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phenoxybenzamine and Neuroblastoma

phenoxybenzamine has been researched along with Neuroblastoma in 6 studies

Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"Preoperative alpha- and beta-adrenergic receptor block with phenoxybenzamine and labetalol, the intraoperative course of a 4-month-old infant with neuroblastoma and elevated catecholamines causing sweating, hypertension, and tachycardia, are presented."3.75Catecholamine-secreting neuroblastoma in a 4-month-old infant: perioperative management. ( Hernandez, MR; Seefelder, C; Shamberger, RC, 2009)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hernandez, MR1
Shamberger, RC1
Seefelder, C1
El-Fakahany, E2
Richelson, E2
Lopez, JR1
Ahlquist, RP1
Pertsemlidis, D1
Gitlow, SE1
Kark, AE1
Schega, W1

Reviews

1 review available for phenoxybenzamine and Neuroblastoma

ArticleYear
Pheochromocytoma: advances in diagnosis and treatment.
    Surgery annual, 1972, Volume: 4

    Topics: Adrenal Gland Neoplasms; Catecholamines; Child; Creatinine; Diagnosis, Differential; Epinephrine; Fe

1972

Other Studies

5 other studies available for phenoxybenzamine and Neuroblastoma

ArticleYear
Catecholamine-secreting neuroblastoma in a 4-month-old infant: perioperative management.
    Journal of clinical anesthesia, 2009, Volume: 21, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Catecholamines; Female; Humans; Hypertens

2009
Phenoxybenzamine and dibenamine interactions with calcium channel effectors of the muscarinic receptor.
    Molecular pharmacology, 1981, Volume: 20, Issue:3

    Topics: Animals; Binding, Competitive; Calcium; Carbachol; Cells, Cultured; Cyclic GMP; Dibenzylchlorethamin

1981
Lanthanum binding to murine neuroblastoma cells.
    Journal of neurochemistry, 1983, Volume: 40, Issue:6

    Topics: Animals; Atropine; Carbachol; Cell Line; Cell Membrane; Dibenzylchlorethamine; Electron Probe Microa

1983
Present state of alpha and beta adrenergic drugs. II. The adrenergic blocking agents.
    American heart journal, 1976, Volume: 92, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Cardiovascular System; Humans; Neuroblast

1976
[Surgery of adrenal medulla].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1969, Volume: 40, Issue:7

    Topics: Adolescent; Adrenal Gland Neoplasms; Adrenal Medulla; Adult; Blood Pressure Determination; Catechola

1969