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piretanide and Hypertension

piretanide has been researched along with Hypertension in 37 studies

piretanide: potent inhibitor of chloride transport; structure

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"To test the dose responses of piretanide, ramipril, and their combination in patients with essential hypertension, a prospective, randomized, double-blind, placebo-controlled trial was conducted in 480 patients."9.07Usefulness of piretanide plus ramipril for systemic hypertension: a multicenter trial. ( Faulhaber, HD; Homuth, V; Löffler, K; Loose, U; Luft, FC, 1993)
"In a randomized, double-blind parallel group study the 24-hour hypotensive effect of piretanide and its influence on biochemical variables were compared with those of placebo in patients with mild to moderate essential hypertension."9.06Piretanide in the treatment of essential hypertension. A double-blind comparison versus placebo. ( Beloso, M; Bender, R; Garduno, D; Maass, L; Rangoonwala, B; Verho, M, 1986)
"A multi-centre, randomized, double-blind, parallel group study was undertaken in order to assess efficacy and tolerability of ramipril as compared to enalapril in mild to moderate hypertension."9.06A multi-centre comparative study between ramipril and enalapril in patients with mild to moderate essential hypertension. ( Akbary, MA; Rangoonwala, B; Rosenfeld, J; Schinzel, S; Zabludowski, J, 1988)
"A double-blind crossover study was carried out in 20 patients with mild to moderate essential hypertension to assess the efficacy and tolerability of a low fixed-dose combination containing 20 mg penbutolol (a beta-blocking agent) and 3 mg piretanide (a diuretic) in comparison to placebo over a period of 4 weeks."9.06Efficacy of a low fixed-dose combination of penbutolol with piretanide in the treatment of mild to moderate hypertension: a double-blind study against placebo. ( Rangoonwala, B; Verho, M; Yasky, J, 1986)
"The antihypertensive efficacy and tolerability of a fixed-dose combination containing 40 mg penbutolol (a beta-blocking agent) and 6 mg piretanide (a diuretic) in comparison to placebo was investigated in a double-blind, crossover study in 20 patients with mild to moderate essential hypertension."9.06Efficacy of a fixed-dose combination of 40 mg penbutolol with 6 mg piretanide in the treatment of mild to moderate hypertension: a double-blind study against placebo. ( Rangoonwala, B; Verho, M; Yasky, J, 1987)
"A double-blind trial was carried out in three parallel groups of patients with mild to moderate hypertension to assess the efficacy and tolerance of piretanide given as a single dose of 3 mg, 6 mg or 12 mg per day over a period of 12 weeks."9.05A double-blind study of piretanide in the treatment of hypertension. ( Dols, W; Freude, J; Rangoonwala, B; Verho, M, 1983)
"The efficacy and tolerability of penbutolol alone and in combination with piretanide at two dose levels were investigated in a double-blind parallel group study in patients with mild to moderate essential hypertension."9.05Efficacy of penbutolol + piretanide combinations in the treatment of arterial hypertension. ( Freude, J; Häringer, E; Pahnke, K; Rangoonwala, B; Verho, M, 1985)
"The metabolic effects of piretanide (2 x 6 mg daily) were compared with those of hydrochlorothiazide, in doses of 2 x 25 mg or 2 x 50 mg daily, in a double-blind study consisting of three parallel groups totalling 15 patients with uncomplicated essential hypertension."9.05The effects of piretanide on catecholamine metabolism, plasma renin activity and serum aldosterone: a double-blind pilot comparison against hydrochlorothiazide in patients with essential hypertension. ( Bückert, C; Kirsten, R; Verho, M, 1984)
"In a randomised double blind study in patients with mild to moderate hypertension, piretanide 6 mg once and twice daily significantly reduced both supine and erect blood pressure."9.05Single and divided daily dose piretanide in the treatment of uncomplicated essential hypertension: a double-blind comparison with a combination of hydrochlorothiazide and amiloride. ( Dols, W; Rangoonwala, B; Verho, M, 1985)
"In a randomized, double blind, parallel group study in out patients with mild to moderate essential hypertension the effects of piretanide on serum electrolytes and on blood pressure were compared with those of triamterene alone and the combination piretanide + triamterene."9.05Piretanide, a potassium stable diuretic, in the treatment of essential hypertension. ( Dols, W; Fratzer, U; Kaczynski, J; Mühlhäusler, W; Rangoonwala, B; Verho, M, 1984)
"A double-blind study was carried out in two parallel groups of patients with mild to moderate hypertension to assess the efficacy and tolerance of the combination 20 mg penbutolol plus 3 mg piretanide in comparison to 40 mg penbutolol alone over a period of 6 weeks."9.05Efficacy of penbutolol and a combination of a low dose of penbutolol with piretanide in the treatment of mild to moderate hypertension. ( Englert, R; Graml, E; Häringer, E; Pahnke, K; Rangoonwala, B; Verho, M, 1985)
"In a randomized double-blind parallel group study the effects of two formulations of piretanide (standard tablet and slow-release capsule) were compared in patients with mild to moderate essential hypertension."9.05Piretanide, a potassium stable diuretic, in the treatment of essential hypertension: a double-blind comparison of two formulations. ( Dols, W; Jaeger, S; Rangoonwala, B; Verho, M, 1985)
"A single-blind study was carried out in 22 out-patients with mild to moderate hypertension to investigate the effects of piretanide capsules on systolic and diastolic blood pressure during standardized ergometric and isometric exercise."7.67The effects of piretanide capsules on blood pressure during ergometric and isometric work loads in patients with mild to moderate essential hypertension. ( Maass, L; Meywald, W; Rangoonwala, B; Verho, M, 1985)
"Piretanide presented in 6 mg sustained-release capsules was administered twice daily for 12 weeks as antihypertensive monotherapy to 16 patients with mild-to-moderate hypertension."7.66Piretanide in the treatment of hypertension. Effects on arterial blood pressure and several blood variables. ( Leary, WP; Reyes, AJ, 1981)
" The purpose of the present study was to examine whether long-term therapy with ramipril (RA, and ACE inhibitor) would lower blood pressure more effectively and without adverse reactions in combination with the loop diuretics piretanide (PI) or furosemide (FU)."5.28Loop diuretics combined with an ACE inhibitor for treatment of hypertension: a study with furosemide, piretanide, and ramipril in spontaneously hypertensive rats. ( Baldes, L; Becker, RH; Treudler, M, 1989)
"To test the dose responses of piretanide, ramipril, and their combination in patients with essential hypertension, a prospective, randomized, double-blind, placebo-controlled trial was conducted in 480 patients."5.07Usefulness of piretanide plus ramipril for systemic hypertension: a multicenter trial. ( Faulhaber, HD; Homuth, V; Löffler, K; Loose, U; Luft, FC, 1993)
"The antihypertensive efficacy and tolerability of a fixed-dose combination containing 40 mg penbutolol (a beta-blocking agent) and 6 mg piretanide (a diuretic) in comparison to placebo was investigated in a double-blind, crossover study in 20 patients with mild to moderate essential hypertension."5.06Efficacy of a fixed-dose combination of 40 mg penbutolol with 6 mg piretanide in the treatment of mild to moderate hypertension: a double-blind study against placebo. ( Rangoonwala, B; Verho, M; Yasky, J, 1987)
"In a randomized, double-blind parallel group study the 24-hour hypotensive effect of piretanide and its influence on biochemical variables were compared with those of placebo in patients with mild to moderate essential hypertension."5.06Piretanide in the treatment of essential hypertension. A double-blind comparison versus placebo. ( Beloso, M; Bender, R; Garduno, D; Maass, L; Rangoonwala, B; Verho, M, 1986)
"The haemodynamic effects of piretanide, acebutolol and nifedipine were tested and compared at rest and on exercise in an open study of patients with essential hypertension, grade II (WHO)."5.06[Modification of resting and effort hemodynamics in essential arterial hypertension using antihypertensive agents]. ( Wiechmann, HW, 1987)
"A double-blind crossover study was carried out in 20 patients with mild to moderate essential hypertension to assess the efficacy and tolerability of a low fixed-dose combination containing 20 mg penbutolol (a beta-blocking agent) and 3 mg piretanide (a diuretic) in comparison to placebo over a period of 4 weeks."5.06Efficacy of a low fixed-dose combination of penbutolol with piretanide in the treatment of mild to moderate hypertension: a double-blind study against placebo. ( Rangoonwala, B; Verho, M; Yasky, J, 1986)
"A double-blind parallel group study was carried out in patients with mild to moderate hypertension to assess the effects of 6 mg piretanide once or twice daily, in comparison to 50 mg hydrochlorothiazide plus 5 mg amiloride once daily, on serum trace-element levels over a period of three months."5.06Serum trace-element levels in piretanide-treated hypertensives: a double-blind trial against hydrochlorothiazide plus amiloride. ( Bossaller, W; Heinen, B; Verho, M, 1987)
"In a double-blind parallel group study carried out on 47 patients with mild to moderate essential hypertension, the effects of 6 mg piretanide once or twice daily on serum selenium levels were compared with 50 mg hydrochlorothiazide plus 5 mg amiloride before treatment and after 6 and 12 weeks of treatment."5.06Serum selenium levels in diuretic-treated hypertensives: a double-blind trial of piretanide against hydrochlorothiazide plus amiloride. ( Bossaller, W; Malerczyk, V; Verho, M, 1988)
"A multi-centre, randomized, double-blind, parallel group study was undertaken in order to assess efficacy and tolerability of ramipril as compared to enalapril in mild to moderate hypertension."5.06A multi-centre comparative study between ramipril and enalapril in patients with mild to moderate essential hypertension. ( Akbary, MA; Rangoonwala, B; Rosenfeld, J; Schinzel, S; Zabludowski, J, 1988)
"The metabolic effects of piretanide (2 x 6 mg daily) were compared with those of hydrochlorothiazide, in doses of 2 x 25 mg or 2 x 50 mg daily, in a double-blind study consisting of three parallel groups totalling 15 patients with uncomplicated essential hypertension."5.05The effects of piretanide on catecholamine metabolism, plasma renin activity and serum aldosterone: a double-blind pilot comparison against hydrochlorothiazide in patients with essential hypertension. ( Bückert, C; Kirsten, R; Verho, M, 1984)
"In a randomized, double blind, parallel group study in out patients with mild to moderate essential hypertension the effects of piretanide on serum electrolytes and on blood pressure were compared with those of triamterene alone and the combination piretanide + triamterene."5.05Piretanide, a potassium stable diuretic, in the treatment of essential hypertension. ( Dols, W; Fratzer, U; Kaczynski, J; Mühlhäusler, W; Rangoonwala, B; Verho, M, 1984)
"In a randomized double-blind parallel group study the effects of two formulations of piretanide (standard tablet and slow-release capsule) were compared in patients with mild to moderate essential hypertension."5.05Piretanide, a potassium stable diuretic, in the treatment of essential hypertension: a double-blind comparison of two formulations. ( Dols, W; Jaeger, S; Rangoonwala, B; Verho, M, 1985)
"A double-blind study was carried out in two parallel groups of patients with mild to moderate hypertension to assess the efficacy and tolerance of the combination 20 mg penbutolol plus 3 mg piretanide in comparison to 40 mg penbutolol alone over a period of 6 weeks."5.05Efficacy of penbutolol and a combination of a low dose of penbutolol with piretanide in the treatment of mild to moderate hypertension. ( Englert, R; Graml, E; Häringer, E; Pahnke, K; Rangoonwala, B; Verho, M, 1985)
"In a randomised double blind study in patients with mild to moderate hypertension, piretanide 6 mg once and twice daily significantly reduced both supine and erect blood pressure."5.05Single and divided daily dose piretanide in the treatment of uncomplicated essential hypertension: a double-blind comparison with a combination of hydrochlorothiazide and amiloride. ( Dols, W; Rangoonwala, B; Verho, M, 1985)
"The efficacy and tolerability of penbutolol alone and in combination with piretanide at two dose levels were investigated in a double-blind parallel group study in patients with mild to moderate essential hypertension."5.05Efficacy of penbutolol + piretanide combinations in the treatment of arterial hypertension. ( Freude, J; Häringer, E; Pahnke, K; Rangoonwala, B; Verho, M, 1985)
"A double-blind trial was carried out in three parallel groups of patients with mild to moderate hypertension to assess the efficacy and tolerance of piretanide given as a single dose of 3 mg, 6 mg or 12 mg per day over a period of 12 weeks."5.05A double-blind study of piretanide in the treatment of hypertension. ( Dols, W; Freude, J; Rangoonwala, B; Verho, M, 1983)
"The effect of antihypertensive treatment with 6-12 mg of the loop diuretic piretanide over 12 weeks on Na+-Li+ countertransport, and on extra- and intracellular electrolyte composition was studied in 10 previously untreated patients with essential hypertension."3.67Na+-Li+ countertransport and electrolyte composition in erythrocytes of patients with essential hypertension before and after antihypertensive treatment. ( Beuckelmann, D; Erdmann, E, 1986)
"The effect of a new diuretic, piretanide, on glucose tolerance, insulin secretion and 125I-insulin binding to erythrocytes was studied in 12 male patients with mild essential hypertension."3.67Effects of a new diuretic piretanide on glucose tolerance, insulin secretion and 125I-insulin binding. ( Harno, K; Välimäki, M; Verho, M, 1985)
"Intra-arterial blood pressure (IABP), baroreflex sensitivity and set point were measured in nine patients with essential hypertension during a control period and then after acute (4 h after a 12 mg oral dose) and chronic (after 3 months) treatment with the loop diuretic piretanide, mean dose 10 mg."3.67Acute and chronic effects of the loop diuretic, piretanide, on baroreflex set point and sensitivity in hypertensive man. ( Littler, WA; Watson, RD; Young, MA, 1985)
"A single-blind study was carried out in 22 out-patients with mild to moderate hypertension to investigate the effects of piretanide capsules on systolic and diastolic blood pressure during standardized ergometric and isometric exercise."3.67The effects of piretanide capsules on blood pressure during ergometric and isometric work loads in patients with mild to moderate essential hypertension. ( Maass, L; Meywald, W; Rangoonwala, B; Verho, M, 1985)
"Piretanide presented in 6 mg sustained-release capsules was administered twice daily for 12 weeks as antihypertensive monotherapy to 16 patients with mild-to-moderate hypertension."3.66Piretanide in the treatment of hypertension. Effects on arterial blood pressure and several blood variables. ( Leary, WP; Reyes, AJ, 1981)
" Eumagnesaemia and eupotassaemia were preserved at all dosage of the piretanide monosubstance."2.66Lack of effect of piretanide (a potassium-stable diuretic) on serum magnesium. ( de Looze, S; Irmisch, R; Rangoonwala, B; Verho, M, 1987)
"Piretanide is a potent 'loop' diuretic whose principal site of action is in the thick ascending limb of the loop of Henle."2.37Piretanide. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. ( Brogden, RN; Clissold, SP, 1985)
" HPC-EC10 (5:3) microcapsules containing piretanide were satisfactory as a sustained-release preparation in the light of the anti hypertensive effect even at a half frequency of daily dosing of the solution."1.28Pharmacological evaluation of hydroxypropylcellulose-ethylcellulose microcapsules containing piretanide. ( Goto, S; Kawata, M; Kuriki, T; Suzuki, N; Tsujiyama, T, 1990)
" The purpose of the present study was to examine whether long-term therapy with ramipril (RA, and ACE inhibitor) would lower blood pressure more effectively and without adverse reactions in combination with the loop diuretics piretanide (PI) or furosemide (FU)."1.28Loop diuretics combined with an ACE inhibitor for treatment of hypertension: a study with furosemide, piretanide, and ramipril in spontaneously hypertensive rats. ( Baldes, L; Becker, RH; Treudler, M, 1989)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199031 (83.78)18.7374
1990's5 (13.51)18.2507
2000's0 (0.00)29.6817
2010's1 (2.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Musini, VM1
Rezapour, P1
Wright, JM1
Bassett, K1
Jauca, CD1
Dols, W4
Freude, J2
Verho, M16
Rangoonwala, B12
Buckert, C2
Muhlhausler, W2
Fratzer, U2
Kirsten, R1
Kaczynski, J1
Zidek, W3
Losse, H3
Schmidt, W1
Fehske, KJ2
Vetter, H3
Baumgart, P2
Karoff, C2
Radaelli, L1
Cosci, P1
Grillo, C1
Bertoli, S1
Minetti, L1
Leary, WP1
Reyes, AJ1
Thijs, L1
Celis, H1
Kiowski, W1
Löffler, K2
Middeke, M1
Schulz, W1
Staessen, J1
Amery, A1
Bellaïche, G1
Lamouri, N1
Slama, JL1
Ley, G1
Paugam, B1
Homuth, V1
Faulhaber, HD1
Loose, U1
Luft, FC1
Tsujiyama, T1
Suzuki, N1
Kuriki, T1
Kawata, M1
Goto, S1
Becker, RH1
Baldes, L1
Treudler, M1
Zabludowski, J1
Rosenfeld, J1
Akbary, MA1
Schinzel, S1
Häcker, W1
Bossaller, W2
Malerczyk, V1
Wiechmann, HW2
Heinen, B1
Irmisch, R1
de Looze, S1
Beloso, M1
Maass, L2
Bender, R1
Garduno, D1
Yasky, J2
Beuckelmann, D1
Erdmann, E1
Jaeger, S1
Harno, K1
Välimäki, M1
Clissold, SP1
Brogden, RN1
Graml, E1
Englert, R1
Häringer, E2
Pahnke, K2
Meyer, BH1
Müller, FO1
Werkman, IM1
Luus, HG1
Lötter, MG1
Grigoleit, HG1
Young, MA1
Watson, RD1
Littler, WA1
Scholz, W1
Hropot, M1
Meywald, W1

Reviews

2 reviews available for piretanide and Hypertension

ArticleYear
Blood pressure-lowering efficacy of loop diuretics for primary hypertension.
    The Cochrane database of systematic reviews, 2015, May-22, Issue:5

    Topics: Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Furosemide; Humans; Hyper

2015
Piretanide. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.
    Drugs, 1985, Volume: 29, Issue:6

    Topics: Angina Pectoris; Animals; Blood Glucose; Diuretics; Dogs; Edema; Heart Failure; Humans; Hypertension

1985

Trials

21 trials available for piretanide and Hypertension

ArticleYear
A double-blind study of piretanide in the treatment of hypertension.
    Current medical research and opinion, 1983, Volume: 8, Issue:9

    Topics: Adult; Aged; Blood Pressure; Body Weight; Clinical Trials as Topic; Diuretics; Double-Blind Method;

1983
A double-blind multicentre study of piretanide and hydrochlorothiazide in patients with essential hypertension.
    The Journal of international medical research, 1984, Volume: 12, Issue:2

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Female; Human

1984
The effects of piretanide on catecholamine metabolism, plasma renin activity and serum aldosterone: a double-blind pilot comparison against hydrochlorothiazide in patients with essential hypertension.
    Pharmatherapeutica, 1984, Volume: 3, Issue:9

    Topics: Aged; Aldosterone; Blood Pressure; Catecholamines; Diuretics; Dopamine; Double-Blind Method; Female;

1984
Piretanide, a potassium stable diuretic, in the treatment of essential hypertension.
    European journal of clinical pharmacology, 1984, Volume: 27, Issue:4

    Topics: Adult; Aged; Blood Pressure; Body Weight; Calcium; Clinical Trials as Topic; Diuretics; Double-Blind

1984
Double-blind comparison of antihypertensive treatment with ramipril and piretanide, given alone or in combination.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:1

    Topics: Adult; Aged; Antihypertensive Agents; Blood Chemical Analysis; Blood Pressure; Diuretics; Double-Bli

1995
Usefulness of piretanide plus ramipril for systemic hypertension: a multicenter trial.
    The American journal of cardiology, 1993, Sep-15, Volume: 72, Issue:9

    Topics: Adult; Aged; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug

1993
A multi-centre comparative study between ramipril and enalapril in patients with mild to moderate essential hypertension.
    Current medical research and opinion, 1988, Volume: 11, Issue:2

    Topics: Adult; Aged; Antihypertensive Agents; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Diuretics;

1988
Intracellular sodium and calcium during antihypertensive treatment.
    Klinische Wochenschrift, 1985, Volume: 63 Suppl 3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Body Fluids; Calcium; Erythrocytes; Humans; Hype

1985
Serum selenium levels in diuretic-treated hypertensives: a double-blind trial of piretanide against hydrochlorothiazide plus amiloride.
    International journal of clinical pharmacology research, 1988, Volume: 8, Issue:1

    Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Diuretics; Double-Blind Method; Humans; Hydrochlor

1988
[Hemodynamic effects of different antihypertensive combinations].
    Deutsche medizinische Wochenschrift (1946), 1988, Jun-24, Volume: 113, Issue:25

    Topics: Acebutolol; Antihypertensive Agents; Captopril; Chronic Disease; Diuretics; Drug Evaluation; Drug Th

1988
Serum trace-element levels in piretanide-treated hypertensives: a double-blind trial against hydrochlorothiazide plus amiloride.
    International journal of clinical pharmacology research, 1987, Volume: 7, Issue:1

    Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Diuretics; Double-Blind Method; Humans; Hydrochlor

1987
Lack of effect of piretanide (a potassium-stable diuretic) on serum magnesium.
    International journal of clinical pharmacology research, 1987, Volume: 7, Issue:6

    Topics: Amiloride; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension;

1987
Piretanide in the treatment of essential hypertension. A double-blind comparison versus placebo.
    Drugs under experimental and clinical research, 1986, Volume: 12, Issue:5

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Administ

1986
Efficacy of a fixed-dose combination of 40 mg penbutolol with 6 mg piretanide in the treatment of mild to moderate hypertension: a double-blind study against placebo.
    Current medical research and opinion, 1987, Volume: 10, Issue:6

    Topics: Adult; Aged; Blood Pressure; Circadian Rhythm; Clinical Trials as Topic; Diuretics; Double-Blind Met

1987
[Modification of resting and effort hemodynamics in essential arterial hypertension using antihypertensive agents].
    Deutsche medizinische Wochenschrift (1946), 1987, Oct-09, Volume: 112, Issue:41

    Topics: Acebutolol; Antihypertensive Agents; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged;

1987
Efficacy of a low fixed-dose combination of penbutolol with piretanide in the treatment of mild to moderate hypertension: a double-blind study against placebo.
    Pharmatherapeutica, 1986, Volume: 4, Issue:9

    Topics: Adult; Circadian Rhythm; Diuretics; Double-Blind Method; Drug Combinations; Exercise Test; Female; H

1986
Piretanide, a potassium stable diuretic, in the treatment of essential hypertension: a double-blind comparison of two formulations.
    The Journal of international medical research, 1985, Volume: 13, Issue:1

    Topics: Adult; Aged; Blood Pressure; Capsules; Clinical Trials as Topic; Delayed-Action Preparations; Diuret

1985
Piretanide for hypertension.
    Drug and therapeutics bulletin, 1985, Jun-03, Volume: 23, Issue:11

    Topics: Clinical Trials as Topic; Diuretics; Humans; Hypertension; Magnesium; Potassium; Sulfonamides

1985
Efficacy of penbutolol and a combination of a low dose of penbutolol with piretanide in the treatment of mild to moderate hypertension.
    Pharmatherapeutica, 1985, Volume: 4, Issue:4

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combinatio

1985
Single and divided daily dose piretanide in the treatment of uncomplicated essential hypertension: a double-blind comparison with a combination of hydrochlorothiazide and amiloride.
    European journal of clinical pharmacology, 1985, Volume: 29, Issue:3

    Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Fe

1985
Efficacy of penbutolol + piretanide combinations in the treatment of arterial hypertension.
    Drugs under experimental and clinical research, 1985, Volume: 11, Issue:10

    Topics: Adult; Blood Chemical Analysis; Blood Pressure; Body Weight; Clinical Trials as Topic; Diuretics; Dr

1985

Other Studies

14 other studies available for piretanide and Hypertension

ArticleYear
[Study report: Hypertension therapy with organ protection. Piretanid and Ramipril: advantages with fixed combination].
    Fortschritte der Medizin. Supplement : die Kongressinformation fur die Praxis, 1994, Volume: 164

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diuretics; Humans; Hypertension;

1994
Intracellular electrolytes during antihypertensive treatment with a loop diuretic.
    Journal of hypertension, 1984, Volume: 2, Issue:4

    Topics: Adult; Aged; Diuretics; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Potassium; So

1984
Intracellular calcium in essential hypertension. A parameter for assessing effective antihypertensive treatment.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:3

    Topics: Adult; Aged; Animals; Blood Pressure; Blood Volume; Calcium; Diuretics; Drug Evaluation; Drug Evalua

1984
[Evaluation of the antihypertensive effect of the new saluretic drug, piretanide].
    La Clinica terapeutica, 1982, Jul-15, Volume: 102, Issue:1

    Topics: Adult; Diuretics; Electrolytes; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Sulfo

1982
Piretanide in the treatment of hypertension. Effects on arterial blood pressure and several blood variables.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1981, Dec-12, Volume: 60, Issue:24

    Topics: Adult; Aged; Blood Pressure; Delayed-Action Preparations; Diuretics; Drug Evaluation; Electrolytes;

1981
[Cytolytic hepatic lesion associated with the ingestion of piretanide].
    Gastroenterologie clinique et biologique, 1995, Volume: 19, Issue:4

    Topics: Aged; Chemical and Drug Induced Liver Injury; Diuretics; Female; Humans; Hypertension; Liver Functio

1995
Pharmacological evaluation of hydroxypropylcellulose-ethylcellulose microcapsules containing piretanide.
    Journal of pharmacobio-dynamics, 1990, Volume: 13, Issue:1

    Topics: Administration, Oral; Aldosterone; Animals; Blood Pressure; Body Weight; Cellulose; Diuretics; Drug

1990
Loop diuretics combined with an ACE inhibitor for treatment of hypertension: a study with furosemide, piretanide, and ramipril in spontaneously hypertensive rats.
    Journal of cardiovascular pharmacology, 1989, Volume: 13 Suppl 3

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Bridged

1989
Na+-Li+ countertransport and electrolyte composition in erythrocytes of patients with essential hypertension before and after antihypertensive treatment.
    Klinische Wochenschrift, 1986, Oct-31, Volume: 64, Issue:21

    Topics: Adult; Diuretics; Erythrocytes; Female; Humans; Hypertension; Lithium; Male; Middle Aged; Sodium; Su

1986
Effects of a new diuretic piretanide on glucose tolerance, insulin secretion and 125I-insulin binding.
    European journal of clinical pharmacology, 1985, Volume: 27, Issue:6

    Topics: Adult; Blood Glucose; C-Peptide; Diuretics; Glucagon; Glucose Tolerance Test; Humans; Hypertension;

1985
Effects of piretanide on potassium balance in hypertension.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1985, Feb-09, Volume: 67, Issue:6

    Topics: Adult; Aged; Diuretics; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Sulfonamides

1985
Acute and chronic effects of the loop diuretic, piretanide, on baroreflex set point and sensitivity in hypertensive man.
    Journal of hypertension, 1985, Volume: 3, Issue:5

    Topics: Adult; Blood Pressure; Diuretics; Drug Evaluation; Drug Resistance; Female; Heart Rate; Humans; Hype

1985
Na+-K+ cotransport and hypertension. Effect of piretanide and hydrochlorothiazide on red blood cell sodium concentration in acutely salt-loaded hypertensive and normotensive rats.
    Clinical and experimental hypertension. Part A, Theory and practice, 1985, Volume: 7, Issue:10

    Topics: Animals; Biological Transport; Diuretics; Erythrocytes; Hydrochlorothiazide; Hypertension; Male; Pot

1985
The effects of piretanide capsules on blood pressure during ergometric and isometric work loads in patients with mild to moderate essential hypertension.
    Pharmatherapeutica, 1985, Volume: 4, Issue:6

    Topics: Adult; Aged; Blood Glucose; Blood Pressure; Capsules; Cholesterol; Creatinine; Diuretics; Female; Hu

1985