Page last updated: 2024-08-21

hydrazine and Hypertension

hydrazine has been researched along with Hypertension in 119 studies

Research

Studies (119)

Timeframe	Studies, this research(%)	All Research%
pre-1990	84 (70.59)	18.7374
1990's	15 (12.61)	18.2507
2000's	13 (10.92)	29.6817
2010's	7 (5.88)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Du, Z; Sun, H; Sun, P; Zhang, W	1
Kobayashi, J; Kobayashi, M; Kubo, Y; Natsume, H; Ohtake, K; Sonoda, K; Uchida, H; Uchida, M	1
Flavahan, NA; Flavahan, S; Leung, SW; Vanhoutte, PM; Xu, A; Zhao, Y	1
Alonso, MJ; Briones, AM; Cogolludo, AL; Padilha, AS; Pérez-Vizcaino, F; Salaices, M; Vassallo, DV	1
Bansal, R; Carron, R; de la Calle, C; Kumar, D	1
Graham, DA; Rush, JW	1
Butcher, JT; Frisbee, JC; Goodwill, AG; Olfert, IM	1
Llorens, S; Mendizábal, Y; Nava, E	1
Ackermann, TF; Beier, N; Boini, KM; Fuchss, T; Lang, F; Scholz, W	1
Anrather, J; Burmeister, MA; Cao, X; Davisson, RL; Guruju, MR; Iadecola, C; Peterson, JR; Wang, G; Young, CN	1
Alonso, MJ; Briones, AM; Hernanz, R; Salaices, M; Tovar, S; Vila, E	1
Abram, SR; Alexander, BT; Crell, A; Granger, JP; Llinás, MT; Seedek, M	1
DEMEULENAERE, L	1
LATTANZI, A; PANICHI, S	1
AVRIL, P; BENYAMINE, R	1
CORCORAN, AC; MASSON, GM; PAGE, IH	1
GILLESPIE, L; SJOERDSMA, A; TERRY, LL	1
ABAZA, A; RUTLISBERGER, PA	1
ABITBOL, L; PEREIRA, AF; VILLELA, AA	1
CIOBANU, V; VELICAN, D	1
CAMPUS, S; DE MARTINIS, C; FERUGLIO, FS	1
GALICER, RF	1
GRIFFITH, GC; OBLATH, RW	1
STEINHOFF, H	1
UDENFRIEND, S	1
SCHULTZ, FB	1
DAVIS, RA; DRAIN, DJ; HORLINGTON, M; LAZARE, R; URBANSKA, A	1
NATOFF, IL	1
MONTANDON, A	1
GOLDBERG, LI	1
HANY, A; NAGER, F; SCHAUB, F; SCHEITLIN, W; VOELLM, K	1
BLACKWELL, B; MABBITT, LA; MARLEY, E	1
HOBBS, LF	1
ORVIS, HH; TAMAGNA, IG; THOMAS, RE	1
Alonso, MJ; Briones, AM; Hernanz, R; Salaices, M; Vila, E	1
Feletou, M; Jensen, BL; Leung, GP; Man, RY; Skott, O; Tang, EH; Vanhoutte, PM	1
Traverso, JJ; Whitehead, CW; Willard, PW	1
Bianchini, C; Leonetti, G; Sala, C; Terzoli, L; Zanchetti, A	1
Radwan, M; Wijsenbeek, H; Zemishlany, Z	1
Colliard, M; Michelet, A; Tcherdakoff, P	1
Cybulska, I	1
Kedrowa, S; Kolber-Postepska, B; Kudlicki, J; Markiewicz, M	1
Dorigotti, L; Semeraro, C	1
Huang, A; Koller, A; Sun, D	2
Goldstein, DS; Jakab, G; Kopin, IJ; Lenders, JW; Pacák, K; Yadid, G	1
Taddei, S; Vanhoutte, PM	1
Rapoport, RM; Williams, SP	1
Brisac, AM; Champeroux, P; Safar, M; Zerrouk, A	1
Huang, A; Koller, A	1
Devynck, MA; Kunes, J; Mazeaud, MM; Zicha, J	1
Baena, AB; García-Cohen, EC; González, R; Marín, J; Rodríguez-Martínez, MA; Salaíces, M	1
Sekiguchi, F; Shimamura, K; Sunano, S; Tanaka, S; Watanabe, H	1
Hong, D; Ikezaki, H; Rubinstein, I; Suzuki, H	1
Behrends, S; Huser, L; Jacke, K; Lemmer, B; Witte, K	1
Abe, Y; Chen, QH; Kosaka, H; Tian, RX; Yamamoto, A; Yoneyama, H; Zhang, L; Zhou, MS	1
Abeywardena, MY; Head, RJ	1
Gao, YJ; Lee, RM	1
Angelino, PF; Carnovali, M; Lavezzaro, G	1
Bertel, O; Bolli, P; Bühler, FR; Kiowski, W; van Brummelen, P	1
Cronin, BL; Ludden, CT; Porter, CC; Scriabine, A; Stone, CA; Sweet, CS; Ulm, EH; Watkins, CJ; Wurtman, RJ	1
Gierlichs, HW; Hawlina, A; Planz, G; Planz, R; Rahn, KH; Stephany, W	1
Doyle, AE; Jarrott, B; Louis, WJ; McNeil, JJ; Vajda, FJ	1
Leigh, H	1
Dorigotti, L; Parravicini, F; Pifferi, G; Scarpitta, G	1
Czitober, H; Reiterer, W	1
Bianchini, C; Cornelli, U; Leonetti, G; Sala, C; Terzoli, L; Zanchetti, A	1
Hata, S; Kunida, H; Yoshioka, M	1
Rampton, DS	1
Markiewicz, M	2
Ludden, CT; Scriabine, A; Stone, CA; Watkins, CJ; Wurtman, RJ	1
Abbondati, G; Frisoni, B; Ripa, R; Tripodi, G	1
Abbondati, G; Farabegoli, E; Frisoni, B; Ripa, R; Tripodi, G	1
Harrison, T; Sisca, TS; Wood, WH	1
Diederich, A; Diederich, D; Fu-Xiang, D; Jameson, M; Skopec, J	1
Mayhan, WG	1
Lin, L; Nasjletti, A	1
Lin, L; Mistry, M; Nasjletti, A; Stier, CT	1
Mistry, M; Nasjletti, A	3
Mistry, M; Muirhead, EE; Nasjletti, A; Yamaguchi, Y	1
Woods, LL	1
Kaldunski, ML; Mattson, DL; Mistry, M; Nasjletti, A; Roman, RJ	1
Berridge, TL; Doxey, JC; Gadie, B; Myers, M; Nelson, AJ; Pape, R; Saville, JF; Turner, S	1
Denoroy, L; Fety, R; Renaud, B; Sassard, J; Tappaz, ML; Vincent, M	1
Smits, JF; Struyker-Boudier, HA	1
Beever, IA; Blair, IA; Brodie, MJ; Clare, RA; Dollery, CT; Mansilla Tinoco, R; Timbrell, JA	1
Hornsveld, R; Nievelstein, HM; Smits, JF; Struyker-Boudier, HA; van Essen, H	1
Cholewa, M; Górski, L; Markiewicz, K	1
Fournier, A; Lagrue, G; Schmitt, H	1
Albrecht, I	1
Birkmayer, W	1
Henning, M	1
Robson, RD	1
Takasak, K	1
Batson, HM; Birchall, R; Weber, GF	1
Cottier, P	1
Cagli, V; Lentini, S	1
Hitzenberger, G	1
Bessler, H; Djaldetti, M; Lewinski, U; Mandel, EM	1
Akashi, A; Chiba, T; Kasahara, A	1
Ho, BT	1
Froment, A; Milon, H	1
Gamski, M	1
Baldoli, E; Bianchi, G; Capellini, M; Dezulian, V; Sardi, A	1
Cohen, Y; Jacquot, C; Rapin, J; Wepierre, J	1
Sundermann, A	1
Day, MD; Roach, AG; Whiting, RL	1
Bravo, EL; Dustan, HP; Tarazi, RC	1
Louis, WJ; Sjoerdsma, A; Spector, S; Tabei, R	1
Aramaki, Y; Kikuchi, K; Nagaoka, A	1
Mangano, D	1
Kopin, IJ; Parks, LC; Watanabe, AM	1
Dalla Volta, S	1
Kayaalp, SO; Kaymakçalan, S; Ozer, A	1
Anfossi, F; Guaraggi, A; Rossi, PL	1

Reviews

5 review(s) available for hydrazine and Hypertension

Article	Year
MONOAMINE OXIDASE INHIBITORS. ADVERSE REACTIONS AND POSSIBLE MECHANISMS. JAMA, 1964, Nov-02, Volume: 190 Topics: Amphetamine; Amphetamines; Chemical and Drug Induced Liver Injury; Headache; Hematologic Diseases; Hepatitis; Hydrazines; Hypertension; Hypotension; Hypotension, Orthostatic; Isocarboxazid; Monoamine Oxidase Inhibitors; Nialamide; Optic Atrophy; Pargyline; Phenelzine; Sympathomimetics; Toxicology; Tranylcypromine	1964
[THE CURRENT STATUS OF THE TREATMENT OF HYPERTENSION]. Schweizerische medizinische Wochenschrift, 1964, Jun-13, Volume: 94 Topics: Antihypertensive Agents; Diet, Sodium-Restricted; Diuretics; Drug Therapy; Hydrazines; Hypertension; Mineralocorticoid Receptor Antagonists; Mortality; Prognosis; Rauwolfia; Toxicology	1964
Monoamine oxidase inhibitors--current status. The Israel journal of psychiatry and related sciences, 1983, Volume: 20, Issue:3 Topics: Antidepressive Agents, Tricyclic; Brain Chemistry; Catecholamines; Chemical Phenomena; Chemistry; Clorgyline; Depressive Disorder; Drug Interactions; Humans; Hydrazines; Hypertension; Kinetics; Monoamine Oxidase Inhibitors; Phobic Disorders; Receptors, Adrenergic; Receptors, Serotonin; Selegiline; Tyramine	1983
Studies on the mode of action of alpha-methyldopa. Acta physiologica Scandinavica. Supplementum, 1969, Volume: 322 Topics: Aminocaproates; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain Chemistry; Catecholamines; Hydrazines; Hypertension; Injections; Methyldopa; Methyltyrosines; Muscles; Myocardium; Neurons; Propionates; Rats; Reserpine; Sympathetic Nervous System; Synaptic Transmission; Time Factors	1969
Monoamine oxidase inhibitors. Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:6 Topics: Amines; Animals; Benzyl Compounds; Brain; Cattle; Dogs; Guinea Pigs; Hydrazines; Hydroxylamines; Hypertension; Indoles; Liver; Mitochondria; Mitochondria, Liver; Monoamine Oxidase Inhibitors; Pyridines; Rats; Structure-Activity Relationship; Tranylcypromine	1972

Trials

9 trial(s) available for hydrazine and Hypertension

Article	Year
Dose-response curve and time course of the antihypertensive effect of SKF 92 657, a beta-receptor-blocking and vasodilating compound. Clinical science (London, England : 1979), 1980, Volume: 59 Suppl 6 Topics: Adrenergic beta-Antagonists; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Hydrazines; Hypertension; Male; Middle Aged; Posture; Pyridazines; Time Factors; Vasodilator Agents	1980
[Treatment of severe arterial hypertension with propyldazine (ISF 2123) associated with a diuretic and a beta-blocking agent]. Minerva cardioangiologica, 1979, Volume: 27, Issue:3 Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypertension; Male; Middle Aged; Pyridazines; Vasodilator Agents	1979
Antihypertensive efficacy of a new long acting hydralazine like vasodilator, ISF 2469 in combination with a betablocker and a diuretic. International journal of clinical pharmacology and biopharmacy, 1979, Volume: 17, Issue:10 Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrazines; Hypertension; Male; Middle Aged; Prazosin; Pyridazines; Vasodilator Agents	1979
Influence of the decarboxylase inhibitor benserazide on the antihypertensive effect and metabolism of alpha-methyldopa in patients with essential hypertension. European journal of clinical pharmacology, 1977, Dec-02, Volume: 12, Issue:4 Topics: Adult; Benserazide; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Female; Humans; Hydrazines; Hypertension; Male; Methyldopa; Middle Aged; Placebos	1977
The combined use of L-alpha-methyldopa hydrazine and methyldopa in the treatment of hypertension. Clinical and experimental pharmacology & physiology. Supplement, 1978, Volume: 4 Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypertension; Levodopa; Male; Methyldopa; Middle Aged; Placebos; Time Factors	1978
Self-control, biofeedback, and change in 'psychosomatic' approach. Psychotherapy and psychosomatics, 1978, Volume: 30, Issue:3-4 Topics: Adult; Biofeedback, Psychology; Blood Pressure; Chlordiazepoxide; Clinical Trials as Topic; Female; Humans; Hydrazines; Hypertension; Male; Middle Aged; Placebos; Psychophysiologic Disorders; Relaxation Therapy	1978
[Antihypertensive effects of ecarazine hydrochloride in essential hypertension and its action on the renin-aldosterone system]. Horumon to rinsho. Clinical endocrinology, 1976, Volume: 24, Issue:9 Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Clinical Trials as Topic; Female; Heterocyclic Compounds; Humans; Hydrazines; Hypertension; Male; Middle Aged; Pyridazines; Renin	1976
[10 years of L-DOPA therapy of Parkinson's syndrome]. Wiener klinische Wochenschrift, 1971, Apr-02, Volume: 83, Issue:13 Topics: Administration, Oral; Amphetamine; Animals; Brain Chemistry; Catecholamines; Clinical Trials as Topic; Cognition Disorders; Constipation; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Feeding and Eating Disorders; Hallucinations; Humans; Huntington Disease; Hydrazines; Hypertension; Infusions, Parenteral; Injections, Intravenous; Monoamine Oxidase Inhibitors; Movement Disorders; Nausea; Norepinephrine; Parkinson Disease; Serotonin; Stimulation, Chemical; Time Factors; Tremor; Vomiting	1971
Effects of treatment on morbidity in hypertension. Results in patients with diastolic blood pressures averaging 115 through 129 mm Hg. JAMA, 1967, Dec-11, Volume: 202, Issue:11 Topics: Adult; Aged; Blood Pressure Determination; Clinical Trials as Topic; Female; Follow-Up Studies; Humans; Hydrazines; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Reserpine; Statistics as Topic	1967

Other Studies

105 other study(ies) available for hydrazine and Hypertension

Article	Year
Antagonist of thromboxane A2 receptor by SQ29548 lowers DOCA-induced hypertension in diabetic rats. European journal of pharmacology, 2017, Nov-15, Volume: 815 Topics: Animals; Aorta; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone Acetate; Diabetes Mellitus, Experimental; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Male; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane A2, Prostaglandin H2	2017
Aldehyde dehydrogenase 2 partly mediates hypotensive effect of nitrite on L-NAME-induced hypertension in normoxic rat. Clinical and experimental hypertension (New York, N.Y. : 1993), 2014, Volume: 36, Issue:6 Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hydrazines; Hypertension; Male; Mitochondrial Proteins; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitroglycerin; Rats; Rats, Sprague-Dawley; Sodium Nitrite; Time Factors	2014
Elevated pressure causes endothelial dysfunction in mouse carotid arteries by increasing local angiotensin signaling. American journal of physiology. Heart and circulatory physiology, 2015, Feb-15, Volume: 308, Issue:4 Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Carotid Arteries; Endothelium, Vascular; Hydrazines; Hypertension; Indoles; Losartan; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Reactive Oxygen Species; Signal Transduction; Tetrazoles; Valine; Valsartan; Vasodilation	2015
Activation of BKCa channels by nitric oxide prevents coronary artery endothelial dysfunction in ouabain-induced hypertensive rats. Journal of hypertension, 2009, Volume: 27, Issue:1 Topics: Animals; Coronary Vessels; Endothelium, Vascular; Hydrazines; Hypertension; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Male; Nitric Oxide; Ouabain; Potassium Channels; Pyrazoles; Pyridines; Rats; Rats, Wistar; Vasodilation	2009
Synthesis and vasodilatory activity of some amide derivatives of 6-(4-carboxymethyloxyphenyl)-4,5-dihydro-3(2H)-pyridazinone. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Animals; Aorta; Female; Hydrazines; Hypertension; Male; Pyridazines; Rats; Rats, Wistar; Structure-Activity Relationship; Vasodilation; Vasodilator Agents	2009
Cyclooxygenase and thromboxane/prostaglandin receptor contribute to aortic endothelium-dependent dysfunction in aging female spontaneously hypertensive rats. Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 107, Issue:4 Topics: Acetylcholine; Age Factors; Aging; Animals; Aorta; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Fatty Acids, Unsaturated; Female; Hydrazines; Hypertension; Indomethacin; Male; Membrane Proteins; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Epoprostenol; Receptors, Thromboxane A2, Prostaglandin H2; Sex Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents	2009
Divergence between arterial perfusion and fatigue resistance in skeletal muscle in the metabolic syndrome. Experimental physiology, 2011, Volume: 96, Issue:3 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antioxidants; Arteries; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Hydrazines; Hyperemia; Hypertension; In Vitro Techniques; Male; Metabolic Syndrome; Methacholine Chloride; Muscle Fatigue; Muscle, Skeletal; Obesity; Oxygen; Perfusion; Peripheral Vascular Diseases; Phenylephrine; Rats; Rats, Zucker; Vasoconstriction	2011
Effects of pioglitazone and rosiglitazone on vascular function of mesenteric resistance arteries in rat genetic hypertension. Pharmacology, 2011, Volume: 88, Issue:1-2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endothelium, Vascular; Epinephrine; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Hypoglycemic Agents; Indomethacin; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroprusside; Pioglitazone; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rosiglitazone; Thiazolidinediones; Thromboxane A2; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents	2011
EMD638683, a novel SGK inhibitor with antihypertensive potency. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2011, Volume: 28, Issue:1 Topics: Animals; Antihypertensive Agents; Benzamides; Blood Pressure; Cell Cycle Proteins; Fructose; HeLa Cells; Humans; Hydrazines; Hypertension; Immediate-Early Proteins; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Sodium; Sodium Chloride	2011
Angiotensin II-dependent hypertension requires cyclooxygenase 1-derived prostaglandin E2 and EP1 receptor signaling in the subfornical organ of the brain. Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:4 Topics: Angiotensin II; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Hydrazines; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxazepines; Reactive Oxygen Species; Receptor Cross-Talk; Receptors, Prostaglandin E, EP1 Subtype; Signal Transduction; Subfornical Organ	2012
Hypertension alters the participation of contractile prostanoids and superoxide anions in lipopolysaccharide effects on small mesenteric arteries. Life sciences, 2002, Sep-13, Volume: 71, Issue:17 Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase 2; Dexamethasone; Dose-Response Relationship, Drug; Drug Combinations; Fatty Acids, Unsaturated; Hydrazines; Hypertension; In Vitro Techniques; Indomethacin; Isoenzymes; Lipopolysaccharides; Male; Mesenteric Arteries; Mice; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Norepinephrine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Thromboxane; Sulfonamides; Superoxide Dismutase; Thromboxane A2	2002
Enhanced thromboxane synthesis during chronic reductions in uterine perfusion pressure in pregnant rats. American journal of hypertension, 2002, Volume: 15, Issue:9 Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Fatty Acids, Unsaturated; Female; Hydrazines; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Renal Circulation; Thromboxane A2; Uterus	2002
[Experience with adelphan therapy in 25 cases of essential hypertension]. Belgisch tijdschrift voor geneeskunde, 1955, Oct-01, Volume: 11, Issue:19 Topics: Antihypertensive Agents; Essential Hypertension; Hydrazines; Hypertension; Secologanin Tryptamine Alkaloids; Sympatholytics	1955
[Effect of hydrazinophthalazine on renal circulation in arterial hypertension]. Acta medica Scandinavica. Supplementum, 1956, Volume: 312 Topics: Hydralazine; Hydrazines; Hypertension; Kidney; Renal Circulation	1956
[Modern medications of arterial hypertension. III. Treatment with derivatives of hydrazine]. Marseille medical, 1957, Volume: 94, Issue:4 Topics: Humans; Hydralazine; Hydrazines; Hypertension; Monitoring, Physiologic; Sympatholytics	1957
High arterial pressure as a primary cause of hypertensive vascular lesions. Cleveland Clinic quarterly, 1959, Volume: 26, Issue:1 Topics: Arterial Pressure; Arteries; Disease; Humans; Hydrazines; Hypertension; Vascular Diseases	1959
The application of a monoamine-oxidase inhibitor, I-phenyl-2-hydrazinopropane (JB-516), to the treatment of primary hypertension. American heart journal, 1959, Volume: 58, Issue:1 Topics: Essential Hypertension; Humans; Hydrazines; Hypertension; Monoamine Oxidase Inhibitors; Oxidoreductases; Propane	1959
[The monoamine oxidase inhibitors in cardiovascular therapeutics (angina pectoris and arterial hypertension)]. La Semaine des hopitaux: therapeutique, 1960, Volume: 36 Topics: Angina Pectoris; Cardiovascular System; Hydrazines; Hypertension; Monoamine Oxidase Inhibitors; Oxidoreductases	1960
[Clinical evaluation of Nialamide in cardiology]. Hospital (Rio de Janeiro, Brazil), 1960, Volume: 58 Topics: Angina Pectoris; Cardiology; Hydrazines; Hypertension; Neurotic Disorders; Nialamide	1960
[Hydralazine syndrome after prolonged treatment with adelphan]. Medicina interna, 1961, Volume: 13 Topics: Hydralazine; Hydrazines; Hypertension; Lupus Erythematosus, Systemic; Reserpine	1961
[On the treatment of arterial hypertension with a drug inhibiting monoamine oxidase (DL-serine-N2-isopropylhydrazide)]. La Clinica terapeutica, 1960, Volume: 19 Topics: Hydrazines; Hypertension; Monoamine Oxidase; Oxidoreductases; Serine	1960
[Treatment of pain of cardiac origin with Ro 4-1634, 1-pivaloyl-2-benzylhydrazine]. La Semana medica, 1960, Jul-28, Volume: 117 Topics: Angina Pectoris; Heart Valve Diseases; Heart Valves; Hydrazines; Hypertension; Propionates	1960
The aminase oxidase inhibitors. Their current place in clinical medicine. California medicine, 1960, Volume: 93 Topics: Angina Pectoris; Antihypertensive Agents; Hydrazines; Hypertension; Monoamine Oxidase Inhibitors; Oxidoreductases	1960
[New therapeutic methods in the treatment of hypertension]. Deutsches medizinisches Journal, 1960, Feb-20, Volume: 11 Topics: Chlorothiazide; Hydrazines; Hypertension; Reserpine	1960
Urinary tryptamine in hypertensive patients treated with JB-516 and nialamide. Diseases of the nervous system, 1959, Volume: 20(Suppl) Topics: Hydrazines; Hypertension; Isoniazid; Nialamide; Serotonin; Tryptamines	1959
A new triple combination tablet for anti-hypertensive therapy. Journal of the Medical Association of the State of Alabama, 1963, Volume: 33 Topics: Antihypertensive Agents; Hydrazines; Hydrochlorothiazide; Hypertension; Reserpine; Tablets	1963
The effect of L-alpha-methyl DOPA and N-2-hydroxybenzyl-N-methyl hydrazine (NSD 1039) on the blood pressure of renal hypertensive rates. Life sciences (1962), 1963, Volume: 3 Topics: Blood Pressure; Dihydroxyphenylalanine; Hydrazines; Hypertension; Hypertension, Renal; Kidney; Methyldopa; Methylhydrazines	1963
CHEESE AND MONOAMINE OXIDASE INHIBITORS. INTERACTION IN ANAESTHETISED CATS. Lancet (London, England), 1964, Mar-07, Volume: 1, Issue:7332 Topics: Cheese; Hydrazines; Hypertension; Imipramine; Iproniazid; Monoamine Oxidase Inhibitors; Nialamide; Pharmacology; Phenelzine; Toxicology; Tranylcypromine; Triflupromazine; Tyramine	1964
[ANTIHYPERTENSIVE PROPERTIES OF POLYTHIAZIDE]. Therapeutische Umschau. Revue therapeutique, 1963, Volume: 20 Topics: Antihypertensive Agents; Benzothiadiazines; Chlorthalidone; Diuretics; Hydrazines; Hypertension; Methyldopa; Polythiazide	1963
EFFECTS OF YEAST EXTRACT AFTER MONOAMINE-OXIDASE INHIBITION. Lancet (London, England), 1965, May-01, Volume: 1, Issue:7392 Topics: Animals; Cats; Duodenum; Guinea Pigs; Headache; Histamine; Hydrazines; Hypersensitivity; Hypertension; Hypotension; Ileum; Intestinal Absorption; Monoamine Oxidase Inhibitors; Nialamide; Nictitating Membrane; Oxidoreductases; Pharmacology; Rats; Research; Toxicology; Tranylcypromine; Tyramine; Yeasts	1965
Effect of nardil on hypertension and the anginal syndrome. Angiology, 1960, Volume: 11 Topics: Angina Pectoris; Hydrazines; Hypertension; Oxidoreductases; Phenelzine	1960
Evaluation of 2 monoamine oxidase inhibitors (iproniazid and JB 516) in the therapy of arterial hypertension. The American journal of the medical sciences, 1959, Volume: 238 Topics: Hydrazines; Hypertension; Iproniazid; Monoamine Oxidase Inhibitors	1959
Hypertension alters role of iNOS, COX-2, and oxidative stress in bradykinin relaxation impairment after LPS in rat cerebral arteries. American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:1 Topics: Animals; Bradykinin; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Arteries; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Isoenzymes; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Oxidative Stress; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Sulfonamides; Vasodilation	2004
The role of prostaglandin E and thromboxane-prostanoid receptors in the response to prostaglandin E2 in the aorta of Wistar Kyoto rats and spontaneously hypertensive rats. Cardiovascular research, 2008, Apr-01, Volume: 78, Issue:1 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta, Thoracic; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Immunohistochemistry; Naphthalenes; Phenylephrine; Potassium Chloride; Propionates; Prostaglandin Antagonists; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Thromboxane; Sulfonamides; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Xanthones	2008
Hypotensive 1,2-benzisothiazole 1,1-dioxides. 3. 3-[2-(2-Methyl-2-butylidene)hydrazino]-1,2-benzisothiazole 1,1-dioxide and related analogs. Journal of medicinal chemistry, 1967, Volume: 10, Issue:5 Topics: Animals; Antihypertensive Agents; Benzene Derivatives; Blood Circulation; Dogs; Hydrazines; Hypertension; Hypertension, Renal; Muscle, Smooth; Nictitating Membrane; Oxides; Rabbits; Rats; Sympathomimetics; Thiazoles	1967
[Treatment of certain refractory arterial hypertensions with a monoamine oxidase inhibitor]. Archives des maladies du coeur et des vaisseaux, 1981, Volume: 74 Spec No Topics: Female; Glycolates; Humans; Hydrazines; Hypertension; Male; Monoamine Oxidase Inhibitors	1981
[Phthalazine derivatives in the treatment of arterial hypertension]. Kardiologia polska, 1981, Volume: 24, Issue:10 Topics: Arterioles; Blood Pressure; Humans; Hydralazine; Hydrazines; Hypertension; Todralazine; Vasodilator Agents	1981
[Hypotensive action of binazine in the light of our studies]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1980, Mar-15, Volume: 33, Issue:6 Topics: Adult; Aged; Female; Humans; Hydrazines; Hypertension; Hypertension, Renal; Male; Middle Aged; Todralazine	1980
Renal function studies with propildazine alone and in combination with propranolol in dogs. European journal of pharmacology, 1980, Oct-17, Volume: 67, Issue:2-3 Topics: Animals; Antihypertensive Agents; Blood Pressure; Dogs; Female; Glomerular Filtration Rate; Hydrazines; Hypertension; Kidney; Propranolol; Pyridazines; Vasodilator Agents	1980
Endothelial dysfunction augments myogenic arteriolar constriction in hypertension. Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:6 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arachidonic Acid; Arterioles; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Imidazoles; In Vitro Techniques; Indomethacin; Male; Muscles; Nitroprusside; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins; Prostaglandins H; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Receptors, Thromboxane; Thromboxane A2; Thromboxane-A Synthase; Vasoconstriction; Vasoconstrictor Agents	1993
In vivo hypothalamic release and synthesis of catecholamines in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:4 Topics: Aging; Animals; Brain; Catecholamines; Catechols; Dialysis; Dihydroxyphenylalanine; Hydrazines; Hypertension; Hypothalamus; Injections; Male; Osmolar Concentration; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Yohimbine	1993
Role of endothelium in endothelin-evoked contractions in the rat aorta. Hypertension (Dallas, Tex. : 1979), 1993, Volume: 21, Issue:1 Topics: Animals; Aorta, Thoracic; Bridged Bicyclo Compounds, Heterocyclic; Endothelins; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydrazines; Hypertension; In Vitro Techniques; Indomethacin; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thromboxane B2; Vasoconstriction	1993
Role of prostaglandins in acetylcholine-induced contraction of aorta from spontaneously hypertensive and Wistar-Kyoto rats. Hypertension (Dallas, Tex. : 1979), 1996, Volume: 28, Issue:1 Topics: Acetylcholine; Analysis of Variance; Animals; Aorta; Bridged Bicyclo Compounds, Heterocyclic; Endothelium, Vascular; Epoprostenol; Fatty Acids, Unsaturated; Hydrazines; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Prostaglandins; Prostaglandins F; Prostaglandins H; Rats; Rats, Inbred F344; Rats, Inbred SHR; Rats, Inbred WKY	1996
Role of endothelium in the endothelin-1-mediated potentiation of the norepinephrine response in the aorta of hypertensive rats. Journal of hypertension, 1997, Volume: 15, Issue:10 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta, Thoracic; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase Inhibitors; Drug Synergism; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Male; Nifedipine; Norepinephrine; Oligopeptides; Peptides, Cyclic; Piperidines; Piroxicam; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Endothelin; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents	1997
Endothelin and prostaglandin H2 enhance arteriolar myogenic tone in hypertension. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:5 Topics: Animals; Arterioles; Bridged Bicyclo Compounds, Heterocyclic; Endothelins; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Male; Muscle, Smooth, Vascular; Prostaglandin H2; Prostaglandins H; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasomotor System	1997
Platelet hypoaggregability in hereditary hypertriglyceridemic rats: relation to plasma triglycerides. Thrombosis research, 1997, Nov-15, Volume: 88, Issue:4 Topics: Adenosine Diphosphate; Animals; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Hypertriglyceridemia; Kinetics; Male; Platelet Aggregation; Rats; Rats, Inbred Lew; Receptors, Thromboxane; Thrombin; Triglycerides	1997
Contractile responses elicited by hydrogen peroxide in aorta from normotensive and hypertensive rats. Endothelial modulation and mechanism involved. British journal of pharmacology, 1998, Volume: 125, Issue:6 Topics: Animals; Aorta; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Dimethyl Sulfoxide; Endothelium, Vascular; Fatty Acids, Unsaturated; Free Radical Scavengers; Hydrazines; Hydrogen Peroxide; Hypertension; In Vitro Techniques; Indomethacin; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Oxidants; Prostaglandins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Superoxide Dismutase	1998
Endothelium-derived relaxing, contracting and hyperpolarizing factors of mesenteric arteries of hypertensive and normotensive rats. British journal of pharmacology, 1999, Volume: 126, Issue:3 Topics: Acetylcholine; Animals; Apamin; Blood Pressure; Body Weight; Bridged Bicyclo Compounds, Heterocyclic; Charybdotoxin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Glyburide; Hydrazines; Hypertension; In Vitro Techniques; Indomethacin; Membrane Potentials; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Nitroprusside; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Systole; Tetraethylammonium; Vasodilation; Vasodilator Agents	1999
Shear stress-induced release of prostaglandin H(2) in arterioles of hypertensive rats. Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:4 Topics: Animals; Arterioles; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Prostaglandin H2; Prostaglandins H; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Prostaglandin; Receptors, Thromboxane A2, Prostaglandin H2; Stress, Mechanical; Thromboxane-A Synthase	2000
PGH(2)-TxA(2)-receptor blockade restores vasoreactivity in a new rodent model of genetic hypertension. Journal of applied physiology (Bethesda, Md. : 1985), 2000, Volume: 88, Issue:6 Topics: Acetylcholine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cheek; Cricetinae; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Male; Nitroglycerin; Prostaglandin H2; Prostaglandins H; Thromboxane A2; Vasoactive Intestinal Peptide; Vasodilation; Vasodilator Agents; Vasomotor System	2000
Contribution of the renin-angiotensin system to subsensitivity of soluble guanylyl cyclase in TGR(mREN2)27 rats. European journal of pharmacology, 2000, Sep-01, Volume: 403, Issue:1-2 Topics: Aging; Amlodipine; Analysis of Variance; Animals; Animals, Genetically Modified; Aorta, Thoracic; Blood Pressure; Calcium Channel Blockers; Cyclic GMP; Dose-Response Relationship, Drug; Enalapril; Guanylate Cyclase; Hydrazines; Hypertension; Male; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Solubility	2000
L-Arginine improves endothelial function in renal artery of hypertensive Dahl rats. Journal of hypertension, 2001, Volume: 19, Issue:3 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cyclic GMP; Endothelins; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydralazine; Hydrazines; Hypertension; In Vitro Techniques; Indomethacin; Male; Methacrylates; Natriuresis; Nitrates; Nitrites; Nitroprusside; Rats; Rats, Inbred Dahl; Renal Artery; Thromboxane A2; Vasoconstriction	2001
Dietary polyunsaturated fatty acid and antioxidant modulation of vascular dysfunction in the spontaneously hypertensive rat. Prostaglandins, leukotrienes, and essential fatty acids, 2001, Volume: 65, Issue:2 Topics: Acetylcholine; alpha-Tocopherol; Animals; Antioxidants; Aorta; Bridged Bicyclo Compounds, Heterocyclic; Cardiovascular Agents; Diet; Dose-Response Relationship, Drug; Endothelium, Vascular; Fatty Acids, Unsaturated; Flavonoids; Hydrazines; Hypertension; Indomethacin; Kaempferols; Lipid Metabolism; Nitric Oxide; Phthalic Acids; Plant Oils; Platelet Aggregation Inhibitors; Quercetin; Rats; Rats, Inbred SHR; Rutin; Umbelliferones	2001
Hydrogen peroxide induces a greater contraction in mesenteric arteries of spontaneously hypertensive rats through thromboxane A(2) production. British journal of pharmacology, 2001, Volume: 134, Issue:8 Topics: Animals; Aorta; Bridged Bicyclo Compounds, Heterocyclic; Culture Techniques; Dioxanes; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydrazines; Hydrogen Peroxide; Hypertension; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tachyphylaxis; Thromboxane A2; Thromboxane B2	2001
Antihypertensive activity of metyrosine in spontaneously hypertensive rats and its enhancement by carbidopa. Clinical science and molecular medicine. Supplement, 1978, Volume: 4 Topics: Animals; Blood Pressure; Brain; Carbidopa; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Hydrazines; Hypertension; Methyltyrosines; Myocardium; Norepinephrine; Rats	1978
[3-Hydrazinepyridazine derivatives. III. Synthesis and anti-hypertensive activity of new 3-(2-acylhydrazine)-pyridazine-6-alkylamino substitutes]. Il Farmaco; edizione scientifica, 1979, Volume: 34, Issue:4 Topics: Animals; Antihypertensive Agents; Hydralazine; Hydrazines; Hypertension; Pyridazines; Rats; Todralazine	1979
[The influence of guanazodine and todralazine on blood pressure regulation during dynamic and static exercise in essential hypertension (author's transl)]. Arzneimittel-Forschung, 1977, Volume: 27, Issue:11 Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Guanidines; Heart Rate; Humans; Hydrazines; Hypertension; Male; Middle Aged; Physical Exertion; Todralazine	1977
[Clinical pharmacology of a new hypotensive drug with peripheral vasodilating action (ISF 2123); effects of acute intravenous administration in hypertensive patients]. Bollettino della Societa italiana di cardiologia, 1977, Volume: 22, Issue:7 Topics: Antihypertensive Agents; Drug Evaluation; Female; Humans; Hydrazines; Hypertension; Injections, Intravenous; Male; Pyridazines; Vasodilator Agents	1977
Hypertensive crisis in a patient given sinemet, metoclopramide, and amitriptyline. British medical journal, 1977, Sep-03, Volume: 2, Issue:6087 Topics: Acute Disease; Amitriptyline; Carbidopa; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypertension; Levodopa; Metoclopramide; Middle Aged; Parkinson Disease	1977
[Value of simultaneous administration of propranolol, binazine and furosemide in the treatment of hypertension]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1977, Oct-01, Volume: 30, Issue:19 Topics: Adult; Drug Therapy, Combination; Female; Furosemide; Humans; Hydrazines; Hypertension; Male; Middle Aged; Propranolol; Todralazine	1977
Enhancement of the anti-hypertensive effect of methyldopa and other anti-hypertensive drugs by carbidopa in spontaneously hypertensive rats. Clinical science and molecular medicine. Supplement, 1976, Volume: 3 Topics: Animals; Antihypertensive Agents; Carbidopa; Catecholamines; Dose-Response Relationship, Drug; Drug Synergism; Hydrazines; Hypertension; Male; Methyldopa; Myocardium; Rats	1976
[Value of simultaneous administration of Propranolol and Binazin in the treatment of arterial hypertension]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1975, Nov-10, Volume: 30, Issue:45 Topics: Adult; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypertension; Male; Middle Aged; Propranolol; Todralazine	1975
[Activity of a new derivative of 3-hydrazinopyridazine: ISF 2123 in patients with hypertension. I]. Minerva cardioangiologica, 1975, Volume: 23, Issue:11 Topics: Aged; Drug Evaluation; Female; Humans; Hydrazines; Hypertension; Male; Middle Aged; Propanolamines; Pyridazines	1975
[Effect of a new derivative of 3-hydrazine pyridazine: ISF 2123 in hypertensive patients. Note 2]. Minerva cardioangiologica, 1975, Volume: 23, Issue:12 Topics: Adult; Aged; Drug Evaluation; Female; Humans; Hydrazines; Hypertension; Male; Middle Aged; Pyridazines	1975
Case report. Propranolol-induced lupus syndrome? Postgraduate medicine, 1976, Volume: 59, Issue:1 Topics: Humans; Hydrazines; Hypertension; Lupus Erythematosus, Systemic; Male; Middle Aged; Practolol; Propranolol; Skin Manifestations	1976
Endothelial dysfunction of resistance arteries of spontaneously hypertensive rats. Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 12 Topics: Acetylcholine; Amitrole; Animals; Bridged Bicyclo Compounds, Heterocyclic; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Indomethacin; Male; Mesenteric Arteries; Prostaglandin H2; Prostaglandins H; Rats; Rats, Inbred SHR; Renal Artery; Superoxides; Thromboxane A2; Vasodilation	1992
Role of prostaglandin H2-thromboxane A2 in responses of cerebral arterioles during chronic hypertension. The American journal of physiology, 1992, Volume: 262, Issue:2 Pt 2 Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arterioles; Brain; Bridged Bicyclo Compounds, Heterocyclic; Chronic Disease; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Imidazoles; Male; Nitroglycerin; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thromboxane A2; Vasodilator Agents	1992
Role of endothelium-derived prostanoid in angiotensin-induced vasoconstriction. Hypertension (Dallas, Tex. : 1979), 1991, Volume: 18, Issue:2 Topics: Acetylcholine; Analysis of Variance; Angiotensin II; Animals; Aorta; Aortic Coarctation; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Endothelins; Endothelium; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Imidazoles; In Vitro Techniques; Indomethacin; Isometric Contraction; Male; Phenylephrine; Prostaglandin Endoperoxides, Synthetic; Pyridines; Rats; Rats, Inbred Strains; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Vasoconstriction	1991
Role of prostanoids in renin-dependent and renin-independent hypertension. Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:4 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Male; Prostaglandins; Rats; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Prostaglandin; Renin; Thromboxane A2; Thromboxane B2	1991
Contrasting effect of thromboxane synthase inhibitors and a thromboxane receptor antagonist on the development of angiotensin II-salt-induced hypertension in rats. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:1 Topics: Angiotensin II; Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Imidazoles; Male; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Sodium Chloride; Thromboxane A2; Thromboxane-A Synthase	1990
Renal function in rats with angiotensin II-salt-induced hypertension: effect of thromboxane synthesis inhibition and receptor blockade. Journal of hypertension, 1990, Volume: 8, Issue:1 Topics: Angiotensin II; Animals; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Imidazoles; Kidney; Male; Rats; Rats, Inbred Strains; Sodium, Dietary; Thromboxane A2; Thromboxane-A Synthase; Vascular Resistance	1990
Role of TXA2 in the pathogenesis of severe angiotensin II-salt hypertension. Advances in prostaglandin, thromboxane, and leukotriene research, 1989, Volume: 19 Topics: Angiotensin II; Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Imidazoles; In Vitro Techniques; Kidney; Kidney Cortex; Muscle, Smooth, Vascular; Rats; Reference Values; Sodium, Dietary; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase	1989
Importance of prostaglandins in hypertension during reduced uteroplacental perfusion pressure. The American journal of physiology, 1989, Volume: 257, Issue:6 Pt 2 Topics: Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Dogs; Fatty Acids, Unsaturated; Female; Hydrazines; Hypertension; Ischemia; Meclofenamic Acid; ortho-Aminobenzoates; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy, Animal; Prostaglandins; Reperfusion; Thromboxane A2; Uterus	1989
Role of pressor prostanoids in rats with angiotensin II-salt-induced hypertension. Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:6 Pt 2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Arteries; Bridged Bicyclo Compounds, Heterocyclic; Dinoprost; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Imidazoles; Kidney Cortex; Male; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins F; Rats; Rats, Inbred Strains; Sodium Chloride; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase	1988
Influence of eicosanoids on renal function of DOCA-salt hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1988, Volume: 12, Issue:3 Topics: Animals; Benzofurans; Body Water; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone; Fatty Acids, Unsaturated; Hemodynamics; Hydrazines; Hypertension; Kidney; Male; Meclofenamic Acid; Prostaglandins; Rats; Rats, Inbred Strains; Renal Circulation; Sodium; Sodium Chloride; Thromboxanes	1988
Antihypertensive thiadiazoles. 1. Synthesis of some 2-aryl-5-hydrazino-1,3,4-thiadiazoles with vasodilator activity. Journal of medicinal chemistry, 1988, Volume: 31, Issue:5 Topics: Animals; Antihypertensive Agents; Blood Pressure; Decerebrate State; Hydrazines; Hypertension; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiadiazoles	1988
Rate of tryptophan hydroxylation in vivo in brain nuclei of genetically hypertensive rats of the Lyon strain. Experientia, 1985, Apr-15, Volume: 41, Issue:4 Topics: 5-Hydroxytryptophan; Aging; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Hydrazines; Hydroxylation; Hypertension; Hypothalamus; Medulla Oblongata; Raphe Nuclei; Rats; Rats, Mutant Strains; Tryptophan	1985
Preferential renal vasodilator effects of CGP 22979A in conscious spontaneously hypertensive rats. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:3 Topics: Animals; Blood Pressure; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Hindlimb; Hydralazine; Hydrazines; Hypertension; Kidney; Male; Rats; Rats, Inbred SHR; Vascular Resistance; Vasodilator Agents	1985
Plasma hydrazine concentrations in man after isoniazid and hydralazine administration. Human toxicology, 1985, Volume: 4, Issue:2 Topics: Acetylation; Adult; Gas Chromatography-Mass Spectrometry; Humans; Hydralazine; Hydrazines; Hypertension; Isoniazid; Male; Phenotype	1985
Effects of the renal vasodilator prodrug CGP 22 979A and its parent compound CGP 18 137A on renal and central hemodynamics in conscious spontaneously hypertensive rats. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3 Topics: Animals; Diuretics; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Hemodynamics; Hydrazines; Hypertension; Kidney; Male; Rats; Rats, Inbred SHR; Renal Circulation; Vasodilator Agents	1985
Post-exertion changes in left ventricular systolic time intervals in patients with primary hypertension treated with hydrochlorothiazide, binazine, and propranolol. Acta medica Hungarica, 1985, Volume: 42, Issue:3-4 Topics: Adult; Aged; Female; Heart Ventricles; Humans; Hydrazines; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Myocardial Contraction; Physical Exertion; Propranolol; Stroke Volume; Systole; Todralazine	1985
[Pharmacological basis of the symptomatic treatment of arterial hypertension. II. Antihypertensive agent combinations]. La Nouvelle presse medicale, 1973, Nov-03, Volume: 2, Issue:39 Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Ganglionic Blockers; Guanethidine; Heterocyclic Compounds; Humans; Hydrazines; Hypertension; Methyldopa; Monoamine Oxidase Inhibitors; Reserpine	1973
Critical period for the development of spontaneous hypertension in rats. Mechanisms of ageing and development, 1974, Volume: 3, Issue:1 Topics: Animals; Brain Diseases; Cardiovascular Diseases; Female; Guanethidine; Heterocyclic Compounds; Hydrazines; Hypertension; Kidney Diseases; Male; Nephrosclerosis; Pleurisy; Polyarteritis Nodosa; Pulmonary Atelectasis; Pyridazines; Rats; Sex Factors; Time Factors	1974
Modification of the cardiovascular effects of L-dopa in anesthetized dogs by inhibitors of enzymes involved in catecholamine metabolism. Circulation research, 1971, Volume: 28, Issue:6 Topics: Angiotensin II; Animals; Blood Pressure; Bradycardia; Carboxy-Lyases; Cresols; Dihydroxyphenylalanine; Dogs; Dopamine; Female; Heart Rate; Hydrazines; Hypertension; Hypotension; Male; Methyldopa; Monoamine Oxidase Inhibitors; Norepinephrine; Tachycardia; Thiocarbamates	1971
Adrenergic mechanism of the drugs. Systemic arterial pressure changes caused by intravenous injection of reserpine following the administration of pheniprazine and pyrogallol in anesthetized dogs. The Kurume medical journal, 1966, Volume: 13, Issue:3 Topics: Animals; Blood Pressure; Carotid Arteries; Dogs; Epinephrine; Hydrazines; Hypertension; Injections, Intravenous; Pyrogallol; Reserpine	1966
Hypertension: current trends in diagnosis and treatment. Geriatrics, 1967, Volume: 22, Issue:11 Topics: Aortic Coarctation; Azides; Cushing Syndrome; Ganglionic Blockers; Humans; Hydrazines; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Methyldopa; Renal Artery Obstruction; Reserpine; Trimethaphan	1967
[On the choice of hypotensive drugs with reference to their cardiac effect]. Schweizerische medizinische Wochenschrift, 1967, Dec-30, Volume: 97, Issue:52 Topics: Antihypertensive Agents; Diuretics; Ganglionic Blockers; Guanethidine; Heart; Humans; Hydrazines; Hypertension; Imidazoles; Methyldopa; Monoamine Oxidase Inhibitors; Reserpine; Triamterene	1967
[Therapy of essential arterial hypertension]. Il Policlinico. Sezione pratica, 1969, Apr-07, Volume: 76, Issue:14 Topics: Age Factors; Diet Therapy; Dihydroxyphenylalanine; Diuretics; Ganglionic Blockers; Humans; Hydrazines; Hypertension	1969
[Clinical pharmacology of hypertension]. Wiener klinische Wochenschrift, 1971, Sep-17, Volume: 83, Issue:37 Topics: Adrenergic beta-Antagonists; Blood Pressure; Bretylium Compounds; Cardiac Volume; Diuretics; Ganglionic Blockers; Guanethidine; Humans; Hydrazines; Hypertension; Imidazoles; Methyldopa; Monoamine Oxidase Inhibitors; Phytotherapy; Plants, Medicinal; Plants, Toxic; Rauwolfia; Veratrum; Water-Electrolyte Balance	1971
Inhibition of uridine incorporation in proerythroblasts patients with alpha-methyldopa induced haemolytic anaemia. British journal of haematology, 1974, Volume: 27, Issue:4 Topics: Anemia, Hemolytic; Animals; Autoradiography; Coombs Test; Erythrocytes; Female; Hematopoietic Stem Cells; Hemoglobins; Humans; Hydrazines; Hypertension; Injections, Intraperitoneal; Male; Methyldopa; Mice; Middle Aged; Osmotic Fragility; Prednisolone; Reticulocytes; Thymidine; Tritium; Uridine	1974
Antihypertensive activity of 1-(2-(1,3-dimethyl-2-butenylidene)-hydrazino)-phthalazine (DJ-1461), a new phthalazine derivative. European journal of pharmacology, 1974, Volume: 29, Issue:1 Topics: Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Heterocyclic Compounds; Hydralazine; Hydrazines; Hypertension; Phthalazines; Rats; Stimulation, Chemical; Time Factors	1974
[Medical treatment of arterial hypertension in adults]. La Revue du praticien, 1973, Feb-11, Volume: 23, Issue:9 Topics: Adult; Antihypertensive Agents; Clonidine; Diet, Sodium-Restricted; Guanethidine; Humans; Hydrazines; Hypertension; Male; Methyldopa; Reserpine; Spironolactone; Time Factors	1973
[Binazine--a new phthalazine derivative]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1973, Aug-01, Volume: 28, Issue:15 Topics: Antihypertensive Agents; Carboxylic Acids; Chlorothiazide; Heterocyclic Compounds; Humans; Hydrazines; Hypertension; Phytotherapy; Plants, Medicinal; Pyridazines; Rauwolfia	1973
Onthe pharmacology of 3-hydrazino-6-(N,N-bis(2-hydroxyethyl)amino)-pyridazine-dihydrochloride (L 6150). Arzneimittel-Forschung, 1973, Volume: 23, Issue:11 Topics: Animals; Blood Pressure; Cardiac Output; Decerebrate State; Dogs; Ethanolamines; Female; Hydralazine; Hydrazines; Hypertension; Lethal Dose 50; Male; Mice; Pyridazines; Rabbits; Rats; Spinal Cord; Time Factors	1973
[Relationship between the antihypertensive activity of methyldopa and the appearance of its metabolites in the heart and brain of the hypertensive rat]. Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 207, Issue:2 Topics: Animals; Antihypertensive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Biotransformation; Blood Pressure; Brain; Disulfides; Disulfiram; Dopamine; Dopamine beta-Hydroxylase; Hydrazines; Hypertension; Imidazoles; Male; Methane; Methyldopa; Myocardium; Norepinephrine; Rats; Sympatholytics; Time Factors; Tritium	1974
[Current treatment of cardiovascular diseases with special reference to long-term therapy]. Zeitschrift fur arztliche Fortbildung, 1967, Jun-15, Volume: 61, Issue:12 Topics: Angina Pectoris; Anti-Bacterial Agents; Anticoagulants; Antihypertensive Agents; Arrhythmias, Cardiac; Diet Therapy; Digitalis Glycosides; Heart Diseases; Heart Failure; Humans; Hydrazines; Hypertension; Long-Term Care; Methyldopa; Phytotherapy; Plants, Medicinal; Rauwolfia; Rheumatic Fever; Sympatholytics; Sympathomimetics	1967
The mode of action of -methyldopa. British journal of pharmacology, 1972, Volume: 45, Issue:1 Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Disulfiram; Hydrazines; Hypertension; Methyldopa; Rats; Thiocarbamates	1972
Dependence of arterial pressure on intravascular volume in treated hypertensive patients. The New England journal of medicine, 1972, Apr-20, Volume: 286, Issue:16 Topics: Adult; Aged; Arteries; Blood Pressure; Female; Furosemide; Guanethidine; Humans; Hydrazines; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Plasma Volume; Propranolol; Spironolactone; Triamterene	1972
Antihypertensive and noradrenaline-depleting effects of alpha-methyl-5-hydroxytryptophan in the rat. European journal of pharmacology, 1969, Volume: 7, Issue:1 Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Brain Stem; Female; Hydrazines; Hypertension; Methyltyrosines; Myocardium; Norepinephrine; Rats; Serotonin; Spleen	1969
Depressor responses of the spontaneously hypertensive rats to the anti-hypertensive agents. Japanese journal of pharmacology, 1969, Volume: 19, Issue:3 Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Depression, Chemical; Guanethidine; Heart Rate; Hexamethonium Compounds; Hydrazines; Hypertension; Injections, Subcutaneous; Methyldopa; Protoveratrines; Rats; Reserpine	1969
[Anti-hypertensive therapy in geriatrics]. Minerva medica, 1970, Apr-11, Volume: 61, Issue:29 Topics: Age Factors; Aged; Antihypertensive Agents; Carbamates; Drug Synergism; Female; Humans; Hydrazines; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium Chloride	1970
Modification of the cardiovascular effects of L-dopa by decarboxylase inhibitors. The Journal of clinical investigation, 1971, Volume: 50, Issue:6 Topics: Animals; Aorta; Aromatic Amino Acid Decarboxylase Inhibitors; Arrhythmias, Cardiac; Blood Pressure; Brain; Catecholamines; Dihydroxyphenylalanine; Dogs; Drug Antagonism; Electric Stimulation; Hindlimb; Hydrazines; Hypertension; Kidney; Myocardium; Perfusion; Stereoisomerism; Vascular Resistance	1971
[Medical therapy of arterial hypertension]. Cardiologia pratica, 1968, Volume: 19, Issue:5 Topics: Antihypertensive Agents; Arteries; Diuretics; Guanethidine; Humans; Hydrazines; Hypertension; Mecamylamine; Methyldopa; Phytotherapy; Plants, Medicinal; Rauwolfia; Reserpine	1968
Interaction between some cheeses and monoamine oxydase inhibitors. Arzneimittel-Forschung, 1968, Volume: 18, Issue:9 Topics: Animals; Blood Pressure; Cats; Cheese; Depression, Chemical; Female; Hydrazines; Hypertension; Male; Monoamine Oxidase Inhibitors; Nialamide; Nictitating Membrane; Pargyline; Phentolamine; Reserpine; Stimulation, Chemical; Tyramine	1968
[On the antihypertensive activity of some drugs alone or in various associations]. Minerva cardioangiologica, 1966, Volume: 14, Issue:10 Topics: Adult; Aged; Antihypertensive Agents; Arteriosclerosis; Carbamates; Female; Humans; Hydrazines; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Male; Middle Aged; Potassium Chloride	1966