citalopram has been researched along with Neuroblastoma in 3 studies
Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We assessed and compared the cytotoxicity of 2 SSRI, citalopram and escitalopram, on neuroblastoma cell lines." | 7.85 | Assessment of citalopram and escitalopram on neuroblastoma cell lines. Cell toxicity and gene modulation. ( Aissouni, Y; Chalus, M; Coll, G; Delétage, N; Gobron, S; Sakka, L; Sylvain-Vidal, V, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Rodríguez-Lavado, J | 1 |
| Gallardo-Garrido, C | 1 |
| Mallea, M | 1 |
| Bustos, V | 1 |
| Osorio, R | 1 |
| Hödar-Salazar, M | 1 |
| Chung, H | 1 |
| Araya-Maturana, R | 1 |
| Lorca, M | 1 |
| Pessoa-Mahana, CD | 1 |
| Mella-Raipán, J | 1 |
| Saitz, C | 1 |
| Jaque, P | 1 |
| Reyes-Parada, M | 1 |
| Iturriaga-Vásquez, P | 1 |
| Pessoa-Mahana, H | 1 |
| Sakka, L | 1 |
| Delétage, N | 1 |
| Chalus, M | 1 |
| Aissouni, Y | 1 |
| Sylvain-Vidal, V | 1 |
| Gobron, S | 1 |
| Coll, G | 1 |
| Cinquanta, M | 1 |
| Ratovitski, T | 1 |
| Crespi, D | 1 |
| Gobbi, M | 1 |
| Mennini, T | 1 |
| Simantov, R | 1 |
3 other studies available for citalopram and Neuroblastoma
| Article | Year |
|---|---|
Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antidepressive Agents; Cell | 2020 |
Assessment of citalopram and escitalopram on neuroblastoma cell lines. Cell toxicity and gene modulation.
Topics: Citalopram; Gene Regulatory Networks; Humans; Neural Stem Cells; Neuroblastoma; Selective Serotonin | 2017 |
Carrier-mediated serotonin release induced by d-fenfluramine: studies with human neuroblastoma cells transfected with a rat serotonin transporter.
Topics: Animals; Calcium; Carrier Proteins; Citalopram; Fenfluramine; Humans; In Vitro Techniques; Membrane | 1997 |