Page last updated: 2024-11-04

tegafur and Hypertension

tegafur has been researched along with Hypertension in 7 studies

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"In Japan, a study comparing the effectiveness and safety of irinotecan plus S-1 (IRIS) with those of a combination of 5-fluorouracil, leucovorin, and irinotecan (FOLFIRI) as second-line treatment in patients with advanced or recurrent colorectal cancer demonstrated that IRIS was non-inferior to FOLFIRI."9.16Phase II study of combined chemotherapy with irinotecan and S-1 (IRIS) plus bevacizumab in patients with inoperable recurrent or advanced colorectal cancer. ( Fukushima, H; Hatanaka, K; Iwanaga, I; Kobayashi, Y; Komatsu, Y; Kudo, M; Meguro, T; Miyagishima, T; Munakata, M; Nakamura, M; Nakatsumi, H; Sakata, Y; Sogabe, S; Tateyama, M; Yuki, S, 2012)
"In Japan, a study comparing the effectiveness and safety of irinotecan plus S-1 (IRIS) with those of a combination of 5-fluorouracil, leucovorin, and irinotecan (FOLFIRI) as second-line treatment in patients with advanced or recurrent colorectal cancer demonstrated that IRIS was non-inferior to FOLFIRI."5.16Phase II study of combined chemotherapy with irinotecan and S-1 (IRIS) plus bevacizumab in patients with inoperable recurrent or advanced colorectal cancer. ( Fukushima, H; Hatanaka, K; Iwanaga, I; Kobayashi, Y; Komatsu, Y; Kudo, M; Meguro, T; Miyagishima, T; Munakata, M; Nakamura, M; Nakatsumi, H; Sakata, Y; Sogabe, S; Tateyama, M; Yuki, S, 2012)
"She was diagnosed with drug-induced thrombotic thrombocytopenic purpura (TTP)."1.39Drug-induced thrombotic thrombocytopenic purpura successfully treated with recombinant human soluble thrombomodulin. ( Fujimura, Y; Himeno, A; Hirata, H; Inoue, K; Kida, H; Kijima, T; Kumanogoh, A; Matsumoto, M; Nagatomo, I; Nishijima, Y; Otani, Y; Tachibana, I; Takahashi, R; Takeda, Y, 2013)
"Diabetes mellitus was diagnosed in 124 patients (50%) who had less distant metastasis and more hypertension."1.39Clinical outcomes of chemotherapy for diabetic and nondiabetic patients with pancreatic cancer: better prognosis with statin use in diabetic patients. ( Hirano, K; Ijichi, H; Isayama, H; Kawakubo, K; Kogure, H; Koike, K; Mizuno, S; Nakai, Y; Sasahira, N; Sasaki, T; Tada, M; Tateishi, K; Yamamoto, N, 2013)
" Adverse events were assessed by the National Cancer Institute Common Terminology Criteria for Adverse Events."1.37Retrospective cohort study on the safety and efficacy of bevacizumab with chemotherapy for metastatic colorectal cancer patients: the HGCSG0801 study. ( Asaka, M; Hatanaka, K; Hosokawa, A; Iwanaga, I; Kato, T; Komatsu, Y; Kusumi, T; Miyagishima, T; Nakamura, M; Sakata, Y; Sogabe, S; Yuki, S, 2011)
"He was diagnosed with advanced gastric cancer, T2N1H0P0M0, stage II."1.34[Complete response in an elderly patient with advanced gastric cancer treated with TS-1]. ( Fujiwara, S; Harada, K; Kawahara, K; Kitano, S; Moriyama, H; Noguchi, T, 2007)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's6 (85.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nishijima, Y1
Hirata, H1
Himeno, A1
Kida, H1
Matsumoto, M1
Takahashi, R1
Otani, Y1
Inoue, K1
Nagatomo, I1
Takeda, Y1
Kijima, T1
Tachibana, I1
Fujimura, Y1
Kumanogoh, A1
Hiraki, M1
Tanaka, M1
Sato, S1
Kai, K1
Morito, K1
Kobayashi, K1
Noshiro, H1
Tokunaga, O1
Miyazaki, K1
Kihara, K1
Kamimura, H1
Isayama, H2
Fujii, Y1
Iino, Y1
Sogabe, S2
Komatsu, Y2
Yuki, S2
Kusumi, T1
Hatanaka, K2
Nakamura, M2
Kato, T1
Miyagishima, T2
Hosokawa, A1
Iwanaga, I2
Sakata, Y2
Asaka, M1
Fukushima, H1
Nakatsumi, H1
Kobayashi, Y1
Kudo, M1
Munakata, M1
Meguro, T1
Tateyama, M1
Nakai, Y1
Sasaki, T1
Mizuno, S1
Sasahira, N1
Kogure, H1
Kawakubo, K1
Yamamoto, N1
Hirano, K1
Ijichi, H1
Tateishi, K1
Tada, M1
Koike, K1
Harada, K1
Noguchi, T1
Fujiwara, S1
Moriyama, H1
Kitano, S1
Kawahara, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Trial of Combination Therapy With Irinotecan, S-1, and Bevacizumab (IRIS/Bev) in Patients With Unresectable or Recurrent Colorectal Cancer[NCT00569790]Phase 253 participants (Actual)Interventional2007-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for tegafur and Hypertension

ArticleYear
Phase II study of combined chemotherapy with irinotecan and S-1 (IRIS) plus bevacizumab in patients with inoperable recurrent or advanced colorectal cancer.
    Acta oncologica (Stockholm, Sweden), 2012, Volume: 51, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined

2012

Other Studies

6 other studies available for tegafur and Hypertension

ArticleYear
Drug-induced thrombotic thrombocytopenic purpura successfully treated with recombinant human soluble thrombomodulin.
    Internal medicine (Tokyo, Japan), 2013, Volume: 52, Issue:10

    Topics: Acute Kidney Injury; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Antineoplastic Comb

2013
A complete response in small cell carcinoma of the esophagus treated by s-1/cisplatin combined chemotherapy and radiotherapy.
    Journal of gastrointestinal cancer, 2010, Volume: 41, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Asthma; Carcinoma, Small Cell; Cisplatin; Comb

2010
[Suppression of renin-angiotensin system and cancer therapy (discussion)].
    Nihon rinsho. Japanese journal of clinical medicine, 2010, Volume: 68, Issue:6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; B

2010
Retrospective cohort study on the safety and efficacy of bevacizumab with chemotherapy for metastatic colorectal cancer patients: the HGCSG0801 study.
    Japanese journal of clinical oncology, 2011, Volume: 41, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclo

2011
Clinical outcomes of chemotherapy for diabetic and nondiabetic patients with pancreatic cancer: better prognosis with statin use in diabetic patients.
    Pancreas, 2013, Volume: 42, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Antineoplastic Combined Chemotherapy Protoc

2013
[Complete response in an elderly patient with advanced gastric cancer treated with TS-1].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:3

    Topics: Adenocarcinoma; Aged, 80 and over; Antimetabolites, Antineoplastic; Diabetes Complications; Drug Adm

2007