8-((4-chlorophenyl)thio)cyclic-3',5'-amp profile

8-((4-chlorophenyl)thio)cyclic-3',5'-AMP: lowers cAMP in heart & fat cells; cAMP-dependent kinase inhibitor [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

8-(4-chlorophenylthio)-cAMP : A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic AMP in which the hydrogen at position 2 on the purine fragment is replaced by a 4-chlorophenylthio group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

ID Source	ID
PubMed CID	91636
CHEMBL ID	230552
CHEBI ID	84612
SCHEMBL ID	7521869
MeSH ID	M0065582

Synonym
4h-furo[3,2-d]-1,3,2-dioxaphosphorin-7-ol, 6-[6-amino-8-[(4-chlorophenyl)thio]-9h-purin-9-yl]tetrahydro-2-hydroxy-, 2-oxide, (4ar,6r,7r,7as)-
8-p-chlorophenylthio-camp
(4ar,6r,7r,7as)-6-[6-amino-8-(4-chlorophenyl)sulfanyl-purin-9-yl]-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4h-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
8-((4-chlorophenyl)thio)cyclic-3',5'-amp
adenosine, 8-((4-chlorophenyl)thio)-, cyclic 3',5'-(hydrogen phosphate)
8-parachlorophenylthio camp
8-(4-chlorophenylthio)-camp
8-ctp-camp
8-(4-chlorothiophenyl)cyclic amp
rp-cpt-camps
8-cpt-camp
8-(p-chlorophenylthio)cyclic-3',5'-amp
8-(4-chlorophenylthio)-cyclic amp
(4ar,6r,7r,7as)-6-{6-amino-8-[(4-chlorophenyl)sulfanyl]-9h-purin-9-yl}tetrahydro-4h-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide
41941-66-6
chlorophenylthio-camp
chebi:84612 ,
8-pcpt-camp
CHEMBL230552 ,
SCHEMBL7521869
8-(4-chlorophenylthio)-3',5'-cyclic amp
8-(4-chlorophenylthio)adenosine cyclic 3',5'-phosphate
(4ar,6r,7r,7as)-6-{6-amino-8-[(4-chlorophenyl)sulfanyl]-9h-purin-9-yl}-2,7-dihydroxytetrahydro-2h,4h-2lambda(5)-furo[3,2-d][1,3,2]dioxaphosphinin-2-one
DTXSID6040402
Q27157915
bdbm50215106
GLXC-27001
PD052881

Role	Description
protein kinase agonist	An agonist that selectively binds to and activates a protein kinase receptor.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
3',5'-cyclic purine nucleotide
adenyl ribonucleotide	A purine riboncleotide where adenine is the purine.
organochlorine compound	An organochlorine compound is a compound containing at least one carbon-chlorine bond.
aryl sulfide	Any organic sulfide in which the sulfur is attached to at least one aromatic group.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)	IC50 (µMol)	81.3333	0.0000	1.0680	10.0000	AID219834; AID219983
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)	IC50 (µMol)	81.3333	0.0000	1.1040	10.0000	AID219834; AID219983
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)	IC50 (µMol)	81.3333	0.0000	1.4651	10.0000	AID219834; AID219983
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)	IC50 (µMol)	81.3333	0.0000	1.1463	10.0000	AID219834; AID219983
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Process	via Protein(s)	Taxonomy
cAMP catabolic process	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
signal transduction	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
G protein-coupled receptor signaling pathway	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
sensory perception of smell	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
regulation of protein kinase A signaling	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
cellular response to xenobiotic stimulus	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
cAMP-mediated signaling	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
neutrophil homeostasis	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
cAMP catabolic process	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
neutrophil chemotaxis	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
positive regulation of type II interferon production	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
positive regulation of interleukin-2 production	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
T cell receptor signaling pathway	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
leukocyte migration	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
cellular response to lipopolysaccharide	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
cellular response to xenobiotic stimulus	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
cellular response to epinephrine stimulus	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
regulation of cardiac muscle cell contraction	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
negative regulation of relaxation of cardiac muscle	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
cAMP-mediated signaling	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
cAMP catabolic process	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)
cAMP-mediated signaling	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)
regulation of heart rate	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
cAMP catabolic process	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
positive regulation of heart rate	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
positive regulation of type II interferon production	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
positive regulation of interleukin-2 production	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
positive regulation of interleukin-5 production	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
negative regulation of peptidyl-serine phosphorylation	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
negative regulation of heart contraction	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
T cell receptor signaling pathway	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
establishment of endothelial barrier	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
adrenergic receptor signaling pathway	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
regulation of cardiac muscle cell contraction	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
regulation of cell communication by electrical coupling involved in cardiac conduction	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
negative regulation of relaxation of cardiac muscle	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
cAMP-mediated signaling	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
3',5'-cyclic-AMP phosphodiesterase activity	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
protein binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
cAMP binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
metal ion binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
3',5'-cyclic-GMP phosphodiesterase activity	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
3',5'-cyclic-AMP phosphodiesterase activity	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
calcium channel regulator activity	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
protein binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
cAMP binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
gamma-tubulin binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
transmembrane transporter binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
metal ion binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
3',5'-cyclic-GMP phosphodiesterase activity	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
3',5'-cyclic-AMP phosphodiesterase activity	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)
metal ion binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)
3',5'-cyclic-GMP phosphodiesterase activity	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)
3',5'-cyclic-nucleotide phosphodiesterase activity	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
3',5'-cyclic-AMP phosphodiesterase activity	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
calcium channel regulator activity	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
protein binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
enzyme binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
signaling receptor regulator activity	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
cAMP binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
beta-2 adrenergic receptor binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
transmembrane transporter binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
metal ion binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
ATPase binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
scaffold protein binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
heterocyclic compound binding	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
3',5'-cyclic-GMP phosphodiesterase activity	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
nucleoplasm	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
cytosol	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
plasma membrane	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
membrane	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
ruffle membrane	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
perinuclear region of cytoplasm	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
perinuclear region of cytoplasm	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
cytosol	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
nucleus	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)
centrosome	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
cytosol	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
synaptic vesicle	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
postsynaptic density	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
Z disc	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
dendritic spine	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
excitatory synapse	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
gamma-tubulin complex	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
voltage-gated calcium channel complex	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
nucleus	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
perinuclear region of cytoplasm	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
cytosol	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)
extracellular space	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)
cytosol	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)
cilium	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)
cytosol	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)
nucleus	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)
perinuclear region of cytoplasm	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)
centrosome	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
cytosol	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
plasma membrane	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
apical plasma membrane	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
voltage-gated calcium channel complex	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
calcium channel complex	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
cytosol	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
nucleus	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
perinuclear region of cytoplasm	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Assay ID	Title	Year	Journal	Article
AID1145761	Ratio of Ka for cAMP to Ka for compound for bovine brain protein kinase in presence of 0.5 nmol [32P]ATP-gamma by liquid scintillation spectrometer	1976	Journal of medicinal chemistry, Mar, Volume: 19, Issue:3	Synthesis of some 1, 8- and 2, 8-disubstituted derivatives of adenosine cyclic 3', 5'-phosphate and their interaction with some enzymes of cAMP metabolism.
AID219827	Activate a partially purified type II cAMP-dependent protein kinase from bovine brain	1980	Journal of medicinal chemistry, Mar, Volume: 23, Issue:3	Synthesis and enzymatic and inotropic activity of some new 8-substituted and 6,8-disubstituted derivatives of adenosine cyclic 3',5'-monophosphate.
AID219982	Susceptibility to be hydrolysed by a partially purified cAMP phosphodiesterase from rabbit kidney	1980	Journal of medicinal chemistry, Mar, Volume: 23, Issue:3	Synthesis and enzymatic and inotropic activity of some new 8-substituted and 6,8-disubstituted derivatives of adenosine cyclic 3',5'-monophosphate.
AID1145762	Activity of rabbit kidney PDE assessed as enzyme-mediated compound hydrolysis after 10 to 60 mins by colorimetric assay relative to cAMP	1976	Journal of medicinal chemistry, Mar, Volume: 19, Issue:3	Synthesis of some 1, 8- and 2, 8-disubstituted derivatives of adenosine cyclic 3', 5'-phosphate and their interaction with some enzymes of cAMP metabolism.
AID219834	Inhibition of cAMP phosphodiesterase preparation from bovine heart at a substrate concentration of 0.14 uM	1980	Journal of medicinal chemistry, Mar, Volume: 23, Issue:3	Synthesis and enzymatic and inotropic activity of some new 8-substituted and 6,8-disubstituted derivatives of adenosine cyclic 3',5'-monophosphate.
AID297178	Activation of olfactory CNG A2A41b channel expressed in HEK293 cells assessed as effect on half maximal current	2007	Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17	Novel N7- and N1-substituted cGMP derivatives are potent activators of cyclic nucleotide-gated channels.
AID1145763	Inhibition of rabbit lung PDE assessed as inhibition 8-[3H]-cAMP substrate hydrolysis	1976	Journal of medicinal chemistry, Mar, Volume: 19, Issue:3	Synthesis of some 1, 8- and 2, 8-disubstituted derivatives of adenosine cyclic 3', 5'-phosphate and their interaction with some enzymes of cAMP metabolism.
AID219983	Inhibition of cAMP phosphodiesterase preparation from rabbit lung at a substrate concentration of 0.14 uM	1980	Journal of medicinal chemistry, Mar, Volume: 23, Issue:3	Synthesis and enzymatic and inotropic activity of some new 8-substituted and 6,8-disubstituted derivatives of adenosine cyclic 3',5'-monophosphate.
AID1145764	Inhibition of bovine heart PDE assessed as inhibition 8-[3H]-cAMP substrate hydrolysis	1976	Journal of medicinal chemistry, Mar, Volume: 19, Issue:3	Synthesis of some 1, 8- and 2, 8-disubstituted derivatives of adenosine cyclic 3', 5'-phosphate and their interaction with some enzymes of cAMP metabolism.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	82 (14.64)	18.7374
1990's	302 (53.93)	18.2507
2000's	135 (24.11)	29.6817
2010's	40 (7.14)	24.3611
2020's	1 (0.18)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	3 (0.53%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	562 (99.47%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Description	Relationhip Strength	Studies	Classes	Roles
8-bromo cyclic adenosine monophosphate	[no description available]	high	47	3',5'-cyclic purine nucleotide; adenyl ribonucleotide; organobromine compound	antidepressant; protein kinase agonist
8-thio-benzyl cyclic amp	[no description available]	medium	3
8-azidoadenosine-3',5'-monophosphate	[no description available]	medium	1
8-chloro-cyclic adenosine monophosphate	[no description available]	medium	9
n(6)-benzyl-cyclic adenosine 5'-monophosphate	[no description available]	medium	2
8-(methylthio)cyclic 3',5'-adenosine monophosphate	[no description available]	medium	1
8-benzylthio-n(6)-n-butyladenosine cyclic-3,5'-monophosphate	[no description available]	medium	1
cyclic gmp	[no description available]	medium	21	3',5'-cyclic purine nucleotide; guanyl ribonucleotide	Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
8-((4-chlorophenyl)thio)cyclic-3',5'-gmp	[no description available]	high	7	3',5'-cyclic purine nucleotide; aryl sulfide; organochlorine compound; ribonucleotide	protein kinase agonist
colforsin	[no description available]	medium	122	acetate ester; cyclic ketone; labdane diterpenoid; organic heterotricyclic compound; tertiary alpha-hydroxy ketone; triol	adenylate cyclase agonist; anti-HIV agent; antihypertensive agent; plant metabolite; platelet aggregation inhibitor; protein kinase A agonist
dactinomycin	[no description available]	medium	10	actinomycin	mutagen
guanosine triphosphate	[no description available]	medium	4	guanosine 5'-phosphate; purine ribonucleoside 5'-triphosphate	Escherichia coli metabolite; mouse metabolite; uncoupling protein inhibitor
dinoprostone	[no description available]	medium	20	prostaglandins E	human metabolite; mouse metabolite; oxytocic
inositol 1,4,5-trisphosphate	[no description available]	medium	8	myo-inositol trisphosphate	mouse metabolite
calcimycin	[no description available]	medium	7	benzoxazole
6-fluoro-5,7-dibromo-2-methyl-1-formyl-1,2,3,4-tetrahydroquinoline	[no description available]	medium	1
alprostadil	[no description available]	medium	3	prostaglandins E	anticoagulant; human metabolite; platelet aggregation inhibitor; vasodilator agent
glutamic acid	[no description available]	medium	5	glutamic acid; glutamine family amino acid; L-alpha-amino acid; proteinogenic amino acid	Escherichia coli metabolite; ferroptosis inducer; micronutrient; mouse metabolite; neurotransmitter; nutraceutical
butaprost	[no description available]	medium	2
wortmannin	[no description available]	medium	6	acetate ester; cyclic ketone; delta-lactone; organic heteropentacyclic compound	anticoronaviral agent; antineoplastic agent; autophagy inhibitor; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; geroprotector; Penicillium metabolite; radiosensitizing agent
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one	[no description available]	medium	7	chromones; morpholines; organochlorine compound	autophagy inhibitor; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; geroprotector
h 89	[no description available]	medium	15	N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide
myelin basic protein	[no description available]	medium	1
cocaine	[no description available]	medium	1	benzoate ester; methyl ester; tertiary amino compound; tropane alkaloid	adrenergic uptake inhibitor; central nervous system stimulant; dopamine uptake inhibitor; environmental contaminant; local anaesthetic; mouse metabolite; plant metabolite; serotonin uptake inhibitor; sodium channel blocker; sympathomimetic agent; vasoconstrictor agent; xenobiotic
amiloride	[no description available]	medium	16	aromatic amine; guanidines; organochlorine compound; pyrazines	diuretic; sodium channel blocker
cytochalasin d	[no description available]	medium	2
tetradecanoylphorbol acetate	[no description available]	medium	39	acetate ester; diester; phorbol ester; tertiary alpha-hydroxy ketone; tetradecanoate ester	antineoplastic agent; apoptosis inducer; carcinogenic agent; mitogen; plant metabolite; protein kinase C agonist; reactive oxygen species generator
concanamycin a	[no description available]	medium	1	carbamate ester; concanamycin	antifungal agent; EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor; metabolite
deamino arginine vasopressin	[no description available]	medium	1	heterodetic cyclic peptide	diagnostic agent; renal agent; vasopressin receptor agonist
cyclopentane	[no description available]	medium	1	cycloalkane; cyclopentanes; volatile organic compound	non-polar solvent
isoxazoles	[no description available]	medium	1	isoxazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3h-cyclopenta(c)quinolin-8-yl)ethanone	[no description available]	medium	1	agonist
tyramine	[no description available]	medium	1	monoamine molecular messenger; primary amino compound; tyramines	EC 3.1.1.8 (cholinesterase) inhibitor; Escherichia coli metabolite; human metabolite; mouse metabolite; neurotransmitter
propranolol	[no description available]	medium	8	naphthalenes; propanolamine; secondary amine	anti-arrhythmia drug; antihypertensive agent; anxiolytic drug; beta-adrenergic antagonist; environmental contaminant; human blood serum metabolite; vasodilator agent; xenobiotic
milrinone	[no description available]	medium	3	bipyridines; nitrile; pyridone	cardiotonic drug; EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor; platelet aggregation inhibitor; vasodilator agent
phenylephrine	[no description available]	medium	4	phenols; phenylethanolamines; secondary amino compound	alpha-adrenergic agonist; cardiotonic drug; mydriatic agent; nasal decongestant; protective agent; sympathomimetic agent; vasoconstrictor agent
isoproterenol	[no description available]	medium	47	catechols; secondary alcohol; secondary amino compound	beta-adrenergic agonist; bronchodilator agent; cardiotonic drug; sympathomimetic agent
isoleucine	[no description available]	medium	1	aspartate family amino acid; isoleucine; L-alpha-amino acid zwitterion; L-alpha-amino acid; proteinogenic amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
fluorides	[no description available]	medium	3	halide anion; monoatomic fluorine
serine	[no description available]	medium	4	L-alpha-amino acid; proteinogenic amino acid; serine family amino acid; serine zwitterion; serine	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
piperidines	[no description available]	medium	1
guanosine 5'-o-(2-thiodiphosphate)	[no description available]	medium	2	nucleoside diphosphate analogue
am 251	[no description available]	medium	1	amidopiperidine; carbohydrazide; dichlorobenzene; organoiodine compound; pyrazoles	antidepressant; antineoplastic agent; apoptosis inducer; CB1 receptor antagonist
guanosine diphosphate	[no description available]	medium	2	guanosine 5'-phosphate; purine ribonucleoside 5'-diphosphate	Escherichia coli metabolite; mouse metabolite; uncoupling protein inhibitor
lithium	[no description available]	medium	1	alkali metal atom
hydrogen carbonate	[no description available]	medium	7	carbon oxoanion	cofactor; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
n(6)-benzoyl-cyclic amp	[no description available]	medium	3
glycerophosphoinositol 4,5-bisphosphate	[no description available]	medium	3
bradykinin	[no description available]	medium	5	oligopeptide	human blood serum metabolite; vasodilator agent
kallidin	[no description available]	medium	1	peptide
aldosterone	[no description available]	medium	5	11beta-hydroxy steroid; 18-oxo steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; C21-steroid hormone; mineralocorticoid; primary alpha-hydroxy ketone; steroid aldehyde	human metabolite; mouse metabolite
thapsigargin	[no description available]	medium	8	butyrate ester; organic heterotricyclic compound; sesquiterpene lactone	calcium channel blocker; EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor
caffeine	[no description available]	medium	2	purine alkaloid; trimethylxanthine	adenosine A2A receptor antagonist; adenosine receptor antagonist; adjuvant; central nervous system stimulant; diuretic; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; environmental contaminant; food additive; fungal metabolite; geroprotector; human blood serum metabolite; mouse metabolite; mutagen; plant metabolite; psychotropic drug; ryanodine receptor agonist; xenobiotic
u 73122	[no description available]	medium	2	aromatic ether; aza-steroid; maleimides	EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor
kallidin, des-arg(10)-	[no description available]	medium	1
fluoxetine	[no description available]	medium	1	(trifluoromethyl)benzenes; aromatic ether; secondary amino compound
chlorpromazine	[no description available]	medium	2	organochlorine compound; phenothiazines; tertiary amine	anticoronaviral agent; antiemetic; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; phenothiazine antipsychotic drug
arachidonic acid	[no description available]	medium	4	icosa-5,8,11,14-tetraenoic acid; long-chain fatty acid; omega-6 fatty acid	Daphnia galeata metabolite; EC 3.1.1.1 (carboxylesterase) inhibitor; human metabolite; mouse metabolite
dichlororibofuranosylbenzimidazole	[no description available]	medium	7
5,6-dichloro-1-beta-d-ribofuranosylbenzimidazole-3',5'-monophosphorothioate	[no description available]	medium	6
adenine	[no description available]	medium	3	6-aminopurines; purine nucleobase	Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
adenosine-3',5'-cyclic phosphorothioate	[no description available]	medium	11	nucleoside 3',5'-cyclic phosphorothioate
fluorescein-5-isothiocyanate	[no description available]	medium	3	fluorescein isothiocyanate
phosphoserine	[no description available]	medium	4	non-proteinogenic alpha-amino acid; O-phosphoamino acid; serine derivative	human metabolite
adenosine	[no description available]	medium	9	adenosines; purines D-ribonucleoside	analgesic; anti-arrhythmia drug; fundamental metabolite; human metabolite; vasodilator agent
ryanodine	[no description available]	medium	3
uridine triphosphate	[no description available]	medium	2	pyrimidine ribonucleoside 5'-triphosphate; uridine 5'-phosphate	Escherichia coli metabolite; mouse metabolite
inositol 1,4,6-trisphosphate	[no description available]	medium	1	myo-inositol trisphosphate
cinanserin	[no description available]	medium	1	aryl sulfide; cinnamamides; secondary carboxamide; tertiary amino compound	anticoronaviral agent; antiviral agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
tretinoin	[no description available]	medium	5	retinoic acid; vitamin A	anti-inflammatory agent; antineoplastic agent; antioxidant; AP-1 antagonist; human metabolite; keratolytic drug; retinoic acid receptor agonist; retinoid X receptor agonist; signalling molecule
epidermal growth factor	[no description available]	medium	11
endothelin-1	[no description available]	medium	1
isoamyl acetate	[no description available]	medium	1	acetate ester	metabolite; Saccharomyces cerevisiae metabolite
1-methyl-3-isobutylxanthine	[no description available]	medium	61	3-isobutyl-1-methylxanthine
n-pentanol	[no description available]	medium	1	pentanol; short-chain primary fatty alcohol	human metabolite; plant metabolite
arsenic	[no description available]	medium	4	metalloid atom; pnictogen	micronutrient
arsenic trioxide	[no description available]	medium	3
kt 5823	[no description available]	medium	2	gamma-lactam; hemiaminal; indolocarbazole; methyl ester; organic heterooctacyclic compound	EC 2.7.11.12 (cGMP-dependent protein kinase) inhibitor
chelerythrine	[no description available]	medium	1	benzophenanthridine alkaloid; organic cation	antibacterial agent; antineoplastic agent; EC 2.7.11.13 (protein kinase C) inhibitor
iodine	[no description available]	medium	6	halide anion; monoatomic iodine	human metabolite
carbocyanines	[no description available]	medium	1	cyanine dye; organic iodide salt	fluorochrome
potassium chloride	[no description available]	medium	3	inorganic chloride; inorganic potassium salt; potassium salt	fertilizer
capsaicin	[no description available]	medium	2	capsaicinoid	non-narcotic analgesic; TRPV1 agonist; voltage-gated sodium channel blocker
4-aminopyridine	[no description available]	medium	8	aminopyridine; aromatic amine	avicide; orphan drug; potassium channel blocker
4,4'-diisothiocyanostilbene-2,2'-disulfonic acid	[no description available]	medium	12
chlorine	[no description available]	medium	37	halide anion; monoatomic chlorine	cofactor; Escherichia coli metabolite; human metabolite
biotin	[no description available]	medium	1	biotins; vitamin B7	coenzyme; cofactor; Escherichia coli metabolite; fundamental metabolite; human metabolite; mouse metabolite; nutraceutical; prosthetic group; Saccharomyces cerevisiae metabolite
1-(carboxymethylthio)tetradecane	[no description available]	medium	1	straight-chain fatty acid
cytochrome c-t	[no description available]	medium	1
urotensin i	[no description available]	medium	1
pyrroles	[no description available]	medium	9	pyrrole; secondary amine
sauvagine	[no description available]	medium	1
cp 154526	[no description available]	medium	1
bay-k-8644	[no description available]	medium	2	(trifluoromethyl)benzenes; C-nitro compound; dihydropyridine; methyl ester
bucladesine	[no description available]	medium	46	3',5'-cyclic purine nucleotide
kn 93	[no description available]	medium	2	monochlorobenzenes; monomethoxybenzene; primary alcohol; sulfonamide; tertiary amino compound	EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor; geroprotector
kn 92	[no description available]	medium	1
pituitrin	[no description available]	medium	13
cesium	[no description available]	medium	2	alkali metal atom
zd 7288	[no description available]	medium	1
oxophenylarsine	[no description available]	medium	1	arsine oxides	antineoplastic agent; apoptosis inducer; EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
dithiothreitol	[no description available]	medium	1	1,4-dimercaptobutane-2,3-diol; butanediols; dithiol; glycol; thiol	chelator; human metabolite; reducing agent
quinpirole	[no description available]	medium	2	pyrazoloquinoline	dopamine agonist
chromium	[no description available]	medium	1	chromium cation; monoatomic hexacation
cyclosporine	[no description available]	medium	1
tranylcypromine	[no description available]	medium	1	2-phenylcyclopropan-1-amine
chromium	[no description available]	medium	1	chromium group element atom; metal allergen	micronutrient
desipramine	[no description available]	medium	1	dibenzoazepine; secondary amino compound	adrenergic uptake inhibitor; alpha-adrenergic antagonist; antidepressant; cholinergic antagonist; drug allergen; EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; H1-receptor antagonist; serotonin uptake inhibitor
lactacystin	[no description available]	medium	1	lactam; S-substituted L-cysteine
acetylcysteine	[no description available]	medium	1	acetylcysteine; L-cysteine derivative; N-acetyl-L-amino acid	antidote to paracetamol poisoning; antiinfective agent; antioxidant; antiviral drug; ferroptosis inhibitor; geroprotector; human metabolite; mucolytic; radical scavenger; vulnerary
leupeptins	[no description available]	medium	2
benzyloxycarbonylleucyl-leucyl-leucine aldehyde	[no description available]	medium	1	amino aldehyde; carbamate ester; tripeptide	proteasome inhibitor
m&b 28,767	[no description available]	medium	1
ng-nitroarginine methyl ester	[no description available]	medium	3	alpha-amino acid ester; L-arginine derivative; methyl ester; N-nitro compound	EC 1.14.13.39 (nitric oxide synthase) inhibitor
ah 23848	[no description available]	medium	1	(4Z)-7-{5-[([1,1'-biphenyl]-4-yl)methoxy]-2-(morpholin-4-yl)-3-oxocyclopentyl}hept-4-enoic acid
16,16-dimethylprostaglandin e2	[no description available]	medium	1	cyclopentanones; monocarboxylic acid; prostanoid; secondary allylic alcohol	anti-ulcer drug; gastrointestinal drug; radiation protective agent
8-bromoadenosine	[no description available]	medium	1	purine nucleoside
glyburide	[no description available]	medium	6	monochlorobenzenes; N-sulfonylurea	anti-arrhythmia drug; EC 2.7.1.33 (pantothenate kinase) inhibitor; EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor; hypoglycemic agent
indomethacin	[no description available]	medium	8	aromatic ether; indole-3-acetic acids; monochlorobenzenes; N-acylindole	analgesic; drug metabolite; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; environmental contaminant; gout suppressant; non-steroidal anti-inflammatory drug; xenobiotic metabolite; xenobiotic
sodium fluoride	[no description available]	medium	3	fluoride salt	mutagen
pd 98059	[no description available]	medium	6	aromatic amine; monomethoxyflavone	EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; geroprotector
ag-490	[no description available]	medium	1	catechols; enamide; monocarboxylic acid amide; nitrile; secondary carboxamide	anti-inflammatory agent; antioxidant; apoptosis inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; geroprotector; STAT3 inhibitor
kt 5720	[no description available]	medium	7	carboxylic ester; gamma-lactam; hemiaminal; indolocarbazole; organic heterooctacyclic compound; semisynthetic derivative; tertiary alcohol	EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor
linsidomine	[no description available]	medium	1	morpholines
molsidomine	[no description available]	medium	1	ethyl ester; morpholines; oxadiazole; zwitterion	antioxidant; apoptosis inhibitor; cardioprotective agent; nitric oxide donor; vasodilator agent
s-nitrosoglutathione	[no description available]	medium	1	glutathione derivative; nitrosothio compound	bronchodilator agent; nitric oxide donor; platelet aggregation inhibitor; signalling molecule
ouabain	[no description available]	medium	7	11alpha-hydroxy steroid; 14beta-hydroxy steroid; 5beta-hydroxy steroid; alpha-L-rhamnoside; cardenolide glycoside; steroid hormone	anti-arrhythmia drug; cardiotonic drug; EC 2.3.3.1 [citrate (Si)-synthase] inhibitor; EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor; EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor; EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor; ion transport inhibitor; plant metabolite
iberiotoxin	[no description available]	medium	1
8-bromocyclic gmp	[no description available]	medium	7	3',5'-cyclic purine nucleotide; organobromine compound	muscle relaxant; protein kinase G agonist
oxadiazoles	[no description available]	medium	1
quinoxalines	[no description available]	medium	2	mancude organic heterobicyclic parent; naphthyridine; ortho-fused heteroarene
triazoles	[no description available]	medium	1	1,2,3-triazole
1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one	[no description available]	medium	1	oxadiazoloquinoxaline	EC 4.6.1.2 (guanylate cyclase) inhibitor
lysophosphatidic acid	[no description available]	medium	2	1-acyl-sn-glycerol 3-phosphate
atrial natriuretic factor	[no description available]	medium	4	polypeptide
h 85	[no description available]	medium	1
calpain inhibitor iii	[no description available]	medium	1
calpain	[no description available]	medium	1
glycidyl nitrate	[no description available]	medium	1
interleukin-8	[no description available]	medium	1
salmeterol xinafoate	[no description available]	medium	1	naphthoic acid
albuterol	[no description available]	medium	1	phenols; phenylethanolamines; secondary amino compound	beta-adrenergic agonist; bronchodilator agent; environmental contaminant; xenobiotic
oxidopamine	[no description available]	medium	1	benzenetriol; catecholamine; primary amino compound	drug metabolite; human metabolite; neurotoxin
okadaic acid	[no description available]	medium	9	ketal
arginine vasopressin	[no description available]	medium	20	vasopressin	cardiovascular drug; hematologic agent; mitogen
dorsomorphin	[no description available]	medium	1	aromatic ether; piperidines; pyrazolopyrimidine; pyridines	bone morphogenetic protein receptor antagonist; EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} inhibitor
ziconotide	[no description available]	medium	1
strontium	[no description available]	medium	1	alkaline earth metal atom
amifampridine	[no description available]	medium	1	aminopyridine
phentolamine	[no description available]	medium	3	imidazoles; phenols; substituted aniline; tertiary amino compound	alpha-adrenergic antagonist; vasodilator agent
dobutamine	[no description available]	medium	1	catecholamine; secondary amine	beta-adrenergic agonist; cardiotonic drug; sympathomimetic agent
yohimbine	[no description available]	medium	1	methyl 17-hydroxy-20xi-yohimban-16-carboxylate	alpha-adrenergic antagonist; dopamine receptor D2 antagonist; serotonergic antagonist
cycloheximide	[no description available]	medium	23	antibiotic fungicide; cyclic ketone; dicarboximide; piperidine antibiotic; piperidones; secondary alcohol	anticoronaviral agent; bacterial metabolite; ferroptosis inhibitor; neuroprotective agent; protein synthesis inhibitor
carbachol	[no description available]	medium	12	ammonium salt; carbamate ester	cardiotonic drug; miotic; muscarinic agonist; nicotinic acetylcholine receptor agonist; non-narcotic analgesic
physostigmine	[no description available]	medium	1	carbamate ester; indole alkaloid	antidote to curare poisoning; EC 3.1.1.8 (cholinesterase) inhibitor; miotic
atropine	[no description available]	medium	1
tubocurarine	[no description available]	medium	1	bisbenzylisoquinoline alkaloid	drug allergen; muscle relaxant; nicotinic antagonist
hexamethonium	[no description available]	medium	1	quaternary ammonium salt
1-anilino-8-naphthalenesulfonate	[no description available]	medium	1	aminonaphthalene; naphthalenesulfonic acid	fluorescent probe
monensin	[no description available]	medium	2	cyclic hemiketal; monocarboxylic acid; polyether antibiotic; spiroketal	antifungal agent; coccidiostat; ionophore
4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone	[no description available]	medium	4	methoxybenzenes
clonidine	[no description available]	medium	2	clonidine; imidazoline
timolol	[no description available]	medium	1	timolol	anti-arrhythmia drug; antiglaucoma drug; antihypertensive agent; beta-adrenergic antagonist
urea	[no description available]	medium	3	isourea; monocarboxylic acid amide; one-carbon compound	Daphnia magna metabolite; Escherichia coli metabolite; fertilizer; flour treatment agent; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
sucrose	[no description available]	medium	2	glycosyl glycoside	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; osmolyte; Saccharomyces cerevisiae metabolite; sweetening agent
2-chloroadenosine	[no description available]	medium	2	purine nucleoside
adenosine monophosphate	[no description available]	medium	2	adenosine 5'-phosphate; purine ribonucleoside 5'-monophosphate	adenosine A1 receptor agonist; cofactor; EC 3.1.3.1 (alkaline phosphatase) inhibitor; EC 3.1.3.11 (fructose-bisphosphatase) inhibitor; fundamental metabolite; micronutrient; nutraceutical
thiourea	[no description available]	medium	1	one-carbon compound; thioureas; ureas	antioxidant; chromophore
histamine	[no description available]	medium	3	aralkylamino compound; imidazoles	human metabolite; mouse metabolite; neurotransmitter
dimaprit	[no description available]	medium	1	imidothiocarbamic ester
vasoactive intestinal peptide	[no description available]	medium	6
furosemide	[no description available]	medium	4	chlorobenzoic acid; furans; sulfonamide	environmental contaminant; loop diuretic; xenobiotic
digitonin	[no description available]	medium	2
palmitic acid	[no description available]	medium	1	long-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; Daphnia magna metabolite; EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor; plant metabolite
oleic acid	[no description available]	medium	2	octadec-9-enoic acid	antioxidant; Daphnia galeata metabolite; EC 3.1.1.1 (carboxylesterase) inhibitor; Escherichia coli metabolite; mouse metabolite; plant metabolite; solvent
phosphatidylcholines	[no description available]	medium	4	1,2-diacyl-sn-glycero-3-phosphocholine
glucosamine	[no description available]	medium	1	D-glucosamine	Escherichia coli metabolite; geroprotector; mouse metabolite
deoxyglucose	[no description available]	medium	2
sq-23377	[no description available]	medium	17	cyclic ether; enol; polyunsaturated fatty acid; very long-chain fatty acid	calcium ionophore; metabolite
nystatin a1	[no description available]	medium	1	nystatins
calixarenes	[no description available]	medium	1
theophylline	[no description available]	medium	14	dimethylxanthine	adenosine receptor antagonist; anti-asthmatic drug; anti-inflammatory agent; bronchodilator agent; drug metabolite; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; fungal metabolite; human blood serum metabolite; immunomodulator; muscle relaxant; vasodilator agent
cromakalim	[no description available]	medium	2
tetraethylammonium	[no description available]	medium	10	quaternary ammonium ion
concanavalin a	[no description available]	medium	2
citralva	[no description available]	medium	1
tolbutamide	[no description available]	medium	3	N-sulfonylurea	human metabolite; hypoglycemic agent; insulin secretagogue; potassium channel blocker
leucine	[no description available]	medium	3	amino acid zwitterion; L-alpha-amino acid; leucine; proteinogenic amino acid; pyruvate family amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
tetrodotoxin	[no description available]	medium	4	azatetracycloalkane; oxatetracycloalkane; quinazoline alkaloid	animal metabolite; bacterial metabolite; marine metabolite; neurotoxin; voltage-gated sodium channel blocker
bumetanide	[no description available]	medium	5	amino acid; benzoic acids; sulfonamide	diuretic; EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor
charybdotoxin	[no description available]	medium	4
1,2-bis(2-aminophenoxy)ethane-n,n,n',n'-tetraacetic acid	[no description available]	medium	4	polyamino carboxylic acid; tetracarboxylic acid	chelator
egtazic acid	[no description available]	medium	8	diether; tertiary amino compound; tetracarboxylic acid	chelator
barium	[no description available]	medium	6	alkaline earth metal atom; elemental barium
fura-2	[no description available]	medium	6
quinidine	[no description available]	medium	2	cinchona alkaloid	alpha-adrenergic antagonist; anti-arrhythmia drug; antimalarial; drug allergen; EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor; EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor; muscarinic antagonist; P450 inhibitor; potassium channel blocker; sodium channel blocker
amphotericin b	[no description available]	medium	2	antibiotic antifungal drug; macrolide antibiotic; polyene antibiotic	antiamoebic agent; antiprotozoal drug; bacterial metabolite
diphenylamine	[no description available]	medium	1	aromatic amine; bridged diphenyl fungicide; secondary amino compound	antifungal agrochemical; antioxidant; carotogenesis inhibitor; EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor; ferroptosis inhibitor; radical scavenger
3',5-dichlorodiphenylamine-2-carboxylic acid	[no description available]	medium	1
mk 473	[no description available]	medium	1
4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid	[no description available]	medium	3	stilbenoid
adenosine 5'-o-(3-thiotriphosphate)	[no description available]	medium	2	nucleoside triphosphate analogue
adenylyl imidodiphosphate	[no description available]	medium	2	adenosine 5'-phosphate
carbonyl cyanide m-chlorophenyl hydrazone	[no description available]	medium	1	hydrazone; monochlorobenzenes; nitrile	antibacterial agent; geroprotector; ionophore
4-chloromercuribenzenesulfonate	[no description available]	medium	2	arenesulfonic acid; arylmercury compound
8-aminohexylamino camp	[no description available]	medium	1
tyrosine	[no description available]	medium	2	amino acid zwitterion; erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid; proteinogenic amino acid; tyrosine	EC 1.3.1.43 (arogenate dehydrogenase) inhibitor; fundamental metabolite; micronutrient; nutraceutical
glucagon	[no description available]	medium	20	peptide hormone
phosphotyrosine	[no description available]	medium	1	L-tyrosine derivative; non-proteinogenic L-alpha-amino acid; O(4)-phosphotyrosine	Escherichia coli metabolite; immunogen
1-(5-isoquinolinesulfonyl)-2-methylpiperazine	[no description available]	medium	9	isoquinolines; N-sulfonylpiperazine	EC 2.7.11.13 (protein kinase C) inhibitor
nifedipine	[no description available]	medium	2	C-nitro compound; dihydropyridine; methyl ester	calcium channel blocker; human metabolite; tocolytic agent; vasodilator agent
verapamil	[no description available]	medium	1	aromatic ether; nitrile; polyether; tertiary amino compound
phenobarbital	[no description available]	medium	1	barbiturates	anticonvulsant; drug allergen; excitatory amino acid antagonist; sedative
beta-naphthoflavone	[no description available]	medium	1	extended flavonoid; naphtho-gamma-pyrone; organic heterotricyclic compound	aryl hydrocarbon receptor agonist
oxytocin	[no description available]	medium	6	heterodetic cyclic peptide; peptide hormone	oxytocic; vasodilator agent
calcitriol	[no description available]	medium	2	D3 vitamins; hydroxycalciol; triol	antineoplastic agent; antipsoriatic; bone density conservation agent; calcium channel agonist; calcium channel modulator; hormone; human metabolite; immunomodulator; metabolite; mouse metabolite; nutraceutical
transforming growth factor beta	[no description available]	medium	1
aluminum maltolate	[no description available]	medium	1
aluminum	[no description available]	medium	3	boron group element atom; elemental aluminium; metal atom
deferoxamine	[no description available]	medium	2	acyclic desferrioxamine	bacterial metabolite; ferroptosis inhibitor; iron chelator; siderophore
4-chloro-7-nitrobenzofurazan	[no description available]	medium	1	benzoxadiazole; C-nitro compound; organochlorine compound	EC 1.4.3.4 (monoamine oxidase) inhibitor; EC 3.6.1.3 (adenosinetriphosphatase) inhibitor; fluorescent probe; fluorochrome
ammonium chloride	[no description available]	medium	1	ammonium salt; inorganic chloride	ferroptosis inhibitor
n-(7-(4-nitrobenzo-2-oxa-1,3-diazole))-6-aminocaproyl sphingosine	[no description available]	medium	1	N-acylsphingosine	fluorescent probe
cordycepin	[no description available]	medium	1	3'-deoxyribonucleoside; adenosines	antimetabolite; nucleoside antibiotic
benzamil	[no description available]	medium	1	guanidines; pyrazines
nicardipine	[no description available]	medium	1	benzenes; C-nitro compound; diester; dihydropyridine; methyl ester; tertiary amino compound
cyanogen bromide	[no description available]	medium	1
flunitrazepam	[no description available]	medium	1	1,4-benzodiazepinone; C-nitro compound; monofluorobenzenes	anxiolytic drug; GABAA receptor agonist; sedative
phosphorus radioisotopes	[no description available]	medium	3
glycerol	[no description available]	medium	2	alditol; triol	algal metabolite; detergent; Escherichia coli metabolite; geroprotector; human metabolite; mouse metabolite; osmolyte; Saccharomyces cerevisiae metabolite; solvent
trifluoperazine	[no description available]	medium	2	N-alkylpiperazine; N-methylpiperazine; organofluorine compound; phenothiazines	antiemetic; calmodulin antagonist; dopaminergic antagonist; EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor; EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor; phenothiazine antipsychotic drug
chlorethylclonidine	[no description available]	medium	1
manganese	[no description available]	medium	1	elemental manganese; manganese group element atom	Escherichia coli metabolite; micronutrient
beta-glycerophosphoric acid	[no description available]	medium	1	glycerol monophosphate	Escherichia coli metabolite; plant metabolite
n-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide	[no description available]	medium	6	isoquinolines; sulfonamide
neuropeptide y	[no description available]	medium	2
cytochalasin b	[no description available]	medium	1	cytochalasin; lactam; lactone; organic heterotricyclic compound	actin polymerisation inhibitor; metabolite; mycotoxin; platelet aggregation inhibitor
colchicine	[no description available]	medium	1	alkaloid; colchicine	anti-inflammatory agent; gout suppressant; mutagen
brimonidine tartrate	[no description available]	medium	1
phorbol-12,13-didecanoate	[no description available]	medium	1
barium chloride	[no description available]	medium	3	barium salt; inorganic chloride	potassium channel blocker
fura-2-am	[no description available]	medium	2
glycolipids	[no description available]	medium	1
diacetyl	[no description available]	medium	1	alpha-diketone	Escherichia coli metabolite; Saccharomyces cerevisiae metabolite
diacetylmonoxime	[no description available]	medium	1
pindolol	[no description available]	medium	1	indoles; secondary amine	antiglaucoma drug; antihypertensive agent; beta-adrenergic antagonist; serotonergic antagonist; vasodilator agent
ciclopirox	[no description available]	medium	1	cyclic hydroxamic acid; hydroxypyridone antifungal drug; pyridone	antibacterial agent; antiseborrheic
nocodazole	[no description available]	medium	4	aromatic ketone; benzimidazoles; carbamate ester; thiophenes	antimitotic; antineoplastic agent; microtubule-destabilising agent; tubulin modulator
aphidicolin	[no description available]	medium	1	tetracyclic diterpenoid	antimicrobial agent; antimitotic; antineoplastic agent; antiviral drug; apoptosis inducer; Aspergillus metabolite; DNA synthesis inhibitor; EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor; fungal metabolite
arginine	[no description available]	medium	1
mimosine	[no description available]	medium	1	alpha-amino acid
terbutaline	[no description available]	medium	2	phenylethanolamines; resorcinols	anti-asthmatic drug; beta-adrenergic agonist; bronchodilator agent; EC 3.1.1.7 (acetylcholinesterase) inhibitor; hypoglycemic agent; sympathomimetic agent; tocolytic agent
daidzein	[no description available]	medium	1	7-hydroxyisoflavones	antineoplastic agent; EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor; EC 3.2.1.20 (alpha-glucosidase) inhibitor; phytoestrogen; plant metabolite
genistein	[no description available]	medium	5	7-hydroxyisoflavones	antineoplastic agent; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; geroprotector; human urinary metabolite; phytoestrogen; plant metabolite; tyrosine kinase inhibitor
uridine	[no description available]	medium	2	uridines	drug metabolite; fundamental metabolite; human metabolite
ursodeoxycholic acid	[no description available]	medium	1	bile acid; C24-steroid; dihydroxy-5beta-cholanic acid	human metabolite; mouse metabolite
choline	[no description available]	medium	3	cholines	allergen; Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; neurotransmitter; nutrient; plant metabolite; Saccharomyces cerevisiae metabolite
taurocholic acid	[no description available]	medium	2	amino sulfonic acid; bile acid taurine conjugate	human metabolite
saccharin	[no description available]	medium	1	1,2-benzisothiazole; N-sulfonylcarboxamide	environmental contaminant; sweetening agent; xenobiotic
angiotensin ii	[no description available]	medium	4	amino acid zwitterion; angiotensin II	human metabolite
mezerein	[no description available]	medium	1	diterpenoid
staurosporine	[no description available]	medium	6	ammonium ion derivative
dibutyryl cyclic gmp	[no description available]	medium	1
acetazolamide	[no description available]	medium	2	monocarboxylic acid amide; sulfonamide; thiadiazoles	anticonvulsant; diuretic; EC 4.2.1.1 (carbonic anhydrase) inhibitor
2,2,5,7,8-pentamethyl-1-hydroxychroman	[no description available]	medium	1
dinoprost	[no description available]	medium	2	monocarboxylic acid; prostaglandins Falpha	human metabolite; mouse metabolite
dihydrotestosterone	[no description available]	medium	1	17beta-hydroxy steroid; 17beta-hydroxyandrostan-3-one; 3-oxo-5alpha-steroid	androgen; Daphnia magna metabolite; human metabolite; mouse metabolite
cholesteryl oleate	[no description available]	medium	1	CE(18:1); cholesteryl octadec-9-enoate	mouse metabolite
prazosin	[no description available]	medium	2	aromatic ether; furans; monocarboxylic acid amide; piperazines; quinazolines	alpha-adrenergic antagonist; antihypertensive agent; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
benzofurans	[no description available]	medium	3
s-adenosylmethionine	[no description available]	medium	1	organic cation; sulfonium compound	coenzyme; cofactor; human metabolite; micronutrient; Mycoplasma genitalium metabolite; nutraceutical; Saccharomyces cerevisiae metabolite
2-amino-5-phosphonovalerate	[no description available]	medium	1	non-proteinogenic alpha-amino acid	NMDA receptor antagonist
picrotoxin	[no description available]	medium	1
phorbol 12,13-dibutyrate	[no description available]	medium	3	butyrate ester; phorbol ester; tertiary alpha-hydroxy ketone
6-cyano-7-nitroquinoxaline-2,3-dione	[no description available]	medium	1	quinoxaline derivative
gamma-aminobutyric acid	[no description available]	medium	3	amino acid zwitterion; gamma-amino acid; monocarboxylic acid	human metabolite; neurotransmitter; Saccharomyces cerevisiae metabolite; signalling molecule
strychnine	[no description available]	medium	2	monoterpenoid indole alkaloid; organic heteroheptacyclic compound	avicide; cholinergic antagonist; glycine receptor antagonist; neurotransmitter agent; rodenticide
morphine	[no description available]	medium	2	morphinane alkaloid; organic heteropentacyclic compound; tertiary amino compound	anaesthetic; drug allergen; environmental contaminant; geroprotector; mu-opioid receptor agonist; opioid analgesic; plant metabolite; vasodilator agent; xenobiotic
cgp 35348	[no description available]	medium	1
eticlopride	[no description available]	medium	1	salicylamides
calyculin a	[no description available]	medium	2
oxazoles	[no description available]	medium	2	1,3-oxazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
5-nitro-2-(3-phenylpropylamino)benzoic acid	[no description available]	medium	3	nitrobenzoic acid
paclitaxel	[no description available]	medium	1	taxane diterpenoid; tetracyclic diterpenoid	antineoplastic agent; human metabolite; metabolite; microtubule-stabilising agent
1-hexadecyl-2-acetyl-glycero-3-phosphocholine	[no description available]	medium	2	2-acetyl-1-alkyl-sn-glycero-3-phosphocholine	antihypertensive agent; beta-adrenergic antagonist; bronchoconstrictor agent; hematologic agent; vasodilator agent
enkephalin, leucine	[no description available]	medium	5	pentapeptide; peptide zwitterion	analgesic; delta-opioid receptor agonist; human metabolite; mu-opioid receptor agonist; neurotransmitter; rat metabolite
naloxone	[no description available]	medium	4	morphinane alkaloid; organic heteropentacyclic compound; tertiary alcohol	antidote to opioid poisoning; central nervous system depressant; mu-opioid receptor antagonist
zinterol	[no description available]	medium	1
miconazole	[no description available]	medium	1	dichlorobenzene; ether; imidazoles
n(6)-cyclohexyladenosine	[no description available]	medium	1
alanine	[no description available]	medium	1	alanine zwitterion; alanine; L-alpha-amino acid; proteinogenic amino acid; pyruvate family amino acid	EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor; fundamental metabolite
9-(tetrahydro-2-furyl)-adenine	[no description available]	medium	2
methacholine chloride	[no description available]	medium	1	quaternary ammonium salt
1,9-dideoxyforskolin	[no description available]	medium	1	acetate ester; labdane diterpenoid; organic heterotricyclic compound	plant metabolite
fmrfamide	[no description available]	medium	3
nickel	[no description available]	medium	1	metal allergen; nickel group element atom	epitope; micronutrient
sirolimus	[no description available]	medium	3	antibiotic antifungal drug; cyclic acetal; cyclic ketone; ether; macrolide lactam; organic heterotricyclic compound; secondary alcohol	antibacterial drug; anticoronaviral agent; antineoplastic agent; bacterial metabolite; geroprotector; immunosuppressive agent; mTOR inhibitor
tacrolimus	[no description available]	medium	1	macrolide lactam	bacterial metabolite; immunosuppressive agent
cholecystokinin	[no description available]	medium	2
ethylmaleimide	[no description available]	medium	2	maleimides	anticoronaviral agent; EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor; EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor; EC 2.7.1.1 (hexokinase) inhibitor
cobalt	[no description available]	medium	1	cobalt group element atom; metal allergen	micronutrient
isethionic acid	[no description available]	medium	1	alkanesulfonic acid	human metabolite
quinine	[no description available]	medium	1	cinchona alkaloid	antimalarial; muscle relaxant; non-narcotic analgesic
adenosine diphosphate	[no description available]	medium	1	adenosine 5'-phosphate; purine ribonucleoside 5'-diphosphate	fundamental metabolite; human metabolite
2-methylthio-atp	[no description available]	medium	1
lactic acid	[no description available]	medium	2	2-hydroxy monocarboxylic acid	algal metabolite; Daphnia magna metabolite
glycogen	[no description available]	medium	1
fructose 2,6-diphosphate	[no description available]	medium	2	D-fructofuranose 2,6-bisphosphate	human metabolite; mouse metabolite
copper gluconate	[no description available]	medium	1	organic molecular entity
gluconic acid	[no description available]	medium	1	gluconic acid	chelator; Penicillium metabolite
flag peptide	[no description available]	medium	1	peptide
n-(5-(2,3-dihydrobenzofuryl)sulfonyl)-n'-(3,4-dichlorophenyl)urea	[no description available]	medium	1
adenosine-5'-(n-ethylcarboxamide)	[no description available]	medium	1	adenosines; monocarboxylic acid amide	adenosine A1 receptor agonist; adenosine A2A receptor agonist; antineoplastic agent; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; vasodilator agent
adrenomedullin	[no description available]	medium	1
guanylin	[no description available]	medium	1
gentamicin	[no description available]	medium	1
1-(5-isoquinolinylsulfonyl)-3-methylpiperazine	[no description available]	medium	1
3-aminobenzamide	[no description available]	medium	2	benzamides; substituted aniline	EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
3,4-dihydro-5-methyl-1(2h)-isoquinolinone	[no description available]	medium	1	isoquinolines
2-amino-4-phosphonobutyric acid	[no description available]	medium	2
sphingosine	[no description available]	medium	1	sphing-4-enine	human metabolite; mouse metabolite
n-acetylsphingosine	[no description available]	medium	1	N-acylsphingosine
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	[no description available]	medium	2
cilostazol	[no description available]	medium	1	lactam; tetrazoles	anticoagulant; bronchodilator agent; EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor; fibrin modulating drug; neuroprotective agent; platelet aggregation inhibitor; vasodilator agent
n-formylmethionine leucyl-phenylalanine	[no description available]	medium	1	tripeptide
fenamic acid	[no description available]	medium	3	aminobenzoic acid; secondary amino compound	membrane transport modulator
phlorhizin	[no description available]	medium	1	aryl beta-D-glucoside; dihydrochalcones; monosaccharide derivative	antioxidant; plant metabolite
cariporide	[no description available]	medium	1
5-dimethylamiloride	[no description available]	medium	1
doxazosin	[no description available]	medium	1	aromatic amine; benzodioxine; monocarboxylic acid amide; N-acylpiperazine; N-arylpiperazine; quinazolines	alpha-adrenergic antagonist; antihyperplasia drug; antihypertensive agent; antineoplastic agent; vasodilator agent
terazosin	[no description available]	medium	1	furans; piperazines; primary amino compound; quinazolines	alpha-adrenergic antagonist; antihypertensive agent; antineoplastic agent
glucagon-like peptide 1	[no description available]	medium	2
enkephalin, d-penicillamine (2,5)-	[no description available]	medium	2	heterodetic cyclic peptide	delta-opioid receptor agonist
methionine	[no description available]	medium	3	aspartate family amino acid; L-alpha-amino acid; methionine zwitterion; methionine; proteinogenic amino acid	antidote to paracetamol poisoning; human metabolite; micronutrient; mouse metabolite; nutraceutical
peptide elongation factor 2	[no description available]	medium	2
transforming growth factor alpha	[no description available]	medium	1
1,3-dipropyl-8-cyclopentylxanthine	[no description available]	medium	1	oxopurine	adenosine A1 receptor antagonist; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
melatonin	[no description available]	medium	1	acetamides; tryptamines	anticonvulsant; central nervous system depressant; geroprotector; hormone; human metabolite; immunological adjuvant; mouse metabolite; radical scavenger
bicuculline	[no description available]	medium	1	benzylisoquinoline alkaloid; isoquinoline alkaloid; isoquinolines	agrochemical; central nervous system stimulant; GABA-gated chloride channel antagonist; GABAA receptor antagonist; neurotoxin
probucol	[no description available]	medium	1	dithioketal; polyphenol	anti-inflammatory drug; anticholesteremic drug; antilipemic drug; antioxidant; cardiovascular drug
8-bromoadenosine-3',5'-cyclic monophosphorothioate	[no description available]	medium	2
ucn 1028 c	[no description available]	medium	1
bisindolylmaleimide i	[no description available]	medium	2
rolipram	[no description available]	medium	2	pyrrolidin-2-ones	antidepressant; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
dextromethorphan	[no description available]	medium	1	6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene	antitussive; environmental contaminant; neurotoxin; NMDA receptor antagonist; oneirogen; prodrug; xenobiotic
ribose	[no description available]	medium	1	D-ribose; ribopyranose
pteridines	[no description available]	medium	1	azaarene; mancude organic heterobicyclic parent; ortho-fused heteroarene; pteridines
6-methoxy-n-(3-sulfopropyl)quinolinium	[no description available]	medium	1
thymidine	[no description available]	medium	1	pyrimidine 2'-deoxyribonucleoside	Escherichia coli metabolite; human metabolite; metabolite; mouse metabolite
glutamine	[no description available]	medium	1	amino acid zwitterion; glutamine family amino acid; glutamine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid	EC 1.14.13.39 (nitric oxide synthase) inhibitor; Escherichia coli metabolite; human metabolite; metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite
gold	[no description available]	medium	1	copper group element atom; elemental gold
medroxyprogesterone acetate	[no description available]	medium	1	20-oxo steroid; 3-oxo-Delta(4) steroid; acetate ester; corticosteroid; steroid ester	adjuvant; androgen; antineoplastic agent; antioxidant; female contraceptive drug; inhibitor; progestin; synthetic oral contraceptive
sk&f-38393	[no description available]	medium	3	benzazepine; catechols; secondary amino compound
ibuprofen	[no description available]	medium	1	monocarboxylic acid	antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; environmental contaminant; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug; radical scavenger; xenobiotic
aspirin	[no description available]	medium	1	benzoic acids; phenyl acetates; salicylates	anticoagulant; antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; EC 1.1.1.188 (prostaglandin-F synthase) inhibitor; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug; plant activator; platelet aggregation inhibitor; prostaglandin antagonist; teratogenic agent
fentanyl	[no description available]	medium	2	anilide; monocarboxylic acid amide; piperidines	adjuvant; anaesthesia adjuvant; anaesthetic; intravenous anaesthetic; mu-opioid receptor agonist; opioid analgesic
u 0126	[no description available]	medium	1	aryl sulfide; dinitrile; enamine; substituted aniline	antineoplastic agent; antioxidant; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; osteogenesis regulator; vasoconstrictor agent
2-chloro-n(6)cyclopentyladenosine	[no description available]	medium	1
niflumic acid	[no description available]	medium	1	aromatic carboxylic acid; pyridines
8-cyclopentyl-1,3-dimethylxanthine	[no description available]	medium	2	oxopurine
snx 230	[no description available]	medium	1
phenylalanine	[no description available]	medium	1	amino acid zwitterion; erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid; phenylalanine; proteinogenic amino acid	algal metabolite; EC 3.1.3.1 (alkaline phosphatase) inhibitor; Escherichia coli metabolite; human xenobiotic metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
spermine	[no description available]	medium	1	polyazaalkane; tetramine	antioxidant; fundamental metabolite; immunosuppressive agent
cesium chloride	[no description available]	medium	1	inorganic caesium salt; inorganic chloride	phase-transfer catalyst; vasoconstrictor agent
bromide	[no description available]	medium	1	halide anion; monoatomic bromine
nonanal	[no description available]	medium	1	medium-chain fatty aldehyde; n-alkanal; saturated fatty aldehyde	human metabolite; plant metabolite
4-hydroxy-2-nonenal	[no description available]	medium	2	4-hydroxynon-2-enal; 4-hydroxynonenal
sb 203580	[no description available]	medium	2	imidazoles; monofluorobenzenes; pyridines; sulfoxide	EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; geroprotector; Hsp90 inhibitor; neuroprotective agent
4,4'-dinitro-2,2'-stilbenedisulfonic acid	[no description available]	medium	1	4,4'-dinitrostilbene-2,2'-disulfonic acid
stilbenes	[no description available]	medium	1	stilbene
alpha,beta-methyleneadenosine 5'-triphosphate	[no description available]	medium	1	nucleoside triphosphate analogue
erbstatin	[no description available]	medium	1
lysine	[no description available]	medium	1	aspartate family amino acid; L-alpha-amino acid zwitterion; L-alpha-amino acid; lysine; organic molecular entity; proteinogenic amino acid	algal metabolite; anticonvulsant; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
arginine	[no description available]	medium	2	arginine; glutamine family amino acid; L-alpha-amino acid; proteinogenic amino acid	biomarker; Escherichia coli metabolite; micronutrient; mouse metabolite; nutraceutical
brefeldin a	[no description available]	medium	1	macrolide antibiotic	Penicillium metabolite
primaquine	[no description available]	medium	1	aminoquinoline; aromatic ether; N-substituted diamine	antimalarial
phytic acid	[no description available]	medium	1	inositol phosphate
nimodipine	[no description available]	medium	1	2-methoxyethyl ester; C-nitro compound; dicarboxylic acids and O-substituted derivatives; diester; dihydropyridine; isopropyl ester	antihypertensive agent; calcium channel blocker; cardiovascular drug; vasodilator agent
fluo-3	[no description available]	medium	1	xanthene dye	fluorochrome
xanthenes	[no description available]	medium	2	xanthene
spironolactone	[no description available]	medium	1	3-oxo-Delta(4) steroid; oxaspiro compound; steroid lactone; thioester	aldosterone antagonist; antihypertensive agent; diuretic; environmental contaminant; xenobiotic
lactoferrin	[no description available]	medium	1
trequinsin	[no description available]	medium	1	pyridopyrimidine
pepstatin	[no description available]	medium	1	pentapeptide; secondary carboxamide	bacterial metabolite; EC 3.4.23.* (aspartic endopeptidase) inhibitor
leupeptin	[no description available]	medium	1	aldehyde; tripeptide	bacterial metabolite; calpain inhibitor; cathepsin B inhibitor; EC 3.4.21.4 (trypsin) inhibitor; serine protease inhibitor
fluorine	[no description available]	medium	1	diatomic fluorine; gas molecular entity	NMR chemical shift reference compound
guanosine 5'-o-(3-thiotriphosphate)	[no description available]	medium	2	nucleoside triphosphate analogue
tetrafluoroaluminate	[no description available]	medium	1
sodium iodide	[no description available]	medium	1	inorganic sodium salt; iodide salt
kemptide	[no description available]	medium	1
sorbitol	[no description available]	medium	1	glucitol	cathartic; Escherichia coli metabolite; food humectant; human metabolite; laxative; metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite; sweetening agent
zy 17617b	[no description available]	medium	1
calmidazolium	[no description available]	medium	1	imidazolium ion	apoptosis inducer; calmodulin antagonist
benzmetanide	[no description available]	medium	1
zaprinast	[no description available]	medium	1	triazolopyrimidines
demecolcine	[no description available]	medium	1	alkaloid; secondary amino compound	antineoplastic agent; microtubule-destabilising agent
fenoldopam	[no description available]	medium	1	benzazepine	alpha-adrenergic agonist; antihypertensive agent; dopamine agonist; dopaminergic antagonist; vasodilator agent
guanylyl imidodiphosphate	[no description available]	medium	1	nucleoside triphosphate analogue
androstenedione	[no description available]	medium	1	17-oxo steroid; 3-oxo-Delta(4) steroid; androstanoid	androgen; Daphnia magna metabolite; human metabolite; mouse metabolite
beta-endorphin	[no description available]	medium	1
gallic acid	[no description available]	medium	1	trihydroxybenzoic acid	antineoplastic agent; antioxidant; apoptosis inducer; astringent; cyclooxygenase 2 inhibitor; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; geroprotector; human xenobiotic metabolite; plant metabolite
8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate	[no description available]	medium	1	trihydroxybenzoic acid
octopamine	[no description available]	medium	1	phenylethanolamines; tyramines	neurotransmitter
phosphothreonine	[no description available]	medium	1	L-threonine derivative; non-proteinogenic L-alpha-amino acid; O-phosphoamino acid	Escherichia coli metabolite
enkephalin, methionine	[no description available]	medium	1
sufentanil	[no description available]	medium	1	anilide; ether; piperidines; thiophenes	anaesthesia adjuvant; intravenous anaesthetic; mu-opioid receptor agonist; opioid analgesic
dynorphins	[no description available]	medium	1
baclofen	[no description available]	medium	1	amino acid zwitterion; gamma-amino acid; monocarboxylic acid; monochlorobenzenes; primary amino compound	central nervous system depressant; GABA agonist; muscle relaxant
dihydropyridines	[no description available]	medium	1
quinacrine	[no description available]	medium	1	acridines; aromatic ether; organochlorine compound; tertiary amino compound	antimalarial; EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
ah 6809	[no description available]	medium	1	xanthones
beta-escin	[no description available]	medium	1
rubidium	[no description available]	medium	1	alkali metal atom
nad	[no description available]	medium	1	organophosphate oxoanion	cofactor; human metabolite; hydrogen acceptor; Saccharomyces cerevisiae metabolite
vanadates	[no description available]	medium	1	trivalent inorganic anion; vanadium oxoanion	EC 3.1.3.1 (alkaline phosphatase) inhibitor; EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor; EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor; EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
glycine	[no description available]	medium	1	alpha-amino acid; amino acid zwitterion; proteinogenic amino acid; serine family amino acid	EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor; fundamental metabolite; hepatoprotective agent; micronutrient; neurotransmitter; NMDA receptor agonist; nutraceutical
phorbol	[no description available]	medium	1	cyclic ketone; enone; tertiary alcohol; tertiary alpha-hydroxy ketone; tetracyclic diterpenoid
phorbols	[no description available]	medium	2	diterpene; terpenoid fundamental parent
2-aminopurine	[no description available]	medium	1	2-aminopurines; nucleobase analogue	antimetabolite
thioguanine anhydrous	[no description available]	medium	1	2-aminopurines	anticoronaviral agent; antimetabolite; antineoplastic agent
meglumine	[no description available]	medium	1	hexosamine; secondary amino compound
zinc sulfate	[no description available]	medium	1	metal sulfate; zinc molecular entity	fertilizer
metallothionein	[no description available]	medium	3
apomorphine	[no description available]	medium	1	aporphine alkaloid	alpha-adrenergic drug; antidyskinesia agent; antiparkinson drug; dopamine agonist; emetic; serotonergic drug
nisoldipine	[no description available]	medium	1	C-nitro compound; dicarboxylic acids and O-substituted derivatives; diester; dihydropyridine; methyl ester
pilocarpine	[no description available]	medium	1	pilocarpine	antiglaucoma drug
n-methylscopolamine	[no description available]	medium	1
preproenkephalin	[no description available]	medium	1
2-tetradecylglycidic acid	[no description available]	medium	1
aluminum fluoride	[no description available]	medium	1	aluminium coordination entity
neurotensin	[no description available]	medium	1	peptide hormone	human metabolite; mitogen; neurotransmitter; vulnerary
anisomycin	[no description available]	medium	1	monohydroxypyrrolidine; organonitrogen heterocyclic antibiotic	anticoronaviral agent; antimicrobial agent; antineoplastic agent; antiparasitic agent; bacterial metabolite; DNA synthesis inhibitor; protein synthesis inhibitor
triiodothyronine	[no description available]	medium	2	2-halophenol; amino acid zwitterion; iodophenol; iodothyronine	human metabolite; mouse metabolite; thyroid hormone
inositol	[no description available]	medium	1	cyclitol; hexol
cilostamide	[no description available]	medium	1	quinolines
6-ketoprostaglandin f1 alpha	[no description available]	medium	1	prostaglandins Falpha	human metabolite; mouse metabolite
carbostyril	[no description available]	medium	1	monohydroxyquinoline; quinolone	bacterial xenobiotic metabolite
cadmium chloride	[no description available]	medium	1	cadmium coordination entity
cadmium	[no description available]	medium	1	cadmium molecular entity; zinc group element atom
phosphorylethanolamine	[no description available]	medium	1	phosphoethanolamine; primary amino compound	algal metabolite; human metabolite; mouse metabolite
amanitins	[no description available]	medium	2
adenosine diphosphate ribose	[no description available]	medium	1	ADP-sugar	Escherichia coli metabolite; mouse metabolite
insulin, desoctapeptide-	[no description available]	medium	1
phosphorylcholine	[no description available]	medium	1	phosphocholines	allergen; epitope; hapten; human metabolite; mouse metabolite
ovalbumin	[no description available]	medium	1
caseins	[no description available]	medium	1
phallacidin	[no description available]	medium	1	homodetic cyclic peptide
7-nitrobenz-2-oxa-1,3-diazole-phallacidin	[no description available]	medium	1
raffinose	[no description available]	medium	1	raffinose family oligosaccharide; trisaccharide	mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
w 7	[no description available]	medium	1
thromboxane b2	[no description available]	medium	1	thromboxanes B	human metabolite; mouse metabolite
monobutyryl cyclic amp	[no description available]	medium	0	3',5'-cyclic purine nucleotide; adenyl ribonucleotide; butanamides	protein kinase agonist
bucladesine	[no description available]	low	0	3',5'-cyclic purine nucleotide; butanamides; butyrate ester	agonist; cardiotonic drug; vasodilator agent
2'-deoxy cyclic amp	[no description available]	low	0	3',5'-cyclic purine nucleotide	Saccharomyces cerevisiae metabolite
cyclic imp	[no description available]	low	0	3',5'-cyclic purine nucleotide; nucleoside 3',5'-cyclic phosphate	mammalian metabolite; Saccharomyces cerevisiae metabolite
8-nitroguanosine 3',5'-cyclic monophosphate	[no description available]	low	0	3',5'-cyclic purine nucleotide; C-nitro compound	biomarker; Brassica napus metabolite; human metabolite; signalling molecule
cyclic diadenosine phosphate	[no description available]	low	0	adenyl ribonucleotide; cyclic purine dinucleotide	Mycoplasma genitalium metabolite
cyclic guanosine monophosphate-adenosine monophosphate	[no description available]	low	0	adenyl ribonucleotide; cyclic purine dinucleotide; guanyl ribonucleotide
chloroacetaldehyde	[no description available]	low	0	organochlorine compound
3-chloroalanine	[no description available]	low	0	chloroalanine; non-proteinogenic alpha-amino acid; organochlorine compound
chlordecone	[no description available]	low	0	cyclic ketone; organochlorine compound	insecticide; persistent organic pollutant
4-(2,4-dichlorophenoxy)butyric acid	[no description available]	low	0	aromatic ether; monocarboxylic acid; organochlorine compound	agrochemical; phenoxy herbicide; synthetic auxin
2-hydroxysaclofen	[no description available]	low	0	organochlorine compound
3,4-dichloroisocoumarin	[no description available]	low	0	isocoumarins; organochlorine compound	geroprotector; serine protease inhibitor
5-(n,n-hexamethylene)amiloride	[no description available]	low	0	aromatic amine; azepanes; guanidines; monocarboxylic acid amide; organochlorine compound; pyrazines	antineoplastic agent; apoptosis inducer; odorant receptor antagonist; sodium channel blocker
ethylisopropylamiloride	[no description available]	low	0	aromatic amine; guanidines; monocarboxylic acid amide; organochlorine compound; pyrazines; tertiary amino compound	anti-arrhythmia drug; neuroprotective agent; sodium channel blocker
7-chlorokynurenic acid	[no description available]	low	0	organochlorine compound; quinolinemonocarboxylic acid	neuroprotective agent; NMDA receptor antagonist
acetochlor	[no description available]	low	0	aromatic amide; monocarboxylic acid amide; organochlorine compound	environmental contaminant; herbicide; xenobiotic
alachlor	[no description available]	low	0	aromatic amide; monocarboxylic acid amide; organochlorine compound	environmental contaminant; herbicide; xenobiotic
alprazolam	[no description available]	low	0	organochlorine compound; triazolobenzodiazepine	anticonvulsant; anxiolytic drug; GABA agonist; muscle relaxant; sedative; xenobiotic
amodiaquine	[no description available]	low	0	aminoquinoline; organochlorine compound; phenols; secondary amino compound; tertiary amino compound	anticoronaviral agent; antimalarial; drug allergen; EC 2.1.1.8 (histamine N-methyltransferase) inhibitor; non-steroidal anti-inflammatory drug; prodrug
benzylhydrochlorothiazide	[no description available]	low	0	benzenes; benzothiadiazine; organochlorine compound; secondary amino compound; sulfonamide
carmustine	[no description available]	low	0	N-nitrosoureas; organochlorine compound	alkylating agent; antineoplastic agent
carprofen	[no description available]	low	0	carbazoles; organochlorine compound	EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-steroidal anti-inflammatory drug; photosensitizing agent
cgs 15943	[no description available]	low	0	aromatic amine; biaryl; furans; organochlorine compound; primary amino compound; quinazolines; triazoloquinazoline	adenosine A1 receptor antagonist; adenosine A2A receptor antagonist; antineoplastic agent; central nervous system stimulant
chloral hydrate	[no description available]	low	0	aldehyde hydrate; ethanediol; organochlorine compound	general anaesthetic; mouse metabolite; sedative; xenobiotic
chlorambucil	[no description available]	low	0	aromatic amine; monocarboxylic acid; nitrogen mustard; organochlorine compound; tertiary amino compound	alkylating agent; antineoplastic agent; carcinogenic agent; drug allergen; immunosuppressive agent
chloroquine	[no description available]	low	0	aminoquinoline; organochlorine compound; secondary amino compound; tertiary amino compound	anticoronaviral agent; antimalarial; antirheumatic drug; autophagy inhibitor; dermatologic drug
chloroxine	[no description available]	low	0	monohydroxyquinoline; organochlorine compound	antibacterial agent; antifungal drug; antiseborrheic
chlorzoxazone	[no description available]	low	0	1,3-benzoxazoles; heteroaryl hydroxy compound; organochlorine compound	muscle relaxant; sedative
ciprofibrate	[no description available]	low	0	cyclopropanes; monocarboxylic acid; organochlorine compound	antilipemic drug
clioquinol	[no description available]	low	0	monohydroxyquinoline; organochlorine compound; organoiodine compound	antibacterial agent; antifungal agent; antimicrobial agent; antineoplastic agent; antiprotozoal drug; chelator; copper chelator
clobazam	[no description available]	low	0	1,4-benzodiazepinone; organochlorine compound	anticonvulsant; anxiolytic drug; GABA modulator
clobenpropit	[no description available]	low	0	imidazoles; imidothiocarbamic ester; organochlorine compound	H3-receptor antagonist; H4-receptor agonist
cloxyquin	[no description available]	low	0	organochlorine compound; quinolines
coumaphos	[no description available]	low	0	organic thiophosphate; organochlorine compound; organothiophosphate insecticide	acaricide; agrochemical; antinematodal drug; avicide; EC 3.1.1.8 (cholinesterase) inhibitor
cypermethrin	[no description available]	low	0	aromatic ether; cyclopropanecarboxylate ester; nitrile; organochlorine compound	agrochemical; molluscicide; pyrethroid ester acaricide; pyrethroid ester insecticide
nordazepam	[no description available]	low	0	1,4-benzodiazepinone; organochlorine compound	anticonvulsant; anxiolytic drug; GABA modulator; human metabolite; sedative
diazepam	[no description available]	low	0	1,4-benzodiazepinone; organochlorine compound	anticonvulsant; anxiolytic drug; environmental contaminant; sedative; xenobiotic
diazoxide	[no description available]	low	0	benzothiadiazine; organochlorine compound; sulfone	antihypertensive agent; beta-adrenergic agonist; bronchodilator agent; cardiotonic drug; diuretic; K-ATP channel agonist; sodium channel blocker; sympathomimetic agent; vasodilator agent
enflurane	[no description available]	low	0	ether; organochlorine compound; organofluorine compound	anaesthetic
fludiazepam	[no description available]	low	0	1,4-benzodiazepinone; organochlorine compound; organofluorine compound	anxiolytic drug
flurazepam	[no description available]	low	0	1,4-benzodiazepinone; monofluorobenzenes; organochlorine compound; tertiary amino compound	anticonvulsant; anxiolytic drug; GABAA receptor agonist; sedative
glafenine	[no description available]	low	0	aminoquinoline; carboxylic ester; glycol; organochlorine compound; secondary amino compound	inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug
halothane	[no description available]	low	0	haloalkane; organobromine compound; organochlorine compound; organofluorine compound	inhalation anaesthetic
hydrochlorothiazide	[no description available]	low	0	benzothiadiazine; organochlorine compound; sulfonamide	antihypertensive agent; diuretic; environmental contaminant; xenobiotic
hydroxychloroquine	[no description available]	low	0	aminoquinoline; organochlorine compound; primary alcohol; secondary amino compound; tertiary amino compound	anticoronaviral agent; antimalarial; antirheumatic drug; dermatologic drug
indapamide	[no description available]	low	0	indoles; organochlorine compound; sulfonamide	antihypertensive agent; diuretic
lomustine	[no description available]	low	0	N-nitrosoureas; organochlorine compound	alkylating agent; antineoplastic agent
loratadine	[no description available]	low	0	benzocycloheptapyridine; ethyl ester; N-acylpiperidine; organochlorine compound; tertiary carboxamide	anti-allergic agent; cholinergic antagonist; geroprotector; H1-receptor antagonist
mechlorethamine	[no description available]	low	0	nitrogen mustard; organochlorine compound	alkylating agent
meclofenamic acid	[no description available]	low	0	aminobenzoic acid; organochlorine compound; secondary amino compound	analgesic; anticonvulsant; antineoplastic agent; antipyretic; antirheumatic drug; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-steroidal anti-inflammatory drug
methoxyflurane	[no description available]	low	0	ether; organochlorine compound; organofluorine compound	hepatotoxic agent; inhalation anaesthetic; nephrotoxic agent; non-narcotic analgesic
metolachlor	[no description available]	low	0	aromatic amide; benzenes; ether; organochlorine compound
metolazone	[no description available]	low	0	organochlorine compound; quinazolines; sulfonamide	antihypertensive agent; diuretic; ion transport inhibitor
midazolam	[no description available]	low	0	imidazobenzodiazepine; monofluorobenzenes; organochlorine compound	anticonvulsant; antineoplastic agent; anxiolytic drug; apoptosis inducer; central nervous system depressant; GABAA receptor agonist; general anaesthetic; muscle relaxant; sedative
mosapramine	[no description available]	low	0	azaspiro compound; dibenzoazepine; organochlorine compound; tertiary amino compound
n-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide	[no description available]	low	0	naphthalenes; organochlorine compound; primary amino compound; sulfonamide
naled	[no description available]	low	0	dialkyl phosphate; organobromine compound; organochlorine compound; organophosphate insecticide	acaricide; agrochemical; antibacterial agent; antifungal agent; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor
oxazepam	[no description available]	low	0	1,4-benzodiazepinone; organochlorine compound	anxiolytic drug; environmental contaminant; xenobiotic
perphenazine	[no description available]	low	0	N-(2-hydroxyethyl)piperazine; N-alkylpiperazine; organochlorine compound; phenothiazines	antiemetic; dopaminergic antagonist; phenothiazine antipsychotic drug
prochlorperazine	[no description available]	low	0	N-alkylpiperazine; N-methylpiperazine; organochlorine compound; phenothiazines	alpha-adrenergic antagonist; antiemetic; cholinergic antagonist; dopamine receptor D2 antagonist; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; first generation antipsychotic
propachlor	[no description available]	low	0	anilide; monocarboxylic acid amide; organochlorine compound	environmental contaminant; herbicide; xenobiotic
7-chloro-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol	[no description available]	low	0	benzazepine; organochlorine compound; tertiary amino compound	dopaminergic antagonist
semustine	[no description available]	low	0	N-nitrosoureas; organochlorine compound	alkylating agent; antineoplastic agent; carcinogenic agent
sibutramine	[no description available]	low	0	organochlorine compound; tertiary amino compound	anti-obesity agent; serotonin uptake inhibitor
tulobuterol	[no description available]	low	0	organochlorine compound
pirinixic acid	[no description available]	low	0	aryl sulfide; organochlorine compound; pyrimidines
trichlorfon	[no description available]	low	0	organic phosphonate; organochlorine compound; phosphonic ester	agrochemical; anthelminthic drug; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; insecticide
chloramphenicol	[no description available]	low	0	C-nitro compound; carboxamide; diol; organochlorine compound	antibacterial drug; antimicrobial agent; Escherichia coli metabolite; geroprotector; Mycoplasma genitalium metabolite; protein synthesis inhibitor
chlorquinaldol	[no description available]	low	0	monohydroxyquinoline; organochlorine compound	antibacterial drug; antiprotozoal drug; antiseptic drug
1,1-dichloroethane	[no description available]	low	0	organochlorine compound
trichloroacetaldehyde	[no description available]	low	0	aldehyde; organochlorine compound	mouse metabolite
trichloroacetic acid	[no description available]	low	0	monocarboxylic acid; organochlorine compound	carcinogenic agent; metabolite; mouse metabolite
chloropicrin	[no description available]	low	0	C-nitro compound; one-carbon compound; organochlorine compound	antifungal agrochemical; fumigant insecticide; nematicide
chloropentafluoroethane	[no description available]	low	0	organochlorine compound; organofluorine compound
dichloroacetaldehyde	[no description available]	low	0	organochlorine compound
dichloroacetic acid	[no description available]	low	0	monocarboxylic acid; organochlorine compound	astringent; marine metabolite
sulfachlorpyridazine	[no description available]	low	0	organochlorine compound; pyridazines; sulfonamide	antibacterial drug; drug allergen; EC 2.5.1.15 (dihydropteroate synthase) inhibitor
thiopropazate	[no description available]	low	0	acetate ester; N-alkylpiperazine; organochlorine compound; phenothiazines	dopaminergic antagonist; phenothiazine antipsychotic drug
hexachlorobutadiene	[no description available]	low	0	organochlorine compound
symclosene	[no description available]	low	0	1,3,5-triazinanes; organochlorine compound
3,3'-dichlorobenzidine	[no description available]	low	0	biphenyls; monochlorobenzenes; organochlorine compound
1,2-dibromo-3-chloropropane	[no description available]	low	0	organochlorine compound
1,2,3-trichloropropane	[no description available]	low	0	organochlorine compound
1,3-dichloro-2-propanol	[no description available]	low	0	organochlorine compound; secondary alcohol	cross-linking reagent; protic solvent
benzotrichloride	[no description available]	low	0	benzenes; organochlorine compound; volatile organic compound	carcinogenic agent
epichlorohydrin	[no description available]	low	0	epoxide; organochlorine compound
1-bromo-2-chloroethane	[no description available]	low	0	haloalkane; organobromine compound; organochlorine compound	mutagen
allyl chloride	[no description available]	low	0	organochlorine compound
cyanuric chloride	[no description available]	low	0	chloro-1,3,5-triazine; organochlorine compound	cross-linking reagent
chlorendic acid	[no description available]	low	0	bridged compound; dicarboxylic acid; organochlorine compound	carcinogenic agent
tris(chloroethyl)phosphate	[no description available]	low	0	organochlorine compound; trialkyl phosphate
chloranil	[no description available]	low	0	1,4-benzoquinones; organochlorine compound	EC 2.7.1.33 (pantothenate kinase) inhibitor; metabolite
captan	[no description available]	low	0	isoindoles; organochlorine compound; organosulfur compound; phthalimide fungicide	antifungal agrochemical
folpet	[no description available]	low	0	organochlorine compound; organosulfur compound; phthalimide fungicide	antifungal agrochemical
trichloronate	[no description available]	low	0	organochlorine compound
bromochlorodifluoromethane	[no description available]	low	0	one-carbon compound; organobromine compound; organochlorine compound; organofluorine compound
metofenazate	[no description available]	low	0	N-alkylpiperazine; organochlorine compound; phenothiazines
mustard gas	[no description available]	low	0	ethyl sulfide; organochlorine compound	alkylating agent; carcinogenic agent; vesicant
1-chloro-2-methylpropene	[no description available]	low	0	organochlorine compound
8-chlorotheophylline	[no description available]	low	0	organochlorine compound; purines	central nervous system stimulant
1,3-dichloroacetone	[no description available]	low	0	ketone; organochlorine compound
bis(chloromethyl) ether	[no description available]	low	0	ether; organochlorine compound	alkylating agent; carcinogenic agent
trichloroacetonitrile	[no description available]	low	0	aliphatic nitrile; organochlorine compound
3-chloro-2-methylprop-1-ene	[no description available]	low	0	organochlorine compound
2,6-dichlorobenzoquinone	[no description available]	low	0	1,4-benzoquinones; organochlorine compound	carcinogenic agent; poison
n-dichlorofluoromethylthio-n',n'-dimethyl-n-p-tolylsulfamide	[no description available]	low	0	organochlorine compound; organofluorine compound; phenylsulfamide fungicide; sulfamides	antifungal agrochemical; genotoxin
lormetazepam	[no description available]	low	0	1,4-benzodiazepinone; organochlorine compound	sedative
2-chloro-1,4-naphthoquinone	[no description available]	low	0	1,4-naphthoquinones; organochlorine compound
chlordecone alcohol	[no description available]	low	0	organochlorine compound
dichlofluanid	[no description available]	low	0	organochlorine compound; organofluorine compound; phenylsulfamide fungicide; sulfamides	acaricide; antifungal agrochemical
win 18446	[no description available]	low	0	organochlorine compound; secondary carboxamide	EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor
pyrazon	[no description available]	low	0	benzenes; organochlorine compound; primary amino compound; pyridazinone	environmental contaminant; herbicide; xenobiotic
bromocyclen	[no description available]	low	0	organochlorine compound
5-chlorouracil	[no description available]	low	0	organochlorine compound
dienochlor	[no description available]	low	0	organochlorine compound
captafol	[no description available]	low	0	isoindoles; organochlorine compound; organosulfur compound; phthalimide fungicide	antifungal agrochemical
etridiazol	[no description available]	low	0	aromatic ether; organochlorine compound; thiadiazole antifungal agent; thiadiazoles	antifungal agrochemical; nitrification inhibitor
o-chlorobenzylidenemalonitrile	[no description available]	low	0	organochlorine compound
diloxanide furoate	[no description available]	low	0	carboxylic ester; furans; organochlorine compound; tertiary carboxamide	antiamoebic agent; prodrug
cladribine	[no description available]	low	0	organochlorine compound; purine 2'-deoxyribonucleoside	antineoplastic agent; immunosuppressive agent
dichloroacetylene	[no description available]	low	0	organochlorine compound
chloroethylene oxide	[no description available]	low	0	organochlorine compound
clodronic acid	[no description available]	low	0	1,1-bis(phosphonic acid); one-carbon compound; organochlorine compound	antineoplastic agent; bone density conservation agent
ornidazole	[no description available]	low	0	C-nitro compound; imidazoles; organochlorine compound; secondary alcohol	antiamoebic agent; antibacterial drug; antiinfective agent; antiprotozoal drug; antitrichomonal drug; epitope
acridine half-mustard	[no description available]	low	0	aminoacridines; aromatic ether; organochlorine compound; secondary amino compound	mutagen
didesethylflurazepam	[no description available]	low	0	1,4-benzodiazepinone; monofluorobenzenes; organochlorine compound; primary amino compound	anticonvulsant; anxiolytic drug; drug metabolite; GABAA receptor agonist; sedative
clonixin	[no description available]	low	0	aminopyridine; organochlorine compound; pyridinemonocarboxylic acid	antipyretic; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; lipoxygenase inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug; platelet aggregation inhibitor; vasodilator agent
chlorodibromomethane	[no description available]	low	0	organochlorine compound
1-chloro-2-propanol	[no description available]	low	0	organochlorine compound; secondary alcohol
butachlor	[no description available]	low	0	aromatic amide; organochlorine compound; tertiary carboxamide	environmental contaminant; herbicide; xenobiotic
pyoluteorin	[no description available]	low	0	aromatic ketone; beta-hydroxy ketone; diol; organochlorine compound; organochlorine pesticide; polyketide; pyrroles; resorcinols	antibacterial agent; antifungal agent; apoptosis inducer; bacterial metabolite; marine metabolite
5-chloro-2-methyl-4-isothiazolin-3-one	[no description available]	low	0	1,2-thiazoles; organochlorine compound	antimicrobial agent; environmental contaminant; xenobiotic
triforine	[no description available]	low	0	amide fungicide; formamides; N-alkylpiperazine; organochlorine compound	allergen; antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
oxamethacin	[no description available]	low	0	aromatic ether; hydroxamic acid; N-acylindole; organochlorine compound	EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug
norflurazone	[no description available]	low	0	(trifluoromethyl)benzenes; organochlorine compound; pyridazinone; secondary amino compound	agrochemical; carotenoid biosynthesis inhibitor; herbicide
octachlorostyrene	[no description available]	low	0	organochlorine compound
perfosfamide	[no description available]	low	0	nitrogen mustard; organochlorine compound; peroxol; phosphorodiamide	alkylating agent; antineoplastic agent; drug allergen; immunosuppressive agent; metabolite
nimustine	[no description available]	low	0	aminopyrimidine; N-nitrosoureas; organochlorine compound	alkylating agent; antineoplastic agent
tiamenidine	[no description available]	low	0	organochlorine compound
acifluorfen	[no description available]	low	0	aromatic ether; benzoic acids; C-nitro compound; monocarboxylic acid; organochlorine compound; organofluorine compound	agrochemical; EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor; herbicide
metazachlor	[no description available]	low	0	aromatic amide; organochlorine compound; pyrazoles	environmental contaminant; herbicide; xenobiotic
4,5-amino-3,5-dichloro-6-fluoro-2-pyridinyloxyacetic acid	[no description available]	low	0	aminopyridine; aromatic ether; monocarboxylic acid; organochlorine compound; organofluorine compound	environmental contaminant; herbicide; xenobiotic
haloxyfop	[no description available]	low	0	aromatic ether; monocarboxylic acid; organochlorine compound; organofluorine compound; pyridines
quizalofop-ethyl	[no description available]	low	0	aromatic ether; ethyl ester; organochlorine compound; quinoxaline derivative
cicletanine	[no description available]	low	0	organochlorine compound
lonapalene	[no description available]	low	0	naphthalenes; organochlorine compound
sertindole	[no description available]	low	0	heteroarylpiperidine; imidazolidinone; organochlorine compound; organofluorine compound; phenylindole	alpha-adrenergic antagonist; H1-receptor antagonist; second generation antipsychotic; serotonergic antagonist
ziprasidone	[no description available]	low	0	1,2-benzisothiazole; indolones; organochlorine compound; piperazines	antipsychotic agent; dopaminergic antagonist; histamine antagonist; muscarinic antagonist; psychotropic drug; serotonergic antagonist
tiludronic acid	[no description available]	low	0	organochlorine compound
r 29148	[no description available]	low	0	organochlorine compound; oxazolidines; tertiary carboxamide	herbicide safener
heptenophos	[no description available]	low	0	organochlorine compound; organophosphate insecticide; trialkyl phosphate	acaricide; agrochemical; EC 3.1.1.7 (acetylcholinesterase) inhibitor
efavirenz	[no description available]	low	0	acetylenic compound; benzoxazine; cyclopropanes; organochlorine compound; organofluorine compound	antiviral drug; HIV-1 reverse transcriptase inhibitor
ro 5-3335	[no description available]	low	0	1,4-benzodiazepinone; organochlorine compound; pyrroles	anti-HIV-1 agent; antineoplastic agent; HIV-1 Tat inhibitor; RUNX1 inhibitor
5-bromo-4-chloro-3-indolyl beta-galactoside	[no description available]	low	0	beta-D-galactoside; D-aldohexose derivative; indolyl carbohydrate; organobromine compound; organochlorine compound	chromogenic compound
5-bromo-4-chloro-3-indoxyl phosphate	[no description available]	low	0	aryl phosphate; indoles; organobromine compound; organochlorine compound	chromogenic compound
z 424	[no description available]	low	0	organochlorine compound
tianeptine	[no description available]	low	0	dibenzothiazepine; monocarboxylic acid; organochlorine compound
trichlorosucrose	[no description available]	low	0	disaccharide derivative; organochlorine compound	environmental contaminant; sweetening agent; xenobiotic
clobuzarit	[no description available]	low	0	biphenyls; organochlorine compound
eberconazole	[no description available]	low	0	dibenzannulene; imidazoles; organochlorine compound
gr 117289	[no description available]	low	0	1-benzofurans; biaryl; imidazolyl carboxylic acid; monocarboxylic acid; organobromine compound; organochlorine compound; tetrazoles	angiotensin receptor antagonist; antihypertensive agent
rebeccamycin	[no description available]	low	0	indolocarbazole; N-glycosyl compound; organic heterohexacyclic compound; organochlorine compound
triasulfuron	[no description available]	low	0	1,3,5-triazines; aromatic ether; N-sulfonylurea; organochlorine compound	agrochemical; herbicide
4,5,6,7-tetrachloro-2-trifluoromethylbenzimidazole	[no description available]	low	0	organochlorine compound
3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid	[no description available]	low	0	organochlorine compound
raiser	[no description available]	low	0	(trifluoromethyl)benzenes; organochlorine compound; pyrrolidines	agrochemical; carotenoid biosynthesis inhibitor; herbicide
kathon 930	[no description available]	low	0	1,2-thiazoles; organochlorine compound	environmental contaminant; fungicide; xenobiotic
quinclorac	[no description available]	low	0	monocarboxylic acid; organochlorine compound; quinolinemonocarboxylic acid	agrochemical; herbicide; synthetic auxin
dimethenamid	[no description available]	low	0	aromatic amide; ether; organochlorine compound; thiophenes
fluxofenim	[no description available]	low	0	organochlorine compound
clodinafop-propargyl	[no description available]	low	0	aromatic ether; carboxylic ester; organochlorine compound; organofluorine compound; propyzamide; pyridines	agrochemical; EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor; herbicide
3-chlorolactate	[no description available]	low	0	2-hydroxy monocarboxylic acid; organochlorine compound
cloquintocet-mexyl	[no description available]	low	0	aromatic ether; carboxylic ester; organochlorine compound; quinolines
2,6-dichloroisonicotinic acid	[no description available]	low	0	monocarboxylic acid; organochlorine compound; pyridines	EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor
sporidesmin	[no description available]	low	0	aromatic ether; cyclic ketone; diketone; organic disulfide; organic heteropentacyclic compound; organochlorine compound; secondary alcohol; tertiary alcohol; tertiary amino compound	mycotoxin; Wnt signalling activator
4-hydroxycyclophosphamide	[no description available]	low	0	nitrogen mustard; organochlorine compound; phosphorodiamide	alkylating agent; metabolite
fotemustine	[no description available]	low	0	N-nitrosoureas; organic phosphonate; organochlorine compound
cyfluthrin	[no description available]	low	0	aromatic ether; cyclopropanecarboxylate ester; nitrile; organochlorine compound; organofluorine compound	agrochemical; pyrethroid ester insecticide
thiamethoxam	[no description available]	low	0	1,3-thiazoles; 2-nitroguanidine derivative; organochlorine compound; oxadiazane	antifeedant; carcinogenic agent; environmental contaminant; neonicotinoid insectide; xenobiotic
1-hydroxymethylmidazolam	[no description available]	low	0	aromatic primary alcohol; imidazobenzodiazepine; monofluorobenzenes; organochlorine compound	drug metabolite; human blood serum metabolite; human urinary metabolite
s-chloromethylglutathione	[no description available]	low	0	organochlorine compound; S-substituted glutathione	alkylating agent; bacterial xenobiotic metabolite; mouse metabolite
exp3174	[no description available]	low	0	biphenylyltetrazole; imidazoles; organochlorine compound	metabolite
florfenicol	[no description available]	low	0	organochlorine compound; organofluorine compound; secondary alcohol; secondary carboxamide; sulfone	antimicrobial agent
monochlorobimane	[no description available]	low	0	organochlorine compound; pyrazolopyrazole	fluorochrome
Prothioconazole-desthio	[no description available]	low	0	organochlorine compound
saclofen	[no description available]	low	0	organochlorine compound
piperaquine	[no description available]	low	0	aminoquinoline; N-arylpiperazine; organochlorine compound	antimalarial
mk 0663	[no description available]	low	0	bipyridines; organochlorine compound; sulfone	cyclooxygenase 2 inhibitor; non-steroidal anti-inflammatory drug
norketamine	[no description available]	low	0	organochlorine compound
7,8-dichloro-1,2,3,4-tetrahydroisoquinoline	[no description available]	low	0	isoquinolines; organochlorine compound
4-hydroxymidazolam	[no description available]	low	0	imidazobenzodiazepine; monofluorobenzenes; organic hydroxy compound; organochlorine compound	drug metabolite; human blood serum metabolite; human urinary metabolite
cki 7	[no description available]	low	0	isoquinolines; organochlorine compound; primary amino compound; sulfonamide	EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
6-bromo-3-(bromomethyl)-7-methyl-2,3,7-trichloro-1-octene	[no description available]	low	0	monoterpenoid; organobromine compound; organochlorine compound	algal metabolite; antineoplastic agent; marine metabolite
pyrrolomycin a	[no description available]	low	0	antibiotic antifungal agent; C-nitro compound; organochlorine compound; pyrroles	antibacterial agent; bacterial metabolite
sk&f 83959	[no description available]	low	0	benzazepine; catechols; organochlorine compound; tertiary amino compound	dopamine agonist
1-hydroxymethylmidazolam glucuronide	[no description available]	low	0	beta-D-glucosiduronic acid; imidazobenzodiazepine; monofluorobenzenes; monosaccharide derivative; organochlorine compound	drug metabolite; human blood serum metabolite; human urinary metabolite
cox 189	[no description available]	low	0	amino acid; monocarboxylic acid; organochlorine compound; organofluorine compound; secondary amino compound	cyclooxygenase 2 inhibitor; non-steroidal anti-inflammatory drug
pannarin	[no description available]	low	0	aldehyde; aromatic ether; depsidones; organic heterotricyclic compound; organochlorine compound; phenols	antimicrobial agent; antineoplastic agent; apoptosis inducer; lichen metabolite
5,6-dehydronorketamine	[no description available]	low	0	organochlorine compound
6-chloro-3,5-diaminopyrazine-3-carboxamide	[no description available]	low	0	organochlorine compound; pyrazines
quizalofop	[no description available]	low	0	aromatic ether; monocarboxylic acid; organochlorine compound; quinoxaline derivative
chloroorienticin b	[no description available]	low	0	cyclic ether; glycopeptide; heterodetic cyclic peptide; monosaccharide derivative; organochlorine compound; polyphenol	antimicrobial agent; bacterial metabolite
lapatinib	[no description available]	low	0	furans; organochlorine compound; organofluorine compound; quinazolines	antineoplastic agent; tyrosine kinase inhibitor
cimicoxib	[no description available]	low	0	aromatic ether; imidazoles; organochlorine compound; organofluorine compound; sulfonamide	cyclooxygenase 2 inhibitor; non-steroidal anti-inflammatory drug
n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide	[no description available]	low	0	chloroindole; organochlorine compound; sulfonamide	antineoplastic agent; EC 4.2.1.1 (carbonic anhydrase) inhibitor
nsc-89199	[no description available]	low	0	carbamate ester; organochlorine compound; steroid phosphate
estramustine	[no description available]	low	0	17beta-hydroxy steroid; carbamate ester; organochlorine compound	alkylating agent; antineoplastic agent; radiation protective agent
acivicin	[no description available]	low	0	isoxazoles; non-proteinogenic L-alpha-amino acid; organochlorine compound	antileishmanial agent; antimetabolite; antimicrobial agent; antineoplastic agent; EC 2.3.2.2 (gamma-glutamyltransferase) inhibitor; glutamine antagonist; metabolite
o-(chloroacetylcarbamoyl)fumagillol	[no description available]	low	0	carbamate ester; organochlorine compound; semisynthetic derivative; sesquiterpenoid; spiro-epoxide	angiogenesis inhibitor; antineoplastic agent; EC 1.5.1.3 (dihydrofolate reductase) inhibitor; methionine aminopeptidase 2 inhibitor; retinoic acid receptor alpha antagonist
griseofulvin	[no description available]	low	0	1-benzofurans; antibiotic antifungal drug; benzofuran antifungal drug; organochlorine compound; oxaspiro compound	antibacterial agent; Penicillium metabolite
mometasone furoate	[no description available]	low	0	11beta-hydroxy steroid; 2-furoate ester; 20-oxo steroid; 3-oxo-Delta(1),Delta(4)-steroid; organochlorine compound; steroid ester	anti-allergic agent; anti-inflammatory drug
ochratoxin a	[no description available]	low	0	isochromanes; monocarboxylic acid amide; N-acyl-L-phenylalanine; organochlorine compound; phenylalanine derivative	Aspergillus metabolite; calcium channel blocker; carcinogenic agent; mycotoxin; nephrotoxin; Penicillium metabolite; teratogenic agent
chlorpromazine n-oxide	[no description available]	low	0	organochlorine compound; phenothiazines; tertiary amine oxide	metabolite
loteprednol etabonate	[no description available]	low	0	11beta-hydroxy steroid; 3-oxo-Delta(1),Delta(4)-steroid; etabonate ester; organochlorine compound; steroid acid ester; steroid ester	anti-inflammatory drug
melphalan	[no description available]	low	0	L-phenylalanine derivative; nitrogen mustard; non-proteinogenic L-alpha-amino acid; organochlorine compound	alkylating agent; antineoplastic agent; carcinogenic agent; drug allergen; immunosuppressive agent
bromochloroacetic acid	[no description available]	low	0	2-bromocarboxylic acid; monocarboxylic acid; organochlorine compound
tolfenamic acid	[no description available]	low	0	aminobenzoic acid; organochlorine compound; secondary amino compound	EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; EC 2.7.1.33 (pantothenate kinase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug
1,4-dichloro-2-butene	[no description available]	low	0	organochlorine compound
1-(4-chlorophenyl)-1-cyclohexyl-3-(4-morpholinyl)-1-propanol	[no description available]	low	0	organochlorine compound
2-[(3-chlorophenyl)-(3-oxo-5-propyl-1,2-dihydropyrazol-4-yl)methyl]propanedinitrile	[no description available]	low	0	organochlorine compound
1-piperidinecarboxylic acid (5-chloro-8-quinolinyl) ester	[no description available]	low	0	organochlorine compound; quinolines
transfluthrin	[no description available]	low	0	carboxylic ester; cyclopropanes; organochlorine compound; organofluorine compound	pyrethroid ester insecticide
tram 34	[no description available]	low	0	organochlorine compound
N-(2-chlorophenyl)hydrazine-1-carbothioamide	[no description available]	low	0	organochlorine compound
3-pyridinecarboxylic acid (5-chloro-8-quinolinyl) ester	[no description available]	low	0	organochlorine compound; quinolines
CHIC-35	[no description available]	low	0	aromatic compound; organic heterotricyclic compound; organochlorine compound; primary carboxamide	EC 3.5.1.98 (histone deacetylase) inhibitor
dieldrin	[no description available]	low	0	epoxide; organochlorine compound; organochlorine insecticide	carcinogenic agent; xenobiotic
3-(2-chlorophenyl)-5-methyl-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-4-isoxazolecarboxamide	[no description available]	low	0	organochlorine compound
4-chloro-N-(4-chloro-2-methylphenyl)-5-dithiazolimine	[no description available]	low	0	organochlorine compound
1-[(7-chloro-4-quinolinyl)amino]-3-(2,4-dichlorophenyl)thiourea	[no description available]	low	0	organochlorine compound; quinolines
2-chloro-N-[3-[(2-chlorophenyl)methyl]-2-thiazolylidene]acetamide	[no description available]	low	0	organochlorine compound
2-(4-chlorophenyl)guanidine	[no description available]	low	0	organochlorine compound
2-(4-chlorophenyl)-6-(methylthio)-4-oxo-2,3-dihydro-1,3-thiazine-5-carbonitrile	[no description available]	low	0	organochlorine compound
N-(4-chlorophenethyl)-N'-(4-chlorophenyl)urea	[no description available]	low	0	organochlorine compound
6-amino-4-(3-chlorophenyl)-3-methyl-1-(phenylmethyl)-4H-pyrano[2,3-c]pyrazole-5-carbonitrile	[no description available]	low	0	organochlorine compound; pyranopyrazole
5-chloro-7-[3-pyridinyl-(2-pyridinylamino)methyl]-8-quinolinol	[no description available]	low	0	organochlorine compound; quinolines
cb 7969312	[no description available]	low	0	organochlorine compound; quinolines
toremifene	[no description available]	low	0	aromatic ether; organochlorine compound; tertiary amine	antineoplastic agent; bone density conservation agent; estrogen antagonist; estrogen receptor modulator
ospemifene	[no description available]	low	0	aromatic ether; organochlorine compound; primary alcohol	anti-inflammatory agent; antineoplastic agent; estrogen receptor modulator
dasatinib	[no description available]	low	0	1,3-thiazoles; aminopyrimidine; monocarboxylic acid amide; N-(2-hydroxyethyl)piperazine; N-arylpiperazine; organochlorine compound; secondary amino compound; tertiary amino compound	anticoronaviral agent; antineoplastic agent; tyrosine kinase inhibitor
N-[(4-chlorophenyl)methyl]-3-(1-ethyl-5-methyl-4-pyrazolyl)-4,5-dihydroisoxazole-5-carboxamide	[no description available]	low	0	organochlorine compound
4-butyl-3-(4-chloro-1,5-dimethyl-3-pyrazolyl)-1H-1,2,4-triazole-5-thione	[no description available]	low	0	organochlorine compound
quinoxyfen	[no description available]	low	0	aromatic ether; monofluorobenzenes; organochlorine compound; quinolines	antifungal agrochemical
5-chloro-7-[1-piperidinyl(2-pyridinyl)methyl]-8-quinolinol	[no description available]	low	0	organochlorine compound; quinolines
5-chloro-7-[(4-ethyl-1-piperazinyl)-(3-pyridinyl)methyl]-8-quinolinol	[no description available]	low	0	organochlorine compound; quinolines
ML162	[no description available]	low	0	monochlorobenzenes; monomethoxybenzene; organochlorine compound; secondary carboxamide; tertiary carboxamide; thiophenes	EC 1.11.1.9 (glutathione peroxidase) inhibitor; ferroptosis inducer
epi 001	[no description available]	low	0	diether; organochlorine compound	androgen antagonist
3-[(3-chlorophenyl)methylthio]-N-cyclopentylpropanamide	[no description available]	low	0	organochlorine compound
5-[3-(2-chloro-6-methoxy-3-quinolinyl)-5-(2-furanyl)-3,4-dihydropyrazol-2-yl]-5-oxopentanoic acid	[no description available]	low	0	organochlorine compound; quinolines
[3-(2-chloro-6-ethoxy-3-quinolinyl)-5-phenyl-3,4-dihydropyrazol-2-yl]-thiophen-2-ylmethanone	[no description available]	low	0	organochlorine compound; quinolines
4-chloro-N-(1,3,4-thiadiazol-2-yl)-5-dithiazolimine	[no description available]	low	0	organochlorine compound
[4-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl]-(2-oxiranyl)methanone	[no description available]	low	0	organochlorine compound
clodronic acid	[no description available]	low	0	organochlorine compound
ex 527	[no description available]	low	0	carbazoles; monocarboxylic acid amide; organochlorine compound
ro 60-0175	[no description available]	low	0	indoles; organochlorine compound; organofluorine compound; primary amino compound
maytansine	[no description available]	low	0	alpha-amino acid ester; carbamate ester; epoxide; maytansinoid; organic heterotetracyclic compound; organochlorine compound	antimicrobial agent; antimitotic; antineoplastic agent; plant metabolite; tubulin modulator
cyhalothrin	[no description available]	low	0	aromatic ether; cyclopropanecarboxylate ester; nitrile; organochlorine compound; organofluorine compound	agrochemical; pyrethroid ester acaricide; pyrethroid ester insecticide
arachidonyl-2-chloroethylamide	[no description available]	low	0	fatty amide; organochlorine compound; secondary carboxamide; synthetic cannabinoid	CB1 receptor agonist; CB2 receptor agonist; neuroprotective agent
nostocarboline	[no description available]	low	0	alkaloid; beta-carbolines; organic cation; organochlorine compound	antimalarial; EC 3.1.1.8 (cholinesterase) inhibitor; metabolite
su 11652	[no description available]	low	0	olefinic compound; organochlorine compound; oxindoles; pyrrolecarboxamide; tertiary amino compound	EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor
chlorferron	[no description available]	low	0	organochlorine compound
2-amino-6-chloropurine	[no description available]	low	0	2-aminopurines; organochlorine compound
clodinafop	[no description available]	low	0	aromatic ether; monocarboxylic acid; organochlorine compound; organofluorine compound; pyridines	EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor; phenoxy herbicide
salubrinal	[no description available]	low	0	aminal; organochlorine compound; quinolines; secondary carboxamide; thioureas
picloxydine	[no description available]	low	0	organochlorine compound
ma-1	[no description available]	low	0	carboxamidine; organochlorine compound; pyrimidone; pyrrolidines	antineoplastic agent; EC 2.4.2.4 (thymidine phosphorylase) inhibitor
bifenthrin	[no description available]	low	0	carboxylic ester; cyclopropanecarboxylate ester; cyclopropanes; organochlorine compound; organofluorine compound	pyrethroid ester acaricide; pyrethroid ester insecticide
chaetoviridin a	[no description available]	low	0	azaphilone; beta-hydroxy ketone; enone; gamma-lactone; organic heterotricyclic compound; organochlorine compound; secondary alcohol	antifungal agent; Chaetomium metabolite
su 5614	[no description available]	low	0	organochlorine compound; oxindoles; pyrroles	vascular endothelial growth factor receptor antagonist
bay 12-9566	[no description available]	low	0	biphenyls; organochlorine compound
rwj-333369	[no description available]	low	0	organochlorine compound
2-[3-(3-chlorophenyl)-5-isoxazolyl]-1-hydroxy-4H-1,2,4-benzotriazin-3-one	[no description available]	low	0	organochlorine compound
nsc 716970	[no description available]	low	0	aromatic amine; aromatic ether; indolecarboxamide; organochlorine compound	antineoplastic agent
lonafarnib	[no description available]	low	0	benzocycloheptapyridine; heteroarylpiperidine; N-acylpiperidine; organobromine compound; organochlorine compound; ureas
cangrelor	[no description available]	low	0	adenosine 5'-phosphate; aryl sulfide; nucleoside triphosphate analogue; organochlorine compound; organofluorine compound; secondary amino compound	P2Y12 receptor antagonist; platelet aggregation inhibitor
cyazofamid	[no description available]	low	0	imidazole fungicide; imidazoles; nitrile; organochlorine compound; sulfamides; sulfonamide fungicide	antifungal agrochemical; mitochondrial cytochrome-bc1 complex inhibitor
avanafil	[no description available]	low	0	aromatic amide; monocarboxylic acid amide; organochlorine compound; prolinols; pyrimidines	EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; vasodilator agent
rivaroxaban	[no description available]	low	0	aromatic amide; lactam; monocarboxylic acid amide; morpholines; organochlorine compound; oxazolidinone; thiophenes	anticoagulant; EC 3.4.21.6 (coagulation factor Xa) inhibitor
estin	[no description available]	low	0	1-benzofurans; ether; methyl ester; organochlorine compound; oxaspiro compound; phenols	Aspergillus metabolite; Penicillium metabolite
pitolisant	[no description available]	low	0	organochlorine compound
dysidenin	[no description available]	low	0	1,3-thiazoles; organochlorine compound; secondary carboxamide; tertiary carboxamide	animal metabolite; marine metabolite; toxin
6-chlorotryptophan	[no description available]	low	0	L-alpha-amino acid zwitterion; L-tryptophan derivative; non-proteinogenic L-alpha-amino acid; organochlorine compound
tolfenpyrad	[no description available]	low	0	aromatic amide; aromatic ether; organochlorine compound; pyrazole insecticide	agrochemical; antifungal agent; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor; mitochondrial NADH:ubiquinone reductase inhibitor
saracatinib	[no description available]	low	0	aromatic ether; benzodioxoles; diether; N-methylpiperazine; organochlorine compound; oxanes; quinazolines; secondary amino compound	anticoronaviral agent; antineoplastic agent; apoptosis inducer; autophagy inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; radiosensitizing agent
marizomib	[no description available]	low	0	beta-lactone; gamma-lactam; organic heterobicyclic compound; organochlorine compound; salinosporamide	antineoplastic agent; proteasome inhibitor
cyantraniliprole	[no description available]	low	0	nitrile; organobromine compound; organochlorine compound; pyrazole insecticide; pyridines; secondary carboxamide	ryanodine receptor agonist
lorcaserin	[no description available]	low	0	benzazepine; organochlorine compound	anti-obesity agent; appetite depressant
3-(4-chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide	[no description available]	low	0	organochlorine compound
N-[(2-chlorophenyl)methyl]-2-(4-ethyl-1-oxo-2-pyrrolo[1,2-d][1,2,4]triazinyl)acetamide	[no description available]	low	0	organochlorine compound
complestatin	[no description available]	low	0	cyclic ether; heterodetic cyclic peptide; indoles; organic heterobicyclic compound; organochlorine compound; peptide antibiotic; polyphenol	anti-HIV-1 agent; antimicrobial agent; HIV-1 integrase inhibitor; metabolite
neuroprotectin a	[no description available]	low	0	cyclic ether; heterodetic cyclic peptide; indoles; organochlorine compound; polyphenol	HIV-1 integrase inhibitor; metabolite
cnf 2024	[no description available]	low	0	2-aminopurines; aromatic ether; organochlorine compound; pyridines	antineoplastic agent; Hsp90 inhibitor
4'-epichaetoviridin A	[no description available]	low	0	azaphilone; beta-hydroxy ketone; enone; gamma-lactone; organic heterotricyclic compound; organochlorine compound; secondary alcohol	Chaetomium metabolite
plx 4720	[no description available]	low	0	aromatic ketone; difluorobenzene; organochlorine compound; pyrrolopyridine; sulfonamide	antineoplastic agent; B-Raf inhibitor
N-[3-(3-chlorophenyl)phenyl]-1-(3-isoxazolylmethyl)-4-piperidinecarboxamide	[no description available]	low	0	biphenyls; organochlorine compound
N-[3-(3-chlorophenyl)phenyl]-1-(3-oxolanylmethyl)-4-piperidinecarboxamide	[no description available]	low	0	biphenyls; organochlorine compound
marinopyrrole a	[no description available]	low	0	aromatic ketone; organochlorine compound; phenols; pyrroles	antibacterial agent; antimicrobial agent; antineoplastic agent; bacterial metabolite; marine metabolite
suvorexant	[no description available]	low	0	1,3-benzoxazoles; aromatic amide; diazepine; organochlorine compound; triazoles	central nervous system depressant; orexin receptor antagonist
chaetoviridin E	[no description available]	low	0	azaphilone; enone; gamma-lactone; organic heterotricyclic compound; organochlorine compound	Chaetomium metabolite
pexidartinib	[no description available]	low	0	aminopyridine; organochlorine compound; organofluorine compound; pyrrolopyridine; secondary amino compound	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
4-chloro-N-(5-methyl-1,3,4-oxadiazol-2-yl)-5-dithiazolimine	[no description available]	low	0	organochlorine compound
thiopental sodium	[no description available]	low	0	organochlorine compound; piperazines; pyrimidines	antineoplastic agent; tyrosine kinase inhibitor
jq1 compound	[no description available]	low	0	carboxylic ester; organochlorine compound; tert-butyl ester; thienotriazolodiazepine	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; apoptosis inducer; bromodomain-containing protein 4 inhibitor; cardioprotective agent; ferroptosis inducer
N-[9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide	[no description available]	low	0	aromatic amide; bridged compound; olefinic compound; organochlorine compound; organofluorine compound; pyrazoles
lornoxicam	[no description available]	low	0	heteroaryl hydroxy compound; monocarboxylic acid amide; organochlorine compound; pyridines; thienothiazine	antipyretic; non-narcotic analgesic; non-steroidal anti-inflammatory drug
AZD3463	[no description available]	low	0	aminopiperidine; aminopyrimidine; indoles; monomethoxybenzene; organochlorine compound; secondary amino compound; tertiary amino compound	antineoplastic agent; apoptosis inducer; autophagy inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
ceritinib	[no description available]	low	0	aminopyrimidine; aromatic ether; organochlorine compound; piperidines; secondary amino compound; sulfone	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
HG-10-102-01	[no description available]	low	0	aminopyrimidine; aromatic ether; monocarboxylic acid amide; morpholines; organochlorine compound; secondary amino compound	EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
opt 80	[no description available]	low	0	carboxylic ester; glycoside; macrolide antibiotic; organochlorine compound; phenols	antibacterial drug; bacterial metabolite; EC 2.7.7.6 (RNA polymerase) inhibitor
acarbose	[no description available]	low	0	chondramide; indoles; organochlorine compound; phenols	antineoplastic agent; bacterial metabolite
clothianidin	[no description available]	low	0	1,3-thiazoles; 2-nitroguanidine derivative; clothianidin; organochlorine compound	environmental contaminant; neonicotinoid insectide; nicotinic acetylcholine receptor agonist; xenobiotic
THZ531	[no description available]	low	0	aminopyrimidine; enamide; indoles; N-acylpiperidine; organochlorine compound; secondary amino compound; secondary carboxamide	antineoplastic agent; apoptosis inducer; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
clozapine	[no description available]	low	0	benzodiazepine; N-arylpiperazine; N-methylpiperazine; organochlorine compound	adrenergic antagonist; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; environmental contaminant; GABA antagonist; histamine antagonist; muscarinic antagonist; second generation antipsychotic; serotonergic antagonist; xenobiotic
norclozapine	[no description available]	low	0	dibenzodiazepine; organochlorine compound; piperazines	delta-opioid receptor agonist; metabolite; serotonergic antagonist
5-[1-[(2-chlorophenyl)methyl]-2,5-dimethyl-3-pyrrolyl]-N-(1-methoxypropan-2-yl)-6H-1,3,4-thiadiazin-2-amine	[no description available]	low	0	organochlorine compound
XL413	[no description available]	low	0	benzofuropyrimidine; organochlorine compound; pyrrolidines	antineoplastic agent; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
albendazole	[no description available]	low	0	aryl sulfide; benzimidazoles; benzimidazolylcarbamate fungicide; carbamate ester	anthelminthic drug; microtubule-destabilising agent; tubulin modulator
azathioprine	[no description available]	low	0	aryl sulfide; C-nitro compound; imidazoles; thiopurine	antimetabolite; antineoplastic agent; carcinogenic agent; DNA synthesis inhibitor; hepatotoxic agent; immunosuppressive agent; prodrug
bithionol	[no description available]	low	0	aryl sulfide; bridged diphenyl antifungal drug; bridged diphenyl fungicide; dichlorobenzene; organochlorine pesticide; polyphenol	antifungal agrochemical; antiplatyhelmintic drug
fenbendazole	[no description available]	low	0	aryl sulfide; benzimidazoles; carbamate ester	antinematodal drug
methiothepin	[no description available]	low	0	aryl sulfide; dibenzothiepine; N-alkylpiperazine; tertiary amino compound	antipsychotic agent; dopaminergic antagonist; geroprotector; serotonergic antagonist
1-(ethoxymethyl)-5-isopropyl-6-(phenylsulfanyl)uracil	[no description available]	low	0	aryl sulfide; pyrimidone
2,3-bis[amino-[(2-aminophenyl)thio]methylidene]butanedinitrile	[no description available]	low	0	aryl sulfide
fentichlor	[no description available]	low	0	aryl sulfide; bridged diphenyl antifungal drug; monochlorobenzenes; polyphenol	antiinfective agent; drug allergen
methylphenylsulfide	[no description available]	low	0	aryl sulfide; benzenes
diphenyl sulfide	[no description available]	low	0	aryl sulfide
methiocarb	[no description available]	low	0	aryl sulfide; carbamate ester; methyl sulfide	acaricide; agrochemical; avicide; EC 3.1.1.7 (acetylcholinesterase) inhibitor; environmental contaminant; insecticide; molluscicide; xenobiotic
pipazethate	[no description available]	low	0	aryl sulfide
butoconazole nitrate	[no description available]	low	0	aryl sulfide; conazole antifungal drug; imidazole antifungal drug; imidazoles; organic nitrate salt
butoconazole	[no description available]	low	0	aryl sulfide; conazole antifungal drug; dichlorobenzene; imidazole antifungal drug; imidazoles; monochlorobenzenes
fenticonazole	[no description available]	low	0	aryl sulfide; dichlorobenzene; ether; imidazoles
nelfinavir	[no description available]	low	0	aryl sulfide; benzamides; organic heterobicyclic compound; phenols; secondary alcohol; tertiary amino compound	antineoplastic agent; HIV protease inhibitor
1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine	[no description available]	low	0	aryl sulfide; primary alcohol; pyrimidone	antiviral drug; HIV-1 reverse transcriptase inhibitor
anpirtoline	[no description available]	low	0	aryl sulfide
azintamid	[no description available]	low	0	aryl sulfide
tiazuril	[no description available]	low	0	aryl sulfide
g 25671	[no description available]	low	0	aryl sulfide
irgarol 1051	[no description available]	low	0	aryl sulfide; cyclopropanes; diamino-1,3,5-triazine	antifouling biocide; environmental contaminant; xenobiotic
zofenopril	[no description available]	low	0	aryl sulfide; L-proline derivative; N-acyl-L-amino acid; thioester	anticonvulsant; apoptosis inhibitor; cardioprotective agent; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor; prodrug; vasodilator agent
bnps-skatole	[no description available]	low	0	aryl sulfide; bromoindole; C-nitro compound	reagent
5-(Ethylthio)-1,3,4-thiadiazol-2-amine	[no description available]	low	0	aryl sulfide
2-(s-glutathionyl)hydroquinone	[no description available]	low	0	aryl sulfide; glutathione conjugate; hydroquinones	human xenobiotic metabolite; nephrotoxic agent
2-s-cysteinyldopa	[no description available]	low	0	amino dicarboxylic acid; aryl sulfide; catechols; diamine; L-tyrosine derivative; S-conjugate; S-organyl-L-cysteine	human urinary metabolite
2-methyl-3-(phenylthio)pyrazine	[no description available]	low	0	aryl sulfide
3-(prop-2-enylthio)-5-thiophen-2-yl-1H-1,2,4-triazole	[no description available]	low	0	aryl sulfide
5-[(4-chlorophenyl)methylthio]-1,3,4-thiadiazol-2-amine	[no description available]	low	0	aryl sulfide
pd 173955	[no description available]	low	0	aryl sulfide; dichlorobenzene; methyl sulfide; pyridopyrimidine	tyrosine kinase inhibitor
6-methyl-2-(methylthio)-N-phenyl-5-prop-2-enyl-4-pyrimidinamine	[no description available]	low	0	aryl sulfide
4-(2-pyridinylthio)benzofuro[3,2-d]pyrimidine	[no description available]	low	0	aryl sulfide
2-[[3-cyano-6-(2-furanyl)-4-(trifluoromethyl)-2-pyridinyl]thio]propanoic acid ethyl ester	[no description available]	low	0	aryl sulfide
N,N-di(propan-2-yl)-2-[(1-propyl-5-tetrazolyl)thio]acetamide	[no description available]	low	0	aryl sulfide
3-[(4,6-dimethyl-2-pyrimidinyl)thio]-N,N-dimethylpropanamide	[no description available]	low	0	aryl sulfide
2-[(2,5-dimethylphenyl)methylthio]-5-(3-pyridinyl)-1,3,4-oxadiazole	[no description available]	low	0	aryl sulfide
2-[[5-(2-furanyl)-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]thio]-1-(4-morpholinyl)ethanone	[no description available]	low	0	aryl sulfide
N,N-diethyl-2-[(3-thiophen-2-yl-7-isothiazolo[4,5-d]pyrimidinyl)thio]acetamide	[no description available]	low	0	aryl sulfide
2-[[3-cyano-6-cyclopropyl-4-(trifluoromethyl)-2-pyridinyl]thio]acetic acid methyl ester	[no description available]	low	0	aryl sulfide
4-[(3-cyano-4,6-dimethyl-2-pyridinyl)thio]-3-oxobutanoic acid propan-2-yl ester	[no description available]	low	0	aryl sulfide; isopropyl ester
2-[[5-[[2-(3-chloroanilino)-4-thiazolyl]methyl]-4-(3-methoxypropyl)-1,2,4-triazol-3-yl]thio]acetic acid methyl ester	[no description available]	low	0	aryl sulfide
2-[(6-amino-3,5-dicyano-4-thiophen-2-yl-2-pyridinyl)thio]-N-(2-phenylethyl)acetamide	[no description available]	low	0	aryl sulfide
6-tert-butyl-3-cyclohexyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine	[no description available]	low	0	aryl sulfide
2-[(3-cyano-6-cyclopropyl-4-thiophen-2-yl-2-pyridinyl)thio]acetamide	[no description available]	low	0	aryl sulfide
5-[2-[(4-chlorophenyl)thio]-1-oxoethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid methyl ester	[no description available]	low	0	aryl sulfide
4-(benzylsulfanyl)thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; benzenes; thienopyrimidine
2-(Phenylthio)nicotinic acid	[no description available]	low	0	aryl sulfide
5-[(2-Chloro-6-fluorobenzyl)thio]-1,3,4-thiadiazol-2-amine	[no description available]	low	0	aryl sulfide
2-[(2-fluorophenyl)methylthio]-5-(4-methylphenyl)-1,3,4-oxadiazole	[no description available]	low	0	aryl sulfide
2-[(4-fluorophenyl)methylthio]-5-(2-methylphenyl)-1,3,4-oxadiazole	[no description available]	low	0	aryl sulfide
2-[(6-amino-3,5-dicyano-2-pyridinyl)thio]acetic acid ethyl ester	[no description available]	low	0	aryl sulfide
2-methyl-5-[(2-methyl-4-quinolinyl)thio]-1,3,4-thiadiazole	[no description available]	low	0	aryl sulfide
2-[(4-bromophenyl)methylthio]-5-(3-pyridinyl)-1,3,4-oxadiazole	[no description available]	low	0	aryl sulfide
GS4012 free base	[no description available]	low	0	aryl sulfide; monomethoxybenzene; pyridines	VEGF activator
2-(phenylmethylthio)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole	[no description available]	low	0	aryl sulfide
3-(2-methylpropylthio)-1H-1,2,4-triazol-5-amine	[no description available]	low	0	aryl sulfide
8-[(2-methyl-5-nitro-1,2,4-triazol-3-yl)thio]quinoline	[no description available]	low	0	aryl sulfide
2-[(3-fluorophenyl)methylthio]pyrimidine-4,6-diamine	[no description available]	low	0	aryl sulfide
2-(4-chlorophenyl)-4-(ethylthio)-6-(1-pyrrolidinyl)pyrimidine	[no description available]	low	0	aryl sulfide
2-[(2-chlorophenyl)methylthio]-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole	[no description available]	low	0	aryl sulfide
N-[(2-methylphenyl)methyl]-2-[(4-methylphenyl)thio]acetamide	[no description available]	low	0	aryl sulfide
N,N-dimethyl-3-[(4-methylphenyl)thio]propanamide	[no description available]	low	0	aryl sulfide
3-[(2-chloro-6-fluorophenyl)methylthio]-4-ethyl-5-(2-furanyl)-1,2,4-triazole	[no description available]	low	0	aryl sulfide
3-cyclohexyl-5-(phenylmethylthio)-1,2,4-triazol-4-amine	[no description available]	low	0	aryl sulfide
N,N-dimethyl-2-[(2-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)thio]ethanamine	[no description available]	low	0	aryl sulfide
3-chloro-4-[(1-ethyl-2-benzimidazolyl)thio]aniline	[no description available]	low	0	aryl sulfide
2-[[3-cyano-6-(2-furanyl)-4-(trifluoromethyl)-2-pyridinyl]thio]-N,N-diethylacetamide	[no description available]	low	0	aryl sulfide
5-[2-[(4-chlorophenyl)thio]-1-oxoethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid ethyl ester	[no description available]	low	0	aryl sulfide
2-[(4-chlorophenyl)thio]-N-(5-oxo-1-phenyl-4H-pyrazol-3-yl)acetamide	[no description available]	low	0	aryl sulfide
N-[3-(1,3-benzothiazol-2-ylthio)-4-hydroxyphenyl]-4-chlorobenzenesulfonamide	[no description available]	low	0	aryl sulfide
3-[5-[(4-chlorophenyl)methylthio]-1,3,4-oxadiazol-2-yl]-1-(phenylmethyl)-2-pyridinone	[no description available]	low	0	aryl sulfide
4-[(3-methylphenyl)thio]-2-phenyl-5-pyrimidinecarboxylic acid	[no description available]	low	0	aryl sulfide
3-phenyl-5-[(phenylthio)methyl]isoxazole	[no description available]	low	0	aryl sulfide
3-(4-chlorophenyl)-5-[(phenylthio)methyl]isoxazole	[no description available]	low	0	aryl sulfide
3-[4-ethyl-5-[(4-methylphenyl)methylthio]-1,2,4-triazol-3-yl]-1-phenyl-4-pyridazinone	[no description available]	low	0	aryl sulfide
5-[3-[(4-methylphenyl)methoxy]-2-thiophenyl]-3-(methylthio)-1H-1,2,4-triazole	[no description available]	low	0	aryl sulfide
5-methoxy-4-[(2-methoxyphenyl)thio]-2-phenylpyrimidine	[no description available]	low	0	aryl sulfide
3-[(4-ethylsulfonyl-2-nitrophenyl)thio]-4-methyl-1,2,4-triazole	[no description available]	low	0	aryl sulfide
1-[[1-oxo-2-[[5-(phenylmethylthio)-1,3,4-thiadiazol-2-yl]thio]ethyl]amino]-3-phenylthiourea	[no description available]	low	0	aryl sulfide
8-(dimethylamino)-3,4-dihydro-2H-pyrimido[2,1-b][1,3]thiazin-6-one	[no description available]	low	0	aryl sulfide
1-[[4-[(3,4-dichlorophenyl)thio]-3-pyridinyl]sulfonyl]-3-propylurea	[no description available]	low	0	aryl sulfide
N,N-dimethyl-3-[(2-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)thio]-1-propanamine	[no description available]	low	0	aryl sulfide
2-tert-butyl-4-[(4-chlorophenyl)thio]-5-methyl-1H-pyrazol-3-one	[no description available]	low	0	aryl sulfide
benzoic acid [2-oxo-2-[2-(phenylthio)anilino]ethyl] ester	[no description available]	low	0	aryl sulfide
7-[[[5-(2,4-dimethylanilino)-1,3,4-thiadiazol-2-yl]thio]methyl]-5-thiazolo[3,2-a]pyrimidinone	[no description available]	low	0	aryl sulfide
N-phenyl-5-(propan-2-ylthio)-1,3,4-thiadiazol-2-amine	[no description available]	low	0	aryl sulfide
2-[(6-amino-3,5-dicyano-4-thiophen-2-yl-2-pyridinyl)thio]acetic acid ethyl ester	[no description available]	low	0	aryl sulfide
5-methyl-3-[3-[(5-methyl-1H-1,2,4-triazol-3-yl)thio]propylthio]-1H-1,2,4-triazole	[no description available]	low	0	aryl sulfide
N-[2-[(2-methylphenyl)methylthio]ethyl]-3-[(4-methylphenyl)thio]propanamide	[no description available]	low	0	aryl sulfide
1,3-dimethyl-5-[[5-(phenylthio)-2-furanyl]methylidene]-1,3-diazinane-2,4,6-trione	[no description available]	low	0	aryl sulfide
2-(1,3-benzothiazol-2-yl)-4-[(4-fluorophenyl)thio]-5-methyl-3-pyrazolamine	[no description available]	low	0	aryl sulfide
2-(4,6-dimethyl-2-pyrimidinyl)-4-[(4-fluorophenyl)thio]-5-methyl-3-pyrazolamine	[no description available]	low	0	aryl sulfide
2-[[5-(2-fluoroanilino)-1,3,4-thiadiazol-2-yl]thio]-N-(2-furanylmethyl)acetamide	[no description available]	low	0	aryl sulfide
1-(2-furanyl)-2-(1H-1,2,4-triazol-5-ylthio)ethanone	[no description available]	low	0	aryl sulfide
4-[(1-methyl-5-tetrazolyl)thio]-5-phenylthieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
2-chloro-N-[4-[(3,4-dimethylphenyl)thio]phenyl]acetamide	[no description available]	low	0	aryl sulfide
2-[(3,4-dimethylphenyl)thio]-3-pyridinecarboxylic acid	[no description available]	low	0	aryl sulfide
N-[6-amino-2,4-dioxo-1-(phenylmethyl)-5-pyrimidinyl]-2-[(5-amino-1,3,4-thiadiazol-2-yl)thio]-N-methylacetamide	[no description available]	low	0	aryl sulfide
2-[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]-1-(1H-pyrrol-2-yl)ethanone	[no description available]	low	0	aryl sulfide
N-tert-butyl-2-[[4-(4-fluorophenyl)-2-thiazolyl]thio]acetamide	[no description available]	low	0	aryl sulfide
2-(4-chlorophenyl)-5-[[(4-methyl-2-thiazolyl)thio]methyl]-1,3,4-oxadiazole	[no description available]	low	0	aryl sulfide
s-phenyl-n-acetylcysteine	[no description available]	low	0	aryl sulfide; S-substituted N-acetyl-L-cysteine	biomarker; human urinary metabolite
4-amino-2-(4-chlorophenyl)-6-(methylthio)pyrimidine-5-carbonitrile	[no description available]	low	0	aryl sulfide
[3,5-Bis(methylsulfanyl)-4-isothiazolyl]methanol	[no description available]	low	0	aryl sulfide
bi-78d3	[no description available]	low	0	aryl sulfide
2-[(4-chlorophenyl)thio]-1-methyl-3-indolecarboxaldehyde	[no description available]	low	0	aryl sulfide
1-[(3-chlorophenyl)methyl]-3-[5-(methylthio)-1,3,4-oxadiazol-2-yl]-2-pyridinone	[no description available]	low	0	aryl sulfide
2-[(2-methylphenyl)methylthio]-5-pyridin-4-yl-1,3,4-oxadiazole	[no description available]	low	0	aryl sulfide
3-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)thio]propanoic acid ethyl ester	[no description available]	low	0	aryl sulfide
2-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)thio]butanedioic acid	[no description available]	low	0	aryl sulfide
N-{2-[(4-amino-5-cyano-2-pyrimidinyl)sulfanyl]acetyl}-N'-phenylurea	[no description available]	low	0	aryl sulfide
2-[5-[(3-chlorophenyl)thio]-2-thiophenyl]pyridine	[no description available]	low	0	aryl sulfide
2-{5-[2-(Phenylthio)acetyl]-2-thienyl}acetic acid	[no description available]	low	0	aryl sulfide
2-[5-[2-[(4-methylphenyl)thio]-1-oxoethyl]-2-thiophenyl]acetic acid	[no description available]	low	0	aryl sulfide
2-[[2-methyl-5-nitro-3-(phenylmethyl)-4-imidazolyl]thio]-6-nitro-1H-benzimidazole	[no description available]	low	0	aryl sulfide
1-(2-furanyl)-3-(phenylthio)-3-thiophen-2-yl-1-propanone	[no description available]	low	0	aryl sulfide
1-(2-furanyl)-2-[(1-methyl-5-tetrazolyl)thio]ethanone	[no description available]	low	0	aryl sulfide
N-(1-adamantyl)-2-[(1-methyl-2-imidazolyl)thio]acetamide	[no description available]	low	0	aryl sulfide
zofenoprilate	[no description available]	low	0	aryl sulfide; L-proline derivative; N-acyl-L-amino acid; thiol	anticonvulsant; apoptosis inhibitor; cardioprotective agent; drug metabolite; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor; vasodilator agent
vx-745	[no description available]	low	0	aryl sulfide; dichlorobenzene; difluorobenzene; pyrimidopyridazine	anti-inflammatory drug; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
N-methyl-2-[[3-[2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide	[no description available]	low	0	aryl sulfide
2,2-dimethyl-N-[2,2,2-trichloro-1-(2-pyrimidinylthio)ethyl]propanamide	[no description available]	low	0	aryl sulfide
5-methyl-4-[(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)-[4-(methylthio)phenyl]methyl]-1,2-dihydropyrazol-3-one	[no description available]	low	0	aryl sulfide
1-(4-amino-1,2,5-oxadiazol-3-yl)-5-[(2-pyridinylthio)methyl]-4-triazolecarboxylic acid propan-2-yl ester	[no description available]	low	0	aryl sulfide; azole; isopropyl ester; oxadiazole; pyridines
2-[[4-cyano-3-[(2-methoxy-2-oxoethyl)thio]-5-isothiazolyl]thio]acetic acid ethenyl ester	[no description available]	low	0	aryl sulfide
2-[(5-anilino-1,3,4-thiadiazol-2-yl)thio]ethanol	[no description available]	low	0	aryl sulfide
2-amino-4-[5-methyl-2-(methylthio)-3-thiophenyl]-5-oxo-1-(3-pyridinyl)-4,6,7,8-tetrahydroquinoline-3-carbonitrile	[no description available]	low	0	aryl sulfide
3-nitro-4-[[4-(2-oxolanylmethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]thio]benzamide	[no description available]	low	0	aryl sulfide
1-(4-methoxyphenyl)-4-[(4-methylphenyl)thio]-6-oxo-3-pyridazinecarboxylic acid methyl ester	[no description available]	low	0	aryl sulfide
3-(phenylthio)-1-(1-pyrrolidinyl)-1-propanone	[no description available]	low	0	aryl sulfide
gw 7647	[no description available]	low	0	aryl sulfide; monocarboxylic acid; ureas	PPARalpha agonist
2-[(4-methyl-5-sulfanylidene-1,3,4-thiadiazol-2-yl)thio]acetic acid ethyl ester	[no description available]	low	0	aryl sulfide
4-[[7-methyl-4-(phenylthio)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]methyl]morpholine	[no description available]	low	0	aryl sulfide
2-[[4-(4-chlorophenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]thio]-N-(1,1-dioxo-3-thiolanyl)-N-(2-methylpropyl)acetamide	[no description available]	low	0	aryl sulfide
l 663536	[no description available]	low	0	aryl sulfide; indoles; monocarboxylic acid; monochlorobenzenes	antineoplastic agent; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; leukotriene antagonist
2-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)thio]propanoic acid methyl ester	[no description available]	low	0	aryl sulfide
4-[(3-cyano-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio]-3-oxobutanoic acid ethyl ester	[no description available]	low	0	aryl sulfide
5-[[(4-chlorophenyl)thio]methyl]-2-methyl-1H-pyrazol-3-one	[no description available]	low	0	aryl sulfide
1-(1-azepanyl)-2-[(5-methyl-4-nitro-1H-pyrazol-3-yl)thio]ethanone	[no description available]	low	0	aryl sulfide
1-(1-adamantyl)-2-[(1-oxido-2-pyridin-1-iumyl)thio]ethanone	[no description available]	low	0	aryl sulfide
2-[(2-nitro-3-pyridinyl)oxy]-N-[2-(phenylthio)phenyl]acetamide	[no description available]	low	0	aryl sulfide
3-amino-4-[(4-chlorophenyl)thio]benzoic acid methyl ester	[no description available]	low	0	aryl sulfide
5-[(3-nitro-2-pyridinyl)thio]-N-prop-2-enyl-1,3,4-thiadiazol-2-amine	[no description available]	low	0	aryl sulfide
3-(prop-2-enylthio)-[1,2,4]triazino[5,6-d][3,1]benzoxazepine	[no description available]	low	0	aryl sulfide
sulindac sulfide	[no description available]	low	0	aryl sulfide; monocarboxylic acid; organofluorine compound	antineoplastic agent; apoptosis inducer; non-steroidal anti-inflammatory drug
5-[(2-chlorophenyl)thio]-3-(4-methylphenyl)-1,2,4-triazine-6-carboxylic acid ethyl ester	[no description available]	low	0	aryl sulfide
3-(2-oxolanylmethylthio)-5,6-diphenyl-1,2,4-triazine	[no description available]	low	0	aryl sulfide
axitinib	[no description available]	low	0	aryl sulfide; benzamides; indazoles; pyridines	antineoplastic agent; tyrosine kinase inhibitor; vascular endothelial growth factor receptor antagonist
2-[[4-methyl-5-(2-phenylethyl)-1,2,4-triazol-3-yl]thio]acetic acid methyl ester	[no description available]	low	0	aryl sulfide
2-[(3-iodophenyl)methylthio]-5-pyridin-4-yl-1,3,4-oxadiazole	[no description available]	low	0	aryl sulfide
n,n'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine	[no description available]	low	0	aryl sulfide
7-[(4-chlorophenyl)methylthio]-3-methyl-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one	[no description available]	low	0	aryl sulfide
7-[(3-chlorophenyl)methylthio]-3-methyl-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one	[no description available]	low	0	aryl sulfide
3-methyl-7-[(3-methylphenyl)methylthio]-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one	[no description available]	low	0	aryl sulfide
3-(ethylthio)-6-(2-furanyl)pyridazine	[no description available]	low	0	aryl sulfide
3-[(3-fluorophenyl)methylthio]-6-(2-furanyl)pyridazine	[no description available]	low	0	aryl sulfide
3-[(4-bromophenyl)methylthio]-6-(2-furanyl)pyridazine	[no description available]	low	0	aryl sulfide
3-[(4-chlorophenyl)methylthio]-6-(2-furanyl)pyridazine	[no description available]	low	0	aryl sulfide
5-(4-chlorophenyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
gw 501516	[no description available]	low	0	1,3-thiazoles; aromatic ether; aryl sulfide; monocarboxylic acid; organofluorine compound	carcinogenic agent; PPARbeta/delta agonist
4-[(4-methylphenyl)thio]-2-thieno[2,3-c]pyridinecarboxamide	[no description available]	low	0	aryl sulfide
[2-[[2-[(dimethylamino)methyl]phenyl]thio]-5-iodophenyl]methanol	[no description available]	low	0	aryl sulfide
ticagrelor	[no description available]	low	0	aryl sulfide; hydroxyether; organofluorine compound; secondary amino compound; triazolopyrimidines	P2Y12 receptor antagonist; platelet aggregation inhibitor
vortioxetine	[no description available]	low	0	aryl sulfide; N-arylpiperazine	antidepressant; anxiolytic drug; serotonergic agonist; serotonergic antagonist
n,n-dimethyl-2-(2-amino-4-fluorophenylthio)benzylamine	[no description available]	low	0	aryl sulfide
abt-737	[no description available]	low	0	aromatic amine; aryl sulfide; biphenyls; C-nitro compound; monochlorobenzenes; N-arylpiperazine; N-sulfonylcarboxamide; secondary amino compound; tertiary amino compound	anti-allergic agent; anti-inflammatory agent; antineoplastic agent; apoptosis inducer; B-cell lymphoma 2 inhibitor
bay 60-6583	[no description available]	low	0	aminopyridine; aromatic ether; aryl sulfide; cyanopyridine; cyclopropanes; monocarboxylic acid amide	adenosine A2B receptor agonist; anti-inflammatory agent; cardioprotective agent
3-[(3-methylphenyl)methylthio]-6-thiophen-2-ylpyridazine	[no description available]	low	0	aryl sulfide
3-[[5-(4-ethylanilino)-1,3,4-thiadiazol-2-yl]thio]-2-oxolanone	[no description available]	low	0	aryl sulfide
3-(3-pyridinylmethylthio)-6-thiophen-2-ylpyridazine	[no description available]	low	0	aryl sulfide
sgx 523	[no description available]	low	0	aryl sulfide; biaryl; pyrazoles; quinolines; triazolopyridazine	c-Met tyrosine kinase inhibitor; nephrotoxic agent
navitoclax	[no description available]	low	0	aryl sulfide; monochlorobenzenes; morpholines; N-sulfonylcarboxamide; organofluorine compound; piperazines; secondary amino compound; sulfone; tertiary amino compound	antineoplastic agent; apoptosis inducer; B-cell lymphoma 2 inhibitor
5-(4-methoxyphenyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
5-(4-bromophenyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
5-(2-methoxyphenyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
5-(3-methoxyphenyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
5-(3-fluorophenyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
4-[(1-methyl-5-tetrazolyl)thio]-5-[2-(trifluoromethyl)phenyl]thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
4-[(1-methyl-5-tetrazolyl)thio]-5-[3-(trifluoromethyl)phenyl]thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
4-[(1-methyl-5-tetrazolyl)thio]-5-[4-(trifluoromethyl)phenyl]thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
5-(2-bromophenyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
5-(3-bromophenyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
5-(2-chlorophenyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
4-[4-[(1-methyl-5-tetrazolyl)thio]-5-thieno[2,3-d]pyrimidinyl]benzonitrile	[no description available]	low	0	aryl sulfide; thienopyrimidine
4-[(1-methyl-5-tetrazolyl)thio]-5-(4-nitrophenyl)thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
5-(1,3-benzodioxol-5-yl)-4-(1-methyltetrazol-5-yl)sulfanylthieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
4-[(1-methyl-5-tetrazolyl)thio]-5-(3-thiophenyl)thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
5-(2-benzofuranyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
4-[(1-methyl-5-tetrazolyl)thio]-5-(1H-pyrrol-2-yl)thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
5-(3-methylsulfonylphenyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
4-[(1-methyl-5-tetrazolyl)thio]-5-(1-naphthalenyl)thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
5-bromo-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine	[no description available]	low	0	aryl sulfide; thienopyrimidine
monepantel	[no description available]	low	0	(trifluoromethyl)benzenes; aromatic ether; aryl sulfide; nitrile; secondary carboxamide	anthelminthic drug; nematicide
lesinurad	[no description available]	low	0	aryl sulfide; cyclopropanes; monocarboxylic acid; naphthalenes; organobromine compound; triazoles	uricosuric drug
2-(methylthio)-6-(phenylmethyl)-1H-pyrimidin-4-one	[no description available]	low	0	aryl sulfide
2-[(4-chlorophenyl)methylthio]-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-one	[no description available]	low	0	aryl sulfide
2-[[2-[1-(2-methoxyethyl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl]thio]-6-propyl-1H-pyrimidin-4-one	[no description available]	low	0	aryl sulfide
5-methyl-2-methylsulfanyl-6-propyl-1H-pyrimidin-4-one	[no description available]	low	0	aryl sulfide
febantel	[no description available]	low	0	aryl sulfide
2-(butylthio)-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-one	[no description available]	low	0	aryl sulfide
2-(2-phenylethylthio)-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-one	[no description available]	low	0	aryl sulfide

Article	Year
Neuroprotective role of prostaglandin PGE2 EP2 receptor in hemin-mediated toxicity. Neurotoxicology, Volume: 46	2015
Aminoglycoside toxicity: pH dependent inhibition of ADH response. Research communications in chemical pathology and pharmacology, Volume: 52, Issue: 2	1986
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Article	Year
Corticotropin-releasing factor in the basolateral amygdala enhances memory consolidation via an interaction with the beta-adrenoceptor-cAMP pathway: dependence on glucocorticoid receptor activation. The Journal of neuroscience : the official journal of the Society for Neuroscience, Jun-25, Volume: 28, Issue: 26	2008
Lordosis facilitation by LHRH, PGE2 or db-cAMP requires activation of the kinase A signaling pathway in estrogen primed rats. Pharmacology, biochemistry, and behavior, Volume: 86, Issue: 1	2007
Deletion of phenylalanine 508 causes attenuated phosphorylation-dependent activation of CFTR chloride channels. The Journal of physiology, May-01, Volume: 524 Pt 3	2000
Barrier function of porcine choroid plexus epithelial cells is modulated by cAMP-dependent pathways in vitro. Brain research, Jan-17, Volume: 853, Issue: 1	2000
Two phosphatase sites on the Ca2+ channel affecting different kinetic functions. The Journal of physiology, Volume: 470	1993
Regulation of CFTR Cl- conductance in secretion by cellular energy levels. The American journal of physiology, Volume: 264, Issue: 4 Pt 1	1993
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Article	Year
[In vitro study of the effects of arsenic trioxide combined with 8-CPT-cAMP on differentiation induction in retinoic acid resistant acute promyelocytic leukemia cells]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, Volume: 24, Issue: 1	2003
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

8-((4-chlorophenyl)thio)cyclic-3',5'-amp

Description

Cross-References

Synonyms (28)

Roles (1)

Drug Classes (4)

Protein Targets (4)

Inhibition Measurements

Biological Processes (30)

Molecular Functions (15)

Ceullar Components (19)

Bioassays (9)

Research

Studies (560)

Study Types

Research Highlights

Safety/Toxicity (2)

Dosage (6)

Interactions (1)

Condition	Relationship Strength	Studies
Acidosis	low	2
Acute Myelogenous Leukemia	low	2
Acute Myeloid Leukemia	low	2
Acute Myeloid Leukemia with Maturation	low	2
Acute Myeloid Leukemia without Maturation	low	2
Acute Necrotizing Encephalitis, Herpetic	low	1
Acute Promyelocytic Leukemia	low	7
Adenocarcinoma	low	2
Adenocarcinoma, Basal Cell	low	2
Adenocarcinoma, Granular Cell	low	2
Adenocarcinoma, Oxyphilic	low	2
Adenocarcinoma, Tubular	low	2
Adenoma, Malignant	low	2
Adenoma, Prolactin-Secreting, Pituitary	low	1
Adrenal Cancer	low	3
Adrenal Gland Cancer	low	3
Adrenal Gland Neoplasms	low	3
Adrenal Neoplasm	low	3
Adult Spinal Muscular Atrophy	low	1
Adult-Onset Spinal Muscular Atrophy	low	1
Aging	low	4
AIDS, Murine	low	1
Aldosteronism	low	1
Allodynia	low	3
Allodynia, Mechanical	low	3
Allodynia, Tactile	low	3
Allodynia, Thermal	low	3
Alloxan Diabetes	low	3
AML M3	low	7
Amyotrophy, Neurogenic Scapuloperoneal, New England Type	low	1
ANLL	low	2
Arteriosclerosis	low	1
Aura	low	1
Awakening Epilepsy	low	1
Benign Neoplasms, Brain	low	1
Blood Pressure, High	low	3
Brain Cancer	low	1
Brain Metastases	low	1
Brain Neoplasm, Primary	low	1
Brain Neoplasms	low	1
Brain Neoplasms, Benign	low	1
Brain Neoplasms, Malignant	low	1
Brain Neoplasms, Malignant, Primary	low	1
Brain Neoplasms, Primary Malignant	low	1
Brain Tumor, Primary	low	1
Brain Tumor, Recurrent	low	1
Brain Tumors	low	1
Breast Cancer	low	1
Breast Carcinoma	low	1
Breast Neoplasms	low	1
Breast Tumors	low	1
Bulbospinal Neuronopathy	low	1
Cafe-au-Lait Spots with Pulmonic Stenosis	low	1
Cancer of Brain	low	1
Cancer of Breast	low	1
Cancer of Colon	low	2
Cancer of Endometrium	low	1
Cancer of Liver	low	3
Cancer of Pituitary	low	5
Cancer of Prostate	low	3
Cancer of Stomach	low	1
Cancer of the Adrenal Gland	low	3
Cancer of the Brain	low	1
Cancer of the Breast	low	1
Cancer of the Colon	low	2
Cancer of the Endometrium	low	1
Cancer of the Liver	low	3
Cancer of the Pituitary	low	5
Cancer of the Prostate	low	3
Cancer of the Stomach	low	1
Cancer of the Uterus	low	1
Cancer of Uterus	low	1
Cancer, Hepatocellular	low	3
Carcinoma	low	1
Carcinoma of Endometrium	low	1
Carcinoma, Anaplastic	low	1
Carcinoma, Cribriform	low	2
Carcinoma, Granular Cell	low	2
Carcinoma, Hepatocellular	low	2
Carcinoma, Spindle-Cell	low	1
Carcinoma, Tubular	low	2
Carcinoma, Undifferentiated	low	1
Carcinomatosis	low	1
Cardiac Failure	low	1
Cardiac Hypertrophy	low	3
Cardiomegaly	low	3
Cell Transformation, Neoplastic	low	2
Cell Transformation, Viral	low	2
Central Nervous System Disease	low	1
Central Nervous System Diseases	low	1
Central Nervous System Disorder	low	1
Central Nervous System Disorders	low	1
Centrala nervsystemets sjukdomar@sv	low	1
Choline Deficiency	low	1
Choriocarcinoma	low	2
Choroby OUN@pl	low	1
Chromosomal Translocation	low	1
Chromosome Deletion	low	1
CNS Disease	low	1
CNS Diseases	low	1
Colon Cancer	low	2
Colon Neoplasms	low	2
Colonic Cancer	low	2
Colonic Neoplasms	low	2
Common Variable Hypogammaglobulinemia	low	1
Common Variable Immune Deficiency	low	1
Common Variable Immunodeficiency	low	1
Congestive Heart Failure	low	1
Conn Syndrome	low	1
Conn's Syndrome	low	1
Cranial Nerve II Injuries	low	1
Cystic Fibrosis	low	16
Cystic Fibrosis of Pancreas	low	16
Decerebrate Posturing	low	1
Decerebrate State	low	1
Decorticate Rigidity	low	1
Decorticate State	low	1
Deficiency, Choline	low	1
Diabetes Mellitus	low	1
Diabetes Mellitus, Experimental	low	3
Disease Models, Animal	low	5
Distal Spinal Muscular Atrophy	low	1
Doenu00E7as do Sistema Nervoso Central@pt	low	1
Drug Withdrawal Symptoms	low	1
Electrocardiogram QT Prolonged	low	1
Electrolytes	low	1
Encephalitis, Herpes Simplex	low	1
Endometrial Cancer	low	1
Endometrial Carcinoma	low	1
Endometrial Neoplasms	low	1
Endometrium Cancer	low	1
Enfermedades del Sistema Nervioso Central@es	low	1
Enlarged Heart	low	3
Epilepsy	low	1
Epilepsy, Cryptogenic	low	1
Epithelial Neoplasms, Malignant	low	1
Epithelial Tumors, Malignant	low	1
Epithelioma	low	1
Experimental Diabetes Mellitus	low	3
Experimental Hepatoma	low	14
Experimental Hepatomas	low	14
Experimental Liver Neoplasms	low	14
Experimental Lung Inflammation	low	1
Fibrocystic Disease of Pancreas	low	16
Gastric Cancer	low	1
Gastric Cancer, Familial Diffuse	low	1
Gastric Neoplasms	low	1
Glial Cell Tumors	low	5
Glioma	low	5
Heart Decompensation	low	1
Heart Enlargement	low	3
Heart Failure	low	1
Heart Failure, Congestive	low	1
Heart Failure, Left-Sided	low	1
Heart Failure, Right-Sided	low	1
Heart Hypertrophy	low	3
Hepatic Cancer	low	3
Hepatic Neoplasms	low	3
Hepatocellular Cancer	low	3
Hepatocellular Carcinoma	low	2
Hepatoma	low	2
Hepatoma, Experimental	low	14
Hepatoma, Morris	low	14
Hepatoma, Novikoff	low	14
Hepatomas, Experimental	low	14
Hereditary Motor Neuronopathy	low	1
Herpes Encephalitis	low	1
Herpes Simplex Encephalitis	low	1
Herpes Simplex Meningoencephalitis	low	1
Herpetic Acute Necrotizing Encephalitis	low	1
Herpetic Encephalitis	low	1
Herpetic Meningoencephalitis	low	1
Human Mammary Carcinoma	low	1
Hyperaldosteronism	low	1
Hyperalgesia	low	3
Hyperalgesia, Mechanical	low	3
Hyperalgesia, Primary	low	3
Hyperalgesia, Secondary	low	3
Hyperalgesia, Tactile	low	3
Hyperalgesia, Thermal	low	3
Hyperalgesic Sensations	low	3
Hyperalgia	low	3
Hyperalgia, Mechanical	low	3
Hyperalgia, Primary	low	3
Hyperalgia, Secondary	low	3
Hypertension	low	3
Hypertension, Renal	low	1
Hypertrophy, Right Ventricular	low	1
Hypogammaglobulinemia, Acquired	low	1
Hypolipoproteinemia	low	1
Hypolipoproteinemias	low	1
Hypoprebetalipoproteinemia	low	1
Immunodeficiency, Common Variable	low	1
Immunoglobulin Deficiency, Late-Onset	low	1
Inflammation	low	1
Injury, Myocardial Reperfusion	low	1
Innate Inflammatory Response	low	1
Intracranial Neoplasms	low	1
Kahler Disease	low	1
Keskushermoston sairaudet@fi	low	1
Lactotroph Adenoma	low	1
Left-Sided Heart Failure	low	1
Leukemia, Acute Myelogenous	low	2
Leukemia, Acute Myeloid	low	2
Leukemia, Acute Promyelocytic	low	7
Leukemia, Myeloblastic, Acute	low	2
Leukemia, Myelocytic, Acute	low	2
Leukemia, Myelogenous, Acute	low	2
Leukemia, Myeloid, Acute	low	2
Leukemia, Myeloid, Acute, M1	low	2
Leukemia, Myeloid, Acute, M2	low	2
Leukemia, Myeloid, Acute, M3	low	7
Leukemia, Nonlymphoblastic, Acute	low	2
Leukemia, Nonlymphocytic, Acute	low	2
Leukemia, Progranulocytic	low	7
Leukemia, Promyelocytic, Acute	low	7
Liver Cancer	low	3
Liver Cancer, Adult	low	2
Liver Cell Carcinoma	low	2
Liver Cell Carcinoma, Adult	low	2
Liver Neoplasms	low	3
Liver Neoplasms, Experimental	low	14
Lobar Pneumonia	low	1
Long QT Syndrome	low	1
Lung Inflammation	low	1
Lymphoma, T-Cell	low	3
M3 ANLL	low	7
Macroprolactinoma	low	1
MAIDS	low	1
Maladie du systu00E8me nerveux central@fr	low	1
Malattie del sistema nervoso centrale@it	low	1
Malignant Epithelial Neoplasms	low	1
Malignant Glioma	low	5
Malignant Melanoma	low	1
Malignant Neoplasm of Breast	low	1
Malignant Neoplasms, Brain	low	1
Malignant Primary Brain Neoplasms	low	1
Malignant Primary Brain Tumors	low	1
Malignant Tumor of Breast	low	1
Mammary Cancer	low	1
Mammary Carcinoma, Human	low	1
Mammary Neoplasm, Human	low	1
Mammary Neoplasms, Human	low	1
Mechanical Allodynia	low	3
Mechanical Hyperalgesia	low	3
Melanoma	low	1
Meningoencephalitis, Herpes Simplex Virus	low	1
Metabolic Acidosis	low	2
Microprolactinoma	low	1
Mixed Glioma	low	5
Molluscum Fibrosum	low	1
Monosomy, Partial	low	1
Mucoviscidosis	low	16
Multiple Myeloma	low	1
Murine Acquired Immune Deficiency Syndrome	low	1
Murine Acquired Immuno-Deficiency Syndrome	low	1
Murine Acquired Immunodeficiency Syndrome	low	1
Murine AIDS	low	1
Muscle Contraction	low	1
Muscle Relaxation	low	1
Muscular Atrophy, Adult Spinal	low	1
Muscular Atrophy, Spinal	low	1
Myeloblastic Leukemia, Acute	low	2
Myelocytic Leukemia, Acute	low	2
Myelogenous Leukemia, Acute	low	2
Myeloid Leukemia, Acute	low	2
Myeloid Leukemia, Acute, M1	low	2
Myeloid Leukemia, Acute, M2	low	2
Myeloid Leukemia, Acute, M3	low	7
Myeloma-Multiple	low	1
Myeloma, Multiple	low	1
Myeloma, Plasma-Cell	low	1
Myelomatosis	low	1
Myelopathic Muscular Atrophy	low	1
Myelopathic Muscular Atrophy, Progressive	low	1
Myocardial Failure	low	1
Myocardial Ischemic Reperfusion Injury	low	1
Myocardial Reperfusion Injury	low	1
Nasal Polyps	low	1
nemoci centru00E1lnu00EDho nervovu00E9ho systu00E9mu@cs	low	1
Neoplasms, Adrenal Gland	low	3
Neoplasms, Brain	low	1
Neoplasms, Brain, Benign	low	1
Neoplasms, Brain, Malignant	low	1
Neoplasms, Brain, Primary	low	1
Neoplasms, Breast	low	1
Neoplasms, Colonic	low	2
Neoplasms, Endometrial	low	1
Neoplasms, Experimental Liver	low	14
Neoplasms, Gastric	low	1
Neoplasms, Hepatic	low	3
Neoplasms, Intracranial	low	1
Neoplasms, Liver	low	3
Neoplasms, Malignant Epithelial	low	1
Neoplasms, Prostate	low	3
Neoplasms, Prostatic	low	3
Neoplasms, Stomach	low	1
Neoplasms, Uterine	low	1
Neoplasms, Uterus	low	1
Neoplastic Cell Transformation	low	2
Neoplastic Transformation, Cell	low	2
Neuroblastoma	low	4
Neurofibromatosis 1	low	1
Neurofibromatosis I	low	1
Neurofibromatosis Type 1	low	1
Neurofibromatosis Type I	low	1
Neurofibromatosis, Peripheral Type	low	1
Neurofibromatosis, Peripheral, NF 1	low	1
Neurofibromatosis, Peripheral, NF1	low	1
Neurofibromatosis, Type 1	low	1
Neurofibromatosis, Type I	low	1
NF1 (Neurofibromatosis 1)	low	1
Nonlymphoblastic Leukemia, Acute	low	2
Nonlymphocytic Leukemia, Acute	low	2
Obesity	low	1
Oculopharyngeal Spinal Muscular Atrophy	low	1
Optic Nerve Avulsion	low	1
Optic Nerve Contusion	low	1
Optic Nerve Injuries	low	1
Optic Nerve Transection	low	1
Optic Nerve Trauma	low	1
Optic Neuropathy, Traumatic	low	1
Pancreatic Cystic Fibrosis	low	16
Partial Monosomy	low	1
Peripheral Neurofibromatosis	low	1
Pheochromocytoma	low	3
Pheochromocytoma, Extra-Adrenal	low	3
Pituitary Adenoma	low	5
Pituitary Adenoma, Prolactin-Secreting	low	1
Pituitary Cancer	low	5
Pituitary Carcinoma	low	5
Pituitary Neoplasms	low	5
Pituitary Tumors	low	5
Plasma Cell Myeloma	low	1
Pneumonia	low	1
Pneumonia, Lobar	low	1
Pneumonitis	low	1
Pregnancy	low	8
Primary Brain Neoplasms	low	1
Primary Hyperaldosteronism	low	1
Primary Malignant Brain Neoplasms	low	1
Primary Malignant Brain Tumors	low	1
PRL-Secreting Pituitary Adenoma	low	1
Progranulocytic Leukemia	low	7
Progressive Muscular Atrophy	low	1
Progressive Myelopathic Muscular Atrophy	low	1
Progressive Proximal Myelopathic Muscular Atrophy	low	1
Prolactin-Producing Pituitary Adenoma	low	1
Prolactin-Secreting Pituitary Adenoma	low	1
Prolactinoma	low	1
Prolactinoma, Familial	low	1
Promyelocytic Leukemia, Acute	low	7
Prostate Cancer	low	3
Prostate Neoplasms	low	3
Prostatic Cancer	low	3
Prostatic Neoplasms	low	3
Proximal Myelopathic Muscular Atrophy, Progressive	low	1
Pulmonary Cystic Fibrosis	low	16
Pulmonary Inflammation	low	1
Pulmonic Stenosis with Cafe-au-Lait Spots	low	1
Recklinghausen Disease of Nerve	low	1
Recklinghausen Disease, Nerve	low	1
Recklinghausen's Disease of Nerve	low	1
Recklinghausens Disease of Nerve	low	1
Reperfusion Injury, Myocardial	low	1
Right Ventricular Hypertrophy	low	1
Right-Sided Heart Failure	low	1
Rigidity, Decerebrate	low	1
Rigidity, Decorticate	low	1
Scapuloperoneal Form of Spinal Muscular Atrophy	low	1
Scapuloperoneal Spinal Muscular Atrophy	low	1
Second Cranial Nerve Injuries	low	1
Second Cranial Nerve Trauma	low	1
Seizure Disorder	low	1
Spinal Amyotrophy	low	1
Spinal Muscular Atrophy	low	1
Spinal Muscular Atrophy, Distal	low	1
Spinal Muscular Atrophy, Oculopharyngeal	low	1
Spinal Muscular Atrophy, Scapuloperoneal	low	1
Spinal Muscular Atrophy, Scapuloperoneal Form	low	1
SREDIu0160NJI u017DIVu010CANI SUSTAV, BOLESTI@hr	low	1
Stomach Cancer	low	1
Stomach Neoplasms	low	1
Streptozocin Diabetes	low	3
Streptozotocin Diabetes	low	3
Substance Withdrawal Syndrome	low	1
Sykdommer i sentralnervesystemet@no	low	1
Symptom Cluster	low	1
Syndrome	low	1
T-Cell Lymphoma	low	3
Tachyarrhythmia	low	1
Tachycardia	low	1
Tactile Allodynia	low	3
Thermal Allodynia	low	3
Transformation, Neoplastic Cell	low	2
Transformation, Viral Cell	low	2
Translocation, Chromosomal	low	1
Translocation, Genetic	low	1
Trauma, Second Cranial Nerve	low	1
Tumorigenic Transformation	low	2
Tumors, Breast	low	1
u041Du0415u0420u0412u041Du041Eu0419 u0421u0418u0421u0422u0415u041Cu042B u0426u0415u041Du0422u0420u0410u041Bu042Cu041Du041Eu0419 u0411u041Eu041Bu0415u0417u041Du0418@ru	low	1
u4E2Du67A2u795Eu7D4Cu7CFBu75BEu60A3@ja	low	1
Uterine Cancer	low	1
Uterine Neoplasms	low	1
Uterus Cancer	low	1
Uterus Neoplasms	low	1
Ventricular Hypertrophy, Right	low	1
Viral Cell Transformation	low	2
von Recklinghausen Disease	low	1
von Recklinghausen's Disease	low	1
Wallerian Degeneration	low	1
Watson Syndrome	low	1
Withdrawal Symptoms	low	1
Zentralnervensystemkrankheiten@de	low	1
Ziekte, centraalzenuwstelsel-@nl	low	1