihydropyridine derivatives having nitroxy-alkoxycarbonyl groups at 3- and/or 5-position. Chemical & pharmaceutical bulletin, 1995, Volume: 43, Issue:5 Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Hypertension; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred SHR; Structure-Activity Relationship	1995
Novel 2-amino-1,4-dihydropyridine calcium antagonists. II. Synthesis and antihypertensive effects of 2-amino-1,4-dihydropyridine derivatives having N,N-dialkylaminoalkoxycarbonyl groups at 3- and/or 5-position. Chemical & pharmaceutical bulletin, 1995, Volume: 43, Issue:5 Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Hypertension; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred SHR; Structure-Activity Relationship	1995
Effects of tetrandrine on left ventricle hypertrophy in deoxycorticosterone acetate-salt hypertensive rats. European journal of pharmacology, 1995, May-04, Volume: 278, Issue:1 Topics: Alkaloids; Animals; Antihypertensive Agents; Benzylisoquinolines; Binding, Competitive; Blood Pressure; Body Weight; Calcium; Desoxycorticosterone; Dihydropyridines; Disease Models, Animal; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Isradipine; Male; Mitochondria, Heart; Organ Size; Radioligand Assay; Random Allocation; Rats; Rats, Sprague-Dawley	1995
[Comment on the information by the Federal Drug and Medical Products Institute on "calcium channel blockers of the 1,4-dihydropyridine class"]. Der Internist, 1995, Volume: 36, Issue:7 Topics: Calcium Channel Blockers; Coronary Disease; Delayed-Action Preparations; Dihydropyridines; Drug Approval; Germany; Humans; Hypertension; Structure-Activity Relationship	1995
Hemodynamic and electrophysiologic effects of first- and second-generation calcium antagonists. The American journal of cardiology, 1994, Jan-27, Volume: 73, Issue:3 Topics: Amlodipine; Calcium Channel Blockers; Cardiac Output; Dihydropyridines; Electrophysiology; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Myocardial Contraction; Myocardial Ischemia; Ventricular Function, Left	1994
Calcium channel blockers. Lessons learned from MIDAS and other clinical trials. JAMA, 1996, Sep-11, Volume: 276, Issue:10 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteriosclerosis; Calcium Channel Blockers; Cardiovascular Diseases; Clinical Trials as Topic; Confounding Factors, Epidemiologic; Dihydropyridines; Humans; Hypertension	1996
1,4-Dihydropyridines versus beta-blockers for hypertension: are either safe for the heart? Cardiovascular drugs and therapy, 1996, Volume: 10, Issue:4 Topics: Adrenergic beta-Antagonists; Adult; Aged; Calcium Channel Blockers; Coronary Disease; Dihydropyridines; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Sympathetic Nervous System	1996
Sympathetic modulation of the effect of nifedipine on myocardial contraction and Ca current in the rat. Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:2 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Heart Ventricles; Hypertension; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardial Reperfusion; Nifedipine; Patch-Clamp Techniques; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Sympatholytics; Sympathomimetics; Ventricular Function	1997
Arterial responses in vitro and plasma digoxin immunoreactivity after losartan and enalapril treatments in experimental hypertension. Pharmacology & toxicology, 2000, Volume: 86, Issue:1 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Cardiomegaly; Digoxin; Dihydropyridines; Enalapril; Heart; Hypertension; Losartan; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Organ Size; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium-Potassium-Exchanging ATPase; Tunica Media	2000
Managing hypertension in patients with renal disease and diabetes. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2000, May-30, Volume: 162, Issue:11 Topics: Calcium Channel Blockers; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Dihydropyridines; Humans; Hypertension	2000
Managing hypertension in patients with renal disease and diabetes. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2000, May-30, Volume: 162, Issue:11 Topics: Calcium Channel Blockers; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Dihydropyridines; Humans; Hypertension	2000
Influence of treatment with Ca(2+) antagonists on cerebral vasculature of spontaneously hypertensive rats. Mechanisms of ageing and development, 2001, Volume: 122, Issue:8 Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain; Calcium Channel Blockers; Cerebrovascular Circulation; Dihydropyridines; Hydralazine; Hypertension; Male; Nimodipine; Nitrobenzenes; Piperazines; Rats; Rats, Inbred SHR; Rats, Wistar	2001
Dihydropyridine calcium channel blockers and peripheral side effects. Journal of human hypertension, 2001, Volume: 15, Issue:10 Topics: Calcium Channel Blockers; Dihydropyridines; Edema; Erythema; Exanthema; Humans; Hyperpigmentation; Hypertension; Male; Middle Aged; Nifedipine	2001
Role of dihydropyridine-sensitive calcium channels in the regulation of norepinephrine release in hypertension. Journal of cardiovascular pharmacology, 2001, Volume: 38 Suppl 1 Topics: Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Dose-Response Relationship, Drug; Hypertension; Male; Mesenteric Arteries; Nicardipine; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY	2001
Prevention of stroke and brain damage with calcium antagonists in animals. American journal of hypertension, 1991, Volume: 4, Issue:2 Pt 2 Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain Damage, Chronic; Calcium Channel Blockers; Cerebrovascular Disorders; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Isradipine; Male; Prognosis; Pyridines; Rats; Rats, Inbred SHR	1991
Decreased [3H]nitrendipine binding in the brainstem of deoxycorticosterone-NaCl hypertensive rats. Life sciences, 1985, Sep-09, Volume: 37, Issue:10 Topics: Animals; Brain Stem; Calcium; Desoxycorticosterone; Dihydropyridines; Hypertension; Ion Channels; Kidney; Kinetics; Male; Myocardium; Nephrectomy; Nifedipine; Nitrendipine; Organ Size; Pyridines; Rats; Sodium Chloride	1985
Renal effects of 1,4-dihydropyridines in animal models of hypertension and renal failure. Journal of cardiovascular pharmacology, 1987, Volume: 9 Suppl 1 Topics: Acute Kidney Injury; Animals; Calcium Channel Blockers; Creatinine; Dihydropyridines; Diuretics; Hypertension; Kidney; Male; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Renin	1987
Characterization of dihydropyridine binding sites in the rat brain: hypertension and age-dependent modulation of [3H](+)-PN 200-110 binding. Brain research, 1987, May-26, Volume: 412, Issue:1 Topics: Aging; Animals; Binding Sites; Brain; Calcium Channel Blockers; Dihydropyridines; Hypertension; Isradipine; Male; Oxadiazoles; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Tritium	1987
Atrial natriuretic peptide in human essential hypertension. Mayo Clinic proceedings, 1987, Volume: 62, Issue:9 Topics: Adult; Aged; Atrial Natriuretic Factor; Blood Pressure; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Ketanserin; Male; Middle Aged; Nitrendipine; Pyridines	1987
Quantitative relationships between structure and microsomal oxidation rate of 1,4-dihydropyridines. Chemico-biological interactions, 1986, Volume: 58, Issue:3 Topics: Animals; Antihypertensive Agents; Biotransformation; Dihydropyridines; Dogs; Half-Life; Hypertension; Male; Microsomes, Liver; Molecular Conformation; Oxidation-Reduction; Pyridines; Rats; Rats, Mutant Strains; Structure-Activity Relationship	1986