cgp 12177 has been researched along with Hypertension in 10 studies
CGP 12177 : A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of the chronic administration of bopindolol on the binding characteristics of [3H]CGP12177 and [3H]prazosin to cardiac alpha 1H-, alpha 1L-, beta 1- and beta 2-adrenoceptor subtypes of spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY) were compared with those of two other beta-blockers, atenolol and propranolol." | 1.29 | Effects of chronic administration of bopindolol on the binding characteristics of cardiac alpha 1H-, alpha 1L-, beta 1- and beta 2-adrenoceptor subtypes in cardiac muscles of spontaneously hypertensive rats (SHR). ( Hattori, K; Hosohata, Y; Maruyama, K; Nagatomo, T; Ohnuki, T; Sasaki, K; Suzuki, J; Watanabe, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Holopherne, D | 1 |
| Mallem, MY | 2 |
| Le Strat, E | 1 |
| Belin de Chantemèle, EJ | 1 |
| Gogny, M | 2 |
| Henrion, D | 1 |
| Noireaud, J | 1 |
| Desfontis, JC | 2 |
| Toumaniantz, G | 1 |
| Serpillon, S | 1 |
| Gautier, F | 1 |
| Gauthier, C | 1 |
| Frazier, EP | 1 |
| Schneider, T | 1 |
| Michel, MC | 1 |
| Zavecz, JH | 1 |
| Battarbee, HD | 1 |
| O'Donnell, JM | 1 |
| Blankesteijn, WM | 1 |
| Graafsma, SJ | 1 |
| Thien, T | 1 |
| Hosohata, Y | 1 |
| Sasaki, K | 1 |
| Maruyama, K | 1 |
| Ohnuki, T | 1 |
| Hattori, K | 1 |
| Suzuki, J | 1 |
| Watanabe, K | 1 |
| Nagatomo, T | 1 |
| Atrakchi, A | 1 |
| Carlsen, RC | 1 |
| Gray, SD | 1 |
| Michel, A | 1 |
| Hance, AJ | 1 |
| Matsumori, Y | 1 |
| Ohyanagi, M | 1 |
| Kawamoto, H | 1 |
| Shibata, R | 1 |
| Iwasaki, T | 1 |
| Limas, CJ | 1 |
| Limas, C | 1 |
| Feldman, RD | 1 |
| Lawton, WJ | 1 |
| McArdle, WL | 1 |
10 other studies available for cgp 12177 and Hypertension
| Article | Year |
|---|---|
CGP12177-induced haemodynamic and vascular effects in normotensive and hypertensive rats.
Topics: Adrenergic beta-Agonists; Animals; Dose-Response Relationship, Drug; Femoral Artery; Heart Rate; Hyp | 2008 |
Impairment of the low-affinity state beta1-adrenoceptor-induced relaxation in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Enzyme Inhi | 2004 |
Effects of gender, age and hypertension on beta-adrenergic receptor function in rat urinary bladder.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Age Factors; Animals; Ethanolamines; | 2006 |
Cardiac beta-adrenoceptor-effector coupling in portal vein-stenosed rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Constriction; Cyclic | 1995 |
Comments on the study by Bono et al.
Topics: Adrenergic beta-Antagonists; Humans; Hypertension; Lymphocytes; Propanolamines; Receptors, Adrenergi | 1996 |
Effects of chronic administration of bopindolol on the binding characteristics of cardiac alpha 1H-, alpha 1L-, beta 1- and beta 2-adrenoceptor subtypes in cardiac muscles of spontaneously hypertensive rats (SHR).
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Hypertension; In Vitro Techniques; Membranes; Myocar | 1996 |
Beta-receptor properties in soleus muscles from spontaneously hypertensive rats.
Topics: Animals; Cyclic AMP; Hindlimb; Hypertension; In Vitro Techniques; Male; Muscles; Osmolar Concentrati | 1989 |
Intracellular distribution of cardiac beta-adrenoceptors in SHR and WKY.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aging; Animals; Heart; Hypertension; In Vitro Techni | 1989 |
Altered intracellular adrenoceptor distribution in myocardium of spontaneously hypertensive rats.
Topics: Adrenergic beta-Agonists; Animals; Cardiomegaly; Cell Membrane; Cytosol; Dihydroalprenolol; Hyperten | 1987 |
Low sodium diet corrects the defect in lymphocyte beta-adrenergic responsiveness in hypertensive subjects.
Topics: Adenylyl Cyclases; Adult; Diet, Sodium-Restricted; Enzyme Activation; Humans; Hypertension; Lymphocy | 1987 |