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9-(2-hydroxy-3-nonyl)adenine and Neuroblastoma

9-(2-hydroxy-3-nonyl)adenine has been researched along with Neuroblastoma in 2 studies

9-(2-hydroxy-3-nonyl)adenine: specific inhibitor of adenosine deaminase

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"The uptake of adenosine by an adenosine kinase deficient variant of C1300 murine neuroblastoma cells has been studied in the absence and in the presence of erythro-9-(2-hydroxy-3-nonyl)adenine, a potent adenine deaminase inhibitor."7.66Adenosine transport by a variant of C1300 murine neuroblastoma cells deficient in adenosine kinase. ( Green, RD, 1980)
"The uptake of adenosine by an adenosine kinase deficient variant of C1300 murine neuroblastoma cells has been studied in the absence and in the presence of erythro-9-(2-hydroxy-3-nonyl)adenine, a potent adenine deaminase inhibitor."3.66Adenosine transport by a variant of C1300 murine neuroblastoma cells deficient in adenosine kinase. ( Green, RD, 1980)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Green, RD2

Other Studies

2 other studies available for 9-(2-hydroxy-3-nonyl)adenine and Neuroblastoma

ArticleYear
Effects of exogenous adenosine deaminase and erythro-9-(2-hydroxy-3-nonyl) adenine on intracellular cyclic AMP levels in C1300 murine neuroblastoma in tissue culture.
    Life sciences, 1980, Feb-04, Volume: 26, Issue:5

    Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Cell Line; Culture Techniques; Cyclic AMP; Dipyrid

1980
Adenosine transport by a variant of C1300 murine neuroblastoma cells deficient in adenosine kinase.
    Biochimica et biophysica acta, 1980, May-23, Volume: 598, Issue:2

    Topics: Adenine; Adenosine; Adenosine Kinase; Animals; Biological Transport; Cell Line; Genetic Variation; K

1980