normetanephrine has been researched along with Neuroblastoma in 28 studies
Normetanephrine: A methylated metabolite of norepinephrine that is excreted in the urine and found in certain tissues. It is a marker for tumors.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Plasma concentrations of 3-methoxytyramine, normetanephrine, and metanephrine were measured in two pediatric cohorts: (i) 96 children with confirmed neuroblastoma and (ii) 41 children with signs and symptoms of a catecholamine-producing tumor or other neoplasms and in whom neuroblastoma was excluded." | 7.96 | Biochemical testing for neuroblastoma using plasma free 3-O-methyldopa, 3-methoxytyramine, and normetanephrine. ( Berthold, F; Butch, ER; Eisenhofer, G; Furman, WL; Hero, B; Huebner, A; Lovorn, E; Mangelis, A; Peitzsch, M; Santana, VM; Shulkin, BL, 2020) |
| "A substantial number of patients with neuroblastoma (NB) have increased excretion of catecholamines and metanephrines." | 7.91 | Plasma free metanephrines for diagnosis of neuroblastoma patients. ( Barco, S; Cangemi, G; Conte, M; Corrias, MV; de Sain-van der Velden, M; Garaventa, A; Sorrentino, S; Tripodi, G; Tytgat, G; van der Ham, M; van Kuilenburg, A; Verly, I, 2019) |
| "Plasma concentrations of 3-methoxytyramine, normetanephrine, and metanephrine were measured in two pediatric cohorts: (i) 96 children with confirmed neuroblastoma and (ii) 41 children with signs and symptoms of a catecholamine-producing tumor or other neoplasms and in whom neuroblastoma was excluded." | 3.96 | Biochemical testing for neuroblastoma using plasma free 3-O-methyldopa, 3-methoxytyramine, and normetanephrine. ( Berthold, F; Butch, ER; Eisenhofer, G; Furman, WL; Hero, B; Huebner, A; Lovorn, E; Mangelis, A; Peitzsch, M; Santana, VM; Shulkin, BL, 2020) |
| "A substantial number of patients with neuroblastoma (NB) have increased excretion of catecholamines and metanephrines." | 3.91 | Plasma free metanephrines for diagnosis of neuroblastoma patients. ( Barco, S; Cangemi, G; Conte, M; Corrias, MV; de Sain-van der Velden, M; Garaventa, A; Sorrentino, S; Tripodi, G; Tytgat, G; van der Ham, M; van Kuilenburg, A; Verly, I, 2019) |
| "combined determination of normetanephrine with vanillylmandelic acid (0-1 year) or homovanillic acid (1-5 years and 5-10 years) further enhanced the diagnostic power up to 100% sensitivity and specificity of the testing depending on the age group." | 3.72 | Comparative values of catecholamines and metabolites for the diagnosis of neuroblastoma. ( Corcuff, JB; Monsaingeon, M; Perel, Y; Simonnet, G, 2003) |
| "Neuroblastoma is a common solid tumor of childhood and is often associated with hypertension." | 1.72 | Catecholamines in neuroblastoma: Driver of hypertension, or solely a marker of disease? ( Blydt-Hansen, T; Deyell, RJ; Harding, M, 2022) |
| "Mesoblastic nephroma is by far the most frequent intrarenal fetal tumor." | 1.38 | Prenatal intrarenal neuroblastoma mimicking a mesoblastic nephroma: a case report. ( Allal, H; Forgues, D; Galifer, RB; Garnier, S; Guibal, MP; Haouy, S; Kalfa, N; Maillet, O; Sabatier, E; Saguintaah, M; Serre, I, 2012) |
| "Neuroblastomas are malignant tumors derived embryonically from the neural crest." | 1.29 | Urinary excretion of methylated catecholamine metabolites in a child with neuroblastoma maturing into ganglioneuroma. ( Bekri, S; Candito, M; Chambon, P; Deville, A; Soler, C; Thyss, A, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (60.71) | 18.7374 |
| 1990's | 3 (10.71) | 18.2507 |
| 2000's | 2 (7.14) | 29.6817 |
| 2010's | 4 (14.29) | 24.3611 |
| 2020's | 2 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Harding, M | 1 |
| Deyell, RJ | 1 |
| Blydt-Hansen, T | 1 |
| Peitzsch, M | 1 |
| Butch, ER | 1 |
| Lovorn, E | 1 |
| Mangelis, A | 1 |
| Furman, WL | 1 |
| Santana, VM | 1 |
| Hero, B | 1 |
| Berthold, F | 1 |
| Shulkin, BL | 1 |
| Huebner, A | 1 |
| Eisenhofer, G | 1 |
| Barco, S | 1 |
| Verly, I | 1 |
| Corrias, MV | 1 |
| Sorrentino, S | 1 |
| Conte, M | 1 |
| Tripodi, G | 1 |
| Tytgat, G | 1 |
| van Kuilenburg, A | 1 |
| van der Ham, M | 1 |
| de Sain-van der Velden, M | 1 |
| Garaventa, A | 1 |
| Cangemi, G | 1 |
| Miyoshi, T | 2 |
| Tomita, K | 3 |
| Griffin, A | 1 |
| O'Shea, P | 1 |
| FitzGerald, R | 1 |
| O'Connor, G | 1 |
| Tormey, W | 1 |
| Garnier, S | 1 |
| Maillet, O | 1 |
| Haouy, S | 1 |
| Saguintaah, M | 1 |
| Serre, I | 1 |
| Galifer, RB | 1 |
| Forgues, D | 1 |
| Guibal, MP | 1 |
| Allal, H | 1 |
| Sabatier, E | 1 |
| Kalfa, N | 1 |
| Monsaingeon, M | 1 |
| Perel, Y | 1 |
| Simonnet, G | 1 |
| Corcuff, JB | 1 |
| GIUDICELLI, JF | 1 |
| DAUCHY, F | 1 |
| GJESSING, LR | 2 |
| TANIGUCHI, K | 1 |
| KAKIMOTO, Y | 1 |
| ARMSTRONG, MD | 1 |
| Candito, M | 2 |
| Soler, C | 1 |
| Deville, A | 2 |
| Bekri, S | 1 |
| Chambon, P | 2 |
| Thyss, A | 2 |
| Murakami, M | 1 |
| Wang, MT | 1 |
| Yoshioka, M | 1 |
| Imai, K | 1 |
| Tamura, Z | 1 |
| Albertini, M | 1 |
| Politano, S | 1 |
| Mariani, R | 1 |
| Iwaoka, T | 1 |
| Umeda, T | 1 |
| Sato, T | 2 |
| Borud, O | 1 |
| Strobach, H | 1 |
| Greeff, K | 1 |
| Pertsemlidis, D | 1 |
| Gitlow, SE | 2 |
| Kark, AE | 1 |
| Käser, H | 3 |
| Freier, DT | 1 |
| Tank, ES | 1 |
| Harrison, TS | 1 |
| Yoshinaga, K | 1 |
| Jéquier, E | 1 |
| Bertani, LM | 1 |
| Dziedzic, SW | 1 |
| Clarke, DD | 1 |
| Mönch, E | 1 |
| Stefan, H | 1 |
| Türler, K | 1 |
| Burri, PH | 1 |
| Shimbo, S | 1 |
| Anton, AH | 1 |
| Sayre, DF | 1 |
3 reviews available for normetanephrine and Neuroblastoma
| Article | Year |
|---|---|
[Metanephrine (M), normetanephrine (NM) and fractionated metanephrines].
Topics: Adrenal Gland Neoplasms; Autonomic Nervous System Diseases; Biomarkers; Chromatography, High Pressur | 2005 |
[Metanephrine (M) and normetanephrine (NM)].
Topics: Adolescent; Adult; Child; Child, Preschool; Humans; Infant; Metanephrine; Neuroblastoma; Normetaneph | 1999 |
Pheochromocytoma: advances in diagnosis and treatment.
Topics: Adrenal Gland Neoplasms; Catecholamines; Child; Creatinine; Diagnosis, Differential; Epinephrine; Fe | 1972 |
1 trial available for normetanephrine and Neuroblastoma
| Article | Year |
|---|---|
[Biochemical measurement of the function of the adrenal medulla and sympathetic system in the clinic].
Topics: Adrenal Medulla; Catecholamines; Clinical Trials as Topic; Depression, Chemical; Epinephrine; Female | 1970 |
24 other studies available for normetanephrine and Neuroblastoma
| Article | Year |
|---|---|
Catecholamines in neuroblastoma: Driver of hypertension, or solely a marker of disease?
Topics: Biomarkers; Catecholamines; Child; Humans; Hypertension; Neuroblastoma; Normetanephrine | 2022 |
Biochemical testing for neuroblastoma using plasma free 3-O-methyldopa, 3-methoxytyramine, and normetanephrine.
Topics: Adolescent; Biomarkers, Tumor; Case-Control Studies; Child; Child, Preschool; Dopamine; Female; Foll | 2020 |
Plasma free metanephrines for diagnosis of neuroblastoma patients.
Topics: Child; Child, Preschool; Chromatography; Cohort Studies; Dopamine; Female; Humans; Infant; Infant, N | 2019 |
[Metanephrine (M), normetanephrine (NM), and fractionated metanephrines].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Child; Child, Preschool; Humans; Infant; Metanephrine; N | 2010 |
Establishment of a paediatric age-related reference interval for the measurement of urinary total fractionated metanephrines.
Topics: Age Factors; Child; Child, Preschool; Chromatography, Reverse-Phase; Epinephrine; Female; Humans; In | 2011 |
Prenatal intrarenal neuroblastoma mimicking a mesoblastic nephroma: a case report.
Topics: Biomarkers, Tumor; Calcinosis; Cesarean Section; Diagnostic Errors; Heart Failure; Humans; Hypertens | 2012 |
Comparative values of catecholamines and metabolites for the diagnosis of neuroblastoma.
Topics: Adrenal Gland Neoplasms; Catecholamines; Chromatography, High Pressure Liquid; Homovanillic Acid; Hu | 2003 |
[NORMAL AND PATHOLOGICAL URINARY ELIMINATION OF THE M-O-METHYLADRENALINE + M-O-METHYLNORADRENALINE MASS].
Topics: Body Fluids; Epinephrine; Metabolism; Neoplasms; Neuroblastoma; Norepinephrine; Normetanephrine; Phe | 1963 |
STUDIES OF FUNCTIONAL NEURAL TUMORS. I. URINARY 3-METHOXY-4-HYDROXY-PHENYL-METABOLITES.
Topics: Adolescent; Alcohols; Amino Acids; Benzoates; Catecholamines; Child; Ganglioneuroma; Humans; Infant; | 1963 |
QUANTITATIVE DETERMINATION OF METANEPHRINE AND NORMETANEPHRINE IN URINE.
Topics: Amines; Chromatography; Dihydroxyphenylalanine; Epinephrine; Fluorescence; Fluorometry; Humans; Indi | 1964 |
Urinary excretion of methylated catecholamine metabolites in a child with neuroblastoma maturing into ganglioneuroma.
Topics: Adrenal Gland Neoplasms; Catecholamines; Dopamine; Ganglioneuroma; Homovanillic Acid; Humans; Infant | 1996 |
Gas-liquid chromatographic and mass fragmentographic determination of 3-O-methylated catecholamines in human plasma.
Topics: Adult; Aged; Catecholamines; Child; Chromatography, Gas; Chromatography, Ion Exchange; Female; Gas C | 1975 |
Methylated catecholamine metabolites for diagnosis of neuroblastoma.
Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Dopamine; Epinephrine; Female; Homovanill | 1992 |
[Clinical significance of metanephrine and normetanephrine analysis in endocrine tests of the adrenal medulla and sympathetic nervous system].
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenal Medulla; Adult; Child; Child, Preschool; Chromatography | 1989 |
N-acetylnormetanephrine and N-acetylmetanephrine in urine from patients with neuroblastoma.
Topics: Catecholamines; Chromatography, Paper; Chromatography, Thin Layer; Humans; Methods; Neuroblastoma; N | 1970 |
[Studies on the secretion of various metabolites of adrenaline and noradrenaline in normotensive and hypertensive patients].
Topics: Catecholamines; Epinephrine; Humans; Hypertension; Mandelic Acids; Neuroblastoma; Norepinephrine; No | 1967 |
[Biochemical diagnosis of pheochromocytoma, neuroblastoma and other neuro-ectodermal neoplasms].
Topics: Adolescent; Adult; Catecholamines; Child; Child, Preschool; Dihydroxyphenylalanine; Dopamine; Electr | 1972 |
Pediatric and adult pheochromocytomas. A biochemical and clinical comparison.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Age Factors; Catecholamines; Child; Child, Preschool; Ep | 1973 |
A metanephrine test for a screening of catecholamine-producing tumors.
Topics: Catecholamines; Epinephrine; Flavoring Agents; Humans; Methods; Methyl Ethers; Neuroblastoma; Normet | 1973 |
A gas-liquid chromatographic method for the separation and quantitation of normetanephrine and metanephrine in human urine.
Topics: Chromatography, Gas; Female; Fluoroacetates; Fluorometry; Humans; Male; Methods; Neuroblastoma; Norm | 1970 |
[Pepper type neuroblastoma with homocystinuria. Diagnosis, biochemistry and therapy].
Topics: Amino Acids; Catecholamines; Child, Preschool; Cyclophosphamide; Dopamine; Homocystinuria; Humans; L | 1970 |
[Catecholamine metabolism in the tissue of malignant and benign tumors of the sympathetic nervous system].
Topics: Catecholamines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Humans; Microscopy, Electron; Neurobl | 1971 |
[Clinical studies on urinary metanephrine and normetanephrine in various endocrine diseases. 2. Clinical studies on urinary metanephrine and normetanephrine in patients with pheochromyocytoma and a patient with neuroblastoma].
Topics: Adult; Bretylium Compounds; Catecholamines; Child, Preschool; Female; Histamine; Humans; Male; Methy | 1968 |
Distribution of metanephrine and normetanephrine in various animals and their analysis in diverse biologic material.
Topics: Animals; Anura; Brain; Cats; Dogs; Epinephrine; Female; Guinea Pigs; Humans; In Vitro Techniques; Ki | 1966 |