gamma-aminobutyric acid has been researched along with Hypertension in 112 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Awake rats were subjected to phenylephrine- (PE-) induced hypertension (N=5) or received saline (N=5)." | 7.72 | Fos expression by glutamatergic neurons of the solitary tract nucleus after phenylephrine-induced hypertension in rats. ( Guyenet, PG; Sevigny, CP; Stornetta, RL; Wang, H; Weston, M, 2003) |
| " Adult male Sprague-Dawley rats placed on a pyridoxine-deficient diet for 8 weeks showed significant hypertension compared with pyridoxine-supplemented controls." | 7.67 | Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988) |
| "Hypertension was associated with sympathetic stimulation." | 5.27 | Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988) |
| "Treatment of pyridoxine-deficient rats with a single dose of pyridoxine (10 mg/kg body weight) reversed the blood pressure to normal levels within 24 hours, with concomitant restorations of hypothalamic serotonin and gamma-aminobutyric acid as well as the return of plasma norepinephrine and epinephrine to normal levels." | 5.27 | Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988) |
| " Pregabalin seems to provide clinically benefit to patients with fibromyalgia." | 4.85 | [Innovations in ambulatory care]. ( Bodenmann, P; Chapuis, T; Cornuz, J; de Bosset, V; Jaunin-Stalder, N; Marguerat, I; Nanchen, D; Pasche, O, 2009) |
| " The purpose of this study was to evaluate the effects of Gamma-aminobutyric acid (GABA) tea on hypertension-induced cardiac apoptotic pathways in spontaneously hypertensive rats (SHR)." | 3.88 | GABA tea attenuates cardiac apoptosis in spontaneously hypertensive rats (SHR) by enhancing PI3K/Akt-mediated survival pathway and suppressing Bax/Bak dependent apoptotic pathway. ( Chang, RL; Chen, BC; Chen, RJ; Huang, CY; Hung, MY; Lin, KH; Pandey, S; Viswanadha, VP; Wang, HF; Yeh, LJ, 2018) |
| " The case presentation illustrates the role of pregabalin in successful medical management of this chronic pain disorder, as well as the management of common psychiatric morbidities associated with this condition." | 3.74 | Pregabalin-induced remission in a 62-year-old woman with a 20-year history of vulvodynia. ( Jerome, L, 2007) |
| " Awake rats were subjected to phenylephrine- (PE-) induced hypertension (N=5) or received saline (N=5)." | 3.72 | Fos expression by glutamatergic neurons of the solitary tract nucleus after phenylephrine-induced hypertension in rats. ( Guyenet, PG; Sevigny, CP; Stornetta, RL; Wang, H; Weston, M, 2003) |
| "In situ expression of c-fos observed in response to phenylephrine (PE)-induced hypertension provided a basis for characterizing the organization and neurotransmitter specificity of neurons at nodal points of medullary baroreflex circuitry." | 3.70 | Organization and transmitter specificity of medullary neurons activated by sustained hypertension: implications for understanding baroreceptor reflex circuitry. ( Chan, RK; Sawchenko, PE, 1998) |
| "To determine whether chronic central gamma-aminobutyric acid (GABA) stimulation would attenuate development of hypertension, tail-cuff systolic pressures were measured in male spontaneously hypertensive rats (SHR) treated with either an inhibitor of GABA breakdown (valproate, VPA), or a GABA-receptor agonist (muscimol)." | 3.68 | Chronic central GABAergic stimulation attenuates hypothalamic hyperactivity and development of spontaneous hypertension in rats. ( Hayashi, J; Kawasaki, S; Nakagawa, M; Nakata, T; Oguro, M; Sasaki, S; Takeda, K, 1990) |
| "The aim was to assess whether Gamma-aminobutyric acid (GABA) neurone activities in the central nervous system, especially in the hypothalamus and medulla oblangata, are altered in hypertension." | 3.68 | Decreased hypothalamic and medullary GABA turnover in spontaneously hypertensive rats. ( Hirata, M; Kuwabara, T; Nakata, T; Sasaki, S; Takenaka, K; Takesako, T; Tanabe, S; Tanaka, M; Yoneda, Y; Yoshitomi, T, 1992) |
| "To elucidate the role of the central gamma-aminobutyric acid (GABA) system in the maintenance of deoxycorticosterone (DOCA)NaCl hypertension, the responses of mean arterial pressure (MAP), plasma norepinephrine (NE), and epinephrine (EP) to intracerebroventricular (ICV) administration of muscimol, a GABA agonist, and the responses of MAP to bicuculline, a GABA antagonist, and to clonidine, an alpha 2-adrenoceptor agonist known to lower blood pressure by inhibiting sympathetic tone, were examined in conscious, unrestrained 4 week DOCA/NaCl hypertensive rats and age-matched uninephrectomized control rats." | 3.67 | Enhanced depressor effect of muscimol in the DOCA/NaCl hypertensive rat: evidence for altered GABAergic activity in brain. ( Dawson, R; Nagahama, S; Oparil, S, 1985) |
| "gamma-Aminobutyric acid (GABA) has been implicated in the development of hypertension and in the regulation of blood pressure." | 3.67 | The GABA/benzodiazepine receptor complex in the nervous system of a hypertensive strain of rat. ( Head, RA; Tunnicliff, G; Welborn, KL, 1984) |
| " Intraperitoneal injection of valproic acid (50-100 mg/Kg/die) for 6 weeks significantly reduced the development of DOCA-salt hypertension in rats." | 3.67 | Increased cardiovascular responsiveness to GABAergic stimulation in DOCA-salt hypertensive rats. ( Caputi, AP; Costa, G; Di Giorgio, RM; Magrì, V; Quattrone, G; Squadrito, F; Trimarchi, GR, 1984) |
| " Gamma-Aminobutyric acid at 50 nmol/100 nl produced bradycardia and a fall in arterial pressure when injected into both the nucleus ambiguus and C1 area." | 3.67 | Role of the nucleus ambiguus in the regulation of heart rate and arterial pressure. ( Brody, MJ; Machado, BH, 1988) |
| " Adult male Sprague-Dawley rats placed on a pyridoxine-deficient diet for 8 weeks showed significant hypertension compared with pyridoxine-supplemented controls." | 3.67 | Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988) |
| "In conscious rats with normal arterial blood pressure or with spontaneous or DOC induced hypertension, effects of drugs increasing (cycloserine, ethanolamine-o-sulphate, piracetam, chlordesmethyldiazepam) or depressing (bicuculline, Ro 15-1788, PK 11195) GABAergic reactivity were evaluated on the arterial hypotension and sinus bradycardia induced by clonidine." | 3.67 | Participation of GABAergic mechanisms in the hypotensive and bradycardic effects of clonidine: experimental study in conscious normotensive and hypertensive rats. ( Cazzola, M; Filippelli, W; Marmo, E; Marrazzo, R; Rossi, F; Russo, S; Vacca, C, 1987) |
| " Additionally, present knowledge of bioavailability and in-vivo actions of the peptides in fermented milk are discussed." | 2.45 | Does fermented milk possess antihypertensive effect in humans? ( Ibsen, H; Jensen, LT; Usinger, L, 2009) |
| "Most forms of hypertension are associated with a wide variety of functional changes in the hypothalamus." | 2.41 | The hypothalamus and hypertension. ( de Wardener, HE, 2001) |
| "Hypertension is one of the most critical risk factors accompanying cardiovascular diseases." | 1.42 | Field trial of GABA-fortified rice plants and oral administration of milled rice in spontaneously hypertensive rats. ( Akama, K; Kawakami, K; Kowaka, E; Shimajiri, Y; Tongu, M, 2015) |
| "Hypertension is considered an independent risk factor for cardiovascular mortality in diabetic patients." | 1.42 | Role of GABAB receptor and L-Arg in GABA-induced vasorelaxation in non-diabetic and streptozotocin-induced diabetic rat vessels. ( Farsi, L; Keshavarz, M; Kharazmi, F; Rezaei, S; Soltani, N, 2015) |
| "Gamma-aminobutyric acid (GABA) is an important neurotransmitter, but recent reports have revealed the expression of GABAergic components in peripheral, non-neural tissues." | 1.40 | Characteristic expressions of GABA receptors and GABA producing/transporting molecules in rat kidney. ( Abe, A; Kimura, J; Sanada, H; Suzuki, Y; Takano, K; Watanabe, T; Yatabe, J; Yatabe, MS, 2014) |
| "Hypertension is considered an independent risk factor for cardiovascular mortality in diabetic patients." | 1.39 | GABA-induced vasorelaxation mediated by nitric oxide and GABAA receptor in non diabetic and streptozotocin-induced diabetic rat vessels. ( Bahrami, A; Farsi, L; Kamran, M; Keshavarz, M; Soltani, N, 2013) |
| "Hypertension is a major risk factor for coronary artery disease, stroke, and kidney failure." | 1.38 | NKCC1 upregulation disrupts chloride homeostasis in the hypothalamus and increases neuronal activity-sympathetic drive in hypertension. ( Byun, HS; Li, DP; Li, L; Pan, HL; Ye, ZY, 2012) |
| "A hallmark of hypertension is an increase in arterial myocyte voltage-dependent Ca2+ (CaV1." | 1.38 | Transcriptional upregulation of α2δ-1 elevates arterial smooth muscle cell voltage-dependent Ca2+ channel surface expression and cerebrovascular constriction in genetic hypertension. ( Bannister, JP; Bulley, S; Jaggar, JH; Luzny, P; Narayanan, D; Pachuau, J; Thomas-Gatewood, C, 2012) |
| " In a chronic administration study, SHR were fed diets containing one of the tomato cultivars for 4 weeks." | 1.36 | Antihypertensive effect of a gamma-aminobutyric acid rich tomato cultivar 'DG03-9' in spontaneously hypertensive rats. ( Ezura, H; Fujii, T; Fukuda, N; Inai, S; Izumi, T; Konishi, C; Matsukura, C; Obata, A; Sano, A; Toyoshi, T; Yoshimura, M, 2010) |
| "The patient displayed unique withdrawal symptoms after the taper of gabapentin." | 1.33 | Gabapentin withdrawal syndrome in the presence of a taper. ( Hranicky, D; Jacob, Nj; Lark, T; Tran, KT, 2005) |
| " Past reports have suggested that some withdrawal symptoms can present after 1-2 days upon abrupt discontinuation of gabapentin after chronic use within young to middle-aged patients." | 1.33 | Gabapentin withdrawal syndrome in the presence of a taper. ( Hranicky, D; Jacob, Nj; Lark, T; Tran, KT, 2005) |
| "Past reports have suggested that some withdrawal symptoms can present after 1-2 days upon abrupt discontinuation of gabapentin after chronic use within young to middle-aged patients." | 1.33 | Gabapentin withdrawal syndrome in the presence of a taper. ( Hranicky, D; Jacob, Nj; Lark, T; Tran, KT, 2005) |
| " In contrast, chronic administration of dihydralazine had no influence on GABA synthesis rate." | 1.29 | Enhancement of GABAergic system activity by metoprolol in spontaneously hypertensive rats. ( Czyzewska-Szafran, H; Jastrzebski, Z; Remiszewska, M; Wutkiewicz, M, 1993) |
| " Chronic administration of clonidine, 10 micrograms." | 1.28 | Effect of clonidine on blood pressure and GABAergic mechanisms in spontaneously hypertensive rats. ( Czyzewska-Szafran, H; Jastrzebski, Z; Remiszewska, M; Wutkiewicz, M, 1991) |
| "Treatment of pyridoxine-deficient rats with a single dose of pyridoxine (10 mg/kg body weight) reversed the blood pressure to normal levels within 24 hours, with concomitant restorations of hypothalamic serotonin and gamma-aminobutyric acid as well as the return of plasma norepinephrine and epinephrine to normal levels." | 1.27 | Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988) |
| "Hypertension was associated with sympathetic stimulation." | 1.27 | Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988) |
| "gamma-Aminobutyric acid (GABA) has been implicated in the development of hypertension and in the regulation of blood pressure." | 1.27 | The GABA/benzodiazepine receptor complex in the nervous system of a hypertensive strain of rat. ( Head, RA; Tunnicliff, G; Welborn, KL, 1984) |
| "Clonidine was administered orally by gastric gavage (0." | 1.27 | Participation of GABAergic mechanisms in the hypotensive and bradycardic effects of clonidine: experimental study in conscious normotensive and hypertensive rats. ( Cazzola, M; Filippelli, W; Marmo, E; Marrazzo, R; Rossi, F; Russo, S; Vacca, C, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (24.11) | 18.7374 |
| 1990's | 18 (16.07) | 18.2507 |
| 2000's | 25 (22.32) | 29.6817 |
| 2010's | 35 (31.25) | 24.3611 |
| 2020's | 7 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Agrud, A | 1 |
| Subburaju, S | 1 |
| Goel, P | 1 |
| Ren, J | 1 |
| Kumar, AS | 1 |
| Caldarone, BJ | 1 |
| Dai, W | 1 |
| Chavez, J | 1 |
| Fukumura, D | 1 |
| Jain, RK | 1 |
| Kloner, RA | 1 |
| Vasudevan, A | 1 |
| Strauss-Kruger, M | 1 |
| van Zyl, T | 1 |
| Pieters, M | 1 |
| Kruger, R | 1 |
| Mokwatsi, G | 1 |
| Gafane-Matemane, L | 1 |
| Mbongwa, H | 1 |
| Jacobs, A | 1 |
| Schutte, AE | 1 |
| Louw, R | 1 |
| Mels, C | 1 |
| Liska, DJ | 3 |
| Dioum, E | 3 |
| Chu, Y | 3 |
| Mah, E | 3 |
| Wang, FZ | 1 |
| Qian, P | 1 |
| Liu, MY | 1 |
| Ding, L | 1 |
| Wang, HY | 1 |
| Wang, Q | 1 |
| Ding, ZY | 1 |
| Jin, FY | 1 |
| Li, RG | 1 |
| Zhou, YB | 1 |
| Martínez, LA | 1 |
| Cifuentes, F | 1 |
| Morales, MA | 1 |
| Zareian, M | 1 |
| Oskoueian, E | 1 |
| Majdinasab, M | 1 |
| Forghani, B | 1 |
| Gouse, BM | 1 |
| Spears, WE | 1 |
| Nieves Archibald, A | 1 |
| Montalvo, C | 1 |
| Chan, JCY | 1 |
| Waddell, TK | 1 |
| Yasufuku, K | 1 |
| Keshavjee, S | 1 |
| Donahoe, LL | 1 |
| Levenbrown, Y | 1 |
| Hossain, MJ | 1 |
| Keith, JP | 1 |
| Burr, K | 1 |
| Hesek, A | 1 |
| Shaffer, TH | 1 |
| Yao, LL | 1 |
| Cao, JR | 1 |
| Lyu, CJ | 1 |
| Fan, FF | 1 |
| Wang, HP | 1 |
| Cao, HW | 1 |
| Huang, J | 1 |
| Mei, LH | 1 |
| He, P | 1 |
| Li, Y | 1 |
| Zhang, R | 1 |
| Ren, M | 1 |
| Liu, H | 1 |
| Yang, M | 1 |
| Liu, X | 1 |
| Wang, Z | 1 |
| Xu, C | 1 |
| Guan, J | 1 |
| Wei, B | 1 |
| Liu, Y | 1 |
| Swinkels, BM | 1 |
| Ten Berg, JM | 1 |
| Kelder, JC | 1 |
| Vermeulen, FE | 1 |
| van Boven, WJ | 1 |
| de Mol, BA | 1 |
| Huang, K | 1 |
| Yang, X | 1 |
| Ma, Y | 1 |
| Sun, G | 1 |
| Nitin, N | 1 |
| Wickramasinghe, A | 1 |
| Xiao, Y | 1 |
| Kobayashi, N | 1 |
| Wang, S | 1 |
| Scherpelz, KP | 1 |
| Yamazaki, T | 1 |
| Meredith, SC | 1 |
| Ishii, Y | 1 |
| Phoonsawat, K | 1 |
| Khachornsakkul, K | 1 |
| Ratnarathorn, N | 1 |
| Henry, CS | 1 |
| Dungchai, W | 1 |
| Zareena, B | 1 |
| Khadim, A | 1 |
| Jeelani, SUY | 1 |
| Hussain, S | 1 |
| Ali, A | 1 |
| Musharraf, SG | 1 |
| Zhuo, X | 1 |
| Jiang, W | 1 |
| Qian, G | 1 |
| Chen, J | 2 |
| Yu, T | 1 |
| Luo, L | 1 |
| Lu, L | 1 |
| Chen, Y | 1 |
| Yin, S | 1 |
| Hong, NJ | 1 |
| Gonzalez-Vicente, A | 1 |
| Saez, F | 1 |
| Garvin, JL | 1 |
| Hede, KTC | 1 |
| Christensen, BB | 1 |
| Olesen, ML | 1 |
| Thomsen, JS | 1 |
| Foldager, CB | 1 |
| Toh, WS | 1 |
| Lim, SK | 1 |
| Lind, MC | 1 |
| Woods, LM | 1 |
| Connelly, CD | 1 |
| Doğan, MF | 1 |
| Başak Türkmen, N | 1 |
| Taşlıdere, A | 1 |
| Şahin, Y | 1 |
| Çiftçi, O | 1 |
| Hsu, CH | 1 |
| Yu, SM | 1 |
| Lau, SC | 1 |
| Chen, YL | 1 |
| Pei, D | 1 |
| Liu, IC | 1 |
| Shen, Z | 1 |
| Weng, C | 1 |
| Zhang, Z | 1 |
| Wang, X | 1 |
| Yang, K | 1 |
| Kakall, ZM | 1 |
| Pilowsky, PM | 1 |
| Farnham, MMJ | 1 |
| Chen, BC | 1 |
| Hung, MY | 1 |
| Wang, HF | 1 |
| Yeh, LJ | 1 |
| Pandey, S | 1 |
| Chen, RJ | 1 |
| Chang, RL | 1 |
| Viswanadha, VP | 1 |
| Lin, KH | 1 |
| Huang, CY | 2 |
| Kamran, M | 1 |
| Bahrami, A | 1 |
| Soltani, N | 2 |
| Keshavarz, M | 2 |
| Farsi, L | 2 |
| Kawabe, T | 1 |
| Kawabe, K | 1 |
| Sapru, HN | 1 |
| Rossi, NF | 1 |
| Chen, H | 1 |
| Maliszewska-Scislo, M | 1 |
| Kang, YM | 2 |
| Zhang, DM | 1 |
| Yu, XJ | 2 |
| Yang, Q | 1 |
| Qi, J | 2 |
| Su, Q | 1 |
| Suo, YP | 2 |
| Yue, LY | 1 |
| Zhu, GQ | 2 |
| Qin, DN | 2 |
| Jia, LL | 1 |
| Wang, FX | 1 |
| Li, HB | 1 |
| Zhang, Y | 1 |
| Tian, ZJ | 1 |
| Zhu, Z | 2 |
| Miyoshi, H | 1 |
| Oishi, Y | 1 |
| Mizuguchi, Y | 1 |
| Iuchi, A | 1 |
| Nagase, N | 1 |
| Ara, N | 1 |
| Oki, T | 1 |
| Takano, K | 1 |
| Yatabe, MS | 1 |
| Abe, A | 2 |
| Suzuki, Y | 1 |
| Sanada, H | 1 |
| Watanabe, T | 1 |
| Kimura, J | 1 |
| Yatabe, J | 1 |
| Zhang, H | 1 |
| Pu, Y | 1 |
| Tong, W | 1 |
| Cui, Y | 1 |
| Sun, F | 1 |
| Zheng, Z | 1 |
| Li, Q | 1 |
| Yang, T | 1 |
| Meng, C | 1 |
| Lu, Z | 1 |
| Li, L | 2 |
| Yan, Z | 1 |
| Liu, D | 1 |
| Kowaka, E | 1 |
| Shimajiri, Y | 1 |
| Kawakami, K | 1 |
| Tongu, M | 1 |
| Akama, K | 1 |
| Chang, VH | 1 |
| Chiu, TH | 1 |
| Fu, SC | 1 |
| Duan, XC | 1 |
| Liu, SY | 1 |
| Guo, R | 1 |
| Xiao, L | 1 |
| Xue, HM | 1 |
| Guo, Q | 1 |
| Jin, S | 1 |
| Wu, YM | 1 |
| Kharazmi, F | 1 |
| Rezaei, S | 1 |
| Hieda, K | 1 |
| Sunagawa, Y | 1 |
| Katanasaka, Y | 1 |
| Hasegawa, K | 1 |
| Morimoto, T | 1 |
| Bala, I | 1 |
| Bharti, N | 1 |
| Ramesh, NP | 1 |
| Kitajima, S | 1 |
| Iwata, Y | 1 |
| Furuichi, K | 1 |
| Sagara, A | 1 |
| Shinozaki, Y | 1 |
| Toyama, T | 1 |
| Sakai, N | 1 |
| Shimizu, M | 1 |
| Sakurai, T | 1 |
| Kaneko, S | 1 |
| Wada, T | 1 |
| Becerra-Tomás, N | 1 |
| Guasch-Ferré, M | 1 |
| Quilez, J | 1 |
| Merino, J | 1 |
| Ferré, R | 1 |
| Díaz-López, A | 1 |
| Bulló, M | 1 |
| Hernández-Alonso, P | 1 |
| Palau-Galindo, A | 1 |
| Salas-Salvadó, J | 1 |
| Smulevich, AB | 1 |
| Volel, BA | 1 |
| Ternovaya, ES | 1 |
| Nikitina, YM | 1 |
| Duma, SN | 1 |
| Shcherbakova, LV | 1 |
| Bodenmann, P | 1 |
| Pasche, O | 1 |
| Nanchen, D | 1 |
| Jaunin-Stalder, N | 1 |
| Marguerat, I | 1 |
| Chapuis, T | 1 |
| de Bosset, V | 1 |
| Cornuz, J | 1 |
| Usinger, L | 1 |
| Ibsen, H | 1 |
| Jensen, LT | 1 |
| Shimada, M | 1 |
| Hasegawa, T | 1 |
| Nishimura, C | 1 |
| Kan, H | 1 |
| Kanno, T | 1 |
| Nakamura, T | 1 |
| Matsubayashi, T | 1 |
| Zhang, W | 1 |
| Mifflin, S | 1 |
| Yoshimura, M | 2 |
| Toyoshi, T | 1 |
| Sano, A | 1 |
| Izumi, T | 1 |
| Fujii, T | 1 |
| Konishi, C | 1 |
| Inai, S | 1 |
| Matsukura, C | 1 |
| Fukuda, N | 1 |
| Ezura, H | 1 |
| Obata, A | 2 |
| Chen, CY | 1 |
| Bonham, AC | 1 |
| Zubcevic, J | 1 |
| Potts, JT | 1 |
| Liu, CF | 1 |
| Tung, YT | 1 |
| Wu, CL | 1 |
| Lee, BH | 1 |
| Hsu, WH | 1 |
| Pan, TM | 1 |
| Huber, DA | 1 |
| Schreihofer, AM | 1 |
| Mokrushin, AA | 1 |
| Pavlinova, LI | 1 |
| Madhugiri, VS | 1 |
| Roopesh Kumar, VR | 1 |
| Gopalakrishnan, MS | 1 |
| Shankar Ganesh, CV | 1 |
| Sudheer Kumar, G | 1 |
| Ye, ZY | 1 |
| Li, DP | 2 |
| Byun, HS | 1 |
| Pan, HL | 2 |
| Bannister, JP | 1 |
| Bulley, S | 1 |
| Narayanan, D | 1 |
| Thomas-Gatewood, C | 1 |
| Luzny, P | 1 |
| Pachuau, J | 1 |
| Jaggar, JH | 1 |
| Shinohara, K | 1 |
| Hirooka, Y | 1 |
| Kishi, T | 1 |
| Sunagawa, K | 1 |
| Lin, PP | 1 |
| Hsieh, YM | 1 |
| Kuo, WW | 1 |
| Lin, CC | 1 |
| Tsai, FJ | 1 |
| Tsai, CH | 1 |
| Tsai, CC | 1 |
| Kimura, M | 3 |
| Hayakawa, K | 3 |
| Sansawa, H | 2 |
| Kubo, T | 2 |
| Hagiwara, Y | 1 |
| Endo, S | 1 |
| Fukumori, R | 1 |
| Inoue, K | 1 |
| Shirai, T | 1 |
| Ochiai, H | 1 |
| Kasao, M | 1 |
| Buijs, RM | 1 |
| van Eden, CG | 1 |
| Goncharuk, VD | 1 |
| Kalsbeek, A | 1 |
| Weston, M | 1 |
| Wang, H | 1 |
| Stornetta, RL | 1 |
| Sevigny, CP | 1 |
| Guyenet, PG | 1 |
| Hsieh, PS | 1 |
| Tai, YH | 1 |
| TAKAHASHI, H | 2 |
| SUMI, M | 1 |
| KOSHINO, F | 1 |
| HIRAKI, K | 1 |
| IRINO, S | 1 |
| ASANO, T | 1 |
| YAMAMOTO, S | 1 |
| HARAOKA, T | 1 |
| HASHIMOTO, Y | 1 |
| Sved, AF | 2 |
| Sved, JC | 1 |
| Shizuka, F | 1 |
| Kido, Y | 1 |
| Nakazawa, T | 1 |
| Kitajima, H | 1 |
| Aizawa, C | 1 |
| Kayamura, H | 1 |
| Ichijo, N | 1 |
| Tran, KT | 1 |
| Hranicky, D | 1 |
| Lark, T | 1 |
| Jacob, Nj | 1 |
| Yamori, Y | 1 |
| Morato, M | 1 |
| Pinho, D | 1 |
| Sousa, T | 1 |
| Tavares, I | 1 |
| Albino-Teixeira, A | 1 |
| Jastrzebski, Z | 3 |
| Gorinstein, S | 1 |
| Czyzewska-Szafran, H | 3 |
| Leontowicz, H | 1 |
| Leontowicz, M | 1 |
| Trakhtenberg, S | 1 |
| Remiszewska, M | 3 |
| Yamakoshi, J | 1 |
| Fukuda, S | 1 |
| Satoh, T | 1 |
| Tsuji, R | 1 |
| Saito, M | 1 |
| Matsuyama, A | 1 |
| Kikuchi, M | 1 |
| Kawasaki, T | 1 |
| Shindo, M | 1 |
| Kasai, T | 1 |
| Kondo, Y | 1 |
| Jerome, L | 1 |
| Brennan, TJ | 2 |
| Haywood, JR | 2 |
| Ticku, MK | 2 |
| Tunnicliff, G | 1 |
| Welborn, KL | 1 |
| Head, RA | 1 |
| DeFeudis, FV | 1 |
| Gillis, RA | 1 |
| Yamada, KA | 1 |
| DiMicco, JA | 1 |
| Williford, DJ | 1 |
| Segal, SA | 1 |
| Hamosh, P | 1 |
| Norman, WP | 1 |
| Magrì, V | 1 |
| Trimarchi, GR | 1 |
| Quattrone, G | 1 |
| Squadrito, F | 1 |
| Di Giorgio, RM | 1 |
| Costa, G | 1 |
| Caputi, AP | 2 |
| Tuomisto, L | 1 |
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| Dietl, H | 1 |
| Waldmann, U | 1 |
| Philippu, A | 2 |
| Hwang, BH | 1 |
| Wu, JY | 1 |
| Rotiroti, D | 1 |
| Palella, B | 1 |
| Losi, E | 1 |
| Nistico, G | 1 |
| Roberts, E | 1 |
| Krause, DN | 1 |
| Roberts, KA | 1 |
| Wright, JW | 1 |
| Harding, JW | 1 |
| Abe, Y | 1 |
| Umemura, S | 1 |
| Sugimoto, K | 1 |
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| Yokoyama, N | 1 |
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| Iwai, J | 1 |
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| Wutkiewicz, M | 2 |
| Sessler, FM | 1 |
| Mah, EJ | 1 |
| Grady, SM | 1 |
| Momohara, M | 1 |
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| Suzuki, S | 1 |
| Tagawa, T | 1 |
| Shiramoto, M | 1 |
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| Kozuka, M | 1 |
| Iwata, N | 1 |
| Ichida, T | 2 |
| Sasaki, S | 5 |
| Takeda, K | 4 |
| Kuriyama, K | 2 |
| Nakagawa, M | 4 |
| Misu, Y | 2 |
| Goshima, Y | 1 |
| Yue, JL | 1 |
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| Chan, RK | 1 |
| Sawchenko, PE | 1 |
| Kramer, JM | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Vigiis 101 Lactic Acid Bacteria Powder on Body Weight and Body Fat in Overweight Participants: a Randomized, Double-blinded, Placebo-controlled Trial[NCT05869799] | 100 participants (Anticipated) | Interventional | 2023-05-01 | Recruiting | |||
| Functional Assessment in The Intestinal Flora Improvement[NCT04088474] | 36 participants (Actual) | Interventional | 2016-03-05 | Completed | |||
| Effects of Vigiis 101-LAB on Gut Health[NCT04046432] | 54 participants (Actual) | Interventional | 2017-03-27 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
19 reviews available for gamma-aminobutyric acid and Hypertension
| Article | Year |
|---|---|
Narrative Review on the Effects of Oat and Sprouted Oat Components on Blood Pressure.
Topics: Antihypertensive Agents; Avena; beta-Glucans; Blood Pressure; Cardiovascular Diseases; Dietary Fiber | 2022 |
Narrative Review on the Effects of Oat and Sprouted Oat Components on Blood Pressure.
Topics: Antihypertensive Agents; Avena; beta-Glucans; Blood Pressure; Cardiovascular Diseases; Dietary Fiber | 2022 |
Narrative Review on the Effects of Oat and Sprouted Oat Components on Blood Pressure.
Topics: Antihypertensive Agents; Avena; beta-Glucans; Blood Pressure; Cardiovascular Diseases; Dietary Fiber | 2022 |
Narrative Review on the Effects of Oat and Sprouted Oat Components on Blood Pressure.
Topics: Antihypertensive Agents; Avena; beta-Glucans; Blood Pressure; Cardiovascular Diseases; Dietary Fiber | 2022 |
Narrative Review on the Effects of Oat and Sprouted Oat Components on Blood Pressure.
Topics: Antihypertensive Agents; Avena; beta-Glucans; Blood Pressure; Cardiovascular Diseases; Dietary Fiber | 2022 |
Narrative Review on the Effects of Oat and Sprouted Oat Components on Blood Pressure.
Topics: Antihypertensive Agents; Avena; beta-Glucans; Blood Pressure; Cardiovascular Diseases; Dietary Fiber | 2022 |
Narrative Review on the Effects of Oat and Sprouted Oat Components on Blood Pressure.
Topics: Antihypertensive Agents; Avena; beta-Glucans; Blood Pressure; Cardiovascular Diseases; Dietary Fiber | 2022 |
Narrative Review on the Effects of Oat and Sprouted Oat Components on Blood Pressure.
Topics: Antihypertensive Agents; Avena; beta-Glucans; Blood Pressure; Cardiovascular Diseases; Dietary Fiber | 2022 |
Narrative Review on the Effects of Oat and Sprouted Oat Components on Blood Pressure.
Topics: Antihypertensive Agents; Avena; beta-Glucans; Blood Pressure; Cardiovascular Diseases; Dietary Fiber | 2022 |
Pharmacological effect of functional foods with a hypotensive action.
Topics: Acetic Acid; Animals; Antihypertensive Agents; Catechin; Dioxoles; Diterpenes, Kaurane; Docosahexaen | 2015 |
[Innovations in ambulatory care].
Topics: Acute Disease; Age Factors; Aged, 80 and over; Algorithms; Ambulatory Care; Analgesics; Angiotensin- | 2009 |
Does fermented milk possess antihypertensive effect in humans?
Topics: Antihypertensive Agents; Biological Availability; Blood Pressure; Clinical Trials as Topic; Cultured | 2009 |
Plasticity of GABAergic mechanisms within the nucleus of the solitary tract in hypertension.
Topics: Adaptation, Physiological; Animals; Baroreflex; Female; GABA Plasma Membrane Transport Proteins; gam | 2010 |
Postexercise hypotension: central mechanisms.
Topics: Animals; Baroreflex; Blood Pressure; Brain Stem; Exercise; gamma-Aminobutyric Acid; Humans; Hyperten | 2010 |
The biological clock tunes the organs of the body: timing by hormones and the autonomic nervous system.
Topics: Animals; Autonomic Nervous System; Behavior; Biological Clocks; Circadian Rhythm; Depression; gamma- | 2003 |
Plasticity of GABA function in the nucleus tractus solitarius in hypertension.
Topics: Animals; gamma-Aminobutyric Acid; Hypertension; Neuronal Plasticity; Solitary Nucleus | 2003 |
gamma-Aminobutyric acid and cardiovascular function.
Topics: Animals; Atropine; Baclofen; Blood Pressure; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; | 1983 |
Benzodiazepine-GABA receptor-ionophore complex. Current concepts.
Topics: Animals; Benzodiazepines; Ethanol; gamma-Aminobutyric Acid; Humans; Hypertension; Ionophores; Ligand | 1983 |
gamma-Aminobutyric acid system in cardiovascular and cerebrovascular function.
Topics: 4-Aminobutyrate Transaminase; Animals; Antihypertensive Agents; Blood Pressure; Brain; Cardiovascula | 1982 |
Hypothalamus, hypertension, and exercise.
Topics: Animals; Cardiovascular Physiological Phenomena; Disease Models, Animal; gamma-Aminobutyric Acid; Hy | 2000 |
The hypothalamus and hypertension.
Topics: Acetylcholine; Angiotensins; Animals; Blood Pressure; Brain; Catecholamines; Enzyme Inhibitors; gamm | 2001 |
Amino acid neurotransmitters in the central control of blood pressure and in experimental hypertension.
Topics: Amino Acids; Animals; Blood Pressure; Central Nervous System; gamma-Aminobutyric Acid; Hypertension; | 1992 |
Bulbospinal substance P and sympathetic regulation of the cardiovascular system: a review.
Topics: Animals; Autonomic Fibers, Preganglionic; Bicuculline; Brain Mapping; Cardiovascular Physiological P | 1985 |
Neurohumoral mechanisms of sodium-dependent hypertension.
Topics: Animals; Arginine Vasopressin; Diet, Sodium-Restricted; gamma-Aminobutyric Acid; Humans; Hypertensio | 1985 |
[Neural mechanisms controlling and regulating the arterial pressure].
Topics: Adrenal Glands; Animals; Blood Pressure; Brain; Catecholamines; gamma-Aminobutyric Acid; Humans; Hyp | 1985 |
[GABA and central regulation of cardiovascular function].
Topics: Angiotensin II; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Baclofen; Benzodiazepines; Bi | 1985 |
Brain neurotransmitters and the development and maintenance of experimental hypertension.
Topics: Acetylcholine; Animals; Brain; Dopamine; Epinephrine; gamma-Aminobutyric Acid; Histamine; Hypertensi | 1986 |
6 trials available for gamma-aminobutyric acid and Hypertension
| Article | Year |
|---|---|
Effect of gabapentin pretreatment on the hemodynamic response to laryngoscopy and tracheal intubation in treated hypertensive patients.
Topics: Adult; Amines; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobuty | 2015 |
Effect of Functional Bread Rich in Potassium, γ-Aminobutyric Acid and Angiotensin-Converting Enzyme Inhibitors on Blood Pressure, Glucose Metabolism and Endothelial Function: A Double-blind Randomized Crossover Clinical Trial.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Blood Glucose; Blood | 2015 |
[Pantogam activ (D-, L-hopantenic acid) in the treatment of cognitive and anxiety disorders in patients with arterial hypertension].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Anxiety Disorders; Blood Pressure Monitoring, Ambu | 2015 |
[Diagnosis and treatment of psychogenic dizziness in patients with arterial hypertension].
Topics: Aged; Anxiety; Asthenia; Betahistine; Dizziness; Female; gamma-Aminobutyric Acid; Humans; Hypertensi | 2016 |
Anti-hypertensive effect of gamma-aminobutyric acid (GABA)-rich Chlorella on high-normal blood pressure and borderline hypertension in placebo-controlled double blind study.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Body Mass Index; Chlorella; Dose-Response Relationsh | 2009 |
Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antihypertensive Agents; Blood Pressure; Female; Fermentati | 2003 |
87 other studies available for gamma-aminobutyric acid and Hypertension
| Article | Year |
|---|---|
Gabrb3 endothelial cell-specific knockout mice display abnormal blood flow, hypertension, and behavioral dysfunction.
Topics: Animals; Endothelial Cells; gamma-Aminobutyric Acid; Hypertension; Mice; Mice, Knockout; Receptors, | 2022 |
Urinary metabolomics, dietary salt intake and blood pressure: the African-PREDICT study.
Topics: Adult; African People; Amino Acids; Blood Pressure; Cardiovascular Diseases; gamma-Aminobutyric Acid | 2023 |
Adrenomedullin in paraventricular nucleus attenuates adipose afferent reflex and sympathoexcitation via receptors mediated nitric oxide-gamma-aminobutyric acid A type receptor pathway in rats with obesity-related hypertension.
Topics: Adrenomedullin; Animals; Bicuculline; Blood Pressure; gamma-Aminobutyric Acid; Hypertension; Nitric | 2023 |
Ganglionic Long-Term Potentiation in Prehypertensive and Hypertensive Stages of Spontaneously Hypertensive Rats Depends on GABA Modulation.
Topics: Animals; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Hypertension; L | 2019 |
Production of GABA-enriched idli with ACE inhibitory and antioxidant properties using Aspergillus oryzae: the antihypertensive effects in spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aspergillus oryzae; Bloo | 2020 |
Catatonia in a hospitalized patient with COVID-19 and proposed immune-mediated mechanism.
Topics: Aged; Atrial Fibrillation; Basal Ganglia; Betacoronavirus; C-Reactive Protein; Catatonia; Coronaviru | 2020 |
Topics: Acetic Acid; Albumins; Alkaline Phosphatase; Alkaloids; Amyloid beta-Peptides; Analgesics, Opioid; A | 2021 |
Restless legs syndrome/Willis-Ekbom disease in type 2 diabetes as the initial manifestation of Parkinson's disease and major cardiovascular disease.
Topics: Aged; Amines; Analgesics; Anticonvulsants; Antihypertensive Agents; Antiparkinson Agents; Aspirin; B | 2017 |
Renal sympathetic denervation lowers arterial pressure in canines with obesity-induced hypertension by regulating GAD65 and AT
Topics: Angiotensin II; Animals; Blood Pressure; Dogs; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hyp | 2018 |
PACAP-(6-38) or kynurenate microinjections in the RVLM prevent the development of sympathetic long-term facilitation after acute intermittent hypoxia.
Topics: Acute Disease; Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Hypertension | 2018 |
GABA tea attenuates cardiac apoptosis in spontaneously hypertensive rats (SHR) by enhancing PI3K/Akt-mediated survival pathway and suppressing Bax/Bak dependent apoptotic pathway.
Topics: Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspase | 2018 |
GABA-induced vasorelaxation mediated by nitric oxide and GABAA receptor in non diabetic and streptozotocin-induced diabetic rat vessels.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endotheli | 2013 |
Tonic γ-aminobutyric acid-ergic activity in the hypothalamic arcuate nucleus is attenuated in the spontaneously hypertensive rat.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Arterial Pressure; Baroreflex; Denervation; Dose-Response | 2013 |
Paraventricular nucleus control of blood pressure in two-kidney, one-clip rats: effects of exercise training and resting blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Kidney; | 2013 |
Chronic infusion of enalaprilat into hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension and cardiac hypertrophy by restoring neurotransmitters and cytokines.
Topics: Angiotensin II; Animals; Cardiomegaly; Chemokine CCL2; Enalaprilat; gamma-Aminobutyric Acid; Glutami | 2014 |
Exercise training attenuates hypertension and cardiac hypertrophy by modulating neurotransmitters and cytokines in hypothalamic paraventricular nucleus.
Topics: Animals; Arterial Pressure; Cardiomegaly; Cytokines; gamma-Aminobutyric Acid; Glutamic Acid; Hyperte | 2014 |
Association of left atrial reservoir function with left atrial structural remodeling related to left ventricular dysfunction in asymptomatic patients with hypertension: evaluation by two-dimensional speckle-tracking echocardiography.
Topics: Atrial Function, Left; Echocardiography; Female; Follow-Up Studies; gamma-Aminobutyric Acid; Heart A | 2015 |
Characteristic expressions of GABA receptors and GABA producing/transporting molecules in rat kidney.
Topics: 4-Aminobutyrate Transaminase; Adult; Animals; Female; GABA Plasma Membrane Transport Proteins; gamma | 2014 |
Gastrointestinal intervention ameliorates high blood pressure through antagonizing overdrive of the sympathetic nerve in hypertensive patients and rats.
Topics: Adult; Animals; Biomarkers; Blood Pressure; Cardiovascular System; Cold-Shock Response; Diabetes Mel | 2014 |
Field trial of GABA-fortified rice plants and oral administration of milled rice in spontaneously hypertensive rats.
Topics: Administration, Oral; Amino Acids; Animals; Blood Pressure; Food, Fortified; gamma-Aminobutyric Acid | 2015 |
In vitro anti-inflammatory properties of fermented pepino (Solanum muricatum) milk by γ-aminobutyric acid-producing Lactobacillus brevis and an in vivo animal model for evaluating its effects on hypertension.
Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Disease Models, Animal; Fermentation; Fruit; Func | 2016 |
Cystathionine-β-Synthase Gene Transfer Into Rostral Ventrolateral Medulla Exacerbates Hypertension via Nitric Oxide in Spontaneously Hypertensive Rats.
Topics: Animals; Blood Pressure; Cystathionine beta-Synthase; Disease Models, Animal; Enzyme Induction; gamm | 2015 |
Role of GABAB receptor and L-Arg in GABA-induced vasorelaxation in non-diabetic and streptozotocin-induced diabetic rat vessels.
Topics: Animals; Arginine; Blood Pressure; Diabetes Mellitus, Experimental; GABA-B Receptor Antagonists; gam | 2015 |
Messenger RNA expression profile of sleep-related genes in peripheral blood cells in patients with chronic kidney disease.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Female; gamma-Aminobutyric Acid; Gene Expression Prof | 2016 |
Antihypertensive effect of a gamma-aminobutyric acid rich tomato cultivar 'DG03-9' in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; gamma-Aminobutyric Acid; H | 2010 |
Role of GABAergic neurones in the nucleus tractus solitarii in modulation of cardiovascular activity.
Topics: Animals; Baroreflex; Blood Pressure; Cardiovascular System; Disease Models, Animal; GABA-A Receptor | 2010 |
Antihypertensive effects of Lactobacillus-fermented milk orally administered to spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cultured | 2011 |
Antihypertensive effects of Lactobacillus-fermented milk orally administered to spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cultured | 2011 |
Antihypertensive effects of Lactobacillus-fermented milk orally administered to spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cultured | 2011 |
Antihypertensive effects of Lactobacillus-fermented milk orally administered to spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cultured | 2011 |
Antihypertensive effects of Lactobacillus-fermented milk orally administered to spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cultured | 2011 |
Antihypertensive effects of Lactobacillus-fermented milk orally administered to spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cultured | 2011 |
Antihypertensive effects of Lactobacillus-fermented milk orally administered to spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cultured | 2011 |
Antihypertensive effects of Lactobacillus-fermented milk orally administered to spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cultured | 2011 |
Antihypertensive effects of Lactobacillus-fermented milk orally administered to spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cultured | 2011 |
Altered regulation of the rostral ventrolateral medulla in hypertensive obese Zucker rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Brain Stem; Excita | 2011 |
Hsp70 promotes synaptic transmission in brain slices damaged by contact with blood clot.
Topics: Animals; Blood Coagulation; Brain; Cattle; Dose-Response Relationship, Drug; Electrophysiological Ph | 2012 |
Cranial polyneuropathy associated with vertebrobasilar dolichoectasia.
Topics: Abducens Nerve Diseases; Anticonvulsants; Carbamazepine; Cerebral Angiography; Cranial Nerve Disease | 2012 |
NKCC1 upregulation disrupts chloride homeostasis in the hypothalamus and increases neuronal activity-sympathetic drive in hypertension.
Topics: Animals; Blood Pressure; Blotting, Western; Cell Membrane; Chlorides; Electrophysiological Phenomena | 2012 |
Transcriptional upregulation of α2δ-1 elevates arterial smooth muscle cell voltage-dependent Ca2+ channel surface expression and cerebrovascular constriction in genetic hypertension.
Topics: Animals; Calcium Channels; Calcium Channels, L-Type; Cerebral Arteries; gamma-Aminobutyric Acid; Hyp | 2012 |
Reduction of nitric oxide-mediated γ-amino butyric acid release in rostral ventrolateral medulla is involved in superoxide-induced sympathoexcitation of hypertensive rats.
Topics: Animals; Arterial Pressure; Bicuculline; Cyclic N-Oxides; Disease Models, Animal; Down-Regulation; E | 2012 |
Inhibition of cardiac hypertrophy by probiotic-fermented purple sweet potato yogurt in spontaneously hypertensive rat hearts.
Topics: Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Calcineurin; Calcium-Calmodulin-Depende | 2012 |
Involvement of gamma-aminobutyric acid (GABA) B receptors in the hypotensive effect of systemically administered GABA in spontaneously hypertensive rats.
Topics: Animals; Dose-Response Relationship, Drug; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; ga | 2002 |
Activation of hypothalamic angiotensin receptors produces pressor responses via cholinergic inputs to the rostral ventrolateral medulla in normotensive and hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Carbachol; Choliner | 2002 |
Fos expression by glutamatergic neurons of the solitary tract nucleus after phenylephrine-induced hypertension in rats.
Topics: Animals; Baroreflex; Carrier Proteins; Cell Count; gamma-Aminobutyric Acid; Glutamate Decarboxylase; | 2003 |
Aqueous extract of Monascus purpureus M9011 prevents and reverses fructose-induced hypertension in rats.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Cholesterol; Cholesterol, HDL; Fructose; gamma- | 2003 |
Effect of gamma-aminobutyric acid (GABA) on normotensive or hypertensive rats and men.
Topics: Amino Acids; Animals; Blood Pressure; Blood Pressure Determination; gamma-Aminobutyric Acid; Hyperte | 1961 |
[Experience in the use of gamma-aminobutyric acid in our clinic].
Topics: Ambulatory Care Facilities; Amino Acids; Antifibrinolytic Agents; Cerebrovascular Disorders; gamma-A | 1962 |
[On the therapeutic effectiveness of gamma-aminobutyric acid and gamma-amino-beta-hydroxybutyric acid for cerebrovascular disorders and hypertension].
Topics: Amino Acids; Antifibrinolytic Agents; Cerebrovascular Disorders; gamma-Aminobutyric Acid; Hypertensi | 1962 |
Antihypertensive effect of gamma-amino butyric acid enriched soy products in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Diet; Dietary Supplements; gamma-Aminobutyric Acid | 2004 |
Gabapentin withdrawal syndrome in the presence of a taper.
Topics: Aged; Aged, 80 and over; Amines; Antimanic Agents; Bipolar Disorder; Chest Pain; Cyclohexanecarboxyl | 2005 |
Plasticity of GABAergic control of hypothalamic presympathetic neurons in hypertension.
Topics: Action Potentials; Animals; gamma-Aminobutyric Acid; Hypertension; Male; Medulla Oblongata; Neural P | 2006 |
Role of the renal nerves in gamma-aminobutyric acid-induced antihypertensive effect in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Creatinine; Denervation; Drinking; Ea | 2005 |
Inhibition of nociceptive responses of spinal cord neurones during hypertension involves the spinal GABAergic system and a pain modulatory center located at the caudal ventrolateral medulla.
Topics: Animals; Blood Pressure; gamma-Aminobutyric Acid; Gene Expression; Genes, fos; Hindlimb; Hypertensio | 2006 |
The effect of short-term lyophilized beer consumption on established hypertension in rats.
Topics: Animals; Antihypertensive Agents; Antioxidants; Beer; Freeze Drying; gamma-Aminobutyric Acid; Hypert | 2007 |
Antihypertensive and natriuretic effects of less-sodium soy sauce containing gamma-aminobutyric acid in spontaneously hypertensive rats.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; gamma-Aminobutyric Acid; Hyp | 2007 |
Effects of dietary administration of plant-derived anthocyanin-rich colors to spontaneously hypertensive rats.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Anthocyanins; Blood Pressur | 2007 |
Pregabalin-induced remission in a 62-year-old woman with a 20-year history of vulvodynia.
Topics: Amitriptyline; Analgesics; Anti-Ulcer Agents; Anticoagulants; Antidepressive Agents; Anxiety; Cardio | 2007 |
GABA receptor binding and hemodynamic responses to ICV GABA in adult spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain; gamma-Aminobutyric Acid; Heart Rate; Hemody | 1983 |
The GABA/benzodiazepine receptor complex in the nervous system of a hypertensive strain of rat.
Topics: Aging; Animals; Brain; Cerebellum; Cerebral Cortex; Flunitrazepam; gamma-Aminobutyric Acid; Glutamat | 1984 |
Central gamma-aminobutyric acid involvement in blood pressure control.
Topics: Animals; Bicuculline; Blood Pressure; Brain; Cats; Disease Models, Animal; gamma-Aminobutyric Acid; | 1984 |
Increased cardiovascular responsiveness to GABAergic stimulation in DOCA-salt hypertensive rats.
Topics: 4-Aminobutyrate Transaminase; Animals; Blood Pressure; Brain; Desoxycorticosterone; Ethanolamines; g | 1984 |
In vivo release of endogenous catecholamines, histamine and GABA in the hypothalamus of Wistar Kyoto and spontaneously hypertensive rats.
Topics: Animals; Catecholamines; Dopamine; Epinephrine; gamma-Aminobutyric Acid; Histamine; Hypertension; Hy | 1983 |
Ultrastructural studies on catecholaminergic terminals and GABAergic neurons in nucleus tractus solitarius of the rat medulla oblongata.
Topics: Animals; Catecholamines; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Histocytochemistry; Hyper | 1984 |
Evidence that a GABAergic mechanism influences the development of DOCA-salt hypertension in the rat.
Topics: Animals; Blood Pressure; Body Weight; Desoxycorticosterone; gamma-Aminobutyric Acid; Hypertension; M | 1982 |
GABA and bicuculline-induced blood pressure changes in spontaneously hypertensive rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Bicuculline; Blood Pressure; Drug Interactions; gamma | 1993 |
Effect of green tea rich in gamma-aminobutyric acid on blood pressure of Dahl salt-sensitive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Disease Models, Animal; Female; gamma | 1995 |
Enhancement of GABAergic system activity by metoprolol in spontaneously hypertensive rats.
Topics: Analysis of Variance; Animals; Blood Pressure; Brain; Corpus Striatum; Dihydralazine; gamma-Aminobut | 1993 |
Alterations in noradrenergic physiological characteristics with DOCA-hypertension: interaction between norepinephrine and GABA in rat lateral hypothalamus.
Topics: Animals; Desoxycorticosterone; Drug Interactions; Evoked Potentials; gamma-Aminobutyric Acid; Hypert | 1993 |
Central GABAergic mechanisms are defective in salt-induced hypertension in borderline hypertensive rats.
Topics: Animals; Antihypertensive Agents; Bicuculline; Blood Pressure; Consciousness; GABA Antagonists; gamm | 1995 |
Changes in levels of monoamines and their metabolites in incompletely ischemic brains of spontaneously hypertensive rats.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Biogenic Monoamines; Brain; Cerebral Cortex; Corpus | 1995 |
Functional alteration of the GABAB receptor in the brain of spontaneously hypertensive rats.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aging; Animals; Blood Pressure; Brain; Brain Chemist | 1995 |
Is L-DOPA a neurotransmitter of the primary baroreceptor afferents terminating in the nucleus tractus solitarii of rats?
Topics: Afferent Pathways; alpha-Methyltyrosine; Animals; gamma-Aminobutyric Acid; Hypertension; Levodopa; M | 1998 |
Organization and transmitter specificity of medullary neurons activated by sustained hypertension: implications for understanding baroreceptor reflex circuitry.
Topics: Animals; Baroreflex; Biomarkers; Cardiovascular System; Catecholamines; Dose-Response Relationship, | 1998 |
Age-related development of gamma-aminobutyric acid (GABA)B receptor functions in various brain regions of spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Aging; Animals; Baclofen; Brain; Corpus Striatum; Cyclic AMP; GABA Agonists; gamm | 1998 |
Role of the central nervous system in the development of hypertension produced by chronic nitric oxide blockade in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Central Nervous System; Enzyme Inhibi | 2001 |
Influence of an abrupt increase in blood pressure on the blood-brain barrier permeability during acute hypertension and epileptic seizures.
Topics: Acute Disease; Adrenergic Agonists; Animals; Blood Pressure; Blood-Brain Barrier; Capillary Permeabi | 2001 |
Inhibition of the hypothalamic paraventricular nucleus in spontaneously hypertensive rats dramatically reduces sympathetic vasomotor tone.
Topics: Animals; Bicuculline; Blood Pressure; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hear | 2002 |
Inhibition of neurons in commissural nucleus of solitary tract reduces sympathetic nerve activity in SHR.
Topics: Animals; Blood Pressure; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Microinjections; Neurons | 2002 |
Effects of electroacupuncture of "zusanli" acupoint on high blood pressure and blood hyperviscosity in stress rats.
Topics: Acupuncture Points; Acupuncture Therapy; Animals; Blood Viscosity; Electroacupuncture; gamma-Aminobu | 1992 |
Decreased hypothalamic and medullary GABA turnover in spontaneously hypertensive rats.
Topics: Aminooxyacetic Acid; Animals; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Hyperte | 1992 |
Effects of gamma-vinyl GABA (vigabatrin) on blood pressure and body weight of hypertensive and normotensive rats.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Blood Pressure; Body Weight; Brain; gamma-Ami | 1992 |
Effect of clonidine on blood pressure and GABAergic mechanisms in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Clonidine; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Heart R | 1991 |
Excitatory and inhibitory amino acid changes in ischemic brain regions in spontaneously hypertensive rats.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Aci | 1991 |
Chronic central GABAergic stimulation attenuates hypothalamic hyperactivity and development of spontaneous hypertension in rats.
Topics: Animals; Blood Pressure; Electric Stimulation; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Hy | 1990 |
Evidence for clonidine presynaptically modulating amino acid release in the rostral ventral medulla: role in hypertension.
Topics: Amino Acids; Animals; Aspartic Acid; Clonidine; Female; gamma-Aminobutyric Acid; Glutamates; Glutami | 1990 |
Altered amino acid levels in brainstem regions of spontaneously hypertensive rats.
Topics: Amino Acids; Animals; beta-Alanine; Brain Stem; Chromatography, High Pressure Liquid; gamma-Aminobut | 1989 |
[Membrane potential and transport of neuromediators in synaptosomes of the brain of rats with spontaneous hypertension].
Topics: Acetylcholine; Animals; Brain; gamma-Aminobutyric Acid; Hypertension; Male; Membrane Potentials; Neu | 1985 |
Role of the nucleus ambiguus in the regulation of heart rate and arterial pressure.
Topics: Animals; Blood Pressure; Bradycardia; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Heart Rate | 1988 |
Enhanced pressor response to GABA in the nucleus tractus solitarii of the spontaneously hypertensive rat.
Topics: Animals; Baclofen; Blood Pressure; Brain Stem; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Ma | 1988 |
Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat.
Topics: Animals; Blood Pressure; Dopamine; gamma-Aminobutyric Acid; Hypertension; Hypothalamus; Male; Norepi | 1988 |
Central GABA-ergic stimulation attenuates hypertension and hypothalamic hyperactivity in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Hypothalamus; Male; Rats | 1986 |
Participation of GABAergic mechanisms in the hypotensive and bradycardic effects of clonidine: experimental study in conscious normotensive and hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Desoxycorticosterone; gamma-Aminobutyric Acid; Heart Rate; Hyper | 1987 |
Enhanced depressor effect of muscimol in the DOCA/NaCl hypertensive rat: evidence for altered GABAergic activity in brain.
Topics: Animals; Bicuculline; Blood Pressure; Brain Chemistry; Clonidine; Desoxycorticosterone; Drug Interac | 1985 |
[Blood serotonin during gammalon treatment of patients with acute cerebrovascular disorders].
Topics: Acute Disease; Adult; Aged; Aminobutyrates; Cerebrovascular Disorders; Female; gamma-Aminobutyric Ac | 1974 |