Page last updated: 2024-10-28

ethidium and Neuroblastoma

ethidium has been researched along with Neuroblastoma in 6 studies

Ethidium: A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
ethidium : The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
" We try to prevent the apoptosis induced by rotenone toxicity with 50 microM myricetin, 100 microM fraxetin and 100 microM N-acetylcysteine (NAC) that protect against reactive oxygen species (ROS), on SH-SY5Y human neuroblastoma cell line."7.72Neuroprotective effect of fraxetin and myricetin against rotenone-induced apoptosis in neuroblastoma cells. ( Andres, D; Benedi, J; Cascales, M; Molina-Jiménez, MF; Sánchez-Reus, MI, 2004)
" We try to prevent the apoptosis induced by rotenone toxicity with 50 microM myricetin, 100 microM fraxetin and 100 microM N-acetylcysteine (NAC) that protect against reactive oxygen species (ROS), on SH-SY5Y human neuroblastoma cell line."3.72Neuroprotective effect of fraxetin and myricetin against rotenone-induced apoptosis in neuroblastoma cells. ( Andres, D; Benedi, J; Cascales, M; Molina-Jiménez, MF; Sánchez-Reus, MI, 2004)
" We describe the creation of respiratory-deficient SH-SY5Y neuroblastoma cell lines (rho zero 64/5) by selectively depleting mitochondrial DNA through prolonged exposure to ethidium bromide."3.69Creation and characterization of mitochondrial DNA-depleted cell lines with "neuronal-like" properties. ( Davis, RE; Miller, SW; Parker, WD; Trimmer, PA, 1996)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's3 (50.00)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Molina-Jiménez, MF1
Sánchez-Reus, MI1
Andres, D1
Cascales, M1
Benedi, J1
Lin, CH1
Chen, SS1
Lin, YC1
Lee, YS1
Chen, TJ1
Song, SL1
Chueh, SH1
Miller, SW1
Trimmer, PA1
Parker, WD1
Davis, RE1
Suh, BC1
Lee, IS1
Chae, HD1
Han, S1
Kim, KT1
Yang, SS1
Wivel, NA1

Other Studies

6 other studies available for ethidium and Neuroblastoma

ArticleYear
Neuroprotective effect of fraxetin and myricetin against rotenone-induced apoptosis in neuroblastoma cells.
    Brain research, 2004, May-29, Volume: 1009, Issue:1-2

    Topics: Acetylcysteine; Analysis of Variance; Apoptosis; Blotting, Southern; Cell Line, Tumor; Cell Survival

2004
Germanium dioxide induces mitochondria-mediated apoptosis in Neuro-2A cells.
    Neurotoxicology, 2006, Volume: 27, Issue:6

    Topics: Acridine Orange; Analysis of Variance; Animals; Antimutagenic Agents; Apoptosis; bcl-2-Associated X

2006
Antagonistic effect of Na+ and Mg2+ on P2z purinoceptor-associated pores in dibutyryl cyclic AMP-differentiated NG108-15 cells.
    Journal of neurochemistry, 1996, Volume: 67, Issue:4

    Topics: Adenosine Triphosphate; Affinity Labels; Animals; Aorta; Bucladesine; Calcium; Cell Differentiation;

1996
Creation and characterization of mitochondrial DNA-depleted cell lines with "neuronal-like" properties.
    Journal of neurochemistry, 1996, Volume: 67, Issue:5

    Topics: Blood Platelets; Cell Differentiation; Cell Line; Cell Line, Transformed; Citrate (si)-Synthase; DNA

1996
Characterization of Mas-7-induced pore formation in SK-N-BE(2)C human neuroblastoma cells.
    Molecules and cells, 1998, Apr-30, Volume: 8, Issue:2

    Topics: Calcium; Cell Membrane; Dose-Response Relationship, Drug; Enzyme Activation; Ethidium; Extracellular

1998
Analysis of high-molecular-weight ribonucleic acid associated with intracisternal A particles.
    Journal of virology, 1973, Volume: 11, Issue:2

    Topics: Animals; Bone Marrow Cells; Carbon Isotopes; Cell Line; Cells, Cultured; Centrifugation, Density Gra

1973