trichlorfon has been researched along with Neuroblastoma in 2 studies
Trichlorfon: An organochlorophosphate cholinesterase inhibitor that is used as an insecticide for the control of flies and roaches. It is also used in anthelmintic compositions for animals. (From Merck, 11th ed)
trichlorfon : A phosphonic ester that is dimethyl phosphonate in which the hydrogen atom attched to the phosphorous is substituted by a 2,2,2-trichloro-1-hydroxyethyl group.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the role of the endoplasmic reticulum pathway in apoptosis induced by trichlorfon in SH-SY5Y human neuroblastoma cells." | 7.75 | Trichlorfon induces apoptosis in SH-SY5Y neuroblastoma cells via the endoplasmic reticulum? ( Chang, PA; Liu, CY; Wu, YJ, 2009) |
| "This study investigated the role of the endoplasmic reticulum pathway in apoptosis induced by trichlorfon in SH-SY5Y human neuroblastoma cells." | 3.75 | Trichlorfon induces apoptosis in SH-SY5Y neuroblastoma cells via the endoplasmic reticulum? ( Chang, PA; Liu, CY; Wu, YJ, 2009) |
| "We have investigated the acute and chronic effect of metrifonate (MTF) and dichlorvos (DDVP), respectively the prodrug and active acetylcholinesterase inhibitor, on the secretory processing of the amyloid precursor protein (APP) in SH-SY5Y neuroblastoma cells." | 3.71 | Short- and long-term effect of acetylcholinesterase inhibition on the expression and metabolism of the amyloid precursor protein. ( Caprera, A; Govoni, S; König, G; Racchi, M; Sironi, M, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, CY | 1 |
| Chang, PA | 1 |
| Wu, YJ | 1 |
| Racchi, M | 1 |
| Sironi, M | 1 |
| Caprera, A | 1 |
| König, G | 1 |
| Govoni, S | 1 |
2 other studies available for trichlorfon and Neuroblastoma
| Article | Year |
|---|---|
Trichlorfon induces apoptosis in SH-SY5Y neuroblastoma cells via the endoplasmic reticulum?
Topics: Apoptosis; Blotting, Western; Calcium; Cell Line, Tumor; Cholinesterase Inhibitors; Endoplasmic Reti | 2009 |
Short- and long-term effect of acetylcholinesterase inhibition on the expression and metabolism of the amyloid precursor protein.
Topics: Acetylcholinesterase; Amyloid beta-Protein Precursor; Atropine; Carbachol; Cholinesterase Inhibitors | 2001 |