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alfuzosin and Hypertension

alfuzosin has been researched along with Hypertension in 16 studies

alfuzosin: structure given in first source

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"The objective of this study was to assess the efficacy and safety of alfuzosin 10 mg monotherapy or combined antihypertensive medication on blood pressure (BP) in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH/LUTS) with or without antihypertensive medication."9.20Multicenter, prospective, comparative cohort study evaluating the efficacy and safety of alfuzosin 10 mg with regard to blood pressure in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia with or without antihypertensive med ( Chung, WS; Hyun, JS; Kim, SW; Lee, SW; Min, KS; Moon, DG; Moon, KH; Park, JK; Park, K; Ryu, JK; Yang, DY; Yang, SK; Zhang, LT, 2015)
"To assess the efficacy and safety, and determine the optimal dosage, of a once-daily (OD) formulation of the clinically uroselective alpha(1)-blocker, alfuzosin, in patients with lower urinary tract symptoms and symptomatic benign prostatic hyperplasia."9.09Efficacy and safety of once-daily alfuzosin in the treatment of lower urinary tract symptoms and clinical benign prostatic hyperplasia: a randomized, placebo-controlled trial. ( Roehrborn, CG, 2001)
"The new alpha 1-blocker alfuzosin was compared with propranolol as monotherapy for hypertension in a double-blind, parallel group study of 8-week duration in 40 patients with essential hypertension."9.07Comparison of the new alpha 1-blocker alfuzosin with propranolol as first-line therapy in hypertension. ( Antonacci, A; Bombelli, M; Leto di Priolo, S; Libretti, A; Marazzi, ME; Pirrelli, A; Sega, R; Vulpis, V, 1991)
"Alfuzosin did not cause any significant change in supine or upright heart rate."5.27Dose-titration study of alfuzosin, a new alpha 1-adrenoceptor blocker, in essential hypertension. ( Cazor, JL; Cocco, G; Leto di Priolo, S; Priore, P; Sfrisi, C, 1988)
"The objective of this study was to assess the efficacy and safety of alfuzosin 10 mg monotherapy or combined antihypertensive medication on blood pressure (BP) in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH/LUTS) with or without antihypertensive medication."5.20Multicenter, prospective, comparative cohort study evaluating the efficacy and safety of alfuzosin 10 mg with regard to blood pressure in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia with or without antihypertensive med ( Chung, WS; Hyun, JS; Kim, SW; Lee, SW; Min, KS; Moon, DG; Moon, KH; Park, JK; Park, K; Ryu, JK; Yang, DY; Yang, SK; Zhang, LT, 2015)
"To assess the efficacy and safety, and determine the optimal dosage, of a once-daily (OD) formulation of the clinically uroselective alpha(1)-blocker, alfuzosin, in patients with lower urinary tract symptoms and symptomatic benign prostatic hyperplasia."5.09Efficacy and safety of once-daily alfuzosin in the treatment of lower urinary tract symptoms and clinical benign prostatic hyperplasia: a randomized, placebo-controlled trial. ( Roehrborn, CG, 2001)
"Two placebo-controlled studies involving 588 patients (292 receiving SR alfuzosin 5 mg twice daily and 296 a placebo) were pooled; 51% of the patients were > or = 65 years of age and 43% had associated cardiovascular disease including hypertension and/or were receiving concomitant antihypertensive drugs."5.08Clinical uroselectivity: evidence from patients treated with slow-release alfuzosin for symptomatic benign prostatic obstruction. ( Buzelin, JM; Delauche-Cavallier, MC; Geffriaud-Ricouard, C; Roth, S; Santoni, JP, 1997)
"The new alpha 1-blocker alfuzosin was compared with propranolol as monotherapy for hypertension in a double-blind, parallel group study of 8-week duration in 40 patients with essential hypertension."5.07Comparison of the new alpha 1-blocker alfuzosin with propranolol as first-line therapy in hypertension. ( Antonacci, A; Bombelli, M; Leto di Priolo, S; Libretti, A; Marazzi, ME; Pirrelli, A; Sega, R; Vulpis, V, 1991)
"To evaluate risk factors (hypertension, diabetes mellitus, and current tamsulosin, alfuzosin, terazosin, or doxazosin use) for intraoperative floppy iris syndrome (IFIS) in patients undergoing phacoemulsification cataract surgery."4.87Risk factors for intraoperative floppy iris syndrome: a meta-analysis. ( Chatziralli, IP; Sergentanis, TN, 2011)
"Alfuzosin (10 mg) OD is effective and well tolerated, and it has marginal effects on blood pressure, including in elderly patients and those with hypertension, ischemic heart disease or diabetes and those receiving antihypertensive agents."3.73Age, comorbidity and hypertensive co-medication do not affect cardiovascular tolerability of 10 mg alfuzosin once daily. ( Alcaraz, A; Elhilali, M; Emberton, M; Hartung, R; Harving, N; Matzkin, H; Vallancien, G; van Moorselaar, J, 2006)
"Tamsulosin has selectivity for the a alpha(1) and alpha(1d) receptor subtypes."2.42Role of the newer alpha, -adrenergic-receptor antagonists in the treatment of benign prostatic hyperplasia-related lower urinary tract symptoms. ( Lowe, FC, 2004)
"Doxazosin GITS treatment resulted in optimal management of BP within the normal range, especially in pharmacologically or physiologically hypertensive patients."1.36Effects of α-blocker 'add on' treatment on blood pressure in symptomatic BPH with or without concomitant hypertension. ( Chung, BH; Lee, SH; Mah, SY; Park, KK, 2010)
"Alfuzosin did not cause any significant change in supine or upright heart rate."1.27Dose-titration study of alfuzosin, a new alpha 1-adrenoceptor blocker, in essential hypertension. ( Cazor, JL; Cocco, G; Leto di Priolo, S; Priore, P; Sfrisi, C, 1988)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19903 (18.75)18.7374
1990's2 (12.50)18.2507
2000's7 (43.75)29.6817
2010's4 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Leeuw, PW1
de Bos, R1
van Soest, GA1
Willemse, PJ1
Birkenhäger, WH1
Ohyama, K1
Hori, Y1
Sugiura, M1
Zhang, LT1
Lee, SW1
Park, K1
Chung, WS1
Kim, SW1
Hyun, JS1
Moon, DG1
Yang, SK1
Ryu, JK1
Yang, DY1
Moon, KH1
Min, KS1
Park, JK1
Lee, SH1
Park, KK1
Mah, SY1
Chung, BH1
Chatziralli, IP1
Sergentanis, TN1
Lowe, FC1
Hartung, R1
Matzkin, H1
Alcaraz, A1
Emberton, M1
Harving, N1
van Moorselaar, J1
Elhilali, M1
Vallancien, G1
Cheung, CM1
Awan, MA1
Peh, KK1
Sandramouli, S1
Buzelin, JM1
Delauche-Cavallier, MC1
Roth, S1
Geffriaud-Ricouard, C1
Santoni, JP1
Zabala, S1
Thomson, C1
Valdearcos, S1
Gascón, A1
Pina, MA1
Michel, MC1
Flannery, MT1
Narayan, P1
Roehrborn, CG1
Chess-Williams, R1
Sega, R1
Marazzi, ME1
Bombelli, M1
Vulpis, V1
Antonacci, A1
Leto di Priolo, S2
Pirrelli, A1
Libretti, A1
Priore, P1
Cocco, G1
Sfrisi, C1
Cazor, JL1
Manoury, PM1
Binet, JL1
Dumas, AP1
Lefèvre-Borg, F1
Cavero, I1

Reviews

4 reviews available for alfuzosin and Hypertension

ArticleYear
Risk factors for intraoperative floppy iris syndrome: a meta-analysis.
    Ophthalmology, 2011, Volume: 118, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Diabetes Complications; Doxazosin; Humans; Hypertension; In

2011
Role of the newer alpha, -adrenergic-receptor antagonists in the treatment of benign prostatic hyperplasia-related lower urinary tract symptoms.
    Clinical therapeutics, 2004, Volume: 26, Issue:11

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Clinical Trials as Topic; Hum

2004
Worldwide experience with alfuzosin and tamsulosin.
    Urology, 2001, Volume: 58, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Controlled Clinical Trials as Topic; Hu

2001
The use of alpha-adrenoceptor antagonists in lower urinary tract disease.
    Expert opinion on pharmacotherapy, 2002, Volume: 3, Issue:2

    Topics: Adrenergic alpha-Antagonists; Humans; Hypertension; Male; Prostatic Hyperplasia; Quinazolines; Sulfo

2002

Trials

4 trials available for alfuzosin and Hypertension

ArticleYear
Multicenter, prospective, comparative cohort study evaluating the efficacy and safety of alfuzosin 10 mg with regard to blood pressure in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia with or without antihypertensive med
    Clinical interventions in aging, 2015, Volume: 10

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Humans; Hypertension; Lowe

2015
Clinical uroselectivity: evidence from patients treated with slow-release alfuzosin for symptomatic benign prostatic obstruction.
    British journal of urology, 1997, Volume: 79, Issue:6

    Topics: Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases

1997
Efficacy and safety of once-daily alfuzosin in the treatment of lower urinary tract symptoms and clinical benign prostatic hyperplasia: a randomized, placebo-controlled trial.
    Urology, 2001, Volume: 58, Issue:6

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Antihypertensive Agents; Canada; Double-Blind

2001
Comparison of the new alpha 1-blocker alfuzosin with propranolol as first-line therapy in hypertension.
    Pharmacological research, 1991, Volume: 24, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Double-Blind Method; E

1991

Other Studies

8 other studies available for alfuzosin and Hypertension

ArticleYear
Effect of sympathetic stimulation on inactive renin.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:11-12

    Topics: Acoustic Stimulation; Adrenergic alpha-Antagonists; Adult; Atenolol; Blood Pressure; Enzyme Precurso

1982
Evaluation of syncope association with α
    Die Pharmazie, 2019, 12-01, Volume: 74, Issue:12

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Doxazosin; Humans; Hypertension; Indoles; Male; Midd

2019
Effects of α-blocker 'add on' treatment on blood pressure in symptomatic BPH with or without concomitant hypertension.
    Prostate cancer and prostatic diseases, 2010, Volume: 13, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Blood Pressure; Doxazosin; Drug Combina

2010
Age, comorbidity and hypertensive co-medication do not affect cardiovascular tolerability of 10 mg alfuzosin once daily.
    The Journal of urology, 2006, Volume: 175, Issue:2

    Topics: Adrenergic alpha-Antagonists; Age Factors; Aged; Antihypertensive Agents; Cardiovascular Diseases; D

2006
Incidence of intraoperative floppy iris syndrome in patients on either systemic or topical alpha1-adrenoceptor antagonist.
    American journal of ophthalmology, 2007, Volume: 143, Issue:6

    Topics: Administration, Topical; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adul

2007
Alfuzosin-induced hepatotoxicity.
    Journal of clinical pharmacy and therapeutics, 2000, Volume: 25, Issue:1

    Topics: Acute Disease; Antihypertensive Agents; Chemical and Drug Induced Liver Injury; Humans; Hypertension

2000
Dose-titration study of alfuzosin, a new alpha 1-adrenoceptor blocker, in essential hypertension.
    European journal of clinical pharmacology, 1988, Volume: 35, Issue:1

    Topics: Adrenergic alpha-Antagonists; Aged; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart

1988
Synthesis and antihypertensive activity of a series of 4-amino-6,7-dimethoxyquinazoline derivatives.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:1

    Topics: Animals; Chemical Phenomena; Chemistry; Hypertension; Male; Quinazolines; Rats; Rats, Inbred SHR; St

1986