antipyrine has been researched along with Hypertension in 26 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of hepatic drug-metabolizing enzyme activity for plasma propranolol and sotalol levels was investigated in 68 patients with hypertension or angina pectoris by comparing elimination rate with antipyrine kinetics and cytochrome P-450 content in the liver." | 3.66 | Plasma clearance of propranolol and sotalol and hepatic drug-metabolizing enzyme activity. ( Anttila, M; Järvensivu, P; Pelkonen, RO; Sotaniemi, EA; Sundquist, H, 1979) |
| "In the last few decades, medical treatment for stroke has made progress greatly." | 2.53 | [History and current status of medical treatment for stroke]. ( Yagita, Y, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (50.00) | 18.7374 |
| 1990's | 8 (30.77) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 2 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Terzioğlu, K | 1 |
| Ediger, D | 1 |
| Tülümen Öztürk, R | 1 |
| Durmuş, E | 1 |
| Alışır, MF | 1 |
| Yagita, Y | 1 |
| KOVALEVA, NT | 1 |
| Shinohara, Y | 1 |
| Fushimi, H | 1 |
| Tsujimoto, I | 1 |
| Hikoso, S | 1 |
| Yamaguchi, O | 1 |
| Kashiwase, K | 1 |
| Nakai, A | 1 |
| Takeda, T | 1 |
| Watanabe, T | 1 |
| Taniike, M | 1 |
| Matsumura, Y | 1 |
| Nishida, K | 1 |
| Hori, M | 1 |
| Kogo, M | 1 |
| Otsu, K | 1 |
| Adamska-Dyniewska, H | 4 |
| Pruszczyński, J | 2 |
| Wichan, P | 1 |
| Fredriksson, K | 1 |
| Ingvar, M | 1 |
| Johansson, BB | 1 |
| Kalow, W | 1 |
| Dziekański, S | 2 |
| Pörsti, I | 1 |
| Ylitalo, P | 1 |
| Lanchote, VL | 2 |
| Ping, WC | 2 |
| Santos, SR | 2 |
| Fouyas, IP | 1 |
| Kelly, PA | 1 |
| Ritchie, IM | 1 |
| Whittle, IR | 1 |
| Watanabe, H | 1 |
| Kumon, Y | 1 |
| Ohta, S | 1 |
| Sakaki, S | 1 |
| Matsuda, S | 1 |
| Sakanaka, M | 1 |
| Gajewska, B | 1 |
| Sotaniemi, EA | 1 |
| Anttila, M | 1 |
| Pelkonen, RO | 1 |
| Järvensivu, P | 1 |
| Sundquist, H | 1 |
| Raison, JM | 1 |
| Achimastos, AM | 1 |
| Safar, ME | 1 |
| Ben-Zvi, Z | 1 |
| Hreash, F | 1 |
| Kaplanski, J | 1 |
| Kuhn, DC | 1 |
| Walenga, RW | 1 |
| Stuart, MJ | 1 |
| Kagaya, Y | 1 |
| Kanno, Y | 1 |
| Takeyama, D | 1 |
| Ishide, N | 1 |
| Maruyama, Y | 1 |
| Takahashi, T | 1 |
| Ido, T | 1 |
| Takishima, T | 1 |
| Albright, RE | 1 |
| Friedman, AH | 1 |
| Fram, EK | 1 |
| Harbury, OL | 1 |
| Molter, BA | 1 |
| Skatoff, JH | 1 |
| Harris, CC | 1 |
| Coleman, RE | 1 |
| Drayer, BP | 1 |
| Burke, AM | 1 |
| Greenberg, JH | 1 |
| Sladky, J | 1 |
| Reivich, M | 1 |
| Dinsdale, HB | 1 |
| Robertson, DM | 1 |
| Haas, RA | 1 |
| Johansson, B | 1 |
3 reviews available for antipyrine and Hypertension
| Article | Year |
|---|---|
[History and current status of medical treatment for stroke].
Topics: Anticoagulants; Antihypertensive Agents; Antipyrine; Edaravone; Fibrinolytic Agents; Humans; Hydroxy | 2016 |
[Clinical guidelines for stroke].
Topics: Anticoagulants; Antipyrine; Arginine; Aspirin; Brain Edema; Edaravone; Fibrinolytic Agents; Free Rad | 2004 |
[Treatment of cerebral infarction patients with IGT].
Topics: Antidepressive Agents; Antipyrine; Atorvastatin; Cerebral Infarction; Edaravone; Free Radical Scaven | 2005 |
1 trial available for antipyrine and Hypertension
| Article | Year |
|---|---|
Influence of renal failure on cytochrome P450 activity in hypertensive patients using a "cocktail" of antipyrine and nifedipine.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Antipyrine; Biotransformati | 1996 |
22 other studies available for antipyrine and Hypertension
| Article | Year |
|---|---|
Kounis syndrome not induced but prevented by the implantation of a drug-eluting stent: a case report.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Diabetes Mellitus, Type 2; | 2017 |
[Commotional experimental hypertension].
Topics: Antipyrine; Brain; Brain Injuries; Humans; Hypertension | 1952 |
The antioxidant edaravone attenuates pressure overload-induced left ventricular hypertrophy.
Topics: Animals; Antioxidants; Antipyrine; Edaravone; Enzyme Activation; Free Radical Scavengers; Hypertensi | 2005 |
[Effect of beta-adrenolytic drugs on hepatic clearance of antipyrine].
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Antipyrine; Biotransformation; Coronary Diseas | 1984 |
Regional cerebral blood flow in conscious stroke-prone spontaneously hypertensive rats.
Topics: Animals; Antipyrine; Autoradiography; Blood Glucose; Carbon Dioxide; Cerebrovascular Circulation; He | 1984 |
Pharmacoanthropology: outline, problems, and the nature of case histories.
Topics: Antipyrine; Ethnicity; Gene Frequency; Genetics, Population; Genotype; Heterozygote; Humans; Hyperte | 1984 |
[Effect of labetalol on antipyrine metabolism in the liver].
Topics: Adult; Aged; Antipyrine; Biotransformation; Ethanolamines; Humans; Hypertension; Kinetics; Labetalol | 1984 |
Penetration of some compounds through blood-brain and blood-testis barriers in chronically hypertensive rats.
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Animals; Antipyrine; Blood-Brain Barrier; Brain; Carbon Radiois | 1984 |
Cerebrovascular effects of nitric oxide manipulation in spontaneously hypertensive rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Autoradiography; Blood Pressure; Cereb | 1997 |
Determination of antipyrine and metabolites in plasma of a patient with mild renal failure.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Chromatography, High Pressure Liquid; Ed | 1997 |
Changes in protein synthesis and calcium homeostasis in the thalamus of spontaneously hypertensive rats with focal cerebral ischemia.
Topics: Animals; Antipyrine; Autoradiography; Calcium; Calcium Radioisotopes; Homeostasis; Hypertension; Isc | 1998 |
[Effect of propranolol on the ability of the liver to metabolize drugs in patients with hypertension].
Topics: Adult; Aged; Antipyrine; Female; Humans; Hypertension; Indocyanine Green; Liver; Male; Middle Aged; | 1979 |
Plasma clearance of propranolol and sotalol and hepatic drug-metabolizing enzyme activity.
Topics: Adult; Aged; Angina Pectoris; Antipyrine; Cytochrome P-450 Enzyme System; Female; Half-Life; Humans; | 1979 |
Sex-dependence of body fat distribution in patients with obesity and hypertension.
Topics: Adipose Tissue; Adult; Antipyrine; Blood Pressure; Body Fluids; Female; Humans; Hypertension; Inulin | 1992 |
Disposition of hexobarbitone and antipyrine in DOCA-hypertensive rats.
Topics: Animals; Antipyrine; Desoxycorticosterone; Hemodynamics; Hexobarbital; Hypertension; Liver; Male; Mi | 1991 |
A prostacyclin analogue crosses the in vitro perfused human placenta and improves transfer in some pathologic states.
Topics: Antipyrine; Diabetes Mellitus, Type 1; Epoprostenol; Female; Humans; Hypertension; Ibuprofen; In Vit | 1991 |
Effects of long-term pressure overload on regional myocardial glucose and free fatty acid uptake in rats. A quantitative autoradiographic study.
Topics: Acute Disease; Animals; Antipyrine; Autoradiography; Blood Glucose; Chronic Disease; Fatty Acids; Fa | 1990 |
The effect of six beta-adrenolytics and labetalol on hepatic biotransformation studied by antipyrine test, in man.
Topics: Adrenergic beta-Antagonists; Adult; Antipyrine; Biotransformation; Coronary Disease; Half-Life; Huma | 1986 |
Comparison of [125I]HIPDm and [125I]iodoantipyrine in quantifying regional cerebral blood flow in rats.
Topics: Acidosis, Respiratory; Alkalosis, Respiratory; Animals; Antipyrine; Blood-Brain Barrier; Cerebrovasc | 1988 |
Regional variation in cerebral perfusion during acute hypertension.
Topics: Animals; Antipyrine; Autoradiography; Cerebrovascular Circulation; Homeostasis; Hypertension; Male; | 1987 |
Acute hypertension and prolonged focal cerebral ischemia.
Topics: Angiotensin II; Animals; Antipyrine; Autoradiography; Carbon Radioisotopes; Cerebrovascular Circulat | 1973 |
Blood-brain barrier dysfunction in acute arterial hypertension after papaverine-induced vasodilatation.
Topics: Albumins; Animals; Antipyrine; Azo Compounds; Blood-Brain Barrier; Brain; Capillary Permeability; Ca | 1974 |