nimesulide has been researched along with Hypertension in 4 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cyclooxygenase (COX)-derived prostanoids contribute to angiotensin II (ANG II) hypertension (HTN)." | 7.79 | Cyclooxygenase-1 inhibition attenuates angiotensin II-salt hypertension and neurogenic pressor activity in the rat. ( Asirvatham-Jeyaraj, N; Fink, GD; King, AJ; Madan, S; Northcott, CA, 2013) |
| " This article describes the case of a patient affected by pheochromocytoma in whom multiple organ failure developed after contemporary administration of ergotamine, caffeine, and nimesulide." | 7.69 | Pheochromocytoma crisis caused by contemporary ergotamine, caffeine, and nimesulide administration. ( Bartoli, P; Bonechi, F; Brandinelli, A; Del Rosso, A; Fradella, G; Ieri, A; Maioli, M; Mannelli, M; Mazza, F; Russo, L; Sansoni, M; Zipoli, A, 1997) |
| "Rofecoxib also reduced cardiac hypertrophy." | 5.33 | Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats. ( de Champlain, J; Laplante, MA; Wu, R, 2005) |
| "Cyclooxygenase (COX)-derived prostanoids contribute to angiotensin II (ANG II) hypertension (HTN)." | 3.79 | Cyclooxygenase-1 inhibition attenuates angiotensin II-salt hypertension and neurogenic pressor activity in the rat. ( Asirvatham-Jeyaraj, N; Fink, GD; King, AJ; Madan, S; Northcott, CA, 2013) |
| " Deletion of the PGI2 receptor (IP) or suppression of PGI2 with the selective COX-2 inhibitor, nimesulide, both augment intimal hyperplasia while preserving luminal geometry in mouse models of transplant arteriosclerosis or flow-induced vascular remodeling." | 3.73 | COX-2-derived prostacyclin modulates vascular remodeling. ( Austin, S; Brinster, D; Cheng, Y; Coffman, TM; FitzGerald, GA; Fries, S; Rudic, RD; Song, WL, 2005) |
| " This article describes the case of a patient affected by pheochromocytoma in whom multiple organ failure developed after contemporary administration of ergotamine, caffeine, and nimesulide." | 3.69 | Pheochromocytoma crisis caused by contemporary ergotamine, caffeine, and nimesulide administration. ( Bartoli, P; Bonechi, F; Brandinelli, A; Del Rosso, A; Fradella, G; Ieri, A; Maioli, M; Mannelli, M; Mazza, F; Russo, L; Sansoni, M; Zipoli, A, 1997) |
| "Rofecoxib also reduced cardiac hypertrophy." | 1.33 | Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats. ( de Champlain, J; Laplante, MA; Wu, R, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asirvatham-Jeyaraj, N | 1 |
| King, AJ | 1 |
| Northcott, CA | 1 |
| Madan, S | 1 |
| Fink, GD | 1 |
| Wu, R | 1 |
| Laplante, MA | 1 |
| de Champlain, J | 1 |
| Rudic, RD | 1 |
| Brinster, D | 1 |
| Cheng, Y | 1 |
| Fries, S | 1 |
| Song, WL | 1 |
| Austin, S | 1 |
| Coffman, TM | 1 |
| FitzGerald, GA | 1 |
| Del Rosso, A | 1 |
| Fradella, G | 1 |
| Russo, L | 1 |
| Bartoli, P | 1 |
| Bonechi, F | 1 |
| Brandinelli, A | 1 |
| Maioli, M | 1 |
| Mazza, F | 1 |
| Sansoni, M | 1 |
| Zipoli, A | 1 |
| Mannelli, M | 1 |
| Ieri, A | 1 |
4 other studies available for nimesulide and Hypertension
| Article | Year |
|---|---|
Cyclooxygenase-1 inhibition attenuates angiotensin II-salt hypertension and neurogenic pressor activity in the rat.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cyclooxygenase 1; Cyclooxygenase 2 | 2013 |
Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiomegaly; Cells, Cult | 2005 |
COX-2-derived prostacyclin modulates vascular remodeling.
Topics: Animals; Arteries; Arteriosclerosis; Blood Vessels; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; C | 2005 |
Pheochromocytoma crisis caused by contemporary ergotamine, caffeine, and nimesulide administration.
Topics: Adrenal Gland Neoplasms; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; A | 1997 |