Page last updated: 2024-11-01

ondansetron and Hypertension

ondansetron has been researched along with Hypertension in 6 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"The potency of Ondansetron (Zofran, Glaxo), a highly specific 5HT3 antagonist in preventing the very unfavorable complication during introducing anesthesia, i."3.68Evaluation of ondansetron as a drug for premedication. ( Kamenova, E, 1993)
"Ondansetron is an antagonist of 5-HT3 receptors mostly used as an antiemetic yet known to modulate metabolism and appetite."1.38Differential effects of 5-HT3 receptor antagonist on lipid profile in spontaneously hypertensive rat and chromosome 8 congenic strain. ( Kren, V; Krenova, D; Krupkova, M; Liska, F; Seda, O; Sedova, L, 2012)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bordlee, JW1
Beakley, BD1
Mody, R1
McConville, AP1
Weed, JT1
McClure, BP1
Foldes, PJ1
Ma, JG1
Kaye, AD1
Eskander, JP1
Alzoubi, KH1
Aleisa, AM2
Alkadhi, KA2
Krupkova, M1
Sedova, L1
Liska, F1
Krenova, D1
Kren, V1
Seda, O1
Gerges, NZ1
Alhaider, AA1
Kamenova, E1
Tsukamoto, K1
Kurihara, T1
Nakayama, N1
Isogai, O1
Ito, S1
Komatsu, K1
Kanmatsuse, K1

Other Studies

6 other studies available for ondansetron and Hypertension

ArticleYear
A case of paradoxical presentation of a postural postdural puncture headache after combined spinal-epidural anesthesia.
    Journal of clinical anesthesia, 2017, Volume: 38

    Topics: Acetaminophen; Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia,

2017
In vivo expression of ganglionic long-term potentiation in superior cervical ganglia from hypertensive aged rats.
    Neurobiology of aging, 2010, Volume: 31, Issue:5

    Topics: Aging; Animals; Blood Pressure; Blotting, Western; Calcineurin; Calcium-Calmodulin-Dependent Protein

2010
Differential effects of 5-HT3 receptor antagonist on lipid profile in spontaneously hypertensive rat and chromosome 8 congenic strain.
    Neuro endocrinology letters, 2012, Volume: 33 Suppl 2

    Topics: Animals; Animals, Congenic; Chromosomes, Mammalian; Disease Models, Animal; Glucose Intolerance; Hyp

2012
Reduction of elevated arterial blood pressure in obese Zucker rats by inhibition of ganglionic long-term potentiation.
    Neuropharmacology, 2002, Volume: 43, Issue:7

    Topics: Animals; Blood Pressure; Ganglia; Hypertension; In Vitro Techniques; Long-Term Potentiation; Male; O

2002
Evaluation of ondansetron as a drug for premedication.
    Acta physiologica et pharmacologica Bulgarica, 1993, Volume: 19, Issue:3

    Topics: Adult; Aged; Anesthesia; Bradycardia; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged;

1993
Pressor responses to serotonin injected into the nucleus tractus solitarius of Sprague-Dawley rats and spontaneously hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2000, Volume: 22, Issue:1

    Topics: Animals; Baroreflex; Bicuculline; Blood Pressure; Free Radical Scavengers; GABA Antagonists; Hyperte

2000