Page last updated: 2024-08-17

levodopa and Neuroblastoma

levodopa has been researched along with Neuroblastoma in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19907 (21.21)18.7374
1990's8 (24.24)18.2507
2000's7 (21.21)29.6817
2010's8 (24.24)24.3611
2020's3 (9.09)2.80

Authors

AuthorsStudies
Fujita, K; Inoue, S; Ito, S; Yamamoto, Y1
Eriksson, H; Rössler, OG; Thiel, G1
Bhuvanendran, S; Magalingam, KB; Radhakrishnan, AK; Ramdas, P; Selvaduray, KR; Somanath, SD1
Haertlé, T; Jafarkhani, S; Meratan, AA; Muronetz, V; Saboury, AA; Zohoorian-Abootorabi, T1
Choi, SM; Kim, BC; Nguyen, DT; Samidurai, M; Song, J1
Abdullah, R; Basak, I; Larsen, JP; Lee, S; Møller, SG; Patil, KS1
Ji, C; Liu, Y; Ren, Z; Wang, T; Yang, N; Zheng, J; Zuo, P1
Davidson, DF; Dow, E; Kelly, AU; Srivastava, R1
Feng, LR; Maguire-Zeiss, KA1
Arning, E; Bottiglieri, T; Nunbhakdi-Craig, V; Sontag, E; Sontag, JM; Wasek, B1
Colamartino, M; Cornetta, T; Cozzi, R; Leone, S; Meneghini, C; Padua, L; Testa, A1
Ho, A; Peritore, CS; Schaus, SE; Yamamoto, BK1
Asanuma, M; Emdadul Haque, M; Higashi, Y; Miyazaki, I; Ogawa, N; Tanaka, K1
Jankovic, J; Le, W; Pan, T1
Benghuzzi, H; Martin, TM; Tucci, M2
Giasson, BI; Ischiropoulos, H; Lynch, DR; Mazzulli, JR; Mishizen, AJ; Nagatsu, T; Nakashima, A; Ota, A; Thomas, SA1
Fujita, K; Inoue, S; Ito, S1
de Yébenes, JG; Mena, MA; Pardo, B1
Fahn, S; García de Yébenes, J; Mena, MA; Pardo, B1
Lai, CT; Yu, PH2
Appel, SH; Jankovic, J; Le, W; Rowe, DB; Xie, W; Zou, L1
Sampaio-Maia, B; Soares-da-Silva, P1
Canals, S; Casarejos, MJ; de Bernardo, S; Handler, A; Mena, MA; Rodríguez-Martín, E1
de Vries, JA; Fremouw-Ottevangers, DC; Muskiet, FA; van der Meulen, J; Wolthers, BG1
Wick, MM1
de Vries, JA; Fremouw-Ottevangers, DC; Muskiet, FA; Nagel, GT; Wolthers, BG1
Casarejos, MJ; Fahn, S; García de Yébenes, J; Mena, MA; Pardo, B1
Bartsch, O; Busse, E; Kornhuber, B1
Darchen, F; Henry, JP; Horellou, P; Mallet, J; Marlier, L; Privat, A; Scherman, D1
Abeling, NG; Overmars, H; van Gennip, AH; Voûte, PA1
McGrath, PC; Neifeld, JP1

Other Studies

33 other study(ies) available for levodopa and Neuroblastoma

ArticleYear
Synthesis and antitumor activity of cysteinyl-3,4-dihydroxyphenylalanines and related compounds.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cricetinae; Cysteinyldopa; Dihydroxyphenylalanine; Humans; Leukemia L1210; Male; Melanoma; Mice; Neoplasms, Experimental; Neuroblastoma

1981
Tyrosine hydroxylase gene promoter activity is upregulated in female catecholaminergic neuroblastoma cells following activation of a Gαq-coupled designer receptor.
    Neurochemistry international, 2022, Volume: 160

    Topics: Calcineurin; Chromatin; EGF Family of Proteins; Extracellular Signal-Regulated MAP Kinases; Female; GTP Phosphohydrolases; GTP-Binding Proteins; Histone Acetyltransferases; Humans; Levodopa; Nerve Growth Factors; Neuroblastoma; Phospholipases; Receptors, G-Protein-Coupled; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tyrosine 3-Monooxygenase

2022
Tocotrienol-Rich Fraction and Levodopa Regulate Proteins Involved in Parkinson's Disease-Associated Pathways in Differentiated Neuroblastoma Cells: Insights from Quantitative Proteomic Analysis.
    Nutrients, 2022, Nov-03, Volume: 14, Issue:21

    Topics: Chromatography, Liquid; Humans; Levodopa; Neuroblastoma; Parkinson Disease; Proteomics; Tandem Mass Spectrometry; Tocotrienols; Vitamin E

2022
Modulation of cytotoxic amyloid fibrillation and mitochondrial damage of α-synuclein by catechols mediated conformational changes.
    Scientific reports, 2023, 03-31, Volume: 13, Issue:1

    Topics: alpha-Synuclein; Amyloid; Amyloidogenic Proteins; Catechols; Humans; Levodopa; Neuroblastoma; Parkinson Disease

2023
Levodopa (L-DOPA) attenuates endoplasmic reticulum stress response and cell death signaling through DRD2 in SH-SY5Y neuronal cells under α-synuclein-induced toxicity.
    Neuroscience, 2017, 09-01, Volume: 358

    Topics: alpha-Synuclein; bcl-2-Associated X Protein; Cell Death; Cell Line, Tumor; CREB-Binding Protein; Disks Large Homolog 4 Protein; Dopamine Agents; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; Humans; Iron-Regulatory Proteins; Levodopa; Neuroblastoma; Neurons; NF-kappa B; Receptors, Dopamine D2; RNA, Messenger; Signal Transduction

2017
PARK13 regulates PINK1 and subcellular relocation patterns under oxidative stress in neurons.
    Journal of neuroscience research, 2014, Volume: 92, Issue:9

    Topics: Cell Line, Tumor; Cytoskeleton; Dopamine Agents; Gene Expression Regulation; Humans; Hydrogen Peroxide; Levodopa; Mutation; Neuroblastoma; Neurons; Oxidants; Oxidative Stress; Parkinson Disease; Protein Kinases; RNA, Messenger; Subcellular Fractions; Time Factors; Transfection

2014
Neuroprotective effects of 5-(4-hydroxy-3-dimethoxybenzylidene)-thiazolidinone in MPTP induced Parkinsonism model in mice.
    Neuropharmacology, 2015, Volume: 93

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Animals, Newborn; Benzylidene Compounds; Cells, Cultured; Disease Models, Animal; Levodopa; Male; Membrane Potential, Mitochondrial; Mesencephalon; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Proteins; MPTP Poisoning; Neuroblastoma; Neurons; Neuroprotective Agents; Neurotoxins; Psychomotor Performance; rho GTP-Binding Proteins; Thiazolidinediones; Time Factors; Tyrosine 3-Monooxygenase

2015
L-DOPA therapy interferes with urine catecholamine analysis in children with suspected neuroblastoma: a case series.
    Annals of clinical biochemistry, 2017, Volume: 54, Issue:5

    Topics: Artifacts; Catecholamines; Child, Preschool; Humans; Infant; Levodopa; Neuroblastoma; Urinalysis

2017
Dopamine and paraquat enhance α-synuclein-induced alterations in membrane conductance.
    Neurotoxicity research, 2011, Volume: 20, Issue:4

    Topics: alpha-Synuclein; Analysis of Variance; Animals; Cell Line, Tumor; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Doxycycline; Drug Interactions; Gene Expression Regulation; Green Fluorescent Proteins; Heme Oxygenase-1; Herbicides; Humans; Levodopa; Membrane Potentials; Mice; Nerve Tissue Proteins; Neuroblastoma; Paraquat; Patch-Clamp Techniques; Permeability; Tetrazolium Salts; Thiazoles; Transfection; Tubulin; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins

2011
Acute administration of L-DOPA induces changes in methylation metabolites, reduced protein phosphatase 2A methylation, and hyperphosphorylation of Tau protein in mouse brain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Jul-04, Volume: 32, Issue:27

    Topics: Animals; Antiparkinson Agents; Brain; Cell Line, Tumor; Dopaminergic Neurons; Humans; Levodopa; Male; Methylation; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neuroblastoma; Phosphorylation; Primary Cell Culture; Protein Phosphatase 2; tau Proteins

2012
Protective effects of L-dopa and carbidopa combined treatments on human catecholaminergic cells.
    DNA and cell biology, 2012, Volume: 31, Issue:11

    Topics: Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Cell Line, Tumor; Cell Survival; Comet Assay; DNA Damage; Dopa Decarboxylase; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Levodopa; Neuroblastoma; Oxidants; Oxidative Stress; Reactive Oxygen Species; Time Factors

2012
Resveratrol attenuates L-DOPA-induced hydrogen peroxide toxicity in neuronal cells.
    Neuroreport, 2012, Dec-05, Volume: 23, Issue:17

    Topics: Antioxidants; Catechin; Cell Line, Tumor; Cell Survival; Drug Evaluation, Preclinical; Drug Interactions; Fibroblasts; Fluoresceins; Humans; Hydrogen Peroxide; Levodopa; Monoamine Oxidase; Nerve Tissue Proteins; Neuroblastoma; Neurons; Neuroprotective Agents; Oxidative Stress; Quercetin; Resveratrol; Stilbenes; Tyrosine; Tyrosine 3-Monooxygenase

2012
Apoptosis-inducing neurotoxicity of dopamine and its metabolites via reactive quinone generation in neuroblastoma cells.
    Biochimica et biophysica acta, 2003, Jan-02, Volume: 1619, Issue:1

    Topics: Apoptosis; Benzoquinones; Caspase 3; Caspases; Catalase; Catechols; Dopamine; Enzyme Activation; Glutathione; Humans; Hydrogen Peroxide; In Situ Nick-End Labeling; Levodopa; Neuroblastoma; Superoxide Dismutase; Tumor Cells, Cultured

2003
Slowing Parkinson's disease progression: recent dopamine agonist trials.
    Neurology, 2004, Jan-27, Volume: 62, Issue:2

    Topics: Antiparkinson Agents; Benzothiazoles; Biological Transport; Cell Line, Tumor; Clinical Trials as Topic; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Humans; In Vitro Techniques; Indoles; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuroblastoma; Parkinson Disease; Pramipexole; Thiazoles

2004
The effect of conventional and sustained delivery of levodopa on SH-SY5Y neuroblastoma cells.
    Biomedical sciences instrumentation, 2005, Volume: 41

    Topics: Antiparkinson Agents; Cell Line, Tumor; Cell Proliferation; Cell Size; Cell Survival; Delayed-Action Preparations; Dose-Response Relationship, Drug; Humans; Levodopa; Neuroblastoma

2005
The effect of conventional and sustained delivery of thymoquinone and levodopa on SH-SY5Y human neuroblastoma cells.
    Biomedical sciences instrumentation, 2006, Volume: 42

    Topics: Antiparkinson Agents; Benzoquinones; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hydrogen Peroxide; Levodopa; Neuroblastoma; Neuroprotective Agents; Treatment Outcome

2006
Cytosolic catechols inhibit alpha-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Sep-27, Volume: 26, Issue:39

    Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Amino Acid Substitution; Animals; Catechols; Cell Differentiation; Cell Line, Tumor; Cerebral Cortex; Corpus Striatum; Cytosol; Dopamine; Humans; Levodopa; Mice; Mice, Transgenic; Mutation, Missense; Nerve Degeneration; Neuroblastoma; Oxidation-Reduction; Parkinson Disease; Parkinsonian Disorders; Protein Conformation; Recombinant Fusion Proteins; Solubility; Transfection; Tretinoin; Tyrosine 3-Monooxygenase

2006
The mechanism of toxicity of 5-S-cysteinyldopa to tumour cells. Hydrogen peroxide as a mediator of cytotoxicity.
    Biochemical pharmacology, 1983, Jul-01, Volume: 32, Issue:13

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cysteinyldopa; Dihydroxyphenylalanine; Dopamine; Humans; Hydrogen Peroxide; Levodopa; Male; Mice; Neoplasms, Experimental; Neuroblastoma; Oxidation-Reduction

1983
L-dopa inhibits complex IV of the electron transport chain in catecholamine-rich human neuroblastoma NB69 cells.
    Journal of neurochemistry, 1995, Volume: 64, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Ascorbic Acid; Brain; Catecholamines; Electron Transport; Electron Transport Complex IV; Humans; Levodopa; NAD(P)H Dehydrogenase (Quinone); Neuroblastoma; Rats; Tumor Cells, Cultured

1995
Ascorbic acid protects against levodopa-induced neurotoxicity on a catecholamine-rich human neuroblastoma cell line.
    Movement disorders : official journal of the Movement Disorder Society, 1993, Volume: 8, Issue:3

    Topics: Ascorbic Acid; Brain; Brain Neoplasms; Catecholamines; Cell Line; Drug Interactions; Female; Humans; Levodopa; Male; Neuroblastoma; Parkinson Disease; Quinones; Selegiline

1993
R(-)-deprenyl potentiates dopamine-induced cytotoxicity toward catecholaminergic neuroblastoma SH-SY5Y cells.
    Toxicology and applied pharmacology, 1997, Volume: 142, Issue:1

    Topics: Antioxidants; Dopamine; Drug Synergism; Humans; Levodopa; Monoamine Oxidase Inhibitors; Neuroblastoma; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Pargyline; Propylamines; Reactive Oxygen Species; Selegiline; Tumor Cells, Cultured

1997
Dopamine- and L-beta-3,4-dihydroxyphenylalanine hydrochloride (L-Dopa)-induced cytotoxicity towards catecholaminergic neuroblastoma SH-SY5Y cells. Effects of oxidative stress and antioxidative factors.
    Biochemical pharmacology, 1997, Feb-07, Volume: 53, Issue:3

    Topics: Ascorbic Acid; Catalase; Cell Survival; Deferoxamine; Dopamine; Levodopa; Lipid Peroxidation; Neuroblastoma; Oxidative Stress; Superoxide Dismutase; Tumor Cells, Cultured; Vitamin E

1997
Neuroprotection by pramipexole against dopamine- and levodopa-induced cytotoxicity.
    Life sciences, 1999, Volume: 64, Issue:15

    Topics: Animals; Benzothiazoles; Cell Line; Cell Survival; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Glioma; Hybrid Cells; Kinetics; Levodopa; Neuroblastoma; Neuroprotective Agents; Pramipexole; Thiazoles

1999
Ca2+/calmodulin mediated pathways regulate the uptake of L-DOPA in mouse neuroblastoma neuro 2A cells.
    Life sciences, 2000, Nov-17, Volume: 67, Issue:26

    Topics: Animals; Biological Transport; Calcium; Calmodulin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Kinetics; Levodopa; Mice; Neuroblastoma; Neurons; Protein Kinase C; Protein Kinases; Tumor Cells, Cultured

2000
L-DOPA and glia-conditioned medium have additive effects on tyrosine hydroxylase expression in human catecholamine-rich neuroblastoma NB69 cells.
    Journal of neurochemistry, 2001, Volume: 78, Issue:3

    Topics: Antioxidants; Apoptosis; Ascorbic Acid; bcl-X Protein; Buthionine Sulfoximine; Carbidopa; Cell Differentiation; Culture Media, Conditioned; Culture Media, Serum-Free; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Humans; Immunoblotting; Immunohistochemistry; In Situ Nick-End Labeling; Levodopa; Neuroblastoma; Neuroglia; Neurons; Proto-Oncogene Proteins c-bcl-2; Time Factors; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase

2001
Determination of some L-3,4-dihydroxyphenylalanine and dopamine metabolites in urine by means of mass fragmentography.
    Clinical chemistry, 1978, Volume: 24, Issue:1

    Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Adult; Aging; Child; Child, Preschool; Dihydroxyphenylalanine; Dopamine; Flavoring Agents; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; Infant; Infant, Newborn; Lactates; Levodopa; Middle Aged; Neuroblastoma; Phenylethyl Alcohol

1978
L-Dopa methyl ester: prolongation of survival of neuroblastoma-bearing mice after treatment.
    Science (New York, N.Y.), 1978, Feb-17, Volume: 199, Issue:4330

    Topics: Animals; Benserazide; Cell Line; Drug Synergism; Leucine; Levodopa; Male; Mice; Neoplasms, Experimental; Neuroblastoma; Thymidine; Uridine

1978
Determination of 3-methoxy-4-hydroxyphenylpyruvic acid, 3,4-dihydroxyphenylethylene glycol, and 3,4-dihydroxyphenylmandelic acid in urine by mass fragmentography, with use of deuterium-labeled internal standards.
    Clinical chemistry, 1978, Volume: 24, Issue:11

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Catechols; Child; Child, Preschool; Deuterium; Dopamine; Ethylene Glycols; Gas Chromatography-Mass Spectrometry; Humans; Infant; Infant, Newborn; Levodopa; Mandelic Acids; Methoxyhydroxyphenylglycol; Middle Aged; Neuroblastoma; Parkinson Disease; Phenylpyruvic Acids; Pheochromocytoma; Reference Standards; Reference Values; Shock, Cardiogenic

1978
Neurotoxicity of levodopa on catecholamine-rich neurons.
    Movement disorders : official journal of the Movement Disorder Society, 1992, Volume: 7, Issue:1

    Topics: Catecholamines; Cell Line; Cell Survival; Dopamine; Dose-Response Relationship, Drug; Humans; Levodopa; Neuroblastoma; Neurons; Selegiline

1992
Non-myelotoxic antitumour effects of L-dopa, buthionine sulphoximine and tamoxifen on neuroblastoma cells in vitro and in vivo.
    Journal of cancer research and clinical oncology, 1991, Volume: 117, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antineoplastic Agents; Buthionine Sulfoximine; Cell Survival; Cyclic AMP; Glutathione; Humans; Levodopa; Male; Methionine Sulfoximine; Mice; Mice, Nude; Monophenol Monooxygenase; Neuroblastoma; Tamoxifen; Tumor Cells, Cultured

1991
Exogeneous expression of L-dopa and dopamine in various cell lines following transfer of rat and human tyrosine hydroxylase cDNA: grafting in an animal model of Parkinson's disease.
    Progress in brain research, 1990, Volume: 82

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; DNA; Dopamine; Enzyme Induction; Graft Survival; Levodopa; Male; Neuroblastoma; Parkinson Disease; Rats; Rats, Inbred Strains; Recombinant Fusion Proteins; Transplantation, Heterotopic; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase

1990
Biochemical monitoring of children with neuroblastoma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1986, Volume: 7, Issue:1

    Topics: Aminoisobutyric Acids; Child; Cystathionine; Dihydroxyphenylalanine; Homovanillic Acid; Humans; Levodopa; Monitoring, Physiologic; Neuroblastoma; Norepinephrine; Prognosis

1986
Inhibition of human neuroblastoma by dopamine antagonists.
    Surgery, 1985, Volume: 98, Issue:2

    Topics: Animals; Cell Division; Cell Line; Domperidone; Dopamine; Dopamine Antagonists; Female; Humans; Levodopa; Mice; Mice, Nude; Neuroblastoma; Pimozide; Receptors, Dopamine; Spiperone

1985