trimethylamine has been researched along with Hypertension in 9 studies
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The association of total choline (TC) intake and its metabolite trimethylamine-N-oxide (TMAO) with hypertension and blood pressure (BP) has not been elucidated." | 8.12 | Association of Choline Intake with Blood Pressure and Effects of Its Microbiota-Dependent Metabolite Trimethylamine-N-Oxide on Hypertension. ( Feng, YQ; He, GD; Liu, XC; Lu, AS, 2022) |
| "Gut microbiota-dependent metabolites, in particular trimethylamine (TMA), are linked to hypertension." | 7.96 | Targeting on Gut Microbiota-Derived Metabolite Trimethylamine to Protect Adult Male Rat Offspring against Hypertension Programmed by Combined Maternal High-Fructose Intake and Dioxin Exposure. ( Chan, JYH; Chang-Chien, GP; Hou, CY; Hsu, CN; Lee, WC; Lin, S; Tain, YL; Wu, KLH; Yu, HR, 2020) |
| "Alterations of gut metabolites, such as SCFAs and trimethylamine (TMA), and microbial composition are associated with the development of hypertension." | 7.91 | Targeting on Gut Microbial Metabolite Trimethylamine-N-Oxide and Short-Chain Fatty Acid to Prevent Maternal High-Fructose-Diet-Induced Developmental Programming of Hypertension in Adult Male Offspring. ( Chang-Chien, GP; Hou, CY; Hsu, CN; Lin, S; Tain, YL, 2019) |
| "Offspring hypertension is associated with increases in the plasma TMAO concentration and oxidative stress and shifts in gut microbiota." | 5.91 | Iodomethylcholine Inhibits Trimethylamine-N-Oxide Production and Averts Maternal Chronic Kidney Disease-Programmed Offspring Hypertension. ( Chang-Chien, GP; Hou, CY; Hsu, CN; Lin, S; Tain, YL, 2023) |
| "The association of total choline (TC) intake and its metabolite trimethylamine-N-oxide (TMAO) with hypertension and blood pressure (BP) has not been elucidated." | 4.12 | Association of Choline Intake with Blood Pressure and Effects of Its Microbiota-Dependent Metabolite Trimethylamine-N-Oxide on Hypertension. ( Feng, YQ; He, GD; Liu, XC; Lu, AS, 2022) |
| "Increased levels of lactic acid, pyruvate, and TMAO may be related to the pathophysiological changes in the minor ischaemic stroke population." | 4.12 | Related factors based on non-targeted metabolomics methods in minor ischaemic stroke. ( Chen, C; Ding, L; Guo, J; Liu, H; Ma, Y; Qiao, X; Wang, J; Wang, M; Yang, T; Zhao, S, 2022) |
| "Gut microbiota-dependent metabolites, in particular trimethylamine (TMA), are linked to hypertension." | 3.96 | Targeting on Gut Microbiota-Derived Metabolite Trimethylamine to Protect Adult Male Rat Offspring against Hypertension Programmed by Combined Maternal High-Fructose Intake and Dioxin Exposure. ( Chan, JYH; Chang-Chien, GP; Hou, CY; Hsu, CN; Lee, WC; Lin, S; Tain, YL; Wu, KLH; Yu, HR, 2020) |
| "Alterations of gut metabolites, such as SCFAs and trimethylamine (TMA), and microbial composition are associated with the development of hypertension." | 3.91 | Targeting on Gut Microbial Metabolite Trimethylamine-N-Oxide and Short-Chain Fatty Acid to Prevent Maternal High-Fructose-Diet-Induced Developmental Programming of Hypertension in Adult Male Offspring. ( Chang-Chien, GP; Hou, CY; Hsu, CN; Lin, S; Tain, YL, 2019) |
| "Offspring hypertension is associated with increases in the plasma TMAO concentration and oxidative stress and shifts in gut microbiota." | 1.91 | Iodomethylcholine Inhibits Trimethylamine-N-Oxide Production and Averts Maternal Chronic Kidney Disease-Programmed Offspring Hypertension. ( Chang-Chien, GP; Hou, CY; Hsu, CN; Lin, S; Tain, YL, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 5 (55.56) | 2.80 |
| Authors | Studies |
|---|---|
| Li, D | 1 |
| Lu, Y | 1 |
| Yuan, S | 1 |
| Cai, X | 1 |
| He, Y | 1 |
| Chen, J | 1 |
| Wu, Q | 1 |
| He, D | 1 |
| Fang, A | 1 |
| Bo, Y | 1 |
| Song, P | 1 |
| Bogaert, D | 1 |
| Tsilidis, K | 1 |
| Larsson, SC | 1 |
| Yu, H | 1 |
| Zhu, H | 1 |
| Theodoratou, E | 1 |
| Zhu, Y | 1 |
| Li, X | 1 |
| He, GD | 1 |
| Liu, XC | 1 |
| Lu, AS | 1 |
| Feng, YQ | 1 |
| Chen, C | 1 |
| Qiao, X | 1 |
| Guo, J | 1 |
| Yang, T | 1 |
| Wang, M | 1 |
| Ma, Y | 1 |
| Zhao, S | 1 |
| Ding, L | 1 |
| Liu, H | 1 |
| Wang, J | 1 |
| Tain, YL | 3 |
| Chang-Chien, GP | 3 |
| Lin, S | 3 |
| Hou, CY | 3 |
| Hsu, CN | 3 |
| Chan, JYH | 1 |
| Yu, HR | 1 |
| Lee, WC | 1 |
| Wu, KLH | 1 |
| Cashman, JR | 1 |
| Camp, K | 1 |
| Fakharzadeh, SS | 1 |
| Fennessey, PV | 1 |
| Hines, RN | 1 |
| Mamer, OA | 1 |
| Mitchell, SC | 1 |
| Nguyen, GP | 1 |
| Schlenk, D | 1 |
| Smith, RL | 1 |
| Tjoa, SS | 1 |
| Williams, DE | 1 |
| Yannicelli, S | 1 |
| Dolan, C | 1 |
| Shields, DC | 1 |
| Stanton, A | 1 |
| O'Brien, E | 1 |
| Lambert, DM | 1 |
| O'Brien, JK | 1 |
| Treacy, EP | 1 |
| Bamosa, AO | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of a Whole Food Based Nutritional Formulation on Trimethylamine N-oxide and Cardiometabolic Endpoints in Healthy Adults.[NCT05795946] | 45 participants (Anticipated) | Interventional | 2023-04-15 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for trimethylamine and Hypertension
| Article | Year |
|---|---|
Gut microbiota-derived metabolite trimethylamine-N-oxide and multiple health outcomes: an umbrella review and updated meta-analysis.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Gastrointestinal Microbiome; Humans; Hypertension; Methy | 2022 |
Biochemical and clinical aspects of the human flavin-containing monooxygenase form 3 (FMO3) related to trimethylaminuria.
Topics: Animals; Clinical Trials as Topic; Diet; Genotype; Humans; Hypertension; Liver; Metabolic Diseases; | 2003 |
7 other studies available for trimethylamine and Hypertension
| Article | Year |
|---|---|
Association of Choline Intake with Blood Pressure and Effects of Its Microbiota-Dependent Metabolite Trimethylamine-N-Oxide on Hypertension.
Topics: Animals; Blood Pressure; Choline; Hypertension; Methylamines; Microbiota; Nutrition Surveys; Oxides; | 2022 |
Related factors based on non-targeted metabolomics methods in minor ischaemic stroke.
Topics: Biomarkers; Blood Glucose; Brain Ischemia; C-Reactive Protein; Homocysteine; Humans; Hypertension; I | 2022 |
Iodomethylcholine Inhibits Trimethylamine-N-Oxide Production and Averts Maternal Chronic Kidney Disease-Programmed Offspring Hypertension.
Topics: Animals; Female; Humans; Hypertension; Hypertrophy; Methylamines; Oxides; Pregnancy; Rats; Renal Ins | 2023 |
Targeting on Gut Microbiota-Derived Metabolite Trimethylamine to Protect Adult Male Rat Offspring against Hypertension Programmed by Combined Maternal High-Fructose Intake and Dioxin Exposure.
Topics: Animals; Diet, Carbohydrate Loading; Dioxins; Female; Fructose; Gastrointestinal Microbiome; Hyperte | 2020 |
Targeting on Gut Microbial Metabolite Trimethylamine-N-Oxide and Short-Chain Fatty Acid to Prevent Maternal High-Fructose-Diet-Induced Developmental Programming of Hypertension in Adult Male Offspring.
Topics: Acetates; Animals; Blood Pressure; Dietary Supplements; Fatty Acids, Volatile; Female; Fructose; Gas | 2019 |
Polymorphisms of the Flavin containing monooxygenase 3 (FMO3) gene do not predispose to essential hypertension in Caucasians.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Case-Control Studies; Genetic Predispositio | 2005 |
Response of the portal vein of spontaneous hypertensive rats to intracellular pH.
Topics: Ammonium Chloride; Animals; Hydrogen-Ion Concentration; Hypertension; In Vitro Techniques; Methylami | 1996 |