succinic acid has been researched along with Hypertension in 9 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amoxicillin treated rats had lower BP compared with untreated rats." | 1.56 | Exposure to Amoxicillin in Early Life Is Associated With Changes in Gut Microbiota and Reduction in Blood Pressure: Findings From a Study on Rat Dams and Offspring. ( Chakraborty, S; Cheng, X; Chiu, N; Galla, S; Joe, B; Mell, B; Vijay-Kumar, M; Wenceslau, CF; Yeo, JY, 2020) |
| "When hypertension was reduced using captopril, vitreoretinal succinate returned to baseline levels." | 1.40 | Cyclic stretch and hypertension increase retinal succinate: potential mechanisms for exacerbation of ocular neovascularization by mechanical stress. ( Kinoshita, H; Kitaoka, T; Kusano, M; Maekawa, Y; Maki, T; Matsumoto, M; Suzuma, K; Uematsu, M, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| He, W | 1 |
| Miao, FJ | 1 |
| Lin, DC | 1 |
| Schwandner, RT | 1 |
| Wang, Z | 1 |
| Gao, J | 1 |
| Chen, JL | 1 |
| Tian, H | 1 |
| Ling, L | 1 |
| Galla, S | 1 |
| Chakraborty, S | 1 |
| Cheng, X | 1 |
| Yeo, JY | 1 |
| Mell, B | 1 |
| Chiu, N | 1 |
| Wenceslau, CF | 1 |
| Vijay-Kumar, M | 1 |
| Joe, B | 1 |
| Carney, EF | 1 |
| Kinoshita, H | 1 |
| Suzuma, K | 1 |
| Maki, T | 1 |
| Maekawa, Y | 1 |
| Matsumoto, M | 1 |
| Kusano, M | 1 |
| Uematsu, M | 1 |
| Kitaoka, T | 1 |
| Tian, Z | 1 |
| Liu, Y | 1 |
| Usa, K | 1 |
| Mladinov, D | 1 |
| Fang, Y | 1 |
| Ding, X | 1 |
| Greene, AS | 1 |
| Cowley, AW | 1 |
| Liang, M | 1 |
| Akira, K | 2 |
| Masu, S | 1 |
| Imachi, M | 2 |
| Mitome, H | 1 |
| Hashimoto, T | 2 |
| Hebert, SC | 1 |
| Fujiwara, M | 1 |
| Arifuku, K | 1 |
| Ando, I | 1 |
| Nemoto, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of a Meat Versus Vegetarian Diet in 12 Healthy Volunteers on the Excretion of Alpha-ketoglutarate Measured in 24-hours Urine[NCT01880281] | 32 participants (Actual) | Interventional | 2013-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for succinic acid and Hypertension
| Article | Year |
|---|---|
Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors.
Topics: Animals; Antihypertensive Agents; Captopril; Cattle; Cell Line; Citric Acid Cycle; Cricetinae; Human | 2004 |
Exposure to Amoxicillin in Early Life Is Associated With Changes in Gut Microbiota and Reduction in Blood Pressure: Findings From a Study on Rat Dams and Offspring.
Topics: Age Factors; Amoxicillin; Animals; Anti-Bacterial Agents; Blood Pressure; Disease Models, Animal; Fe | 2020 |
Succinate homeostasis protects against lithogenesis and hypertension.
Topics: Blood Pressure; Calcium Oxalate; Homeostasis; Humans; Hypertension; Succinates; Succinic Acid | 2019 |
Cyclic stretch and hypertension increase retinal succinate: potential mechanisms for exacerbation of ocular neovascularization by mechanical stress.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme-Linke | 2014 |
Novel role of fumarate metabolism in dahl-salt sensitive hypertension.
Topics: Analysis of Variance; Animals; Biomarkers; Blotting, Western; Disease Models, Animal; DNA, Complemen | 2009 |
A metabonomic study of biochemical changes characteristic of genetically hypertensive rats based on (1)H NMR spectroscopic urinalysis.
Topics: Animals; Citric Acid; Creatine; Disease Progression; Hippurates; Hypertension; Magnetic Resonance Sp | 2012 |
Physiology: orphan detectors of metabolism.
Topics: Animals; Blood Pressure; Cell Respiration; Citric Acid Cycle; Humans; Hypertension; Ketoglutaric Aci | 2004 |
Investigations into biochemical changes of genetic hypertensive rats using 1H nuclear magnetic resonance-based metabonomics.
Topics: Animals; Citric Acid; Creatine; Creatinine; Dimethylamines; Disease Models, Animal; Hypertension; Ke | 2005 |
Pattern recognition analysis for classification of hypertensive model rats and diurnal variation using 1H-NMR spectroscopy of urine.
Topics: Animals; Circadian Rhythm; Citric Acid; Hypertension; Lactic Acid; Magnetic Resonance Spectroscopy; | 2005 |