Page last updated: 2024-12-05

buthiazide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

buthiazide: 3-isobutyl analog of hydrochlorothiazide; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID16274
CHEMBL ID2104197
CHEBI ID135492
SCHEMBL ID309110
MeSH IDM0054684

Synonyms (41)

Synonym
6-chloro-3-(2-methylpropyl)-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
buthiazide
D03189
buthiazide (usan)
2043-38-1
butizide (inn)
su 6187
2h-1,2,4-benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-(2-methylpropyl)-, 1,1-dioxide
einecs 218-048-8
isobutylhydrochlorothiazide
thiabutazide
saltucin
6-chloro-3,4-dihydro-3-isobutyl-2h-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide
eunephran
butizidum [inn-latin]
s 3500
buthiazide [usan]
butizide
6-chloro-3,4-dihydro-3-isobutyl-2h-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
butizida [inn-spanish]
CHEBI:135492
FT-0663925
unii-w00ssd35vw
butizidum
butizide [inn]
w00ssd35vw ,
butizida
CHEMBL2104197
S-3500 ,
butizide [mart.]
butizide [who-dd]
buthiazide [mi]
butizid
SCHEMBL309110
DTXSID6022713
6-chloro-3-(2-methylpropyl)-1,1-dioxo-3,4-dihydro-2h-1lambda6,2,4-benzothiadiazine-7-sulfonamide
Q5002531
6-chloro-3-isobutyl-3,4-dihydro-2h-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide
EX-A6686
buthiazide-d10(major)
AKOS040750939
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
benzothiadiazineHeterocyclic compound of a ring with sulfur and two nitrogen atoms fused to a benzene ring. Members inhibit sodium-potassium-chloride symporters and are used as diuretics.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (29)

TimeframeStudies, This Drug (%)All Drugs %
pre-199019 (65.52)18.7374
1990's2 (6.90)18.2507
2000's6 (20.69)29.6817
2010's2 (6.90)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 16.08

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index16.08 (24.57)
Research Supply Index3.66 (2.92)
Research Growth Index4.56 (4.65)
Search Engine Demand Index10.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (16.08)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials8 (26.67%)5.53%
Reviews0 (0.00%)6.00%
Case Studies4 (13.33%)4.05%
Observational0 (0.00%)0.25%
Other18 (60.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]