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gallopamil and Neuroblastoma

gallopamil has been researched along with Neuroblastoma in 5 studies

Gallopamil: Coronary vasodilator that is an analog of iproveratril (VERAPAMIL) with one more methoxy group on the benzene ring.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"The action of verapamil, /+/-D600 and nisoldipine on the inward calcium current (ICa) was studied in mouse neuroblastoma x rat glioma hybrid cells of the line 108CC5 under voltage clamp conditions by means of a suction pipette method."7.67Inhibition of calcium channels in neuroblastoma x glioma hybrid cells by verapamil, D600, diltiazem and nisoldipine. ( Bodewei, R; Hering, S; Schubert, B; Wollenberger, A, 1987)
"The action of verapamil, /+/-D600 and nisoldipine on the inward calcium current (ICa) was studied in mouse neuroblastoma x rat glioma hybrid cells of the line 108CC5 under voltage clamp conditions by means of a suction pipette method."3.67Inhibition of calcium channels in neuroblastoma x glioma hybrid cells by verapamil, D600, diltiazem and nisoldipine. ( Bodewei, R; Hering, S; Schubert, B; Wollenberger, A, 1987)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atlas, D1
Adler, M1
Freedman, SB1
Miller, RJ1
Galper, JB1
Catterall, WA1
Eckert, R1
Trautwein, W1
Bodewei, R1
Hering, S1
Schubert, B1
Wollenberger, A1

Other Studies

5 other studies available for gallopamil and Neuroblastoma

ArticleYear
alpha-adrenergic antagonists as possible calcium channel inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brain; Calcium; Cell Line; Cell Membran

1981
Calcium channel activation: a different type of drug action.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:17

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1984
Inhibition of sodium channels by D600.
    Molecular pharmacology, 1979, Volume: 15, Issue:1

    Topics: Binding, Competitive; Calcium; Cells, Cultured; Gallopamil; Ion Channels; Myocardium; Neoplasms, Exp

1979
Inhibitory modulation of fast and slow Ca(2+)-currents in neuroblastoma x glioma cells during differentiation.
    Neuroscience letters, 1991, Aug-05, Volume: 129, Issue:1

    Topics: Animals; Calcium Channels; Cell Differentiation; Enkephalin, Leucine-2-Alanine; Gallopamil; Glioma;

1991
Inhibition of calcium channels in neuroblastoma x glioma hybrid cells by verapamil, D600, diltiazem and nisoldipine.
    Biomedica biochimica acta, 1987, Volume: 46, Issue:8-9

    Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Gallopamil; Glioma; Ion Channels; Neuroblasto

1987