carbonyl cyanide m-chlorophenyl hydrazone has been researched along with Neuroblastoma in 12 studies
Carbonyl Cyanide m-Chlorophenyl Hydrazone: A proton ionophore. It is commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
CCCP : A member of the class of monochlorobenzenes that is benzene substituted by 2-(1,3-dinitrilopropan-2-ylidene)hydrazinyl and chloro groups at positions 1 and 3, respectively. It is a mitochondrial depolarizing agent that induces reactive oxygen species mediated cell death.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study examined the effect of riluzole on [Ca2+]i in IMR32 neuroblastoma cells using fura-2 as a Ca2+ probe." | 7.71 | Effect of the neuroprotective agent riluzole on intracellular Ca2+ levels in IMR32 neuroblastoma cells. ( Chang, CH; Chen, WC; Chow, CK; Jan, CR; Law, YP; Lee, KC; Lu, T; Su, W; Tang, KY; Wang, JL, 2001) |
| "We recently showed that thiamine uptake by neuroblastoma cells is mediated by two saturable transport system: the first with high affinity for thiamine (Km = 35 nM) is blocked by veratridine; the other, with low affinity is blocked by Ca2+." | 7.69 | Thiamine homeostasis in neuroblastoma cells. ( Bettendorff, L, 1995) |
| " This study examined the effect of riluzole on [Ca2+]i in IMR32 neuroblastoma cells using fura-2 as a Ca2+ probe." | 3.71 | Effect of the neuroprotective agent riluzole on intracellular Ca2+ levels in IMR32 neuroblastoma cells. ( Chang, CH; Chen, WC; Chow, CK; Jan, CR; Law, YP; Lee, KC; Lu, T; Su, W; Tang, KY; Wang, JL, 2001) |
| "We recently showed that thiamine uptake by neuroblastoma cells is mediated by two saturable transport system: the first with high affinity for thiamine (Km = 35 nM) is blocked by veratridine; the other, with low affinity is blocked by Ca2+." | 3.69 | Thiamine homeostasis in neuroblastoma cells. ( Bettendorff, L, 1995) |
| " Treatment of fibroblasts (CER) and human neuroblastoma cells (IMR-32) with substances acting on low pH intracellular compartments (methylamine and monensin) prevented rabies virus genome delivery in the cytosol." | 3.68 | Effect of inhibitors of cytoplasmic structures and functions on rabies virus infection in vitro. ( Conti, C; Divizia, M; Orsi, N; Pana, A; Superti, F, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Iriondo, MN | 1 |
| Etxaniz, A | 1 |
| Varela, YR | 1 |
| Ballesteros, U | 1 |
| Hervás, JH | 1 |
| Montes, LR | 1 |
| Goñi, FM | 1 |
| Alonso, A | 1 |
| Nam, MK | 1 |
| Shin, HA | 1 |
| Han, JH | 1 |
| Park, DW | 1 |
| Rhim, H | 1 |
| Gómez-Sánchez, R | 1 |
| Gegg, ME | 2 |
| Bravo-San Pedro, JM | 1 |
| Niso-Santano, M | 1 |
| Alvarez-Erviti, L | 1 |
| Pizarro-Estrella, E | 1 |
| Gutiérrez-Martín, Y | 1 |
| Alvarez-Barrientos, A | 1 |
| Fuentes, JM | 1 |
| González-Polo, RA | 1 |
| Schapira, AH | 2 |
| Ivankovic, D | 1 |
| Chau, KY | 1 |
| Bijur, GN | 1 |
| Jope, RS | 1 |
| Montoya G, JV | 1 |
| Sutachan, JJ | 1 |
| Corrales, A | 1 |
| Xu, F | 1 |
| Blanck, TJ | 1 |
| Recio-Pinto, E | 1 |
| Bettendorff, L | 1 |
| Gérard, V | 1 |
| Rouzaire-Dubois, B | 1 |
| Dubois, JM | 1 |
| Bloc, A | 1 |
| Bugnard, E | 1 |
| Dunant, Y | 1 |
| Falk-Vairant, J | 1 |
| Israël, M | 1 |
| Loctin, F | 1 |
| Roulet, E | 1 |
| Wang, JL | 1 |
| Lee, KC | 1 |
| Tang, KY | 1 |
| Lu, T | 1 |
| Chang, CH | 1 |
| Chow, CK | 1 |
| Chen, WC | 1 |
| Su, W | 1 |
| Law, YP | 1 |
| Jan, CR | 1 |
| Chueh, SH | 1 |
| Liu, JA | 1 |
| Kao, LS | 1 |
| Conti, C | 1 |
| Superti, F | 1 |
| Divizia, M | 1 |
| Pana, A | 1 |
| Orsi, N | 1 |
12 other studies available for carbonyl cyanide m-chlorophenyl hydrazone and Neuroblastoma
| Article | Year |
|---|---|
LC3 subfamily in cardiolipin-mediated mitophagy: a comparison of the LC3A, LC3B and LC3C homologs.
Topics: Autophagy; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cardiolipins; gamma-Aminobutyric Acid; Humans; | 2022 |
Essential roles of mitochondrial depolarization in neuron loss through microglial activation and attraction toward neurons.
Topics: Animals; CA1 Region, Hippocampal; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cells, Cultured; Cocult | 2013 |
Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression.
Topics: Autophagy; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line, Tumor; Gene Expression; Hu | 2014 |
Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy.
Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Carbonyl Cyanide m-Chlorophenyl Hydrazo | 2016 |
Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation.
Topics: Androstadienes; Brain Neoplasms; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Fractionation; Cell | 2003 |
Pulses of extracellular K+ produce two cytosolic Ca2+ transients that display different temperature dependence and carbonyl cyanide m-chlorophenyl sensitivity in SH-SY5Y cells.
Topics: Anticonvulsants; Caffeine; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line, Tumor; Clo | 2008 |
Thiamine homeostasis in neuroblastoma cells.
Topics: Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chromatography, High Pressure Liquid; Homeostasi | 1995 |
Contribution of a H+ pump in determining the resting potential of neuroblastoma cells.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell M | 1994 |
Acetylcholine synthesis and quantal release reconstituted by transfection of mediatophore and choline acetyltranferase cDNAs.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Cadmium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; | 1999 |
Effect of the neuroprotective agent riluzole on intracellular Ca2+ levels in IMR32 neuroblastoma cells.
Topics: Animals; Brefeldin A; Calcium; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydrazone; | 2001 |
Intracellular calcium pools in neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Calcimycin; Calcium; Calcium-Transpor | 1990 |
Effect of inhibitors of cytoplasmic structures and functions on rabies virus infection in vitro.
Topics: Animals; Azides; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line; Colchicine; Cytochalasin B; C | 1990 |