Page last updated: 2024-10-22

am 580 and Neuroblastoma

am 580 has been researched along with Neuroblastoma in 1 studies

Am 580: a selctive retinoic acid receptor (alpha) agonist; structure given in first source
4-{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino}benzoic acid : An amidobenzoic acid obtained by formal condensation of the carboxy group of (5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)benzoic acid with the anilino group of 4-aminobenzoic acid. A selective RARalpha agonist.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"Neuroblastoma is a type of developmental childhood cancer that arises from the neural crest."1.72Neuroblastoma SH-SY5Y Cell Differentiation to Mature Neuron by AM580 Treatment. ( Cai, A; Gao, K; Jiang, Y; Li, X; Lin, Z; Liu, N; Wang, J; Wu, Y, 2022)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Cai, A1
Lin, Z1
Liu, N1
Li, X1
Wang, J1
Wu, Y1
Gao, K1
Jiang, Y1

Other Studies

1 other study available for am 580 and Neuroblastoma

ArticleYear
Neuroblastoma SH-SY5Y Cell Differentiation to Mature Neuron by AM580 Treatment.
    Neurochemical research, 2022, Volume: 47, Issue:12

    Topics: Cell Differentiation; Cell Line, Tumor; Humans; Nerve Tissue Proteins; Neuroblastoma; Neurons; Potas

2022