A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
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| "Screening for neuroblastoma is possible in the health care system of the United Kingdom." | ( Bell, S; Cole, M; Craft, AW; Dale, G; McGill, AC; Parker, L; Seviour, JA; Smith, J, 1992) |
| "Neuroblastoma is among the most common malignancies of childhood." | ( Schor, NF, 1992) |
| "Neuroblastoma is the most common solid tumor of children less than 5 years of age; yet the biology of this tumor is poorly understood." | ( Fleshman, DJ; O'Dorisio, MS; O'Dorisio, TM; Qualman, SJ, 1992) |
| "Disseminated neuroblastoma is a malignancy of children often treated by intensive chemotherapy/radiotherapy followed by autologous bone marrow transplantation (ABMT)." | ( Bartholomew, C; Brenner, MK; Buschle, M; Foreman, NK; Ihle, JN; Moen, RC; Rill, DR; Santana, VM, 1992) |
| "Childhood neuroblastoma is a neural crest-derived tumor that presents most commonly during this period of life." | ( Watts, RG, 1992) |
| "Neuroblastoma is among the most common malignancies of childhood." | ( Schor, NF, 1991) |
| "Neuroblastomas are malignant childhood neoplasms that arise from derivatives of the neural crest." | ( Chagnovich, D; Cohn, SL; Cowan, J; Foley, J; Mason, KL; Parysek, LM; Salwen, HR, 1991) |
| "Neuroblastoma is a potentially curable childhood malignancy with survival rates of 20% reported even in advanced disease." | ( Gordon, I; Hall-Craggs, MA; Pritchard, J; Shaw, D, 1990) |
| "Neuroblastoma is the third most frequent malignant tumor in childhood." | ( Berthold, F; Bruchelt, G; Dopfer, R; Ehninger, G; Einsele, H; Handgretinger, R; Klingebiel, T; Niethammer, D; Rister, M; Stollmann, B, 1989) |
| "Treatment of neuroblastoma is an unsolved problem of pediatric oncology." | ( Bruchelt, G; Buck, J; Dopfer, R; Feine, U; Girgert, R; Kaiser, W; Klingebiel, T; Meinke, J; Müller-Schauenburg, W; Treuner, J, 1986) |
| "Neuroblastoma is an uncommon tumour arising from neural crest tissue." | ( Krikke, AP; van der Jagt, EJ, 1989) |
| "Neuroblastoma is a childhood solid tumor composed of primitive cells derived from precursors of the autonomic nervous system." | ( Abemayor, E; Sidell, N, 1989) |
| "Neuroblastoma is one of the most common solid tumors of childhood and is notable for its ability to spontaneously regress and, in some instances, to differentiate to less malignant ganglioneuromas." | ( Bowen, T; Hammersley-Straw, D; Hayes, A; McGarry, RC, 1989) |
| "Neuroblastoma is the most common solid tumour of childhood with an incidence of about 1:10,000 births." | ( Craft, AW; Dale, G; McGill, A; Seviour, J; Spence, EM, 1989) |
| "Neuroblastoma is the most common fatal solid tumour of childhood." | ( Auray-Blais, C; Bernstein, M; Clow, CL; Dougherty, GE; Giguère, R; Gregory, D; Laberge, C; Lemieux, B; Scriver, CR; Weisdorf, T, 1987) |
| "More than 90% of neuroblastoma are MIBG positive, and therefore MIBG imaging is now considered the most valuable means of diagnosis and staging of these tumors." | ( de Kraker, J; Hoefnagel, CA; Voûte, PA, 1988) |
| "Neuroblastoma are discussed." | ( Caballero, O; Castel, V; Esquembre, C; Ferris, J; Verdeguer, A, 1987) |
| "Neuroblastoma is a disease in which easily measured tumor markers are excreted." | ( Tuchman, M; Woods, WG, 1987) |
| "Neuroblastoma is a lethal and not uncommon tumor in childhood." | ( Edeling, CJ; Frederiksen, PB; Jeppesen, P; Kamper, J, 1987) |
| "Neuroblastoma is well recognized as a cause of soft tissue uptake of Tc-99m MDP." | ( Heyman, S; McCarthy, KE, 1986) |
| "Neuroblastoma is a lethal and not uncommon tumor in childhood." | ( Büchler Frederiksen, P; Edeling, CJ; Jeppesen, P; Kamper, J, 1986) |
| "Neuroblastoma is one of the malignant childhood tumors which have a dismal prognosis, but is known to occasionally mature into benign histology spontaneously." | ( Hayakawa, K; Inoue, S; Munakata, H; Nara, K; Ono, K; Sato, S; Takahashi, K, 1985) |
| "Neuroblastoma is one of the commoner tumors of infancy and childhood." | ( Finklestein, JZ; Gilchrist, GS, 1972) |
| "However, neuroblastoma is known to maturate into benign ganglioneuroma spontaneously or induced by certain chemicals." | ( Imashuku, S; Nakajima, F; Todo, S, 1983) |
| "Neuroblastomas are malignant tumors derived embryonically from the neural crest." | ( Bekri, S; Candito, M; Chambon, P; Deville, A; Soler, C; Thyss, A, 1996) |
| "Infants with neuroblastoma are known to have a better prognosis than older children." | ( Kurosaki, N; Miyazaki, S; Mizote, H; Ogami, H; Sera, Y; Suita, S; Takamatsu, H; Tasaka, H; Ueda, K; Zaizen, Y, 1995) |
| "Human neuroblastomas are characterized by cytogenetic and molecular analysis as frequently containing deletions of distal 1p." | ( Brodeur, GM; Kaufman, BA; Marshall, HN; White, PS, 1993) |
| "Neuroblastoma is the most frequent tumour of the childhood under the age of 5." | ( Barbaroux, C; Fridman, WH; Manil, L; Michon, J; Perdereau, B; Rosin, N; Validire, P; Zucker, JM, 1994) |
| "Neuroblastoma is the most common extracranial solid tumor of children." | ( Chen, F; O'Dorisio, MS; O'Dorisio, TM; Qualman, SJ; Wray, D, 1994) |
| "Neuroblastoma is the most common solid tumour, accounting for about 30-50 per cent of tumours evident during the neonatal period." | ( Hartoov, J; Jaffa, AJ; Kupferminc, J; Many, A; Peyser, MR, 1993) |
| "Neuroblastomas are neural crest-derived tumors that contain neuronal, melanocyte, and Schwann cell precursors." | ( Dragunsky, E; Levenbook, I; Ridge, J; Terle, DA, 1996) |
| "Neuroblastoma is perhaps the most heterogeneous childhood cancer in terms of clinical behavior." | ( Dahbiová, R; Eckschlager, T; Hrusák, O; Jasinská, J; Kodet, R; Pilát, D; Stanková, J, 1996) |
| "Olfactory neuroblastoma is a rare malignancy of the olfactory mucosa that may be derived from the olfactory epithelium." | ( Gomez, G; Keane, WM; Lowry, LD; Rawson, N; Restrepo, D; Rothstein, JL, 1996) |
| "Neuroblastoma is a pediatric cancer for which a cure is elusive for most children with disseminated disease." | ( Benard, J; Eden, P; Prevost, G; Roubert, P; Roubert, V; Veber, N; Viollet, C, 1996) |
| "Melanoma, like neuroblastoma, is derived from the neural crest cell." | ( Kuzmanoff, KL; Ling-Indeck, L; Pezzuto, JM; Schmidt, ML, 1997) |
| "Human neuroblastoma is one of the most common solid tumors in infants and children and represents about 10% of all childhood cancers." | ( McLaughlin, PJ; Skitzki, J; Zagon, IS, 1999) |
| "Neuroblastoma is a childhood tumor of the peripheral nervous system that remains largely uncurable by conventional methods." | ( Feldman, EL; Van Golen, CM, 2000) |
| "Neuroblastoma is the most solid common extracranial malignancy in childhood." | ( Aronson, DC; Glick, RD; La Quaglia, MP; Medary, I; Scotto, KW; Swendeman, SL, 2000) |
| "Neuroblastoma is a childhood tumor that originates from the sympathetic nervous system." | ( Axelson, H; Grynfeld, A; Påhlman, S, 2000) |
| "Neuroblastoma is a common childhood cancer with a poor overall prognosis." | ( Butler, L; Coffey, DC; Glick, RD; Kutko, MC; LaQuaglia, MP; Marks, PA; Richon, VM; Rifkind, R; Swendeman, SL, 2000) |
| "Neuroblastoma is a solid tumor occurring usually in children less than 5 years old." | ( Chen, HR; Cheng, AT; Hsu, YP; Liu, YL, 2000) |
| "Neuroblastoma is the second most common solid malignancy of childhood." | ( Berg, PE; Eskenazi, AE; Fan, L; Frantz, CN; Frick, KK; Ikegaki, N; Iyer, J; Kennett, RH; Wada, RK; Zhu, S, 2001) |
| "Bone metastasis in neuroblastoma is an unfavorable prognostic factor even with intensive therapy." | ( Ihara-Watanabe, M; Michigami, T; Ozono, K; Yamazaki, M, 2001) |
| "Neuroblastomas are heterogeneous tumors arising from sympathetic precursors in the neural crest." | ( Baik, JC; Edgar, C; Eide, FF; Feng, X; Jiang, H, 2001) |
| "Neuroblastoma is the most common malignant solid cancers in early childhood." | ( Fujii, Y; Fukai, I; Kiriyama, M; Kondo, S; Sasaki, H; Sato, Y; Yamakawa, Y, 2001) |
| "Neuroblastoma is the most common extracranial solid tumor of childhood." | ( Bian, X; Castle, VP; Feng, Z; McAllister-Lucas, LM; Opipari, AW; Porter, AG; Schumacher, KR; Shao, F, 2001) |
| "Although neuroblastoma is a common tumor of early childhood, it is rare in adults." | ( Naito, K; Oba, K; Wada, T; Yamaguchi, S; Yoshihiro, S, 2001) |
| "Neuroblastoma is the most common type of cancer in infants." | ( Ariatta, C; Castino, R; Démoz, M; Gargiulo, M; Isidoro, C; Pace, D; Raiteri, E, 2002) |
| "Although neuroblastoma is the most common of extracranial solid tumors of childhood and infancy, we report the first case of an isolated neuroblastoma of a paranasal sinus." | ( Arndt, CA; Jenkins, RB; Passe, SM; Scheithauer, BW; Smith, JS; Strome, SE; Wei, JL, 2002) |
| "Neuroblastoma is the most common solid tumor of infants and children." | ( Chung, DH; Evers, BM; Hellmich, MR; Hu, W; Kelly, DR; Kim, S, 2002) |
| "Stage 4S neuroblastoma is an unusual malignancy that has an excellent prognosis, except in young infants." | ( Creamer, K; Flores, Y; Roberts, S; Robie, D; Shoupe, B, 2002) |
| "Neuroblastoma is a common childhood tumor derived from the peripheral nervous system." | ( Brodeur, GM; Camoratto, AM; Eggert, A; Evans, AE; Foster, P; Hishiki, T; Ho, R; Ikegaki, N; Minturn, JE, 2002) |
| "Neuroblastomas are the most common extracranial solid tumors of childhood." | ( Chung, DH; Evers, BM; Hu, W; Kang, J; Kim, S, 2003) |
| "Neuroblastoma is a highly heterogeneous tumor of young children." | ( Nowock, J; Schwab, M; Westermann, F; Wiedemeyer, R; Wittke, I, 2003) |
| "Neuroblastoma is a common pediatric tumor of the sympathetic nervous system." | ( Fujii, Y; Haruki, N; Kobayashi, Y; Kondo, S; Sasaki, H; Sato, Y; Toyama, T, 2003) |
| "Neuroblastoma is a frequent tumor of childhood and remains a leading cause of death despite treatment intensification." | ( Bischof Delaloye, A; Boubaker, A, 2003) |
| "Neuroblastoma is a childhood tumor thought to arise through improper differentiation of neural crest cells." | ( Feldman, EL; Grauman, AR; Soules, ME; van Golen, CM, 2003) |
| "Neuroblastoma is the second most common solid tumor in childhood and frequently metastasizes to the bone marrow and the bone matrix." | ( DeClerck, YA; Pollack, H; Reynolds, CP; Scadeng, M; Shimada, H; Sohara, Y; Yamada, S; Ye, W, 2003) |
| "Neuroblastoma is the most frequent solid tumor of the abdomen of childhood, yet children with this disease frequently have metastases at presentation." | ( Beck, L; Frischer, JS; Huang, J; Kadenhe-Chiweshe, A; Kaicker, S; Kandel, JJ; McCrudden, KW; New, T; Serur, A; Yamashiro, DJ; Yokoi, A, 2003) |
| "Neuroblastoma is the most common solid tumour in childhood." | ( Cañete, A; Castel, V, 2004) |
| "Neuroblastoma is one of common solid tumors in children." | ( Chen, XQ; He, YJ; Lin, TY; Liu, DG; Su, YS; Sun, XF, 2003) |
| "Neuroblastomas are the most frequently occurring solid tumors in children under 5 years." | ( van Noesel, MM; Versteeg, R, 2004) |
| "Neuroblastoma is a heterogeneous tumor consisting of N (neuronal) and S (stromal) cells." | ( Feldman, EL; Kim, B; van Golen, CM, 2004) |
| "Neuroblastoma is a very rare tumor in adult patients." | ( Dölken, G; Fiedler, W; Lorenz, G; Stockschläder, M; Sucker, C, 2004) |
| "More aggressive neuroblastomas are generally immature and overexpression of exogenous MYCN in cultured neuroblastoma cells and other neuronal cell types has been reported to inhibit induced differentiation, suggesting a link between high MYCN expression and an immature phenotype." | ( Culp, LA; Edsjö, A; Karlsson, J; Nilsson, H; Påhlman, S; Pattyn, F; Speleman, F; Vandesompele, J, 2004) |
| "Neuroblastoma is the most common solid tumor of infancy and is believed to result from impaired differentiation of neuronal crest embryonal cells." | ( Bloch, DB; Bloch, KD; Diller, LR; Nakajima, A; Nakajima, H; Yu, JH, 2004) |
| "Neuroblastoma is a childhood tumor originating from cells of the developing sympathetic nervous system." | ( Axelson, H, 2004) |
| "Neuroblastoma is a childhood cancer arising from the sympathetic nervous system." | ( Caron, HN; de Ruijter, AJ; Kaufmann, JO; Kemp, S; Kramer, G; Meinsma, RJ; van Kuilenburg, AB, 2004) |
| "The childhood tumor neuroblastoma is characterized by N-myc amplification in aggressive and highly proliferative tumors that occur in a subset of patients." | ( Carroll, WL; Kim, MK, 2004) |
| "Neuroblastoma is the single most common and deadly tumor of childhood and is often associated with therapy resistance." | ( Elfman, L; Johnsen, JI; Kogner, P; Lindskog, M; Orrego, A; Pettersen, I; Ponthan, F; Sveinbjörnsson, B, 2004) |
| "Neuroblastoma is a childhood cancer, which spontaneously regresses." | ( Emmans, VC; Hunt, AN; Lillycrop, KA; Rodway, HA, 2004) |
| "Neuroblastoma is the commonest extracranial solid tumor of childhood and frequently metastasizes to the bone." | ( Boos, J; Lanvers-Kaminsky, C; Vorotnjak, M, 2004) |
| "Neuroblastoma is an extremely malignant solid tumor in children, characterized by spontaneous differentiation and regression." | ( Chen, CM; Chuang, JH; Hsiao, CC; Huang, CC; Huang, LL; Sheen, JM; Tai, MH, 2005) |
| "Neuroblastoma is the most common extracranial solid tumor of children that arises from the sympathetic nervous system." | ( Bosco, MC; Melillo, G; Pastorino, S; Pezzolo, A; Puppo, M; Varesio, L, 2004) |
| "Neuroblastoma is derived from SNS precursors." | ( Beckman, S; Harris, AL; Jögi, A; Nilsson, H; Påhlman, S; Poellinger, L, 2005) |
| "Neuroblastoma is a pediatric tumor accounting for 15% of childhood cancer deaths and has a poor prognosis in children >1 year of age." | ( Kaplan, DR; Lavoie, JF; Torkin, R; Yeger, H, 2005) |
| "Neuroblastoma is the second most common pediatric malignancy, characterized by a high rate of unexplained spontaneous remissions." | ( Evangelopoulos, ME; Krüttgen, A; Weis, J, 2005) |
| "Neuroblastoma is the most common extracranial solid tumor in children." | ( Buoncompagni, A; Caruso, U; De Bernardi, B; Deiana, F; Levreri, I; Marchese, N; Melioli, G, 2005) |
| "Neuroblastoma is highly sensitive to gemcitabine." | ( Hori, H; Komada, Y; Miyahara, M; Ogawa, M; Ohta, T; Onozato, K, 2005) |
| "Neuroblastoma is the most frequent extracranial solid malignancy of childhood with a high mortality in advanced tumour stages." | ( Eggert, A; Hecht, M; Schulte, JH; Schweigerer, L; Wilting, J, 2005) |
| "Neuroblastoma is a childhood tumor with a poor survival in advanced stage disease despite intensive chemotherapeutic regimes." | ( Bosma, P; Caron, HN; de Ruijter, AJ; Kemp, S; Meinsma, RJ; van Kuilenburg, AB, 2005) |
| "Neuroblastoma is one of the most common extracranial solid tumours in childhood with a poor prognosis in its advanced stage." | ( Barone, G; Carminati, P; D'Incalci, M; Di Francesco, AM; Frapolli, R; Meco, D; Pisano, C; Riccardi, A; Riccardi, AS; Riccardi, R; Rutella, S; Zucchetti, M, 2005) |
| "Neuroblastoma is a tumour derived from primitive cells of the sympathetic nervous system and is the most common extracranial solid tumour in childhood." | ( Binz, N; Grotzer, MA; Rivera, P; Shalaby, T; Shin-ya, K, 2005) |
| "Neuroblastoma is a common solid tumor of childhood that is derived from the neural crest." | ( Brodeur, GM; Cnaan, A; Evans, AE; Hishiki, T; Ho, R; Maris, J; Minturn, JE; Wang, Q; Zhao, H, 2005) |
| "Neuroblastoma is a heterogeneous neural crest-derived embryonic childhood neoplasm that is the second most common solid tumor found in children." | ( Auderset, K; Bourloud, KB; Delattre, O; Fattet, S; Flahaut, M; Gross, N; Joseph, JM; Martinet, D; Meier, R; Mühlethaler-Mottet, A; Schmutz, NB, 2006) |
| "Neuroblastoma is the most common solid tumor of infants and carries a poor prognosis especially in advanced stages." | ( Parashar, B; Shafit-Zagardo, B, 2006) |
| "Neuroblastoma is a heterogeneous pediatric disease." | ( Couturier, J; de Cremoux, P; Delattre, O; Doz, F; Fehlbaum, P; Jourdan-Da-Silva, N; Klijanienko, J; Michon, J; Mosseri, V; Schleiermacher, G; Tran-Perennou, C; Vielh, P, 2007) |
| "Neuroblastoma is the most common extracranial childhood tumor." | ( Aumailley, M; Becker, J; Erdlenbruch, B; Noskova, I; Schorderet, DF; Schramm, A; Schweigerer, L, 2006) |
| "Neuroblastoma is unique in that activation of the PI3K/Akt pathway is either not essential to its TRAIL resistance or counteracted because of the multiple repetitive pathways of TRAIL resistance." | ( Beierle, EA; Chen, MK; Dai, W; Efron, PA; Iyengar, M; Nagaram, A, 2006) |
| "Neuroblastoma is a common solid tumor of children that arises from the sympathetic nervous system." | ( Aoki, S; Hosoi, H; Izumi, M; Kamiyama, J; Kobayashi, M; Sakai, T; Sowa, Y; Sugimoto, T; Takahara, Y; Watanabe, H; Yogosawa, S, 2006) |
| "Neuroblastoma is the most common extracranial solid tumor in children causing death at pre-school age, as no cure has yet been developed." | ( Banik, NL; Das, A; Ray, SK, 2006) |
| "Stage 4S neuroblastoma is a special tumor that carries excellent prognosis." | ( Al-Asaad, TG; Al-Sulami, GA; Atra, AA; Elimam, NA; Fayea, NY; Felimban, SK; Khattab, TM, 2006) |
| "Neuroblastoma is sensitive to IGF." | ( Dominici, C; Mancini, C; Mancuso, M; McDowell, HP; Raschellà, G; Tanno, B; Vitali, R, 2006) |
| "Neuroblastomas are pediatric tumors of sympathetic origin, expressing neuronal markers, such as NPY and its receptors." | ( Kitlinska, J, 2007) |
| "Neuroblastoma is the most common extracranial solid tumor of childhood, and iodine-131-metaiodobenzylguanidine (MIBG) therapy is a new approach for grade IV neuroblastoma." | ( Aoyama, C; Hosoya, R; Kamiya, T; Kato, I; Manabe, A; Ogawa, C; Ozawa, M; Takahashi, H; Takusagawa, A; Yokoyama, K, 2008) |
| "Neuroblastoma is the most common solid tumour in infants characterized by a high resistance to apoptosis." | ( Ceña, V; Posadas, I; Prieto-Lloret, J; Santos, P; Vellecco, V, 2007) |
| "Neuroblastoma is the most common and deadly solid tumor of childhood." | ( Eksborg, S; Fuskevåg, OM; Gleissman, H; Johnsen, JI; Kogner, P; Ponthan, F; Redfern, CP; Segerström, L; Sveinbjörnsson, B; Wickström, M, 2007) |
| "Neuroblastoma is one of the main causes of children's deaths in Japan and many developed countries, although it is a rather rare pediatric cancer." | ( Fukushima, T; Kumagai, M; Shichino, H, 2007) |
| "Neuroblastomas are pediatric tumors originating from immature neuroblasts in the developing peripheral nervous system." | ( Benedetti, E; Cerù, MP; Cifone, MG; Cimini, A; Cinque, B; Cristiano, L; D'Amico, MA; D'Angelo, B; Di Loreto, S; Festuccia, C, 2007) |
| "Neuroblastoma is a common pediatric malignancy that metastasizes to the liver, bone, and other organs." | ( Chesler, L; Gable, K; Goldenberg, DD; Goldfine, ID; Liu, D; Maddux, BA; Matthay, KK; Meyer, GE; Rosenthal, SM; Weiss, WA; Youngren, JF, 2007) |
| "Neuroblastoma is the most common extracranial solid malignancy in children." | ( Dyer, SA; Edwards, EC; Grundy, RG; Levine, BA; McConville, C; McMullan, DJ; Peet, AC; Reed, M; Strachan, MC; Wilkes, TM; Wilson, M, 2007) |
| "Neuroblastoma is the most common extracranial solid tumor in childhood." | ( Albert, DM; Bhattacharya, S; Chow, CC; Darjatmoko, S; Kulkarni, AD; Lindstrom, MJ; Lokken, J; Marcet, MM; van Ginkel, PR; Yang, W, 2007) |
| "Neuroblastoma is a malignant solid tumor of children, which derives from the embryonal sympathoadrenal linage." | ( Higashi, M; Kinoshita, Y; Maehara, Y; Souzaki, R; Suita, S; Taguchi, T; Tajiri, T; Tatsuta, K, 2007) |
| "Neuroblastoma is an aggressive childhood disease of the sympathetic nervous system." | ( Albert, DM; Darjatmoko, SR; Kulkarni, A; Lindstrom, MJ; Polans, AS; Sareen, D; Subramanian, L; van Ginkel, PR; Walker, Q, 2007) |
| "Neuroblastoma is the most common extracranial solid tumor of childhood." | ( Gullbo, J; Johnsen, JI; Kogner, P; Larsson, R; Lewensohn, R; Lindskog, M; Lövborg, H; Ponthan, F; Segerström, L; Sveinbjörnsson, B; Viktorsson, K; Wickström, M, 2007) |
| "Neuroblastoma is one of the most common cancers in children." | ( Benjelloun, FD; Corbière, C; Delaune, A; Legrand, E; Ripoll, C; Vannier, JP; Vasse, M, 2008) |
| "Dumbbell neuroblastomas are now considered to be unresectable tumors and preoperative chemotherapy is recommended." | ( Benachi, A; Delahaye, S; Doz, F; Mitanchez, D; Saada, J; Sarnacki, S; Sonigo, P, 2008) |
| "Neuroblastoma is the most frequent solid malignancy of children." | ( Becker, J; Noskova, I; Schramm, A; Schweigerer, LL; Volland, S; Wilting, J, 2008) |
| "Neuroblastoma is the second most common solid tumour during childhood, characterized by rapid disease progression." | ( Bardenheuer, W; Díaz-Carballo, D; Freistuehler, M; Malak, S; Reusch, HP, 2008) |
| "Neuroblastoma is a severe pediatric tumor, histologically characterised by a variety of cellular phenotypes." | ( Caccia, C; Florian, MC; Maggi, R; Messi, E; Zanisi, M, 2008) |
| "Neuroblastoma is one of the most devastating pediatric solid tumors and is unresponsive to many interventions." | ( Beierle, EA; Cance, WG; Golubovskaya, VM; Kurenova, EV; Nagaram, A; Trujillo, A, 2008) |
| "Neuroblastoma is the most common solid tumor in children." | ( Abiko, Y; Akihisa, T; Kimura, Y; Motani, K; Nagai, H; Okano, S; Shibata, Y; Suzuki, T; Tabata, K, 2008) |
| "Neuroblastomas are characterized by hemizygous 1p deletions, suggesting that a tumor suppressor gene resides in this region." | ( Brodeur, GM; Fujita, T; Gotoh, T; Igarashi, J; Kim, J; Kolla, V; London, WB; Manne, J; Maris, JM; Okawa, ER; Pawel, BR; White, PS; Zhao, H, 2008) |
| "Neuroblastoma is the most common pediatric extracranial solid cancer." | ( DuBois, SG; Matthay, KK, 2008) |
| "Neuroblastoma is the most common solid tumor of childhood." | ( Adil, A; Benchkroun, S; Boulaajaj, FZ; Bourezgui, M; El Moutawakkil, B; Kadiri, R; Lezar, S; Rafai, MA; Sibai, M; Slassi, I, 2008) |
| "Neuroblastoma is a pediatric tumor which can spontaneously regress or differentiate into a benign tumor." | ( Chadéneau, C; Chevrier, L; Cochaud, S; Meunier, AC; Muller, JM, 2008) |
| "Chemoresistance in neuroblastoma is a significant issue complicating treatment of this common pediatric solid tumor." | ( Chesler, L; Collins, R; Goldenberg, DD; Grimmer, M; Kim, GE; Matthay, KK; Nguyen, K; Tihan, T; Weiss, WA; Yakovenko, S, 2008) |
| "Neuroblastoma is the most common childhood cancer, which arises from sympathetic neural precursors." | ( Akamizu, T; Ariyasu, H; Hosoda, K; Iwakura, H; Kanamoto, N; Kangawa, K; Nakao, K, 2008) |
| "Neuroblastoma is a frequently lethal childhood tumor in which MYC gene deregulation, commonly as MYCN amplification, portends poor outcome." | ( Buxton, A; Cheng, NC; Davis, K; Evageliou, NF; Gilmour, SK; Guo, R; Haber, M; Hayes, CS; Hogarty, MD; Keating, J; Liu, X; London, WB; Marshall, GM; Murray, J; Norris, MD; Pawel, B; Sekyere, E; Smith, J; Sutton, R; Thomas, W; Venn, N; Zhao, H, 2008) |
| "Although the neuroblastoma is usually differentiated by all-trans-retinoic acid (RA), both RA-differentiated and undifferentiated SH-SY5Y cells have been used in neuroscience research." | ( Chang, RC; Cheung, YT; Lai, CS; Lau, WK; So, KF; Yeung, SC; Yu, MS, 2009) |
| "Neuroblastoma is an embryonic tumor of the peripheral sympathetic nervous system, and is able to take up, store and secrete catecholamine metabolites." | ( Dubois, S; Matthay, KK; Taggart, D, 2008) |
| "Neuroblastoma is a pediatric malignancy that arises from the neural crest, and patients with high-risk neuroblastoma, which typically harbor amplifications of MYCN, have an extremely poor prognosis." | ( Cleveland, JL; Fallahi, M; Hall, MA; Li, W; Rounbehler, RJ; Yang, C, 2009) |
| "High-risk neuroblastoma is characterized by poor survival rates, and the development of improved therapeutic approaches is a priority." | ( Boddy, AV; Castelbuono, DJ; Clifford, SC; Curtin, NJ; Daniel, RA; Drew, Y; Hostomsky, Z; Mulligan, EA; Plummer, ER; Rozanska, AL; Thomas, HD; Tweddle, DA, 2009) |
| "Human malignant neuroblastoma is characterized by poor differentiation and uncontrolled proliferation of immature neuroblasts." | ( Banik, NL; Das, A; Ray, SK, 2009) |
| "Neuroblastoma is the most common extracranial solid tumor in children and, when disseminated, carries a poor prognosis." | ( Ashikaga, T; Bosenberg, M; Brard, L; Dorf, L; Illeyne, S; Kalkunte, S; Koto, K; Nishi, R; Saulnier Sholler, GL; Straub, JA, 2009) |
| "Neuroblastoma is a pediatric extracranial tumor and a major cause of death in children under age 2." | ( Banik, NL; Choudhury, SR; Karmakar, S; Mohan, N; Ray, SK, 2009) |
| "Neuroblastomas are childhood tumors with an often lethal outcome." | ( Caron, HN; Ebus, ME; Geerts, D; Koster, J; Lamers, F; Molenaar, JJ; Valentijn, LJ; Versteeg, R; Westerhout, EM, 2009) |
| "Neuroblastoma is the childhood malignancy that mainly occurs in adrenal glands and is found also in the neck, chest, abdomen, and pelvis." | ( Banik, NL; Choudhury, SR; Karmakar, S; Ray, SK, 2009) |
| "Neuroblastoma is an important pediatric tumor in which Myc-N amplification is a well-known poor prognostic indicator." | ( Aktas, S; Altun, Z; Aygun, N; Erbayraktar, Z; Olgun, N, 2010) |
| "Neuroblastoma is the most common extracranial solid tumor in infants and young children." | ( Banik, NL; Choudhury, SR; Davis, KA; Deeconda, A; Karmakar, S; Ray, SK, 2009) |
| "Neuroblastoma is a pediatric solid tumor that exhibits striking clinical bipolarity." | ( Hicks, SL; Ikegaki, N; Kung, B; Tang, XX; Zhao, H, 2009) |
| "Neuroblastoma is an extracranial, solid, and heterogeneous malignancy in children." | ( Banik, NL; Karmakar, S; Ray, SK; Roy Choudhury, S, 2010) |
| "The esthesioneuroblastoma is a rare neuroendocrine tumor that derives from the olfactory cells." | ( Biamonte, R; Ceniti, S; Conforti, S; De Simone, R; Filice, A; Liguori, V; Manfredi, C; Mastroianni, C; Palazzo, S; Patitucci, G; Rovito, A; Turano, S; Viscomi, C, 2010) |
| "Neuroblastoma is a pediatric tumor of neural crest cells that is clinically characterized by its variable evolution, from spontaneous regression to malignancy." | ( Barrette, S; Béliveau, R; Gingras, D; Nyalendo, C; Ohta, S; Sartelet, H, 2009) |
| "Neuroblastoma is the most frequent extracranial solid tumor in children." | ( Ausserlechner, MJ; Bodner, M; David, R; Geiger, K; Hagenbuchner, J; Meister, B; Obexer, P; Porto, V; Villunger, A, 2010) |
| "Neuroblastoma is the third most common malignancy of childhood." | ( El-Maghraby, T, 2007) |
| "Neuroblastoma is a pediatric tumor that is thought to arise from autonomic precursors in the neural crest." | ( del Pino, I; Majdazari, A; Reiff, T; Rohrer, H; Schmidt, M; Tsarovina, K, 2010) |
| "High-risk neuroblastoma is a rapidly growing tumor with a survival rate below 50%." | ( Azarbayjani, F; Christofferson, R; Eriksson, S; Fuchs, D; Rodriguez, A; Sundberg, C, 2010) |
| "Neuroblastoma is a pediatric malignancy characterized by tremendous clinical heterogeneity, in which some tumors are extremely aggressive while others spontaneously differentiate into benign forms." | ( Cao, L; Keung, AJ; Kumar, S; Lam, WA; Sen, S; Umesh, V, 2010) |
| "Neuroblastoma is a sympathetic nervous system tumour whose degree of malignancy, prognosis and therapy resistance has been associated with the amplification of MYCN oncogene." | ( Almeida, A; Bolaños, JP; Cuende, J; Delgado-Esteban, M; Veas-Perez de Tudela, M, 2010) |
| "Neuroblastoma is the first pediatric cancer for which monoclonal-antibody-based immunotherapy has been shown to be effective, particularly for metastatic osteomedullary disease." | ( Cheung, NK; Modak, S, 2010) |
| "Neuroblastoma is an embryonic tumour of the sympathetic nervous system, metastatic in half of the patients at diagnosis, with a high preponderance of osteomedullary disease, making accurate evaluation of metastatic sites and response to therapy challenging." | ( Cohn, SL; Giammarile, F; Ladenstein, R; Lewington, V; Matthay, KK; Michon, J; Pearson, AD; Shulkin, B, 2010) |
| "Neuroblastoma is a common solid tumor in children and its tumorigenicity is enhanced by the expression of survival pathways such as Akt and signal transducer and activator of transcription 3 (STAT3)." | ( Brown, RE; Chai, H; Luo, AZ; Weerasinghe, P, 2010) |
| "Neuroblastoma is a tumour originating from neuronal precursor cells, and, although the molecular basis of its progression is still poorly understood, the implication of L1 activation has not yet been investigated." | ( Capri, M; Del Re, B; Giorgi, G; Marcantonio, P, 2010) |
| "Neuroblastomas are pediatric tumors that develop from sympathetic precursors and express neuronal proteins, such as neuropeptide Y (NPY)." | ( Abe, K; Everhart, L; Jönsson-Rylander, AC; Kitlinska, J; Kuan-Celarier, A; Kuo, L; Li, L; Lu, C; Munivenkatappa, RB; Sun, CC; Sun, J; Tilan, J; Toretsky, JA; Zukowska, Z, 2010) |
| "Treatment of neuroblastoma is successful in less than half of patients with high-risk disease." | ( Becherini, P; Cilli, M; Emionite, L; Greenberger, LM; Horak, ID; Loi, M; Pastorino, F; Ponzoni, M; Ribatti, D; Sapra, P, 2010) |
| "High-risk neuroblastoma is a severe pediatric tumor characterized by poor prognosis." | ( Bettinsoli, P; Bonini, SA; Buizza, L; Facchetti, F; Ferrari-Toninelli, G; Memo, M; Poliani, PL; Uberti, D, 2010) |
| "Neuroblastoma is a highly malignant neoplasm found in young children." | ( Alm, K; Holst, CM; Oredsson, SM; Söderstjerna, E, 2010) |
| "Neuroblastoma is a childhood malignancy of the sympathetic nervous system." | ( Edo, R; Ikegaki, N; Jeng, EI; Leonhardt, P; Rappaport, EF; Regan, PL; Tang, XX; Torres, J, 2010) |
| "Neuroblastoma is a common childhood tumor derived from neural crest precursor cells." | ( Aoyama, M; Asai, K; Kataoka, H; Kubota, E; Tada, T, 2010) |
| "The neuroblastoma is an embryonic tumor of the peripheral sympathetic nervous system, and is metastatic or otherwise high risk for relapse in nearly 50% of cases, with a long-term survival of <40%." | ( Coppenrath, E; Pflüger, T; Schmid, I; Weiss, M, 2010) |
| "Neuroblastoma is the most common paediatric extra cranial solid cancer characterized by meta-iodobenzylguanidine (mIBG) avidity in >/=90% of patients." | ( Baum, RP; Howman-Giles, R; Schmidt, M; Simon, T, 2010) |
| "Neuroblastoma is an often fatal pediatric cancer arising from precursor cells of the sympathetic nervous system." | ( Bray, I; Bryan, K; Buckley, PG; Das, S; Foley, N; Murphy, DM; Stallings, RL; Watters, KM, 2010) |
| "Neuroblastoma is the foremost malignant neoplasm of the fetus and neonate." | ( Alvir-Alvaro, A; Campillos-Maza, JM; Crespo-Esteras, R; Tobajas-Homs, JJ, 2010) |
| "Neuroblastoma is a childhood cancer that exhibits either a favorable or an unfavorable phenotype." | ( Edo, R; Friedmann, J; Jacobs, J; Regan, PL; Tang, XX; Torres, J; Wang, G, 2011) |
| "Neuroblastoma is one of the most aggressive solid tumors in the childhood." | ( Bernardini, S; D'Aguanno, S; D'Alessandro, A; De Canio, M; Federici, G; Marzano, V; Pieroni, L; Roveri, A; Urbani, A; Zaccarin, M, 2011) |
| "In childhood, neuroblastoma is the most common GD2-expressing tumour." | ( Cañete, A; Castel, V; Segura, V, 2010) |
| "Neuroblastoma is the most common extracranial solid tumor of childhood." | ( Dickey, A; Hallahan, D; Hu, R; Leahy, K; Schleicher, S; Thotala, DK, 2011) |
| "Neuroblastoma is a common childhood cancer that often results in progressive minimal residual disease after primary tumor resection." | ( Intra, J; Salem, AK; Sandler, AD; Williams, RL; Zhang, XQ; Zhu, X, 2011) |
| "Neuroblastoma is the most common extracranial solid malignancy in children but rarely described in adults, being 10% of all cases diagnosed after the first decade of life." | ( Ferreti Bonan, PR; Martelli-Júnior, H; Miranda Soares, PB; Pereira DE Souza, W; Quirino Filho, S, 2010) |
| "Neuroblastoma is a type of pediatric cancer." | ( De Ciucis, C; Domenicotti, C; Marengo, B; Marinari, UM; Nitti, M; Passalacqua, M; Pronzato, MA; Ricciarelli, R; Zingg, JM, 2011) |
| "Malignant neuroblastomas are solid tumors in children." | ( Banik, NL; Karmakar, S; Mohan, N; Ray, SK, 2011) |
| "Neuroblastoma is the most common pediatric abdominal tumor and principally a p53 wild-type, highly vascular, aggressive tumor, with limited response to anti-VEGF therapies alone." | ( Barbieri, E; Chen, Z; Diaz-Miron, J; Gao, D; Johnson, BA; Kim, ES; Ludwig, A; Patterson, DM; Shohet, JM; Trahan, DN; Vassilev, L, 2011) |
| "Neuroblastoma is the most common pediatric extracranial solid cancer." | ( Carpentier, P; Cougnenc, O; Défachelles, AS, 2011) |
| "Neuroblastoma is a solid tumor of the sympathetic nervous system accounting for up to 10% of pediatric cancers and 15% of cancer-related deaths." | ( Cui, HJ; Cui, ZB; Ke, XX; Li, FF; Li, T; Tan, J; Wang, XW, 2011) |
| "Neuroblastoma is a malignant pediatric tumor with poor survival." | ( Beaunoyer, M; Castaing, M; Duval, M; Fabre, M; Fetni, R; Michiels, S; Rougemont, AL; Sartelet, H; Vassal, G, 2011) |
| "Neuroblastoma is the most common extracranial solid tumour in childhood (8% of all childhood cancers), the most frequently diagnosed in infancy, and has one of the highest death rates, while chromaffin tumours rarely present in childhood." | ( Carachi, R; Davidson, DF; Hammond, PJ; Murphy, D, 2011) |
| "Neuroblastoma is the most common pediatric extracranial soft-tissue tumor, accounting for approximately 8% of childhood malignancies." | ( Gelfand, MJ; Sharp, SE; Shulkin, BL, 2011) |
| "Neuroblastoma is the most prevalent extracranial solid tumor mainly in pediatric patients." | ( Banik, NL; Mohan, N; Ray, SK, 2011) |
| "Neuroblastoma is one of the most common solid tumours in children (8-10% of all malignancies)." | ( Cui, H; Cui, ZB; Gong, XY; Hao, XW; Ke, XX; Li, T; Wan, JH; Wang, L; Xiang, Z; Xu, M, 2012) |
| "Neuroblastoma is the most common extra-cranial solid tumor in children." | ( Chen, SY; Cheng, YF; Li, WJ; Ma, Y; Zhang, Q; Zhang, Z, 2011) |
| "Neuroblastoma is a common solid tumor of childhood and advanced disease carries a poor prognosis despite intensive multimodality therapy." | ( Brandenburg, M; Dive, C; Klymenko, T; Makin, G; Morrow, C, 2011) |
| "Neuroblastoma are pediatric tumors that belong to the group of small round blue cell tumors, characterized by a fast proliferation." | ( Caron, HN; de Preter, K; Ebus, ME; Gisselsson, D; Koster, J; Molenaar, JJ; Speleman, F; van Sluis, P; Versteeg, R; Westerhout, EM; Øra, I, 2012) |
| "Neuroblastoma is the most common extracranial and deadly solid tumor in children." | ( Abdel Rahman, H; El Debawy, E; Ezzat, S; Mostafa, NE; Moussa, EA; Rayan, Ael R; Yones, A; Zekri, WZ, 2011) |
| "Neuroblastoma is a common embryonal malignancy in which high-stage cases have a poor prognosis, often associated with resistance to chemotherapeutic drugs." | ( Brown, KW; Charlet, J; Diederich, M; Schnekenburger, M, 2012) |
| "Neuroblastoma is a neural crest-derived embryonal tumour of the postganglionic sympathetic nervous system and a disease with several different chromosomal gains and losses, which include MYCN-amplified neuroblastoma on chromosome 2, deletions of parts of the chromosomes 1p and 11q, gain of parts of 17q and triploidy." | ( Christensen, JG; Combaret, V; Djos, A; Hallberg, B; Kamaraj, S; Martinsson, T; Palmer, RH; Ruuth, K; Schönherr, C; Wang, CL; Yang, HL, 2012) |
| "Neuroblastoma is an embryonic malignancy arising from neuroblasts." | ( Gong, G; Hu, D; Hu, Y; Xu, Y; Yang, Y; Zhi, F; Zhu, Y, 2012) |
| "Neuroblastoma is a major childhood cancer arising from precursor cells of the sympathetic nervous system which is known to acquire deletions and alterations in the expression patterns of PTPRD, indicating a potential tumor suppressor function for this gene." | ( Chan, TA; Fabius, AW; Foley, N; Jefferies, CA; Lazzari, E; Meehan, M; Moran, N; Murphy, D; Ortiz, B; Parthasarathi, L; Ryan, J; Stallings, RL, 2012) |
| "Neuroblastomas are the most common extracranial solid tumors in children." | ( Bhaskara, VK; Mohanam, I; Mohanam, S; Rao, JS, 2012) |
| " Neuroblastoma is a frequent childhood cancer with a heterogeneous prognosis." | ( Alexendrov, L; Annabi, B; Duval, M; Fabre, M; Fetni, R; Haddad, E; Imbriglio, T; Nyalendo, C; Sartelet, H; Sinnett, D; Vassal, G; Victor, K, 2012) |
| "Neuroblastoma is the most common extracranial solid tumor in the pediatric population." | ( Ara, T; Buettner, R; DeClerck, YA; Jove, R; Jove, V; Nam, S; Seeger, R; Wang, Y; Wu, J; Xin, H; Xu, Y; Yang, F; Yu, H, 2012) |
| "Neuroblastoma is a common childhood malignant tumor originated from the neural crest-derived sympathetic nervous system." | ( Li, X; Liu, H; Mei, Y; Wang, Z; Ye, J; You, H; Zhang, L; Zhang, Y, 2012) |
| "Malignant neuroblastomas are childhood tumors that remain mostly incurable." | ( Banik, NL; Chakrabarti, M; Khandkar, M; Ray, SK, 2012) |
| "Neuroblastoma is a solid tumor that mostly occurs in children." | ( Banik, NL; Hossain, MM; Ray, SK, 2012) |
| "Most of the neuroblastomas are sporadic but some are familial." | ( Bhatnagar, SN; Sarin, YK, 2012) |
| "Neuroblastoma is a common pediatric tumor characterized by clinical heterogeneity." | ( Brodeur, GM; Brown, JL; Evans, AE; Ho, R; Iyer, R; Light, JE; Minturn, JE; Simpson, AM; Thress, K; Varela, CR; Zhao, H, 2012) |
| "Neuroblastoma is one of the most challenging malignancies of childhood, being associated with the highest death rate in paediatric oncology, underlining the need for novel therapeutic approaches." | ( Bray, IM; Davidoff, AM; Domingo-Fernández, R; Gubala, V; Harvey, H; Lode, HN; McDonagh, C; Ng, CY; Nooney, R; Orr, WS; Piskareva, O; Prenter, S; Stallings, RL; Tivnan, A; Williams, DE, 2012) |
| "Neuroblastoma is the most common pediatric solid extracranial malignancy." | ( Chen, Y; Tsai, YH; Tseng, SH, 2013) |
| "Neuroblastoma is the most common solid tumor in children." | ( Alimoghaddam, K; Behmanesh, M; Ghaffari, SH; Ghavamzadeh, A; Momeny, M; Nafissi, S; Soltani, BM; Yousefi, M; Zekri, A, 2012) |
| "Neuroblastoma is the most common extracranial solid tumor of childhood." | ( Cao, G; He, J; Joshi, HC; Li, S; Tang, S; Tong, Q, 2012) |
| "Neuroblastoma is the most common solid tumor in infancy." | ( Buck, SA; Lyman, WD; Vangipuram, SD, 2012) |
| "Neuroblastoma is a common childhood neoplasia arising from neurogenic tissues." | ( Karayalcin, B; Koç, ZP, 2012) |
| "Neuroblastoma is the most common extracranial solid tumor in children that is refractory to intensive multimodal therapy." | ( Demachi-Okamura, A; Fujita, M; Hirosawa, T; Kojima, S; Kuzushima, K; Maki, H; Nishio, N; Taguchi, O; Takahashi, Y; Tanaka, Y; Uemura, Y; Zhang, R, 2012) |
| "Neuroblastoma is a childhood extracranial solid tumour that is associated with a number of genetic changes." | ( Attiyeh, EF; Chand, D; Hallberg, B; Kogner, P; Maris, J; Marra, MA; Martinsson, T; Morozova, O; Nakagawara, A; Ohira, M; Palmer, RH; Ruuth, K; Sandström, PE; Schönherr, C; Yamazaki, Y, 2013) |
| "Neuroblastoma is the most common extracranial solid tumor found in infancy and childhood." | ( Leung, KN; Liao, XM, 2013) |
| "Neuroblastoma is a severe pediatric tumor characterized by poor prognosis." | ( Ayla, S; Bilir, A; Ergüven, M; Oktem, G; Soner, BC; Yilmaz-Dilsiz, O, 2014) |
| "Neuroblastoma is a common childhood tumor." | ( Cheng, S; Sun, H; Tu, Y; Xu, Z; Zhang, S, 2013) |
| "Neuroblastoma is uniquely sensitive to single-agent inhibition of the DNA damage checkpoint kinase Chk1, leading us to examine downstream effectors of this pathway and identify mitotic regulator Wee1 as an additional therapeutic target in this disease." | ( Belcastro, L; Cole, KA; Levin, K; Li, Y; Maris, JM; Martinez, D; Pawel, B; Rader, J; Russell, MR; Shumway, SD, 2013) |
| "Neuroblastoma is one of the most commonly encountered solid tumors in the pediatric age group, and the prognosis of patients with advanced neuroblastoma is very poor." | ( Kim, M; Makino, M; Satoh, M; Satoh, Y; Suzuki, T; Tabata, K, 2012) |
| "Neuroblastoma is a common, frequently fatal, neural crest tumor of childhood." | ( Ashton, J; Ganeshan, V; Schor, NF, 2013) |
| "Neuroblastoma is a childhood tumor that arises from immature neuroblasts of the sympathetic nervous system." | ( Ai, W; Banik, NL; Chakrabarti, M; Mohan, N; Ray, SK, 2013) |
| "Neuroblastoma is a rare childhood cancer whose high risk, metastatic form has a dismal outcome in spite of aggressive therapeutic interventions." | ( Anderson, J; Cantilena, S; Chayka, O; D'Alicarnasso, M; Himoudi, N; Morgenstern, DA; Pearson, K; Piotrowska, I; Sala, A; Santilli, G; Thrasher, AJ, 2013) |
| "Neuroblastoma is a pediatric tumor of the peripheral sympathetic nervous system with a highly variable prognosis." | ( Koster, J; Santo, EE; Sluis, PV; Stroeken, P; Versteeg, R; Westerhout, EM, 2013) |
| "Neuroblastoma is an aggressive childhood disease of the sympathetic nervous system." | ( Kataria, H; Kaul, SC; Kaur, G; Wadhwa, R, 2013) |
| "Neuroblastoma is an embryonic tumor derived from cells of the neural crest." | ( de Torres, C; Ferronha, T; Gil-Guiñon, E; Le Dréau, G; Martí, E; Rabadán, MA, 2013) |
| "Neuroblastoma is the most common solid tumor in childhood and represents 15% of all children's cancer deaths." | ( Bell, JL; Cheung, BB; Kavallaris, M; Malyukova, A; Marshall, GM, 2013) |
| "Neuroblastoma is an aggressive pediatric malignancy with significant chemotherapeutic resistance." | ( Banerjee, S; Dudeja, V; Krosch, TC; Mujumdar, N; Saluja, AK; Sangwan, V; Vickers, SM, 2013) |
| "Neuroblastoma is the third most common malignant solid tumor of childhood." | ( Gelfand, MJ; Parisi, MT; Sharp, SE; Shulkin, BL; Yanik, GA, 2013) |
| "Neuroblastoma is an aggressive childhood cancer, with a propensity for early widespread metastasis." | ( DuBois, SG; Matthay, KK, 2013) |
| "Neuroblastoma is one of the most common extracranial solid cancers found in young children." | ( Leung, KN; Liao, X, 2013) |
| "Neuroblastoma is responsible for 15% of all childhood cancer deaths." | ( Bray, IM; Creevey, L; Harvey, H; Khan, AR; Meehan, M; Ryan, J; Stallings, RL, 2013) |
| "Neuroblastoma is a tumor accounting for approximately 10% of all childhood malignancies and 50% of all childhood cancer-related deaths." | ( Cipro, S; Eckschlager, T; Hrabeta, J; Musil, Z; Prochazka, P; Stejskalova, E; Vicha, A; Vodicka, P, 2013) |
| "Neuroblastoma is an embryonal malignancy of the sympathetic nervous system." | ( Ackermann, S; Berthold, F; Brors, B; Deubzer, H; Ehemann, V; Fischer, M; Hero, B; Juraeva, D; Kahlert, Y; Kocak, H; Oberthuer, A; Odenthal, M; Roels, F; Theissen, J; Westermann, F, 2013) |
| "Neuroblastoma is the most common and deadly tumor of childhood, where new therapy options for patients with high-risk disease are highly warranted." | ( Baryawno, N; Fuchs, D; Johnsen, JI; Kogner, P; Martinsson, T; Milosevic, J; Mohammad, AA; Odeberg, J; Rahbar, A; Söderberg-Nauclér, C; Sveinbjörnsson, B; Taher, C; Wilhelmi, V; Wolmer-Solberg, N, 2013) |
| "Neuroblastoma is a neuroendocrine tumour derived from neural crest cells and it remains a major therapeutic challenge in pediatric oncology." | ( Arunakaran, J; Arunkumar, R; Bavithra, S; Brindha Mercy, A; Elumalai, P; Raja Singh, P; Selvakumar, K; Sugantha Priya, E, 2014) |
| "Neuroblastoma is an embryonal tumor originating from the simpatico-adrenal lineage of the neural crest." | ( Brignole, C; Caffa, I; Cilli, M; Di Paolo, D; Loi, M; Marimpietri, D; Nico, B; Pagnan, G; Pastorino, F; Perri, P; Pistoia, V; Ponzoni, M; Ribatti, D; Zuccari, G, 2013) |
| "Neuroblastoma is the most common pediatric solid tumor." | ( Blengio, F; Cangelosi, D; Conte, M; Eggert, A; Eva, A; Gambini, C; Garaventa, A; Muselli, M; Varesio, L; Versteeg, R, 2013) |
| "Neuroblastoma is the most common extracranial solid tumor of childhood and is responsible for over 15% of pediatric cancer deaths." | ( Beierle, EA; Cance, WG; Kurenova, EV; Ma, X; Megison, M; Nabers, H; Stewart, JE, 2015) |
| "Neuroblastoma is a solid tumor often diagnosed in childhood." | ( Kim, Y; Lee, HA; Park, S, 2013) |
| "Neuroblastoma is the second most common solid tumor diagnosed during infancy." | ( Kwan, Y; Lu, Y; Ngai, S; Tsai, S; Wang, C; Zhan, Q, 2013) |
| "Neuroblastoma is a pediatric cancer that continues to exact significant morbidity and mortality." | ( Attiyeh, EF; Belcastro, LT; Caponigro, G; Carpenter, EL; Cole, KA; Diskin, SJ; Hart, LS; Kim, S; Li, Y; Maris, JM; Martinez, D; Nakazawa, MS; Parasuraman, S; Pawel, B; Rader, J; Russell, MR; Schnepp, RW; Wood, AC, 2013) |
| "Neuroblastoma is characterized by florid vascularization leading to rapid tumor dissemination to distant organs; angiogenesis contributes to tumor progression and poor clinical outcomes." | ( Chung, DH; Kim, KW; Lee, S; Paul, P; Qiao, J, 2013) |
| "Neuroblastoma is the most common extracranial solid tumor in childhood." | ( Brady, NR; Lodrini, M; Oehme, I; Witt, O, 2013) |
| "Neuroblastoma is a common pediatric solid tumor that exhibits a striking clinical bipolarity: favorable and unfavorable." | ( Hicks, SL; Ikegaki, N; Jacobs, J; Jumbo, AS; Leonhardt, P; Rappaport, EF; Regan, PL; Tang, XX, 2014) |
| "Malignant neuroblastoma is an extracranial solid tumor that usually occurs in children." | ( Banik, NL; Chakrabarti, M; Mohan, N; Ray, SK, 2013) |
| "Neuroblastoma is the most common extracranial solid tumor of childhood." | ( Ganeshan, VR; Schor, NF, 2014) |
| "Neuroblastoma is an embryonal tumor accounting for approximately 15% of childhood cancer deaths." | ( Duffy, DJ; Higgins, DG; Kolch, W; Krstic, A; Schwarzl, T, 2014) |
| "Neuroblastoma is a p53 wild type malignancy at diagnosis and repression of p53 signaling plays an important role in its pathogenesis." | ( Barbieri, E; Capasso, M; Chen, Z; De Preter, K; Johansson, P; Man, TK; Shohet, JM; Speleman, F; Stowers, P; Tonini, GP, 2013) |
| "Neuroblastoma is an embryonic solid tumor of neural crest origin and accounts for 11% of all cancer-related deaths in children." | ( Berthold, F; Capper, D; Deubzer, HE; Fabian, J; Fischer, M; Hero, B; Hielscher, T; Kopp-Schneider, A; Kulozik, AE; Lodrini, M; Mahlknecht, U; Milde, T; Oehme, I; Opitz, L; Popanda, O; Roels, F; Schier, MC; Thole, TM; von Deimling, A; Westermann, F; Wiegand, I; Witt, O, 2014) |
| "Neuroblastoma is a childhood cancer with high incidence and high mortality rate." | ( Gonzalez-Nunez, V; Noriega-Prieto, JA; Rodríguez, RE, 2014) |
| "Neuroblastoma is a common neuroendocrine (NE) tumor that presents in early childhood, with a high incidence of malignancy and recurrence." | ( Carter, YM; Chen, H; Gamblin, TC; Kunnimalaiyaan, M; Kunnimalaiyaan, S, 2014) |
| "High-risk neuroblastoma is an aggressive malignancy, with high rates of treatment failure." | ( Antao, N; Cohn, SL; Cox, NJ; Diskin, SJ; Dolan, ME; Gamazon, ER; Im, HK; Konkashbaev, A; London, WB; Ludeman, SM; Maris, JM; Myers, J; Pinto, N; Stark, AL, 2014) |
| "Neuroblastoma is an embryonic tumour of the sympathetic nervous system and is one of the most common cancers in childhood." | ( Cinnella, C; D'Agnano, I; Felsani, A; Guglielmi, L; Maresca, G; Mercanti, D; Nardella, M; Valentini, A, 2014) |
| "Neuroblastoma is the most common extracranial solid tumor in childhood and is associated with serious morbidity and mortality." | ( Bao, P; Chen, K; Li, Y; Liu, Y; Sun, X; Wang, J; Wang, Y; Zhang, J; Zhou, B; Zhou, Z, 2014) |
| "Neuroblastoma is the most common extracranial pediatric solid tumor with poor prognosis in children with disseminated stage of disease." | ( Ferlazzo, N; Navarra, M; Russo, M; Schumacher, U; Ursino, MR; Valentiner, U, 2014) |
| "Neuroblastoma is the most prevalent extracranial solid tumor in childhood and has poor clinical outcome due to its high potential for metastasis." | ( Jung, CH; Kim, Y; Kim, YS; Lee, HA; Lim, JY; Yoo, SH, 2014) |
| "Neuroblastoma is a common pediatric solid tumor with poor outcome for metastatic disease." | ( Appl, B; Bergholz, R; Eschenburg, G; Luckert, C; Reinshagen, K; Roth, B, 2014) |
| "Neuroblastoma is a malignant embryonal tumor of neural crest cells that give rise to the sympathetic nervous system, responsible for 10-70% of all cases of childhood cancer." | ( Barros, JE; da Silva, HA; de Miranda, DO; Garcia, HL; Gomes, AV; Lima, CA; Lima, EL; Moraes, VL; Muniz, MT; Santos, N; Vieira, MM, 2014) |
| "Neuroblastoma is one of the most common solid tumors and accounts for ∼ 15% of all the cancer related deaths in the children." | ( Dipette, DJ; Fan, D; Kumar, A; Singh, US, 2014) |
| "Neuroblastoma is an aggressive childhood disease." | ( Cao, Z; Gu, Z; Li, G; Liu, G; Wang, X; Yang, Z; Zhang, S, 2014) |
| "Neuroblastoma is an embryonic childhood cancer with high mortality." | ( Graham, G; Khan, J; Li, X; Selich-Anderson, J; Shah, N; Siddiqui, H; Toretsky, J; Wang, J, 2014) |
| "Neuroblastoma is a common pediatric solid tumor with the potential to be targeted using immunotherapy." | ( Barrett, DM; Grupp, SA; Hulitt, J; Jiang, S; June, CH; Liu, X; Singh, N; Zhao, Y, 2014) |
| "Neuroblastoma is unique amongst common pediatric cancers for its expression of the norepinephrine transporter (NET), enabling tumor-selective imaging and therapy with radioactive analogues of norepinephrine." | ( Cripe, TP; Kunkler, A; Ranalli, MA; Shah, N; Streby, KA, 2015) |
| "Neuroblastoma is an aggressive pediatric malignancy with significant chemotherapeutic resistance." | ( Correard, F; Esteve, MA; Khoumeri, O; Montana, M; Terme, T; Vanelle, P, 2014) |
| "Neuroblastoma is the most common malignancy in infancy, it is a histologically and genetically heterogeneous tumor, the therapy and outcome of which is influenced by age, histological variant and genetic background as well." | ( Bartyik, K; Csanády, M; Majoros, V; Rovó, L; Vass, G, 2014) |
| "Neuroblastoma is a common solid malignant tumor of the sympathetic nervous system, which contributes to 15% of cancer‑related mortality in children." | ( Cui, H; Hu, R; Ke, XX; Peng, H; Wei, Y; Yang, L, 2015) |
| "Neuroblastoma is an aggressive extracranial pediatric solid tumor, with significant chemotherapeutic resistance." | ( Cui, H; Hu, R; Huang, M; Ke, XX; Yan, X; Zhao, H, 2015) |
| "Neuroblastoma is the most common extracranial solid tumor in children." | ( Aktas, S; Altun, Z; Cecen, E; Ercetin, P; Olgun, N, 2014) |
| "Neuroblastoma is the most common pediatric extracranial solid tumor with a broad spectrum of clinical behavior and poor prognosis." | ( Bai, X; Ji, J; Li, Z; Liu, C; Ren, X; Ren, Y; Tang, L; Wang, Q; Wei, S; Zhang, X; Zhao, X, 2015) |
| "Neuroblastoma is a rare malignant disease and mainly affects infants and very young children." | ( Berthold, F; Peinemann, F; Tushabe, DA; van Dalen, EC, 2015) |
| "Neuroblastoma is the most common cancer of infancy and accounts for 15% of all pediatric oncology deaths." | ( Haber, M; Huynh, T; Norris, MD; Truong, AM; Yu, DM, 2015) |
| "Neuroblastoma is an exclusively TP53 wild type tumor at diagnosis and inhibition of p53 is required for tumorigenesis." | ( Dayaram, T; Donehower, LA; Ganji, G; Gilmartin, AG; Kumar, R; Pemmasani, SK; Richter, M; Shohet, JM; Van Der Key, H, 2015) |
| "Neuroblastoma is the most common extracranial solid tumor in children, causing 12% of all pediatric cancer mortality." | ( Boes, M; Meyer-Wentrup, F, 2015) |
| "Neuroblastoma is the predominant tumor of early childhood." | ( Chen, GH; Chen, Z; Liu, YF; Luo, Q; Tian, PC; Wang, HL; Wang, Y, 2016) |
| "Patients with neuroblastoma are now stratified at diagnosis according to the presence and number of image-defined risk factors (IDRFs)." | ( Brisse, HJ; Canale, S; Elie, C; Galmiche-Rolland, L; Irtan, S; Le Cossec, C; Michon, J; Minard-Colin, V; Sarnacki, S; Schleiermacher, G; Valteau-Couanet, D, 2015) |
| "Neuroblastoma is a predominantly p53 wild-type (wt) tumour and MDM2-p53 antagonists offer a novel therapeutic strategy for neuroblastoma patients." | ( Chen, L; Lunec, J; Middleton, SA; Newell, DR; Nichols, GL; Rousseau, RF; Tweddle, DA, 2015) |
| "Neuroblastoma is one of the most aggressive cancers and has a complex form of differentiation." | ( Chen, HY; Hong, YR; Lee, CI; Perng, JH; Wang, JJ, 2015) |
| "Neuroblastoma is the most common cancer in infants and the fourth most common cancer in children." | ( Chen, X; Li, C; Li, S; Li, Y; Lv, H; Tang, K; Yu, S; Zhou, W, 2015) |
| "Neuroblastoma is among the most fatal of solid tumors in the pediatric age group, even when treated aggressively." | ( Kurita, M; Nishimura, Y; Suzuki, T; Tabata, K; Takeda, T; Uchiyama, T, 2015) |
| "Neuroblastoma is a challenging childhood malignancy, with a very high percentage of patients relapsing following acquisition of drug resistance, thereby necessitating the identification of mechanisms of drug resistance as well as new biological targets contributing to the aggressive pathogenicity of the disease." | ( Alcock, L; Bray, I; Buckley, P; Conlon, R; Dowling, P; Harvey, H; Henry, M; Nolan, J; O'Sullivan, F; Piskareva, O; Stallings, RL, 2015) |
| "High-risk neuroblastoma is associated with an overall survival rate of 30-50%." | ( Bartakova, A; Delaney, J; McCabe, KE; Newbury, RO; Pizzo, DP; Schlaepfer, DD; Stupack, DG; Varner, JA; Young, SA, 2015) |
| "Neuroblastoma is a rare malignant disease and mainly affects infants and very young children." | ( Berthold, F; Peinemann, F; Tushabe, DA; van Dalen, EC, 2015) |
| "Neuroblastoma is a childhood cancer with poor long-term prognosis in advanced stages." | ( Brignole, C; Cilli, M; Di Paolo, D; Emionite, L; Loi, M; Marchetti, C; Milelli, A; Minarini, A; Pagnan, G; Parise, A; Pastorino, F; Perri, P; Petretto, A; Piaggio, F; Pistoia, V; Ponzoni, M; Tumiatti, V; Zuccari, G, 2015) |
| "Neuroblastoma is the most common extracranial solid tumor of childhood, and survival remains poor for patients with advanced disease." | ( Anderson, J; Bendle, G; Chesler, L; De Santo, C; Egan, S; Fisher, J; Hunter, S; McConville, C; Mussai, F; Petrie, K; Sbirkov, Y; Webber, H; Wheat, R; Wheeler, K, 2015) |
| "Neuroblastoma is a childhood malignancy that has not yet benefitted from the rapid progress in the development of small-molecule therapeutics for cancer." | ( Chesler, L; Danielson, LS; Innocenti, P; Tucker, ER, 2015) |
| "Neuroblastoma is the most common cancer in infants and the fourth most common cancer in children." | ( Adam, V; Cerna, T; Doktorova, H; Eckschlager, T; Frei, E; Groh, T; Hrabeta, J; Khalil, MA; Kizek, R; Poljakova, J; Stiborova, M; Uhlik, J, 2015) |
| "Neuroblastoma is one of the most common solid tumors in childhood and usually accompanied with poor prognosis and rapid tumor progression when diagnosed with amplification of the proto-oncogene N-Myc." | ( Bruchelt, G; Cabanillas Stanchi, KM; Handgretinger, R; Holzer, U, 2015) |
| "Neuroblastoma is the most common extra-cranial solid tumor of childhood and it is characterized by the presence of a glycosphingolipid, GD2 ganglioside." | ( Augustyniak, E; Boratyn, E; Drożniak, J; Durbas, M; Górka, A; Horwacik, I; Kowalczyk, A; Krzanik, S; Rokita, H; Sawicka, A; Węgrzyn, P, 2015) |
| "Neuroblastoma is the most common extra-cranial solid tumor in pediatric patients." | ( Arnone, G; Caobelli, F; Cistaro, A; Coppolino, P; Ficola, U; Paratore, R; Piccardo, A; Quartuccio, N; Sperandeo, A, 2015) |
| "Neuroblastoma is characterized by a wide range of clinical manifestations and associated with poor prognosis when there is amplification of MYCN oncogene or high expression of Myc oncoproteins." | ( Chen, TY; Chuang, JH; Hsu, WM; Huang, CC; Lin, LL; Lin, TK; Liou, CW; Wang, PW; Wang, SY, 2015) |
| "Neuroblastoma is an embryonic tumour of childhood that originates in the neural crest." | ( Adam, JA; Bleeker, G; Caron, HN; Hooft, L; Kremer, LC; Tytgat, GA; van Dalen, EC, 2015) |
| "Neuroblastoma is an embryonic tumour of childhood that originates in the neural crest." | ( Adam, JA; Bleeker, G; Caron, HN; Hooft, L; Kremer, LC; Tytgat, GA; van Dalen, EC, 2015) |
| "In children, neuroblastomas are the most common and deadly solid tumor." | ( Chang, YA; Chen, RM; Lin, CJ; Wang, JJ; Wang, W; Yeh, PS, 2016) |
| "Neuroblastoma is the most common extracranial solid childhood tumor, which is believed to originate from primitive neuroblasts giving rise to the sympathetic nervous system." | ( Fagone, P; Magro, G; Nicoletti, F; Parenti, R; Vecchio, GM, 2015) |
| "High-risk neuroblastoma is characterised by poor long-term survival, especially for very high-risk (VHR) patients (poor response of metastases after induction therapy)." | ( Dufour, C; Goma, G; Lapierre, V; Pasqualini, C; Raquin, MA; Valteau-Couanet, D, 2016) |
| "Neuroblastoma is the most common and one of the deadliest among pediatric tumors; however, a subset of infants with neuroblastoma display spontaneous regression." | ( Chen, CF; Chen, X; Dong, Q; Gao, Q; Hou, L; Li, X; Lu, HT; Zhang, HY; Zhi, YL, 2015) |
| "Neuroblastoma is a paediatric malignancy that typically arises in early childhood, and is derived from the developing sympathetic nervous system." | ( Abraham, BJ; Anders, L; Bramlett, K; Capasso, M; Crimmins, I; Diamond, M; Diskin, SJ; Durbin, AD; Gerhard, DS; Guidry Auvil, JM; Hakonarson, H; Hart, LS; Iolascon, A; Khan, J; Look, AT; Maris, JM; McDaniel, LD; Oldridge, DA; Rahman, N; Sussman, R; Tian, L; Wei, JS; Weichert-Leahey, N; Winter, C; Wood, AC; Young, RA; Zhang, S; Zhu, S, 2015) |
| "Neuroblastoma is an embryonal pediatric tumor that originates from the developing sympathetic nervous system and shows a broad range of clinical behavior, ranging from fatal progression to differentiation into benign ganglioneuroma." | ( Ackermann, S; Berthold, F; Dreidax, D; Engesser, A; Fischer, M; Henrich, KO; Hero, B; Hertwig, F; Ikram, F; Kahlert, Y; Kocak, H; Nürnberg, P; Roels, F; Volland, R; Westermann, F, 2016) |
| "Neuroblastoma is the most common extra-cranial solid tumor in childhood; and patients in stage IV of the disease have a high propensity for tumor recurrence." | ( Kiningham, KK; McCormick, ML; Silvis, AM; Spitz, DR, 2016) |
| "Neuroblastoma is a malignant embryonal tumor occurring in young children, consisting of undifferentiated neuroectodermal cells derived from the neural crest." | ( Almacellas, E; Ambrosio, S; Cortes, CL; Ferreres, JC; Hernández-Losa, J; Kozma, SC; Tauler, A; Thomas, G; Veiga, SR, 2016) |
| "Neuroblastoma is among the most common extracranial solid tumors in pediatric patients and typically arises anywhere from the neck to pelvis but most commonly in the adrenal glands." | ( Servaes, S; Zhang, W; Zhuang, H, 2016) |
| "Neuroblastoma is a childhood neural crest tumor." | ( Li, X; Schor, NF; Wang, S; Yang, YP, 2016) |
| "Neuroblastoma is the most common malignant tumor observed during the neonatal period." | ( De Souza, VF; Dietrich, C; Faria, AE; Masiero, Á; Michelon, L; Pires, SR; Provenzi, VO; Rosa, RF; Targa, LV; Zen, PR, 2016) |
| "Neuroblastoma is the most common extra-cranial malignancy in childhood and accounts for ∼15% of childhood cancer deaths." | ( Ardley, K; Cullinane, C; Hicks, RJ; Johnstone, RW; Li, J; Martin, B; McArthur, GA; Shortt, J; Tothill, RW; Waldeck, K; Wood, PJ, 2016) |
| "Neuroblastoma is a rare malignant disease and patients with high-risk neuroblastoma have a poor prognosis." | ( Berthold, F; Peinemann, F; van Dalen, EC, 2016) |
| "Neuroblastoma is one of the most common types of pediatric tumors that can spread quickly in neuronal tissues." | ( Bağcı, G; Dodurga, Y; Eroğlu, C; Seçme, M, 2016) |
| "Neuroblastoma is the most commonly extra-cranial solid tumor of childhood frequently diagnosed." | ( Agriesti, F; Capitanio, N; Fratello, A; Laurenzana, I; Mazzoccoli, C; Piccoli, C; Ruggieri, V; Tataranni, T, 2016) |
| "Neuroblastoma is a rare malignant disease and patients with high-risk neuroblastoma have a poor prognosis." | ( Berthold, F; Peinemann, F; van Dalen, EC, 2016) |
| "Neuroblastoma is one of the most common childhood malignancies and the primary cause of death from pediatric cancer." | ( Gorska, M; Kuban-Jankowska, A; Milczarek, R; Wozniak, M, 2016) |
| "Metastatic neuroblastoma is an aggressive malignancy with a poor prognosis." | ( Fujisaki, H; Hara, J; Nakano, Y; Nitani, C; Okada, K; Yamasaki, K, 2016) |
| "Neuroblastoma is frequently diagnosed at advanced stage disease and treatment includes high dose chemotherapy and surgery." | ( Boyer, C; Brandl, M; Cirillo, G; Duong, H; Fleming, C; Gaus, K; Haber, M; Hinde, E; Kavallaris, M; Kimpton, K; Kumar, N; Norris, M; Vittorio, O; Yee, E, 2016) |
| "Neuroblastoma is the most common tumor amongst children amounting to nearly 15% of cancer deaths." | ( Cherian, KM; Karthik, S; Mathuram, TL; Ravikumar, V; Reece, LM; Sasikumar, CS, 2016) |
| "Neuroblastoma is a childhood cancer of the sympathetic nervous system with embryonic origins." | ( Basta, PV; Carrier, KS; Diskin, SJ; Engel, SM; Maris, JM; Maxen, C; Mazul, AL; Naranjo, A; Olshan, AF; Siega-Riz, AM; Vaksman, Z; Weinberg, CR; Zou, F, 2016) |
| "Neuroblastoma is a pediatric malignancy, and most tumor cells express the norepinephrine transporter (NET) enabling uptake of NET ligands." | ( Batra, V; Elias, J; Makvandi, M; Maris, JM; Patel, N; Pryma, DA; Zuppa, AF, 2017) |
| "Neuroblastoma is the most common extracranial solid tumor during infancy and childhood." | ( Appl, B; Eschenburg, G; Hundsdoerfer, P; Langemann, D; Najem, S; Reinshagen, K; Trochimiuk, M, 2016) |
| "Neuroblastoma is the most common extra-cranial malignancy of childhood, with the highest incidence in children younger than 4 years." | ( Brodkiewicz, A; Peregud-Pogorzelski, J; Szychot, E; Wawryków, P, 2016) |
| "Neuroblastoma is the most common solid tumor in early childhood." | ( Atmadibrata, B; Liu, PY; Liu, T; Mondal, S; Tee, AE, 2016) |
| "Neuroblastoma is the most frequent, extracranial solid tumor in children with still poor prognosis in stage IV disease." | ( Ausserlechner, MJ; Geiger, K; Hagenbuchner, J; Kiechl-Kohlendorfer, U; Meister, B; Müller, T; Obexer, P; Rupp, M; Salvador, C; Sergi, C, 2016) |
| "Neuroblastoma is the most common extracranial childhood solid tumor." | ( Chiu, B; Coburn, J; Harris, J; Ikegaki, N; Kajdacsy-Balla, A; Kaplan, DL; Lyubimov, AV; Pilichowska, M; Poirier, J; Shimada, H; Zakharov, AD, 2017) |
| "Neuroblastoma is the most common human extracranial solid tumor during infancy." | ( Banelli, B; Barbagallo, C; Barbagallo, D; Di Mauro, S; Di Pietro, C; Magro, G; Maugeri, M; Purrello, F; Purrello, M; Ragusa, M; Romani, M, 2016) |
| "Neuroblastoma is the most common extracranial solid tumour occurring in childhood and has a diverse clinical presentation and course depending on the tumour biology." | ( Diller, L; Mackall, CL; Maris, JM; Matthay, KK; Nakagawara, A; Schleiermacher, G; Weiss, WA, 2016) |
| "Neuroblastoma is the most common extracranial tumor in children." | ( Althoff, K; Astrahanseff, K; Beckers, A; Bergmann, A; De Preter, K; Eggert, A; Henssen, AG; Odersky, A; Schäfers, S; Schramm, A; Schulte, JH; Seiler, M; Speleman, F; Struck, J; Szymansky, A, 2017) |
| "Neuroblastoma is the most common extracranial solid tumor in children." | ( Chen, Z; Guan, S; Lu, J; Mao, X; Pang, JC; Tao, L; Vasudevan, SA; Woodfield, SE; Yang, J; Yu, Y; Zhang, F; Zhang, H; Zhao, Y, 2017) |
| "Neuroblastoma is the most common solid neoplasia in children." | ( Fico, F; Lococo, E; Mardente, S; Mari, E; Morgante, E; Tafani, M; Valentini, F; Zicari, A, 2016) |
| "Neuroblastoma is the most common solid extracranial malignancy diagnosed in childhood." | ( Davidson, DF; Dow, E; Kelly, AU; Srivastava, R, 2017) |
| "Neuroblastoma is a common childhood cancer typically treated by inducing differentiation with retinoic acid (RA)." | ( Chen, L; Dobrzański, TP; Gonzalez, FJ; Kang, BH; Müller, R; Peters, JM; Yao, PL; Zhu, B, 2017) |
| "Neuroblastomas are the most common solid extracranial tumors in childhood." | ( An, RB; Bastola, T; Kim, J; Kim, YC; Seo, J, 2017) |
| "Neuroblastoma is an embryonic malignancy of early childhood originating from neural crest cells and showing heterogeneous biological, morphological, genetic and clinical characteristics." | ( Aveic, S; Esposito, MR; Seydel, A; Tonini, GP, 2017) |
| "Neuroblastoma is predominantly characterised by chromosomal rearrangements." | ( Bate-Eya, LT; Caron, HN; Dolman, MEM; Ebus, ME; Gierman, HJ; Koster, J; Molenaar, JJ; Versteeg, R, 2017) |
| "Neuroblastoma is an embryonic tumor of the peripheral sympathetic nervous system, and is metastatic or otherwise high risk for relapse in nearly 50% of cases, with a long-term survival of <40%." | ( Pfluger, T; Piccardo, A, 2017) |
| "Neuroblastoma is one of the most common cancers in infancy, arising from the neuroblasts during embryonic development." | ( Jaroonwitchawan, T; Noisa, P; Suebsoonthron, J; Yamabhai, M, 2017) |
| "Neuroblastoma is the most common extracranial solid tumour of infancy." | ( Beneš, P; Budková, Z; Jiráková, L; Karasová, M; Kohutková Lánová, M; Navrátilová, J; Pacherník, J; Šmarda, J, 2017) |
| "Neuroblastoma is a childhood malignancy originating from the sympathetic nervous system and accounts for approximately 15% of all pediatric cancer-related deaths." | ( Fujiwara, K; Fukuda, N; Hirano, T; Hoshi, R; Ishizuka, Y; Kawashima, H; Koshinaga, T; Nagasaki-Maeoka, E; Nagase, H; Ohashi, K; Ozaki, T; Soma, M; Sugito, K; Uekusa, S; Watanabe, Y; Yoshizawa, S, 2017) |
| "Neuroblastoma is a refractory pediatric malignant solid tumor." | ( Hara, F; Naoe, A; Suzuki, T; Uga, N; Watanabe, S; Yasui, T, 2017) |
| "Neuroblastoma is an embryonal tumor arising from neuroblast cells of the autonomic nervous system, which is the most common cancer diagnosed in infants." | ( Chi, Z; Hao, L; Li, S; Sun, R; Wang, H, 2017) |
| "Neuroblastoma is the second most common extracranial malignant solid tumor that occurs in childhood, and metastasis is one of the major causes of death in neuroblastoma patients." | ( Gao, ZM; Huang, WY; Lu, ZB; Shao, JB, 2017) |
| "Neuroblastoma is a pediatric solid tumor with high expression of the tumor associated antigen disialoganglioside GD2." | ( Carcaboso, AM; Castillo-Ecija, H; Cheung, NKV; Cuadrado-Vilanova, M; de Torres, C; Ferrandiz, MM; Glisoni, R; Jungbluth, A; Kuplennik, N; Lavarino, C; Monterrubio, C; Mora, J; Olaciregui, NG; Paco, S; Pascual-Pasto, G; Sosnik, A; Vila-Ubach, M, 2017) |
| "Neuroblastoma is the most frequent extra-cranial solid tumor in children with still high mortality in stage M." | ( Ausserlechner, MJ; Ferlin, MG; Hagenbuchner, J; Kiechl-Kohlendorfer, U; Lungkofler, L; Obexer, P; Viola, G, 2017) |
| "Neuroblastoma is the most common extracranial solid tumor in children and accounts for 8% to 10% of all childhood cancers." | ( Castellano, A; D'Andrea, ML; Garganese, MC; Pizzoferro, M; Villani, MF, 2017) |
| "Neuroblastoma is the most common solid tumor in childhood and develops from undifferentiated progenitor cells of the sympathetic nervous system." | ( Ausserlechner, MJ; Hermann, M; Kiechl-Kohlendorfer, U; Obexer, P; Salcher, S, 2017) |
| "Neuroblastoma is the most common cancer in infancy and extremely heterogeneous in clinical presentation and features." | ( Brunak, S; Halasz, M; Huber, KVM; Kolch, W; Papamarkou, T; Radic-Sarikas, B; Superti-Furga, G; Tsafou, KP; Winter, GE, 2017) |
| "Neuroblastoma is a biologically and clinically heterogeneous pediatric malignancy that includes a high-risk subset for which new therapeutic agents are urgently required." | ( Cinatl, J; Gallacher, K; Kaidi, A; Kollareddy, M; Malik, K; Melegh, Z; Michaelis, M; Oltean, S; Park, JH; Sherrard, A; Szemes, M, 2017) |
| "Neuroblastoma is a pediatric cancer characterized by variable outcomes ranging from spontaneous regression to life-threatening progression." | ( Fell, SM; Holmberg, J; Kogner, P; Li, S; Nyman, U; Schlisio, S; Shi, Y; Södersten, E; Surova, O; Toskas, K; Westerlund, I, 2017) |
| "Neuroblastoma is a malignancy [corrected] of childhood and accounts for 7-10% of childhood cancers, leading to approximately 15% of pediatric cancer deaths." | ( Cao, X; Dai, S; Fu, MC; Lv, Y; Wang, J; Xia, HL; Xiong, QW; Xu, CW; Yan, XM; Zhang, T; Zhou, Y, 2017) |
| "Neuroblastoma is a cancer of the neural crest almost exclusively seen in childhood." | ( Dedhe, A; Hansen, JN; Li, X; Lotta, LT; Schor, NF; Zheng, YG, 2017) |
| "Neuroblastoma is a rare malignant disease and mainly affects infants and very young children." | ( Berthold, F; Enk, H; Peinemann, F; van Dalen, EC, 2017) |
| "Neuroblastoma is the most common form of childhood extracranial tumor and almost half of neuroblastoma cases occur in infants under two years old." | ( Liu, Q; Qin, P; Shi, L; Wang, Q; Zhang, J, 2017) |
| "Neuroblastoma is the most common extracranial solid childhood tumor." | ( Chen, X; Ding, X; Du, W; Fang, F; Hu, S; Li, M; Li, X; Li, Z; Lu, J; Pan, J; Qian, G; Ren, J; Tao, Y; Wang, J; Wu, Y; Xu, L; Xu, Y; Yang, C; Zhao, H, 2017) |
| "Neuroblastoma is a vascularized pediatric tumor derived from neural crest stem cells that displays vasculogenic mimicry and can express a number of stemness markers, such as SOX2 and NANOG." | ( Cheung, NK; Kim, J; Nakayama, M; Okano, T; Parsa, H; Sakaguchi, K; Shimizu, T; Villasante, A; Vunjak-Novakovic, G, 2017) |
| "Neuroblastoma is the most common extracranial solid tumour in children, and differentiation is considered its most appropriate therapy." | ( Ghahremani, MH; Sharif, S; Soleimani, M, 2017) |
| "Childhood neuroblastoma is a heterogenous disease with varied clinical presentation and biology requiring different approaches to investigation and management." | ( Ahmadzadehfar, H; Alexander, N; Baruchel, S; Shammas, A; Vali, R, 2018) |
| "Neuroblastoma is one of the most commonly encountered malignant solid tumors in the pediatric age group." | ( Asami, S; Kurita, M; Ono, S; Suzuki, T; Takada, T; Uchiyama, T; Wakabayashi, N, 2018) |
| "Neuroblastoma is one of only a few human cancers that can spontaneously regress even after extensive dissemination, a poorly understood phenomenon that occurs in as many as 10% of patients." | ( Czaplinski, S; Geerts, D; Groß, A; Harter, PN; Khilan, A; Klingebiel, T; Kolb, J; Koster, J; Langer, JD; Rohrer, H; Schulte, D; Schulz, C; Wehner, S, 2018) |
| "Neuroblastoma is the primary cause of cancer-related death for children 1 to 5 years of age." | ( Jiang, J; Lei, K; Ni, Y; Song, X; Sun, L; Yang, J; Zhou, F, 2018) |
| "Outcomes of IR neuroblastoma are favorable." | ( Amin, N; Bhagat, M; Chinnaswamy, G; Harris, C; Kembhavi, S; Khanna, N; Laskar, S; Prasad, M; Qureshi, SS; Ramadwar, M; Shetty, O; Talole, S; Vora, T, 2018) |
| "Advanced stage neuroblastoma is an aggressive disease with limited treatment options for patients with drug-resistant tumors." | ( Brahmbhatt, H; Fife, CM; Gifford, AJ; Kavallaris, M; MacDiarmid, JA; MacMillan, A; McCarroll, JA; Sagnella, SM; Trieu, J; Whan, RM; Ziegler, DS, 2018) |
| "Adult-onset neuroblastoma is rare and little is known about its biology and clinical course." | ( Basu, EM; Cheung, NV; Hammond, WJ; Kramer, K; Kushner, BH; LaQuaglia, MP; Modak, S; Roberts, SS; Suzuki, M; Wolden, SL, 2018) |
| "Neuroblastoma is a rare solid tumour of infancy and early childhood with a disproportionate contribution to paediatric cancer mortality and morbidity." | ( Fletcher, JI; Haber, M; Marshall, GM; Norris, MD; Trahair, TN; Ziegler, DS, 2018) |
| "High-risk neuroblastoma is characterized by poor long-term survival, especially for very high-risk (VHR) patients (poor response of metastases after induction therapy)." | ( Bogart, E; Chastagner, P; Cougnenc, O; Defachelles, AS; Ferry, I; Kolesnikov-Gauthier, H; Michon, J; Oudoux, A; Proust, S; Schleiermacher, G; Valteau-Couanet, D, 2018) |
| "Treatment of neuroblastoma is based on the combination of chemotherapy with other therapeutic interventions such as surgery, radiotherapy, use of differentiating agents, and immunotherapy." | ( Brandetti, E; Cifaldi, L; Ognibene, M; Pezzolo, A; Pistoia, V; Veneziani, I, 2018) |
| "Advanced stage neuroblastoma is a very aggressive pediatric cancer with limited treatment options and a high mortality rate." | ( Berbegall, AP; Bondarenko, GI; Dubrovskyi, O; Giles, FJ; Hendrix, MJ; Mazar, AP; Navarro, S; Noguera, R; O'Halloran, TV; Ugolkov, AV, 2018) |
| "High-risk neuroblastoma is a devastating malignancy with very limited therapeutic options." | ( Abhari, BA; Angeli, JPF; Bayır, H; Chirumamilla, CS; Choi, SM; Conrad, M; De Geest, BG; Declerck, K; Ekert, PG; Fulda, S; Hassannia, B; Heyninck, K; Ingold, I; Kagan, VE; Krysko, DV; Lahtela-Kakkonen, M; Meul, E; Qu, F; Tyurina, YY; Van Camp, G; Van Herck, S; Vanden Berghe, T; Vanden Berghe, W; Vandenabeele, P; Wiernicki, B, 2018) |
| "Neuroblastoma is the most common extracranial solid neuroendocrine cancer and is one of the leading causes of death in children." | ( Jiang, HM; Wu, JC; Yang, XH; Zheng, HC, 2018) |
| "Neuroblastoma is the most common malignancy of childhood: high-risk patients, having N-MYC over-expression, undergo aggressive therapy and show high mortality or an increased risk of secondary malignancies." | ( Farabegoli, F; Govoni, M; Papi, A; Spisni, E, 2018) |
| "Neuroblastoma is the most common cancer of the sympathetic nervous system in children." | ( Jaroonwitchawan, T; Namkaew, J; Noisa, P; Rujanapun, N; Saelee, J, 2018) |
| "Neuroblastoma is the most common extracranial solid malignancy in the pediatric population, accounting for over 9% of all cancer-related deaths in children." | ( Bhat, N; Chen, L; Dower, CM; Gebru, MT; Miller, BA; Wang, HG; Wills, CA, 2018) |
| "Precise excision of neuroblastoma is challenging, especially when tumors adhere to vital structures." | ( Chen, LL; Chiu, B; Ikegaki, N; Taylor, JS; Zeki, J, 2018) |
| "Neuroblastoma is a malignant childhood cancer arising from the embryonic sympathoadrenal lineage of the neural crest." | ( Andres, C; Boehm, R; Bruckmueller, H; Cascorbi, I; Frehse, S; Haeusgen, W; Herdegen, T; Reinecke, K; Waetzig, V, 2019) |
| "Neuroblastoma is a childhood tumor arising from developing a sympathetic nervous system and causes around 10% of pediatric tumors." | ( Gill, BS; Kumar, S, 2019) |
| "Neuroblastoma is a rare pediatric cancer characterized by a wide clinical behavior and adverse outcome despite aggressive therapies." | ( Brignole, C; Corti, A; Curnis, F; Di Paolo, D; Pastorino, F; Perri, P; Ponzoni, M, 2019) |
| "Neuroblastoma is an embryonic malignancy that arises out of the neural crest cells of the sympathetic nervous system." | ( Abdullah, A; d'Hellencourt, CL; Ravanan, P; Talwar, P, 2019) |
| "Childhood neuroblastoma is a hypervascular tumor of neural origin, for which antiangiogenic drugs are currently being evaluated; however, predictive biomarkers of treatment response, crucial for successful delivery of precision therapeutics, are lacking." | ( Anderson, J; Barone, G; Blackledge, MD; Carceller, F; Chesler, L; Clarke, M; Jamin, Y; Jerome, NP; Koers, A; Koh, DM; Marshall, LV; McErlean, CM; McHugh, K; Moreno, L; Pearson, ADJ; Poon, E; Robinson, SP; Sebire, N; Vaidya, SJ; Yuan, Y; Zormpas-Petridis, K, 2019) |
| "Neuroblastoma is the most common extracranial childhood tumor, and current treatment requires surgical resection and multidrug chemotherapy." | ( Chiu, B; Coburn, JM; Harrington, K; Ikegaki, N; Kaplan, DL; Taylor, J; Yavuz, B; Zeki, J, 2019) |
| "Adult neuroblastoma is an extremely infrequent neoplasm, usually occurring in the adrenal medulla or in the paraspinal sympathetic ganglia, as its childhood counterpart." | ( Berbegall, AP; Blanquer-Maceíras, MT; Ferrández, A; Machado, I; Martinez-Ciarpaglini, C; Navarro, S; Nieto, G; Noguera, R; Yoshida, A, 2019) |
| "Neuroblastoma is a solid malignant tumor of the sympathetic nervous system, which accounts for 8-10% of childhood cancers." | ( Cha, JY; Jeong, YJ; Kang, I; Kwak, HJ; Lee, SI; Yeo, EJ; Yu, AR, 2019) |
| "Neuroblastoma is the most common extracranial malignant solid tumor in children, and drug resistance is a major reason for poor outcomes." | ( Chen, Z; Fan, Y; Guo, K; Li, H; Lu, J; Nuchtern, JG; Vasudevan, SA; Woodfield, SE; Yang, J; Yu, Y; Zhao, Y, 2019) |
| "High-risk neuroblastoma is associated with low survival rates and increased risks of treatment-related side-effects." | ( Boumil, E; Shea, TB; Theochares, B; Vohnoutka, R, 2019) |
| "Neuroblastoma is the most common extracranial solid tumor in childhood." | ( Gawdi, A; Mubarak, M; Singal, AK, 2019) |
| "Neuroblastoma is the fourth most common type of extracranial malignant solid tumor in children." | ( Cao, Y; Hou, L; Ju, C; Sun, W; Wang, X; Zhang, L, 2019) |
| "Neuroblastoma is the main solid extracranial tumor of childhood." | ( Esparza, RM; Gutiérrez, AG; Hernández-Lemus, E; Mejía, C; Ruiz-Azuara, L; Vázquez-Aguirre, A, 2019) |
| "Although neuroblastoma is a heterogeneous cancer, a substantial portion overexpresses CD71 (transferrin receptor 1) and MYCN." | ( Bishayee, K; Habib, K; Huh, SO; Sadra, A, 2019) |
| "A unique feature of neuroblastoma is remission in some patients due to spontaneous differentiation of metastatic tumors." | ( Connell, AJ; Glazewski, L; Halakos, EG; Mason, RW; Wei, S, 2019) |
| "Recurrent high-risk neuroblastoma is a childhood cancer that often fails to respond to therapy." | ( Chen, WH; Kang, MH; Koneru, B; Makena, MR; Nguyen, TH; Reynolds, CP; Urias, E; Wei, SJ, 2019) |
| "Neuroblastoma is an aggressive form of cancer with high mortality." | ( de Moura Escobar, SJ; de Oliveira Ribeiro, CA; Martin, N; Martinez, GR; Rocha, MEM; Simone, M; Winnischofer, SMB; Witting, PK, 2019) |
| "Neuroblastoma is a neural crest-derived embryonal tumor and accounts for about 15% of all cancer deaths in children." | ( Chen, CN; Chen, SF; Cheung, CHY; Hou, CL; Hsieh, CH; Hsu, CL; Hsu, WM; Huang, CT; Huang, HC; Juan, HF; Liu, YL; Yang, TS, 2019) |
| "High-risk neuroblastoma is associated with low long-term survival rates due to recurrence or metastasis." | ( Chuang, HC; Chuang, JH; Hsu, WM; Huang, CC; Liao, PL; Lin, HY; Lin, LL, 2020) |
| "Neuroblastoma is the most common extracranial solid tumor in children and originates from poorly differentiated neural crest progenitors." | ( Derks, YHW; Grytsenko, PG; Middelbeek, JAJ; van Emst, L; van Ingen Schenau, DS; van Leeuwen, FN; Vervoort, BMT; Vrenken, KS, 2020) |
| "Neuroblastoma is a deadly pediatric solid tumor with infrequent recurrent somatic mutations." | ( Bruzoni, M; Chiu, B; Coles, GL; Danzer, E; Dunn, JCY; Hazard, FK; Huang, M; Lacayo, NJ; Sakamoto, KM; Spunt, SL; Sumarsono, N; Taylor, JS; Zeki, J, 2020) |
| "Neuroblastoma is a heterogenous disease, with solid tumors arising in the adrenal gland or paraspinal regions in young children." | ( Grant, CN; Olecki, E, 2019) |
| "Neuroblastoma is the most common pediatric extracranial solid malignancy with limited effective treatment." | ( Chiu, B; Coburn, J; Harrington, K; Ikegaki, N; Kaplan, DL; Shimada, H; Taylor, JS; Wood, L; Yavuz, B; Zeki, J, 2020) |
| "Neuroblastoma is a malignant solid tumor that originates from the sympathetic nervous system in early childhood." | ( Övey, İS; Özkal, B, 2020) |
| "Neuroblastoma is a sympathetic nervous system tumor, primarily presenting in children under 6 years of age." | ( Bergendahl, G; Berry, D; Broglio, K; Brown, VI; Eslin, D; Ferguson, W; Foley, J; Kraveka, JM; Lewis, EC; Lorenzi, E; Mitchell, D; Oesterheld, J; Rawwas, J; Rich, M; Roberts, W; Saulnier Sholler, GL; Wada, RK; Zage, P, 2020) |
| "Neuroblastoma is a common solid tumor of young children that arises from anomalies in neural crest development." | ( Anderson, J; Barone, G; Blackledge, MD; Boult, JKR; Carceller, F; Chesler, L; Clarke, M; Jamin, Y; Jerome, NP; Koers, A; Koh, DM; McHugh, K; Moreno, L; Pearson, ADJ; Poon, E; Robinson, SP; Sebire, N; Yuan, Y; Zormpas-Petridis, K, 2020) |
| "Neuroblastoma is the most common inheritable, solid neoplasm in children found under the age of 7 and accounts for approximately 7% of childhood cancers." | ( Fultang, N; Illendula, A; Peethambaran, B, 2020) |
| "To date, high-risk neuroblastoma is associated with low survival rates." | ( Bamodu, OA; Chao, TY; Haryana, SM; Hsiao, M; Hsu, WM; Liu, YL; Pikatan, NW; Yeh, CT, 2020) |
| "Neuroblastoma is a heterogenous tumor whose characteristics range from spontaneous regression to aggressive phenotypes that are due to different mutations that often occur in SRC family kinases." | ( Aventaggiato, M; Francioso, A; Kuznetsova, L; Malyshev, I; Mardente, S; Mari, E; Mosca, L; Tafani, M; Valentini, F; Zicari, A, 2020) |
| "Neuroblastoma is a childhood solid tumour originating from undifferentiated neural progenitor cells of the sympathetic nervous system." | ( Abassi, Y; Bexell, D; Bonne Køhler, J; Capasso, M; Cinatl, J; Hansson, K; Jemaà, M; Lasorsa, VA; Massoumi, R; Michaelis, M; Sime, W; Strand, D, 2020) |
| "Neuroblastoma is the leading cause of cancer death in children aged 1 to 4 years." | ( Alfón, J; Antonelli, R; Boloix, A; Domènech, C; Erazo, T; Gallego, S; Jiménez, C; Lizcano, JM; Masanas, M; Moreno, L; Muñoz-Guardiola, P; París-Coderch, L; Pérez-Montoyo, H; Roma, J; Sánchez de Toledo, J; Segura, MF; Soriano, A; Yeste-Velasco, M, 2020) |
| "Neuroblastoma is the most common extracranial solid tumor in childhood." | ( Gurunathan, S; Jeyaraj, M; Kang, MH; Kim, JH, 2020) |
| "Neuroblastoma is a common malignancy and frequently affects children, leading to a low survival rate." | ( Wang, J; Xia, S; Yang, B; Ye, X, 2020) |
| "Neuroblastoma is the most common extracranial solid tumor of childhood and is associated with poor survival in high risk patients." | ( Chiu, B; Coburn, JM; Ornell, KJ, 2021) |
| "Neuroblastoma is the second most common pediatric cancer involving the peripheral nervous system in which stage IVS metastatic tumors regress due to spontaneous differentiation." | ( Connell, AJ; Glazewski, L; Halakos, EG; Mason, RW; Wei, S, 2021) |
| "Neuroblastoma is an embryonal malignancy of early childhood arising from the embryonic sympatho-adrenal lineage of the neural crest." | ( Cimetta, E; Esposito, MR; Frasson, C; Fusco, P; Mattiuzzo, E; Tonini, GP; Viola, G, 2021) |
| "Neuroblastoma is a childhood malignancy and in the majority of patients, the primary tumor arises in one of the adrenal glands." | ( Adema, GJ; Boon, L; Brok, IC; Hoogerbrugge, PM; Kroesen, M; Reijnen, D; van den Bijgaart, RJE; Wassink, M, 2020) |
| "Neuroblastoma is the most common solid malignant tumor in infants and young children." | ( Akbari-Birgani, S; Khademy, M; Madadi, Z; Mohammadi, S; Mousavi, SA, 2021) |
| "Neuroblastoma is a deadly and serious malignancy among children." | ( Hosseinzadeh, A; Kamali, M; Mehrzadi, S; Pourhanifeh, MH, 2021) |
| "Neuroblastoma is the most common childhood extracranial solid malignancy." | ( Connor, JR; Lee, SY; Schengrund, CL; Slagle-Webb, B; Zhu, J, 2021) |
| "Neuroblastomas are tumors of the sympathetic nervous system that arise from the sympathetic trunk and adrenal glands." | ( Körber, F; Schäfer, JF, 2021) |
| "Neuroblastoma is the third most common pediatric cancer composed of malignant immature cells that are usually treated pharmacologically by all trans-retinoic acid (ATRA) but sometimes, they can spontaneously differentiate into benign forms." | ( Atmani, H; Buchbinder, N; Labat, B; Ladam, G; Morin-Grognet, S; Vannier, JP, 2021) |
| "Neuroblastomas are childhood tumors with frequent fatal relapses after induction treatment, which is related to tumor evolution with additional genomic events." | ( Dolman, MEM; Drost, J; Ebus, ME; Essing, AHW; Hakkert, A; Helleday, T; Hoyng, LL; Koopmans, B; Koster, J; Molenaar, JJ; Molenaar, P; Oka, R; Schild, L; van Boxtel, R; van den Boogaard, ML; van Gerven, MR; Versteeg, R; Zwijnenburg, DA, 2021) |
| "Neuroblastoma is the most common extracranial solid tumour in childhood, originated from cells of the neural crest during the development of the Sympathetic Nervous System." | ( Brum, MO; Brum, PO; Gasparotto, J; Gelain, DP; Krolow, R; Moreira, JCF; Saibro-Girardi, C; Tiefensee-Ribeiro, C; Viola, GD, 2022) |
| "Paediatric neuroblastoma is a relatively common type of malignant tumour originating from neural crest tissues." | ( Chen, M; Li, J; Liu, X; Wang, J; Wang, X, 2021) |
| "Neuroblastoma is a common solid tumor of childhood and is often associated with hypertension." | ( Blydt-Hansen, T; Deyell, RJ; Harding, M, 2022) |
| "Neuroblastoma is a severe childhood disease, accounting for ~10% of all infant cancers." | ( Ascanelli, C; Boi, D; Capelli, D; Carpinelli, P; Contestabile, R; Costi, R; De Leo, A; Di Santo, R; Guarguaglini, G; Lindon, C; Marini, G; Montanari, R; Paiardini, A; Pochetti, G; Polverino, F; Saviano, M; Souvalidou, F; Tramonti, A; Trisciuoglio, D, 2021) |
| "Neuroblastoma is primarily an embryonal tumor of infancy." | ( Feulefack, J; Khan, A; Sergi, CM, 2022) |
| "Neuroblastoma is a deadly childhood cancer arising in the developing sympathetic nervous system." | ( Alexandrou, S; Caldon, CE; Davis, TP; De Preter, K; Deng, N; Dodson, E; Fletcher, J; Holliday, H; Kamili, A; Kavallaris, M; Marshall, GM; McCarroll, J; Mestdagh, P; Nikolic, I; Simpson, KJ; Swarbrick, A; Wheatley, M; Yang, J, 2022) |
| "Neuroblastoma is the most common extracranial solid malignancy of childhood." | ( Al-Zeer, MA; Arlt, B; Berg, J; Deubzer, HE; Kurreck, J; Röhrs, V; Wu, D, 2021) |
| "Neuroblastomas are one of the most common types of solid tumors in infants and children and are responsible for approximately 15% of childhood cancer deaths." | ( Angeles, C; Enzor, LA; Levesque, AA; Pappalardo, RM; Puli, P, 2022) |
| "Neuroblastomas are very rare tumors in adults, with thoracic or mediastinal locations being especially uncommon." | ( Azari, FS; Deshpande, C; Kennedy, GT; Sande, CM; Singhal, S; Surrey, LF, 2022) |
| "Neuroblastoma is a common extracranial solid tumor of childhood." | ( He, H; Xu, Q; Yu, C, 2022) |
| "Neuroblastoma is the most common paediatric solid tumour and prognosis remains poor for high-risk cases despite the use of multimodal treatment." | ( Balcells, C; Benito, A; Carling, D; Chesler, L; da Costa, BM; Eckold, C; Gruet, M; Herendi, L; Jamin, Y; Keun, HC; Kramer, H; Liu, Y; Ma, Y; Montoya, A; Nijhuis, A; Poon, E; Sikka, A; Valbuena, GN; Want, EJ; Wickremesinghe, C; Xu, Y; Yogev, O, 2022) |
| "Neuroblastoma is a rare disease." | ( Bilang, R; Bruder, E; Gros, SJ; Holland-Cunz, S; Huo, Z; Martin, I; Muraro, MG; Supuran, CT; von der Weid, N, 2022) |
| "Neuroblastoma is the most common extracranial solid tumor of childhood, with heterogeneous clinical manifestations ranging from spontaneous regression to aggressive metastatic disease." | ( Carcaboso, AM; Ecker, RC; Garcia, M; Gómez-González, S; Gonçalves-Alves, E; Lavarino, C; Mateo-Lozano, S; Mora, J; Muñoz-Aznar, O; Rodríguez-Hernández, CJ; Suñol, M, 2022) |
| "Neuroblastoma is a deadly childhood cancer, and MYCN-amplified neuroblastoma (MNA-NB) patients have the worst prognoses and are therapy-resistant." | ( Amadesi, C; Angelucci, S; Bartolucci, D; Bortolotti, S; Cerisoli, L; Fischer, M; Hrelia, P; Lampis, S; Martelli, AM; Montemurro, L; Nieddu, G; Paganelli, F; Pasquinelli, G; Pession, A; Raieli, S; Scardovi, AL; Tonelli, R; Valente, S, 2022) |
| "Neuroblastoma is the most common extracranial malignant solid tumor during childhood." | ( Chainansamit, SO; Chotsampancharoen, T; Hongeng, S; Kanjanapongkul, S; Komvilaisak, P; Monsereenusorn, C; Photia, A; Phuakpet, K; Pongphitcha, P; Rujkijyanont, P; Sanpakit, K; Sathitsamitphong, L; Seksarn, P; Suwannaying, K; Techavichit, P; Traivaree, C; Wiangnon, S; Winaichatsak, A, 2022) |
| "Neuroblastoma is the most common solid tumor in children." | ( Arslan, ME; Çelikezen, FÇ; Firat, M; Öner, S; Türkez, H, 2022) |
| "Neuroblastoma is the most common extracranial solid tumor in early childhood." | ( Chen, H; Guo, Y; Hao, Y; Hou, C; Jia, Y; Li, J; Li, N; Liu, J; Liu, Y; Yan, X; Yang, L; Zhang, N, 2022) |
| "Neuroblastoma is the most frequently diagnosed extracranial solid tumor in children and accounts for 7 % of all childhood malignancies and 15 % cancer mortality in children." | ( Badea, I; Camargo Zittlau, I; Diedrich, C; Maissar Khalil, N; Mara Mainardes, R; Schineider Machado, C; Taise Fin, M, 2022) |
| "Neuroblastoma is a type of developmental childhood cancer that arises from the neural crest." | ( Cai, A; Gao, K; Jiang, Y; Li, X; Lin, Z; Liu, N; Wang, J; Wu, Y, 2022) |
| "Neuroblastoma is the most common and deadliest tumor in infancy." | ( Bai, F; Cao, Y; Han, QL; Li, K; Lin, WH; Mei, LH; Ren, PX; Wang, L; Zhang, XL, 2023) |
| "Neuroblastoma is a common extracranial tumor with about 50% 5-year survival rate in high-risk children." | ( Chen, IC; Chen, YC; Fu, MH; Hung, CY; Lee, CW; Tain, YL; Weng, JR; Wu, CW; Wu, KLH, 2022) |
| "Neuroblastoma is a common solid cancer in young children with poor clinical outcomes following conventional chemotherapy." | ( Carter, DR; Cheng, NC; Cheung, BB; Chung, SA; Dilda, PJ; Fletcher, JI; Gifford, A; Haber, M; Hogg, PJ; Kim, PY; Kleynhans, A; Liu, T; Luo, JS; Marshall, GM; Mayoh, C; Mittra, R; Murray, J; Nagy, Z; Norris, MD; Rahmanto, AS; Salib, A; Seneviratne, JA; Sun, C; Sutton, SK; Tan, O; Wang, Q; Xue, C; Zhang, L; Zhang, Y, 2023) |
| "Neuroblastoma is one of the most common malignancies in childhood, accounts for approximately 7% of all malignancies." | ( Babu, CK; Grishina, M; Khatri, DK; Kumar, R; Madan, J; Mourya, A; Novak, J; Pathak, P; Pingle, P; Sainaga Jyothi, VGS; Singh, PK; Singh, SB; Veerabomma, H; Verma, A, 2023) |
| "Neuroblastoma is one of the most common malignancies in childhood, accounts for approximately 7% of all malignancies." | ( Babu, CK; Grishina, M; Khatri, DK; Kumar, R; Madan, J; Mourya, A; Novak, J; Pathak, P; Pingle, P; Sainaga Jyothi, VGS; Singh, PK; Singh, SB; Veerabomma, H; Verma, A, 2023) |
| "Neuroblastoma is one of the most common malignancies in childhood, accounts for approximately 7% of all malignancies." | ( Babu, CK; Grishina, M; Khatri, DK; Kumar, R; Madan, J; Mourya, A; Novak, J; Pathak, P; Pingle, P; Sainaga Jyothi, VGS; Singh, PK; Singh, SB; Veerabomma, H; Verma, A, 2023) |
| "Neuroblastoma is the most common malignant tumor in childhood, and metastases occur in more than 30% patients." | ( Chen, H; Huang, M; Jiang, R; Liu, W; Shi, Y; Wang, T; Yang, M; Zhang, S, 2023) |
| "Neuroblastoma is one of the most common solid tumors in children younger than 1 year of age, with poor prognosis and survival rates." | ( Erdogan, MA; Yılmaz, OA, 2023) |
| "Neuroblastoma is one of the most common childhood solid tumors." | ( Aoki, H; Aoyama, M; Hayashi, H; Inoue, Y; Izumi, K; Kakita, H; Takeshita, S; Ueda, H; Yamada, Y, 2023) |
| "Neuroblastoma is the most common extracranial malignant tumor in childhood." | ( Brenneisen, P; Ebbert, L; Klahm, NP; Reichert, AS; Stahl, W; von Montfort, C; Wenzel, CK, 2023) |
| "Neuroblastoma is one of the common extracranial tumors in children (infants to 2 years), accounting for 8 ~ 10% of all malignant tumors." | ( Chen, C; Gao, W; Guo, J; Jiang, Y; Liu, G; Tian, T; Wang, J; Xiao, L; Yang, B; Zhang, W; Zhao, Y, 2023) |
| "Neuroblastoma is the most common tumour in children under 1 year old, accounting for 12-15% of childhood cancer deaths." | ( Balachandar, A; Bhagirath, E; Pandey, S; Vegh, C; Wear, D, 2023) |
| "Neuroblastoma is a challenging pediatric tumor with a need for improved treatment strategies." | ( Li, X; Wang, J; Zhu, A, 2023) |
| "Neuroblastoma is a paediatric cancer that is characterised by poor prognosis for chemoresistant disease, highlighting the need for better treatment options." | ( Birkhold, M; Braun, Y; Brücher, D; Cinatl, J; Demes, MC; Gradhand, E; Gretser, S; Jacob, M; Jeroch, J; Michaelis, M; Pieper, NM; Rothweiler, F; Särchen, V; Vogler, M; Wiedemann, S, 2023) |
| Excerpt | Reference |
|---|
| "Clinical chemotherapy in the treatment of neuroblastoma is undergoing further evaluation." | ( Chu, TM; Keogh, B; Moore, RH; Murphy, GP; Williams, P, 1976) |
| "Our results suggest that pretreating neuroblastoma patients with IFN-gamma before MIBG administration may enhance the efficacy of both biologically targeted radioimaging and therapy of this tumor." | ( Carbone, R; Cornaglia-Ferraris, P; Montaldo, PG; Ponzoni, M, 1992) |
| "Chronic treatment of neuroblastoma x glioma NG108-15 hybrid cells with the opioid agonist D-Ala,2 D-Leu5-enkephalin (DADLE) induces a homologous desensitization of the delta opioid receptors present in these cells." | ( Hom, DS; Law, PY; Loh, HH, 1991) |
| "We have treated human neuroblastoma cells with various complexes of aluminium, over a range of concentrations, and have measured the amount of aluminium entering the cells after one week, using atomic absorption spectroscopy." | ( Day, JP; Guy, SP; Itzhaki, RF; Seabright, P, 1990) |
| "Chronic opioid treatment of neuroblastoma x glioma NG108-15 cells induces desensitization of the opioid receptor and this may involve a change in membrane protein phosphorylation." | ( Bass, ES; Law, PY; Loh, HH; Louie, AK; Zhan, J, 1990) |
| "In untreated active neuroblastoma DOPA or ALAAD (10 out of 10) or both (six out of 10) were clearly elevated." | ( Ausema, L; Boomsma, F; Hahlen, K; Hakvoort-Cammel, FG; Krenning, EP; Man in't Veld, AJ; Oosterom, R; Schalekamp, MA, 1989) |
| "Chronic treatment of neuroblastoma X glioma NG108-15 hybrid cells with 10 nM [D-Ala2,D-Leu5] enkephalin (DADLE) results in a reduction of cell-surface opiate delta receptors." | ( Law, PY; Loh, HH; Louie, AK, 1985) |
| "Chronic treatment of neuroblastoma X glioma NG108-15 hybrid cells with opiate agonist resulted in loss of the acute opiate inhibition of adenylate cyclase activity with a concomitant increase in the enzymatic activity observable on addition of the antagonist naloxone." | ( Griffin, MT; Law, PY; Loh, HH, 1986) |
| "Chronic treatment of neuroblastoma X glioma hybrid cells (NG 108-15) with the muscarinic cholinergic agonist carbachol, which acutely inhibits adenylate cyclase, resulted in a 104 +/- 10% increase in PGE1-stimulated cAMP accumulation." | ( Hoffman, BB; Thomas, JM, 1986) |
| "A 4 year-old child being treated for neuroblastoma developed erythroblastopenia." | ( Bayle, C; Gardrat, B; Lemerle, J; Mielot, F; Tchernia, G, 1985) |
| "Chronic etorphine treatment of neuroblastoma X glioma NG108-15 cells results in both an increase in adenylate cyclase activity (upon addition of the opiate antagonist naloxone) as well as an homologous desensitization of the opiate receptor." | ( Griffin, MT; Law, PY; Loh, HH, 1985) |
| "When NI kinase was added to heat-treated neuroblastoma nuclei in the presence of [gamma-32P] ATP, two proteins with apparent subunit molecular weights of 11,000 and 10,000 were prominently phosphorylated." | ( Chen, KY; Verma, R, 1986) |
| "By contrast, patients successfully treated for neuroblastoma, as well as patients with a variety of other tumors or diseases, do not show cystathioninuria." | ( Efron, ML; Geiser, CF, 1968) |
| "Chronic treatment of neuroblastoma X glioma NG108-15 hybrid cells with the opiate agonist etorphine resulted in a decrease in both opiate receptor density (receptor down-regulation) and opiate ability to inhibit prostaglandin E1 (PGE1)-stimulated increases in cyclic AMP levels (receptor desensitization)." | ( Hom, DS; Law, PY; Loh, HH, 1983) |
| "Eighteen cDNAs, cloned from interferon-treated T98G neuroblastoma cells, correspond to seven different mRNAs induced up to 40-fold by interferon." | ( Friedman, RL; Kerr, IM; Manly, SP; McMahon, M; Stark, GR, 1984) |
| "[131I]MIBG as a treatment agent in neuroblastoma." | ( Cunningham, S; Gaze, MN; Mairs, RJ; O'Donoghue, JA; Owens, J; Russell, J; Vaidyanathan, G; Zalutsky, MR, 1995) |
| "The mRNA for CRABPI is present in untreated human neuroblastoma cells, whereas the mRNA for CRABPII is induced in cells treated with either all-trans RA or 9-cis RA." | ( Clagett-Dame, M; Plum, LA, 1995) |
| "Successful imaging or treatment of neuroblastoma with 131I-meta-iodobenzylguanidine (131I-mIBG) depends on the selectivity of active (type 1) uptake of mIBG in neuroblastoma cells relative to passive (type 2) uptake present in most normal tissues." | ( Armour, A; Gaze, MN; Mairs, RJ; Wheldon, TE, 1994) |
| "Neither RA-treated nor untreated neuroblastoma cells expressed IL-1 beta, granulocyte-macrophage colony stimulating factor, or tumor necrosis factor-alpha mRNA." | ( Cheng, SN; Shaio, MF; Wu, NC; Yang, KD, 1993) |
| "While the presence of NCAM on these treated murine neuroblastoma cells is evidence for 'differentiation' along neuronal lines, the isoform complement and cell surface distribution of NCAM in treated cells are not normal." | ( Lowengrub, JA; Schor, NF, 1993) |
| "In this study, we show that RA treatment of neuroblastoma cells induces the expression of TrkB, the receptor for the neurotrophins BDNF, NT-3, and NT-4/5." | ( Kaplan, DR; Lucarelli, E; Matsumoto, K; Thiele, CJ, 1993) |
| "A 6-day treatment of neuroblastoma cells with RU486 eliminated the inhibitory effect morphine exerts on the intracellular accumulation of cyclic AMP induced by prostaglandin E1." | ( Casulari, LA; Maggi, R; Martini, L; Pimpinelli, F; Piva, F, 1996) |
| "GDNF treatment of neuroblastoma cells also results in increased transcription of an Elk luciferase reporter gene, suggesting that GDNF activates the mitogen-activated protein kinase signal transduction pathway." | ( Chao, HH; Dixon, JE; Seasholtz, AF; Vega, QC; Worby, CA; Zhao, Y, 1996) |
| "To assess the effect of treatment of neuroblastoma, 131I-MIBG scintigraphy was considered more useful than MRI." | ( Hino, M; Kawabe, J; Kobashi, T; Koda, M; Ochi, H; Okamura, T; Yamada, R, 1997) |
| "Protein kinase C (PKC) activation after treatment of human neuroblastoma SK-N-BE(2)C cells with phorbol 12-myristate 13-acetate (PMA) was found to enhance transcription of the human dopamine beta-hydroxylase (DBH) in those cells." | ( Chae, HD; Kim, JS; Kim, KT; Nam, JS, 1997) |
| "Angiostatic treatment of neuroblastoma is a new and theoretically promising treatment modality that merits clinical investigations." | ( Christofferson, R; Wassberg, E, 1997) |
| "131I MIBG has been used as palliative treatment of neuroblastoma patients with recurrent or persistent disease who failed other modalities of treatment." | ( Heyman, S; Tepmongkol, S, 1999) |
| "Phosphatase treatment of neuroblastoma nuclear extracts reduces FAC1 DNA binding affinity." | ( Bowser, R; Dragich, JM; Jordan-Sciutto, KL, 1999) |
| "Here we show 17beta-oestradiol treatment of neuroblastoma and rat embryo neurones in culture blocks the increase in nip-2 mRNA induced by apoptotic stimuli and prevents cell death as indicated by cell counting, 3,(4,5-dimethylthiazol-2-yl)2,5-diphenil-tetrazoliumbromi de and DNA fragmentation assays." | ( Ciana, P; Maggi, A; Meda, C; Patrone, C; Pellicciari, C; Pollio, G; Vegeto, E, 2000) |
| "Further, treatment of human neuroblastoma SH-SY5Y cells with retinoic acid results in the cells withdrawing from the cell cycle and extending neurites, in the same time frame that tissue transglutaminase expression significantly increases." | ( Johnson, GV; Lesort, M; Tucholski, J, 2001) |
| "Pervanadate treatment of N2a neuroblastoma cells resulted in tyrosine phosphorylation and association of endogenous APP and Shc A." | ( D'Adamio, L; Pelicci, G; Pelicci, PG; Roncarati, R; Tarr, PE, 2002) |
| "In untreated neuroblastoma NB-2a cells, CacyBP is phosphorylated on a serine residue(s), but exists in the dephosphorylated form in BAPTA/AM-treated cells." | ( Filipek, A; Hetman, M; Jastrzebska, B; Kuznicki, J; Kwiatkowska, K; Nowotny, M; Surmacz, L; Wyroba, E, 2002) |
| "Forty patients who had received treatment for neuroblastomas were included in the study." | ( Kikkawa, M; Kubota, T; Nakamura, T; Nishimura, T; Okuyama, C; Ushijima, Y, 2002) |
| "The long term treatment of neuroblastoma cells with quercetin and resveratrol enhanced the differentiation state of the cells." | ( Escher, F; Melzig, MF, 2002) |
| "Cytotoxic drug treatment of neuroblastoma often leads to the development of drug resistance and may be associated with increased malignancy." | ( Blaheta, R; Cinatl, J; Hernáiz Driever, P; Karaskova, J; Klingebiel, T; Kotchetkov, R; Squire, J; Vogel, JU, 2003) |
| "The HSV-tk/GCV system was effective in treating SH-SY5Y neuroblastoma cell line in vivo as well." | ( Bi, X; Zhang, JZ, 2003) |
| "After pretreating human neuroblastoma cells with different concentrations of mI, fluoxetine, or imipramine, receptor function was measured by second messenger [3H]-IPx accumulation and [35S]-GTPgammaS binding to G alpha(q) protein." | ( Brink, CB; de Kock, SE; Harvey, BH; Stein, DJ; Viljoen, SL, 2004) |
| "Zinc was used to treat SH-SY5Y neuroblastoma cells and effects investigated in relation to PKB, p70S6K, and ERK1/2 in the absence and presence of the pro-apoptotic agent staurosporine (STS)." | ( An, WL; Cowburn, RF; Nishimura, T; Pei, JJ; Winblad, B, 2005) |
| "This study shows that sequential treatment of two neuroblastoma cell lines with BL1521, an HDACi, and dFdC resulted in strong antagonism despite a minor increase of dFdCTP incorporation into the DNA of one cell line." | ( Caron, HN; de Ruijter, AJ; Hoebink, J; Leen, R; van Kuilenburg, AB, 2006) |
| "Children treated for neuroblastoma with 131I-MIBG, chemotherapy and surgery were seen to be at risk from developing irreversible thyroid function loss, thyroid nodules, hypergonadotropic hypogonadism, and growth retardation." | ( de Kraker, J; van Santen, HM; Vulsma, T, 2005) |
| "Retinoic acid treatment of two neuroblastoma cell lines upregulated the expression of both APLP2 and ADAM10, thus leading to an increased release of soluble APLP2." | ( Endres, K; Fahrenholz, F; Mueller, U; Postina, R; Schroeder, A, 2005) |
| "Furthermore, treatment of neuroblastoma cells with LfcinB induced cleavage of caspase-6, -7 and -9 followed by cell death." | ( Berge, G; Eliassen, LT; Flaegstad, T; Johnsen, JI; Kogner, P; Leknessund, A; Lindin, I; Løkke, C; Ponthan, F; Rekdal, Ø; Sveinbjørnsson, B; Wikman, M, 2006) |
| "Previously, we have reported that pretreatment of human neuroblastoma SH-SY5Y cells with Apo enhances protection against 6-hydroxydopamine (6-OHDA)-induced cell death." | ( Adachi, T; Hara, H; Ohta, M, 2006) |
| "To determine how cBN affects cells, we treated human neuroblastoma cells (NB-1) and human articular chondrocytes (nHAC-kn) with different concentrations of cBN powder and assessed cell growth and cell survival using the methyl-thiazol-tetrazolium (MTT) assay and a fluorescence probe assay." | ( Fujishita, O; Hata, Y; Hirosaki, K; Kaji, A; Koga, K; Ogura, T; Shintani, K, 2006) |
| "Bortezomib-treated neuroblastoma cells were arrested at G2/M and underwent apoptosis (mean percentage of apoptotic cells in four neuroblastoma cell lines treated with 20 nM bortezomib for 24 hours ranged from 20% to 35%, and caspases were activated by two- to fivefold with respect to untreated cells)." | ( Brignole, C; Cilli, M; Cioni, M; Corrias, MV; Di Paolo, D; Marimpietri, D; Nico, B; Pagnan, G; Pastorino, F; Pezzolo, A; Piccardi, F; Pistoia, V; Ponzoni, M; Ribatti, D, 2006) |
| "In vitro, treatment of a neuroblastoma cell line with nifurtimox resulted in decreased cell viability whereas no effect was seen on an endothelial cell line." | ( Forman, E; Greenlaw, C; Kalkunte, S; McCarten, K; Saulnier Sholler, GL, 2006) |
| "After the treatment of human neuroblastoma SH-SY5Y cells with retinoic acid for 24 h, the expression of c-Ret receptor tyrosine kinase was greatly elevated." | ( Fujita, S; Matsumoto, K; Miyake, J; Miyake, M; Nomura, T; Uebersax, L; Yamada, S, 2007) |
| "Combined treatment of neuroblastoma cells and neuroblastoma-bearing mice with vinblastine and rapamycin induced the down-modulation of both vascular endothelial growth factor production and vascular endothelial growth factor receptor 2 expression." | ( Brignole, C; Cilli, M; Di Paolo, D; Longo, L; Marimpietri, D; Nico, B; Pagnan, G; Pastorino, F; Perri, P; Pezzolo, A; Piccardi, F; Ponzoni, M; Ribatti, D, 2007) |
| "After treatment of human neuroblastoma cells with CDDO-Me, cell cycle studies show depletion of the S-phase, while apoptosis studies show conformational activation and mitochondrial translocation of Bax protein, as well as activation of caspases -3 and -8." | ( Alabran, JL; Cheuk, A; Khan, J; Leskov, KS; Letterio, J; Liby, K; Sporn, M, 2008) |
| "Clinical use of retinoids in the treatment of neuroblastoma is of interest due to their success in management of acute promyelocytic leukemia." | ( Cardozo, ZA; Cole, MP; Coleman, MC; Cook, C; Kiningham, KK; Spitz, DR; Stewart, JC; Tassone, M, 2008) |
| "DFMO treatment of neuroblastoma-prone genetically engineered mice (TH-MYCN) extended tumor latency and survival in homozygous mice and prevented oncogenesis in hemizygous mice." | ( Buxton, A; Cheng, NC; Davis, K; Evageliou, NF; Gilmour, SK; Guo, R; Haber, M; Hayes, CS; Hogarty, MD; Keating, J; Liu, X; London, WB; Marshall, GM; Murray, J; Norris, MD; Pawel, B; Sekyere, E; Smith, J; Sutton, R; Thomas, W; Venn, N; Zhao, H, 2008) |
| "We previously showed that treating human neuroblastoma (NB) cells with the ODC inhibitor alpha-difluoromethylornithine (DFMO) depleted polyamine pools and induced G1 cell cycle arrest without causing apoptosis." | ( Bachmann, AS; Borsics, T; Koomoa, DL; Wallick, CJ; Yco, LP, 2008) |
| "Using 6-hydroxydopamine (6-OHDA)-treated human neuroblastoma SH-SY5Y cells as a PD cell model, we found that 6-OHDA can cause neuronal death by regulating the activity of STAT3." | ( Chan, P; Wang, L; Xu, S; Xu, X, 2009) |
| "Despite extensive efforts to treat unfavorable neuroblastoma, survival rate of children with the disease is among the lowest." | ( Hicks, SL; Ikegaki, N; Kung, B; Tang, XX; Zhao, H, 2009) |
| "To evaluate our hypothesis, we treated mouse neuroblastoma N2a cells with LA 30 min before the cells were exposed to bupivacaine." | ( Cheng, Y; Ding, Z; Li, C; Liu, L; Wang, X; Zhang, W; Zhang, X, 2010) |
| "Our findings suggest that pretreatment of neuroblastoma cells with LA protected neural cells from bupivacaine-induced injury." | ( Cheng, Y; Ding, Z; Li, C; Liu, L; Wang, X; Zhang, W; Zhang, X, 2010) |
| "Both CI-1033 and erlotinib treatment of neuroblastoma xenograft tumors resulted in decreased tumor growth in vivo, although CI-1033 was more effective." | ( Hughes, DP; Richards, KN; Speleman, F; Trevino, J; Van Roy, N; Zage, PE; Zweidler-McKay, PA, 2010) |
| "Our recent work demonstrated that treatment of neuroblastoma with triptolide causes apoptotic cell death in vitro and decreases tumor size in vivo." | ( Antonoff, MB; Borja-Cacho, D; Chugh, R; Clawson, KA; Dudeja, V; Saluja, AK; Skube, SJ; Vickers, SM, 2010) |
| "In this study, we have treated two neuroblastoma cell lines, SH-SY5Y and LA-N-1, with the spermine analogue N1, N11-Diethylnorspermine (DENSPM)." | ( Alm, K; Holst, CM; Oredsson, SM; Söderstjerna, E, 2010) |
| "We determined that treating human neuroblastoma NB69 cells with the long-lived NO donor 2,2'-(hydroxynitrosohydrazono)bis-ethanimine (DETA/NO) and monitoring the non-apoptotic adherent cell population significantly increases the presentation of N-glycans as detected by concanavalin A." | ( André, S; Gabius, HJ; Van de Wouwer, M; Villalobo, A, 2011) |
| "Furthermore, treatment of neuroblastoma cells with CTS induced the co-translocation of ADAM10 and PKC-α to the cell membrane, the site at which AβPP was cleaved, and this translocation was significantly reduced by GÖ6976." | ( Chung, SK; Durairajan, SS; Huang, JD; Koo, I; Li, M; Liu, LF; Lu, JH; Maruyama, K, 2011) |
| "Identical results were obtained by treatment of the neuroblastoma cell lines with the small molecule BCL2 inhibitor ABT263, which is currently being clinically evaluated." | ( Caron, HN; den Hartog, IJ; Ebus, ME; Koster, J; Lamers, F; Molenaar, JJ; Ora, I; Schild, L; Versteeg, R; Westerhout, EM, 2012) |
| "In vitro, MK-2206 treatment inhibited neuroblastoma cell proliferation, which was accompanied by a cell line selective G(1) arrest of cell cycle or production of ROS." | ( Attayan, N; Li, Z; Ramalingam, S; Thiele, CJ; Yan, S, 2012) |
| "In the present study, we treated two human neuroblastoma cell lines [SK-N-SH and SK-N-Be(2)C] with progressively increasing doses of doxorubicin under two conditions: with and without vorinsotat co-therapy." | ( Chu, F; Clark, S; Jafari, N; Jie, C; Lautz, TB; Madonna, MB; Naiditch, JA; Qiu, YY; Zheng, X, 2012) |
| "Importantly, treatment of neuroblastoma mouse xenografts with PEGylated hCGL-NLV resulted in near complete cessation of tumor growth." | ( Cheung, NK; Ekerdt, B; Georgiou, G; Hu, J; Paley, O; Stone, E, 2012) |
| "Temozolomide is an attractive candidate treatment in neuroblastoma with methylated MGMT, especially in central nervous system relapsed cases." | ( Marutsuka, K; Moritake, H; Nunoi, H; Shimonodan, H; Takeshima, H; Yamada, A; Yokogami, K, 2013) |
| "Early identification and treatment of neuroblastoma, the most common malignant solid tumor in infants, (Atkinson et al." | ( Bhargava, R; Rezaimehr, Y, 2013) |
| "A major obstacle in the effective treatment of neuroblastoma is the development of multidrug resistance (MDR)." | ( Bright, SA; Butini, S; Campiani, G; Carroll, E; Lennon, JC; O'Meara, A; Williams, DC; Zisterer, DM, 2014) |
| "Similarly, MLN8237 treatment decreased neuroblastoma tumorigenicity in vitro." | ( Chung, DH; Kim, KW; Lee, S; Paul, P; Qiao, J; Romain, C, 2014) |
| "The effective treatment of neuroblastoma remains one of the major challenges in pediatric oncology." | ( Bao, P; Chen, K; Li, Y; Liu, Y; Sun, X; Wang, J; Wang, Y; Zhang, J; Zhou, B; Zhou, Z, 2014) |
| "MIBG is an effective component in treatment of neuroblastoma." | ( Behfar, M; Beiki, D; Eftekhari, M; Fallahi, B; Fard-Esfahani, A; Ghavamzadeh, A; Hamidieh, AA; Hosseini, AS; Paragomi, P; Shamshiri, A, 2014) |
| "Conclusions Treatment of neuroblastoma tumor cells with EMD1214063 inhibits HGF-induced c-Met phosphorylation and results in cell death." | ( Hicks, J; Scorsone, K; Woodfield, SE; Zage, PE; Zhang, L, 2014) |
| "In this study, we show that treatment of neuroblastoma cell lines with 1-15 μM imatinib resulted in a dose dependent inhibition of 5-bromo-2'-deoxyuridine (BrdU) incorporation into newly synthesized DNA." | ( Buccinnà, B; Lupino, E; Piccinini, M; Ramondetti, C, 2014) |
| "TMZ may be an effective agent for treatment of neuroblastoma as a single or in combination with other drugs." | ( Avcı, ÇB; Çıtışlı, V; Dodurga, Y; Eroğlu, C; Şatıroğlu-Tufan, NL; Seçme, M, 2015) |
| "We found that ethanol treatment of neuroblastoma cells increased MDK and ALK expression." | ( Chen, H; He, D; Lasek, AW; Muramatsu, H, 2015) |
| "Chemotherapeutic regimens used for the treatment of Neuroblastoma (NB) cause long-term side effects in pediatric patients." | ( Basha, R; Bowman, WP; Eslin, D; Kenyon, LE; Sankpal, UT; Shelake, S; Sutphin, RM; Tabor-Simecka, L; Vishwanatha, JK; Wadwani, A, 2015) |
| "Fascinatingly, treatment of neuroblastoma neuro-2a and NB41A3 cells with honokiol for 12 h did not affect cell autophagy or apoptosis but caused significant suppression of cell migration." | ( Chang, YA; Chen, RM; Lin, CJ; Wang, JJ; Wang, W; Yeh, PS, 2016) |
| "Sulfite may be an effective agent for treatment of neuroblastoma as a single agent or in combination with other agents." | ( Avcı, ÇB; Bağcı, G; Dodurga, Y; Eroğlu, C; Gündoğdu, G; Küçükatay, V; Lale Şatıroğlu-Tufan, N; Seçme, M, 2015) |
| "(131) I-MIBG is increasingly used for treating neuroblastoma; however, administration requires careful adherence to radiation safety guidelines." | ( DuBois, SG; Gustafson, C; Hawkins, R; Lee, JS; Matthay, K; Roy-Burman, A; Wong, T; Wu, R, 2016) |
| "Twenty-one patients were treated: 19 with neuroblastoma and 2 with MP." | ( Carrasquillo, JA; Cheung, NK; Kramer, K; Kushner, BH; Larson, SM; Modak, S; Pandit-Taskar, N; Zanzonico, P, 2016) |
| "Herein, we treated neuroblastoma SH-SY5Y cells with physiologically and pharmacologically relevant concentrations of 2-methoxyestradiol." | ( Gorska, M; Kuban-Jankowska, A; Milczarek, R; Wozniak, M, 2016) |
| "We show that following retinoic acid treatment, human neuroblastoma cells, SiMa and SH-SY5Y, acquire a neuronal phenotype evidenced by axonal growth and expression of neuronal markers." | ( Binz, T; Davletov, B; Leese, C; Rust, A, 2016) |
| "However, treating mouse neuroblastoma-derived NB2a cells with TCE resulted in the down regulation of the SOD1 protein and elevated oxidative stress under conditions where SOD1 production was suppressed." | ( Fujii, J; Fujii, S; Fujiwara, H; Goto, K; Homma, T; Hozumi, Y; Ito, J; Kaneko, K; Konno, T; Kurahashi, T; Otsuki, N; Shichiri, M; Takashima, M; Yoshida, Y, 2016) |
| "Results Ponatinib treatment of neuroblastoma cells resulted in decreased cell viability and migration in vitro." | ( Du, M; Patel, K; Smith, V; Whittle, SB; Woodfield, SE; Zage, PE; Zhang, L, 2016) |
| "Here, treatment of neuroblastoma cells with oxyresveratrol (OXYRES), a natural antioxidant, led to dose-dependent cell death and increased autophagic flux along with activation of caspase-dependent apoptosis." | ( Bishayee, K; Huh, SO; Rahman, MA; Sadra, A, 2017) |
| "GSK461364 treatment of neuroblastoma cell lines reduced cell viability and proliferative capacity, caused cell cycle arrest and massively induced apoptosis." | ( Ackermann, S; Althoff, K; Astrahantseff, K; Batzke, K; Deubzer, HE; Eggert, A; Fischer, M; Heukamp, L; Künkele, A; Lindner, S; Odersky, A; Pajtler, KW; Sadowski, N; Schäfers, S; Schönbeck, K; Schramm, A; Schulte, JH; Sprüssel, A; Thor, T, 2017) |
| "Importantly, treatment of neuroblastoma cells with pharmacological modulators of [Ca2+]i-regulating proteins in combination with CDDP or TOPO increased cytotoxicity." | ( Büsselberg, D; Florea, AM; Gopinath, N; Helmy, I; Mahgoub, S; McCallum, JE; Reifenberger, G; Sass, S; Theis, FJ; Varghese, E; Varghese, S, 2017) |
| "Eventually, after long-term treatment, all neuroblastoma cells undergo cell death." | ( Bayer, T; Gunkel, N; Heimburg, T; Jung, M; Koeneke, E; Kolbinger, FR; Miller, AK; Müller, M; Oehme, I; Ridinger, J; Sippl, W; Westermann, F; Witt, O, 2018) |
| "In this work, we treated the human neuroblastoma SH-SY5Y cell line with the diterpene carnosic acid (CA) at 1 μM for 12 h prior to the exposure to GLU for further 24 h." | ( Andrade, CMB; Chenet, AL; de Almeida, FJS; de Oliveira, MR; Duarte, AR, 2019) |
| "Despite advances in the treatment of neuroblastoma, patients with high-risk disease still have dismal survival prognosis." | ( Bierbrauer, A; Fulda, S; Jacob, M; Vogler, M, 2020) |
| "Clinical first‑line drugs for treating neuroblastoma have been developed over the previous half‑century; however, progress in the identification of new drugs with high efficiency is required." | ( Bi, A; Nie, L; Pan, L; Tan, Z; Wu, Y; Wu, Z; Yao, S; Ye, Y, 2020) |
| "Neural differentiation leads to the treatment of neuroblastoma by halting the cell and tumor growth and consequently its expansion." | ( Akbari-Birgani, S; Khademy, M; Madadi, Z; Mohammadi, S; Mousavi, SA, 2021) |
| "In this study, we used 50 μM FB1-treated SH-SY5Y neuroblastoma cells to elucidate the signaling pathway of FB1-induced parthanatos." | ( Bhardwaj, M; Chauhan, AK; Jakhar, R; Kang, SC; Paul, S, 2021) |
| "Thus, we treated the human neuroblastoma SH-SY5Y cells with ISO (0." | ( Brasil, FB; Dall'Oglio, EL; de Almeida, FJS; de Oliveira, MR; Luckachaki, MD, 2022) |
| "In the present study, treatment of the neuroblastoma cell line SH-SY5Y with vitamin B12 resulted in elevated levels of phosphatidylcholine, phosphatidylethanolamine, sphingomyelin, and plasmalogens." | ( Erhardt, VKJ; Griebsch, LV; Grimm, HS; Grimm, MOW; Haas, EC; Hartmann, T; Janitschke, D; Kuppler, KN; Lauer, AA; Portius, D; Radermacher, J; Theiss, EL; Walzer, O, 2022) |
| "For the treatment of neuroblastoma, the use of lipoplatin seems to be beneficial in reducing side effects of cisplatin." | ( Aktas, S; Aktaş, TÇ; Altun, Z; Eskicioğlu, HE; Kırkım, G; Kolatan, E; Olgun, N; Olgun, Y; Serinan, E; Yılmaz, O, 2022) |
| "A total of 27 children with heavily pretreated neuroblastoma (12 with refractory disease, 14 with relapsed disease, and 1 with a complete response at the end of first-line therapy) were enrolled and received GD2-CART01." | ( Abbas, R; Abbaszadeh, Z; Algeri, M; Amicucci, M; Bertaina, V; Bonetti, F; Bugianesi, R; Caruana, I; Cefalo, MG; Colafati, GS; De Angelis, B; De Ioris, MA; Del Baldo, G; Del Bufalo, F; Di Cecca, S; Folsi, V; Galaverna, F; Garganese, MC; Guercio, M; Gunetti, M; Iacovelli, S; Iaffaldano, L; Leone, G; Li Pira, G; Locatelli, F; Macchia, S; Mastronuzzi, A; Merli, P; Pagliara, D; Perruccio, K; Quintarelli, C; Rabusin, M; Serra, A; Sinibaldi, M; Villani, MF, 2023) |
| "To answer this question, we treated neuroblastoma cells using evernyl-based menadione-triazole hybrids (6a-6i) or RA or both and examined the differentiation of neuroblastoma cells." | ( Bhadra, MP; Dutta, H; Jain, N; Makani, VKK; Mendonza, JJ; Reddy, ST; Uppuluri, VM, 2023) |
| "We pretreated the human neuroblastoma SH-SY5 cells with the extract and AgNPs and evaluated the neuroprotective activity of these agents against methamphetamine (Meth) cytotoxicity." | ( Dogani, M; Khorrami, S; Mahani, SE; Moghaddam, MM; Taheri, RA, 2023) |
| "Traditional treatments for neuroblastomas are usually ineffective and lead to serious side effects and poor prognoses." | ( Chen, JT; Chen, RM; Chen, TH; Liu, SH; Sun, DP; Yang, ST, 2023) |
| "Nonetheless, the impact of lycorine treatment on neuroblastoma has not yet been investigated." | ( Jiang, X; Lu, X; Quan, M; Tang, J; Xia, Y; Xiang, X; Zhao, Z, 2023) |
| "Administering HHT to treat neuroblastoma resulted in effective cell elimination in vitro and tumor reduction in vivo." | ( Cheng, YS; Chien, CY; Chung, YH; Hsieh, CH; Hsu, CH; Hsu, WM; Huang, CT; Huang, HC; Juan, HF; Lee, YH; Liu, YL; Yang, TS, 2023) |