Page last updated: 2024-10-26

dichlorvos and Neuroblastoma

dichlorvos has been researched along with Neuroblastoma in 2 studies

Dichlorvos: An organophosphorus insecticide that inhibits ACETYLCHOLINESTERASE.
dichlorvos : An alkenyl phosphate that is the 2,2-dichloroethenyl ester of dimethyl phosphate.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"We have investigated the acute and chronic effect of metrifonate (MTF) and dichlorvos (DDVP), respectively the prodrug and active acetylcholinesterase inhibitor, on the secretory processing of the amyloid precursor protein (APP) in SH-SY5Y neuroblastoma cells."3.71Short- and long-term effect of acetylcholinesterase inhibition on the expression and metabolism of the amyloid precursor protein. ( Caprera, A; Govoni, S; König, G; Racchi, M; Sironi, M, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Schopfer, LM1
Lockridge, O1
Racchi, M1
Sironi, M1
Caprera, A1
König, G1
Govoni, S1

Other Studies

2 other studies available for dichlorvos and Neuroblastoma

ArticleYear
Dichlorvos-induced formation of isopeptide crosslinks between proteins in SH-SY5Y cells.
    Analytical biochemistry, 2022, 10-15, Volume: 655

    Topics: Dichlorvos; Humans; Neuroblastoma; Neurodegenerative Diseases; Organophosphorus Compounds; Peptides;

2022
Short- and long-term effect of acetylcholinesterase inhibition on the expression and metabolism of the amyloid precursor protein.
    Molecular psychiatry, 2001, Volume: 6, Issue:5

    Topics: Acetylcholinesterase; Amyloid beta-Protein Precursor; Atropine; Carbachol; Cholinesterase Inhibitors

2001