Compounds > phenylpyruvic acid
Page last updated: 2024-09-20

phenylpyruvic acid

Description

phenylpyruvic acid: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

phenylpyruvate : A 2-oxo monocarboxylic acid anion resulting from deprotonation of the carboxy group of either keto- or enol-phenylpyruvic acid. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

keto-phenylpyruvic acid : A 2-oxo monocarboxylic acid that is 3-phenylpropanoic acid substituted by an oxo group at position 2. It is an intermediate metabolite in the phenylalanine pathway. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID997
CHEMBL ID1162488
CHEBI ID30851
SCHEMBL ID43235
MeSH IDM0099164

Synonyms (78)

Synonym
2-oxo-3-phenyl-propionic acid
2-oxo-3-phenylpropanoic acid
phenylbrenztraubensaeure
CHEBI:30851 ,
beta-phenylpyruvic acid
keto-phenylpyruvic acid
3-phenyl-2-oxopropanoic acid
alpha-oxo-benzenepropanoic acid
2-oxo-3-phenyl-propanoic acid
pyruvic acid, phenyl-
benzenepropanoic acid, .alpha.-oxo-
PPY ,
C00166
alpha-ketohydrocinnamic acid
phenylpyruvate
3-phenyl-2-oxopropanoate
156-06-9
phenylpyruvic acid
3-phenylpyruvic acid
DB03884
2-oxo-3-phenylpropionic acid
phenylpyruvic acid, 98%
7D5F143E-52E8-4FBB-87F1-0D4F96B4CA60
AC-116009
AKOS000161798
bdbm50167651
alpha-keto-dl-phenylalanine
P0154
b-phenylpyruvic acid
CHEMBL1162488
einecs 205-847-1
benzenepropanoic acid, alpha-oxo-
2-oxo-3-phenylpropanic acid
unii-x7co62m413
x7co62m413 ,
EN300-49247
tox21_301362
dtxcid9022281
NCGC00255726-01
cas-156-06-9
dtxsid1042281 ,
FT-0631855
alpha-keto-phenylalanine
fema no. 3892
2-oxo-3-phenylpropionic acid [fhfi]
.beta.-phenylpyruvic acid
phenylpyruvic acid [who-dd]
3-phenyl-2-oxo propionic acid
phenylpyroracemic acid
.alpha.-oxobenzenepropanoic acid
S6131
phenyl pyruvic acid
phenyl-pyruvic acid
SCHEMBL43235
Q-201562
mfcd00002589
4KIF
phenylpyruvic acid, purum, >=98.0% (t)
phenylpyruvic acid, analytical standard
sr-01000580517
SR-01000580517-1
beta-phenylpyruvate
fema 3892
a-oxobenzenepropanoic acid, 9ci
b-phenylpyruvate
a-hydroxycinnamic acid
alpha-ketohydrocinnamate
2-hydroxy-3-phenyl-2-propenoic acid, 9ci
phenylpyroracemate
HY-W012530
CS-W013246
Q425030
1R-0191
D91915
A883597
STARBLD0007879
SY040637
Z285151774

Research Excerpts

Overview

ExcerptReference
"Phenylpyruvic acid is a deaminated form of phenylalanine and is used in various areas such as development of cheese and wine flavors, diagnosis of phenylketonuria, and to decrease excessive nitrogen accumulation in the manure of farm animals. "( Coban, HB; Demirci, A; Elias, RJ; Patterson, PH, 2016)
"Phenylpyruvic acid (PPA) is an important organic acid that has a wide range of applications. "( Du, G; Hossain, GS; Hou, Y; Li, J; Liu, L; Shin, HD, 2015)

Roles (3)

RoleDescription
fundamental metaboliteAny metabolite produced by all living cells.
chromogenic compoundColourless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into coloured compounds. They are used in biochemical assays and in diagnosis as indicators, particularly in the form of enzyme substrates.
EC 6.4.1.1 (pyruvate carboxylase) inhibitorAn EC 6.4.1.* (carboxylase) inhibitor that interferes with the action of pyruvate carboxylase (EC 6.4.1.1).
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
2-oxo monocarboxylic acidAny monocarboxylic acid having a 2-oxo substituent.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (14)

phenylpyruvic acid is involved in 14 pathway(s), involving a total of 77 unique proteins and 659 unique compounds

PathwayProteinsCompounds
Phenylalanine and Tyrosine Metabolism1121
Phenylketonuria1121
Tyrosinemia Type 2 (or Richner-Hanhart Syndrome)1121
Tyrosinemia Type 3 (TYRO3)1121
Phenylalanine Biosynthesis39
Phenylalanine Metabolism1013
Tropane, Piperidine, and Pyridine Alkaloid Biosynthesis617
Phenylalanine degradation ( Phenylalanine degradation )1314
2-Oxo-glutaric acid + L-Phenylalanine = L-Glutamic acid + Phenyl-pyruvic acid ( Phenylalanine degradation )14
Phenylalanine, tyrosine, and tryptophan biosynthesis012
phenylalanine biosynthesis06
Phenylalanine biosynthesis08
Tryptophan degradation07
Biochemical pathways: part I0466
Phenylalanine biosynthesis I08
Ehrlich pathway011

Protein Targets (10)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
GLI family zinc finger 3Homo sapiens (human)Potency47.94780.000714.592883.7951AID1259369; AID1259392
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency56.78100.001022.650876.6163AID1224838; AID1224893
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency10.96220.000214.376460.0339AID720691
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency68.58960.003041.611522,387.1992AID1159552; AID1159555
thyroid stimulating hormone receptorHomo sapiens (human)Potency28.45790.001628.015177.1139AID1224843; AID1224895
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency58.19650.057821.109761.2679AID1159528
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency27.30600.000627.21521,122.0200AID743202; AID743219
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Solute carrier family 22 member 20Mus musculus (house mouse)Ki28.92011.10006.67899.1201AID360149
Solute carrier family 22 member 6Mus musculus (house mouse)Ki79.14430.40745.02179.4000AID360150; AID598880
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (8)

Processvia Protein(s)Taxonomy
positive regulation of transcription by RNA polymerase IIC-terminal-binding protein 2Homo sapiens (human)
positive regulation of retinoic acid receptor signaling pathwayC-terminal-binding protein 2Homo sapiens (human)
negative regulation of transcription by RNA polymerase IIC-terminal-binding protein 2Homo sapiens (human)
negative regulation of cell population proliferationC-terminal-binding protein 2Homo sapiens (human)
viral genome replicationC-terminal-binding protein 2Homo sapiens (human)
negative regulation of DNA-templated transcriptionC-terminal-binding protein 2Homo sapiens (human)
white fat cell differentiationC-terminal-binding protein 2Homo sapiens (human)
regulation of transcription by RNA polymerase IIC-terminal-binding protein 2Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (10)

Processvia Protein(s)Taxonomy
transcription corepressor bindingC-terminal-binding protein 2Homo sapiens (human)
transcription corepressor activityC-terminal-binding protein 2Homo sapiens (human)
protein bindingC-terminal-binding protein 2Homo sapiens (human)
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorC-terminal-binding protein 2Homo sapiens (human)
protein kinase bindingC-terminal-binding protein 2Homo sapiens (human)
protein-containing complex bindingC-terminal-binding protein 2Homo sapiens (human)
NAD bindingC-terminal-binding protein 2Homo sapiens (human)
DNA-binding transcription factor bindingC-terminal-binding protein 2Homo sapiens (human)
transcription coregulator bindingC-terminal-binding protein 2Homo sapiens (human)
transcription coactivator activityC-terminal-binding protein 2Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (3)

Processvia Protein(s)Taxonomy
nucleusC-terminal-binding protein 2Homo sapiens (human)
synapseC-terminal-binding protein 2Homo sapiens (human)
transcription repressor complexC-terminal-binding protein 2Homo sapiens (human)
nucleusC-terminal-binding protein 2Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (9)

Assay IDTitleYearJournalArticle
AID977611Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB2014Acta crystallographica. Section D, Biological crystallography, Jun, Volume: 70, Issue:Pt 6
Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase.
AID360150Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr2007The Journal of biological chemistry, Aug-17, Volume: 282, Issue:33
Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.
AID1453183Binding affinity to CK2alpha (unknown origin) assessed as change in melting temperature by thermal shift assay2017Bioorganic & medicinal chemistry, 07-01, Volume: 25, Issue:13
A fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066.
AID681140TP_TRANSPORTER: uptake in Xenopus laevis oocytes2000The Journal of physiology, Dec-01, Volume: 529 Pt 2Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle.
AID1130306Inhibition of glycolic acid oxidase (unknown origin) assessed as enzyme-mediated reduction of NaDCIP by sodium glycolate after 1 to 3 mins by spectrophotometer analysis1979Journal of medicinal chemistry, Jun, Volume: 22, Issue:6
Quantitative structure-activity relationships involving the inhibition of glycolic acid oxidase by derivatives of glycolic and glyoxylic acids.
AID360151Ratio of pKi for mouse Oat1 expressed in Xenopus oocytes to pKi for mouse Oat6 expressed in Xenopus oocytes2007The Journal of biological chemistry, Aug-17, Volume: 282, Issue:33
Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.
AID1298930Inhibition of recombinant His6-tagged CtBP2 (31 to 384 residues) (unknown origin) dehydrogenase activity expressed in Escherichia coli BL21-Codonplus (DE3)-RIL cells using MTOB as substrate after 15 mins by NADH consumption assay2016Bioorganic & medicinal chemistry, 06-15, Volume: 24, Issue:12
Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP).
AID360149Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr2007The Journal of biological chemistry, Aug-17, Volume: 282, Issue:33
Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.
AID598880Inhibition of mouse Oat1 expressed in Xenopus oocytes2011Bioorganic & medicinal chemistry, Jun-01, Volume: 19, Issue:11
Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter-Organic anion transporter1 (Oat1).
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (297)

TimeframeStudies, This Drug (%)All Drugs %
pre-1990153 (51.52)18.7374
1990's34 (11.45)18.2507
2000's37 (12.46)29.6817
2010's55 (18.52)24.3611
2020's18 (6.06)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (0.32%)5.53%
Reviews6 (1.93%)6.00%
Case Studies2 (0.64%)4.05%
Observational0 (0.00%)0.25%
Other302 (97.11%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
mandelic acid[no description available]medium602-hydroxy monocarboxylic acid;
benzenes		antibacterial agent;
human xenobiotic metabolite
3-phenyllactic acid[no description available]medium1802-hydroxy monocarboxylic acidhuman metabolite
2-naphthoxyacetic acid[no description available]medium10naphthyloxyacetic acid
alpha-hydroxy-gamma-methylmercaptobutyric acid[no description available]medium10thia fatty acid
phenylglyoxylic acid[no description available]medium502-oxo monocarboxylic acidbiomarker;
human xenobiotic metabolite
(4-tert-Butyl-phenoxy)-acetic acid[no description available]medium10monocarboxylic acid
4-hydroxyphenoxyacetic acid[no description available]medium10monocarboxylic acid
guaiacoxyacetic acid[no description available]medium10
phenoxyacetic acid[no description available]medium10aromatic ether;
monocarboxylic acid		allergen;
Aspergillus metabolite;
human xenobiotic metabolite;
plant growth retardant
4-chlorophenoxyacetic acid[no description available]medium10chlorophenoxyacetic acid;
monochlorobenzenes		phenoxy herbicide
alpha-hydroxyisocaproic acid[no description available]medium202-hydroxy fatty acid;
branched-chain fatty acid		metabolite
salicylamide-2-acetic acid[no description available]medium10monocarboxylic acid
2-chloromandelic acid[no description available]medium10
4-fluoro-alpha-hydroxybenzeneacetic acid[no description available]medium10
alpha-ketocaproic acid[no description available]medium302-oxo monocarboxylic acid;
medium-chain fatty acid;
oxo fatty acid;
straight-chain fatty acid		human blood serum metabolite
alpha-ketoisovalerate[no description available]medium402-oxo monocarboxylic acid;
branched-chain keto acid		human metabolite;
Saccharomyces cerevisiae metabolite
alpha-ketobutyric acid[no description available]medium702-oxo monocarboxylic acid;
short-chain fatty acid
2-keto-4-methylvalerate[no description available]medium902-oxo monocarboxylic acid;
branched-chain keto acid		algal metabolite;
human metabolite
acetoacetic acid[no description available]medium103-oxo fatty acid;
ketone body		metabolite
glyoxylic acid[no description available]medium302-oxo monocarboxylic acid;
aldehydic acid		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
carbonic acid[no description available]medium10carbon oxoacid;
chalcocarbonic acid		mouse metabolite
oxamic acid[no description available]medium10dicarboxylic acid monoamideEscherichia coli metabolite
pyruvic acid[no description available]high1902-oxo monocarboxylic acidcofactor;
fundamental metabolite
1-methyl-3-isobutylxanthine[no description available]medium103-isobutyl-1-methylxanthine
5-nitro-2-(3-phenylpropylamino)benzoic acid[no description available]medium10nitrobenzoic acid
phloretin[no description available]medium20dihydrochalconesantineoplastic agent;
plant metabolite
3-chloropropionic acid[no description available]medium10
4-hydroxybutyric acid[no description available]medium104-hydroxy monocarboxylic acid;
hydroxybutyric acid		general anaesthetic;
GHB receptor agonist;
neurotoxin;
sedative
2-hydroxybutyric acid[no description available]medium102-hydroxy monocarboxylic acid;
hydroxybutyric acid		algal metabolite;
human metabolite
d-lactic acid[no description available]medium102-hydroxypropanoic acidEscherichia coli metabolite;
human metabolite
3-hydroxybutyric acid[no description available]medium203-hydroxybutyric acid;
ketone body		fungal metabolite;
human metabolite;
pheromone
(S)-3-hydroxybutyric acid[no description available]medium303-hydroxybutyric acid
formic acid, sodium salt[no description available]medium10organic sodium saltastringent;
buffer
alpha-cyano-4-hydroxycinnamic acid[no description available]medium10monohydroxycinnamic acid;
nitrile;
phenols		MALDI matrix material
sodium lactate[no description available]medium10lactate salt;
organic sodium salt		food acidity regulator;
food preservative
adipic acid[no description available]medium10alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		food acidity regulator;
human xenobiotic metabolite
benzoic acid[no description available]medium10benzoic acidsalgal metabolite;
antimicrobial food preservative;
drug allergen;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
human xenobiotic metabolite;
plant metabolite
butyric acid[no description available]medium10fatty acid 4:0;
straight-chain saturated fatty acid		human urinary metabolite;
Mycoplasma genitalium metabolite
salicylic acid[no description available]medium20monohydroxybenzoic acidalgal metabolite;
antifungal agent;
antiinfective agent;
EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor;
keratolytic drug;
plant hormone;
plant metabolite
3-hydroxybutyric acid[no description available]medium10(omega-1)-hydroxy fatty acid;
3-hydroxy monocarboxylic acid;
hydroxybutyric acid		human metabolite
hippuric acid[no description available]medium20N-acylglycinehuman blood serum metabolite;
uremic toxin
glutaric acid[no description available]medium10alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		Daphnia magna metabolite;
human metabolite
4-hydroxyphenylpyruvic acid[no description available]medium1402-oxo monocarboxylic acid;
phenols		human metabolite
propionic acid[no description available]medium10saturated fatty acid;
short-chain fatty acid		antifungal drug
p-aminohippuric acid[no description available]medium20N-acylglycineDaphnia magna metabolite
aspirin[no description available]medium10benzoic acids;
phenyl acetates;
salicylates		anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent
fluorescite[no description available]medium10benzoic acids;
cyclic ketone;
hydroxy monocarboxylic acid;
organic heterotricyclic compound;
phenols;
xanthene dye		fluorescent dye;
radioopaque medium
ibuprofen[no description available]medium10monocarboxylic acidantipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
radical scavenger;
xenobiotic
probenecid[no description available]medium10benzoic acids;
sulfonamide		uricosuric drug
heptanoic acid[no description available]medium10medium-chain fatty acid;
straight-chain saturated fatty acid		plant metabolite
2-methylbutanoic acid[no description available]medium10methylbutyric acidbacterial metabolite;
human metabolite
2-ethylhexanoic acid[no description available]medium10branched-chain fatty acid
hexanoic acid[no description available]medium10medium-chain fatty acid;
straight-chain saturated fatty acid		human metabolite;
plant metabolite
4-hydroxyphenyllactic acid[no description available]medium302-hydroxy carboxylic acid;
phenols		bacterial metabolite;
human metabolite
isovaleric acid[no description available]medium10branched-chain saturated fatty acid;
methylbutyric acid;
short-chain fatty acid		mammalian metabolite;
plant metabolite
suberic acid[no description available]medium10alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		human metabolite
carbenicillin disodium[no description available]medium10organic sodium salt
ticarcillin[no description available]medium10penicillin allergen;
penicillin		antibacterial drug
n-acetylaspartic acid[no description available]medium20N-acetyl-L-amino acid;
N-acyl-L-aspartic acid		antioxidant;
human metabolite;
mouse metabolite;
nutraceutical;
rat metabolite
estradiol 3,17-disulfate[no description available]medium10steroid sulfate
N-Acetyl-DL-aspartic acid[no description available]medium10aspartic acid derivative
2-hydroxyisovaleric acid[no description available]medium102-hydroxy monocarboxylic acidhuman metabolite
methotrexate[no description available]medium10dicarboxylic acid;
monocarboxylic acid amide;
pteridines		abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent
ochratoxin a[no description available]medium10isochromanes;
monocarboxylic acid amide;
N-acyl-L-phenylalanine;
organochlorine compound;
phenylalanine derivative		Aspergillus metabolite;
calcium channel blocker;
carcinogenic agent;
mycotoxin;
nephrotoxin;
Penicillium metabolite;
teratogenic agent
fumaric acid[no description available]medium10butenedioic acidfood acidity regulator;
fundamental metabolite;
geroprotector
estrone sulfate[no description available]medium1017-oxo steroid;
steroid sulfate		human metabolite;
mouse metabolite
dinoprostone[no description available]medium10prostaglandins Ehuman metabolite;
mouse metabolite;
oxytocic
penicillin g sodium[no description available]medium10organic sodium salt
chlorpropamide[no description available]medium10monochlorobenzenes;
N-sulfonylurea		hypoglycemic agent;
insulin secretagogue
etodolac[no description available]medium10monocarboxylic acid;
organic heterotricyclic compound		antipyretic;
cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
tolbutamide[no description available]medium10N-sulfonylureahuman metabolite;
hypoglycemic agent;
insulin secretagogue;
potassium channel blocker
salicylurate[no description available]medium10N-acylglycine;
secondary carboxamide		human xenobiotic metabolite;
uremic toxin
pravastatin[no description available]medium103-hydroxy carboxylic acid;
carbobicyclic compound;
carboxylic ester;
hydroxy monocarboxylic acid;
secondary alcohol;
statin (semi-synthetic)		anticholesteremic drug;
environmental contaminant;
metabolite;
xenobiotic
betamipron[no description available]medium10organonitrogen compound;
organooxygen compound
3-hydroxyglutaric acid[no description available]medium103-hydroxy carboxylic acid;
alpha,omega-dicarboxylic acid		human blood serum metabolite;
human urinary metabolite
alpha-hydroxyglutarate, (l)-isomer[no description available]medium102-hydroxyglutaric acid
estradiol-17 beta-glucuronide[no description available]medium103-hydroxy steroid;
steroid glucosiduronic acid
nateglinide[no description available]medium10phenylalanine derivative
citrinin[no description available]medium10
3-phenylpropionic acid[no description available]medium10benzenes;
monocarboxylic acid		antifungal agent;
human metabolite;
plant metabolite
2-keto-4-methylthiobutyric acid[no description available]medium20omega-(methylthio)-2-oxocarboxylic acid
1-phenyl-2-propanone[no description available]medium10methyl ketone;
propanones
oxanilic acid[no description available]medium10
2-benzylmalonate[no description available]medium10
protocatechuic acid[no description available]medium10catechols;
dihydroxybenzoic acid		antineoplastic agent;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor;
human xenobiotic metabolite;
plant metabolite
beta-resorcylic acid[no description available]medium10
homovanillic acid[no description available]medium10guaiacols;
monocarboxylic acid		human metabolite;
mouse metabolite
5-fluoroindole-2-carboxylic acid[no description available]medium10indolyl carboxylic acid
chromone-2-carboxylic acid[no description available]medium10chromones
5-methylsalicylic acid[no description available]medium10
quinaldic acid[no description available]medium10quinolinemonocarboxylic acidhuman metabolite;
Saccharomyces cerevisiae metabolite
3-aminobenzoic acid[no description available]medium10aminobenzoic acid
dipicolinic acid[no description available]medium10pyridinedicarboxylic acidbacterial metabolite
phloretic acid[no description available]medium10hydroxy monocarboxylic acidplant metabolite
4-hydrazinobenzoic acid[no description available]medium10
4-hydroxybenzamide[no description available]medium10
2-hydroxynicotinic acid[no description available]medium10aromatic carboxylic acid;
pyridines
4-hydroxycoumarin[no description available]medium10hydroxycoumarin
phenylalanine[no description available]medium910amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
phenylalanine;
proteinogenic amino acid		algal metabolite;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
Escherichia coli metabolite;
human xenobiotic metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
virginiamycin[no description available]medium11
phenylacetylglutamine[no description available]medium10N(2)-phenylacetylglutaminehuman metabolite
glutamine[no description available]medium40amino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
tyrosine[no description available]medium440amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine		EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
deuterium[no description available]medium10dihydrogen
hydrogen[no description available]medium10elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
isovalerylaldehyde[no description available]medium10methylbutanalflavouring agent;
plant metabolite;
Saccharomyces cerevisiae metabolite;
volatile oil component
phenylacetaldehyde[no description available]medium30alpha-CH2-containing aldehyde;
phenylacetaldehydes		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
glucose, (beta-d)-isomer[no description available]medium20D-glucopyranoseepitope;
mouse metabolite
orientin[no description available]medium103'-hydroxyflavonoid;
C-glycosyl compound;
tetrahydroxyflavone		antioxidant;
metabolite
aspalathin[no description available]medium20C-glycosyl compound;
catechols;
dihydrochalcones;
polyketide;
polyphenol		antioxidant;
EC 1.17.3.2 (xanthine oxidase) inhibitor;
hypoglycemic agent;
plant metabolite
indol-3-yl pyruvic acid[no description available]medium302-oxo monocarboxylic acid;
indol-3-yl carboxylic acid		plant metabolite;
Saccharomyces cerevisiae metabolite
indoleacetic acid[no description available]medium60indole-3-acetic acids;
monocarboxylic acid		auxin;
human metabolite;
mouse metabolite;
plant hormone;
plant metabolite
tryptophan[no description available]medium110erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
metformin[no description available]medium10guanidinesenvironmental contaminant;
geroprotector;
hypoglycemic agent;
xenobiotic
caseins[no description available]medium10
linoleic acid[no description available]medium10octadecadienoic acid;
omega-6 fatty acid		algal metabolite;
Daphnia galeata metabolite;
plant metabolite
sucrose[no description available]medium10glycosyl glycosidealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent
lactic acid[no description available]medium1102-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
lincomycin[no description available]medium10carbohydrate-containing antibiotic;
L-proline derivative;
monocarboxylic acid amide;
pyrrolidinecarboxamide;
S-glycosyl compound		antimicrobial agent;
bacterial metabolite
proline[no description available]medium20amino acid zwitterion;
glutamine family amino acid;
L-alpha-amino acid;
proline;
proteinogenic amino acid		algal metabolite;
compatible osmolytes;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
anthramycin[no description available]medium10
prephenic acid[no description available]medium50oxo dicarboxylic acidEscherichia coli metabolite;
plant metabolite
pretyrosine[no description available]medium30dicarboxylic acid anion
benzaldehyde[no description available]medium50benzaldehydesEC 3.1.1.3 (triacylglycerol lipase) inhibitor;
EC 3.5.5.1 (nitrilase) inhibitor;
flavouring agent;
fragrance;
odorant receptor agonist;
plant metabolite
phenylethyl alcohol[no description available]medium20benzenes;
primary alcohol		Aspergillus metabolite;
fragrance;
plant growth retardant;
plant metabolite;
Saccharomyces cerevisiae metabolite
aspartic acid[no description available]medium20aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
oxaloacetic acid[no description available]medium20C4-dicarboxylic acid;
oxo dicarboxylic acid		geroprotector;
metabolite
glutamic acid[no description available]medium70glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical
nadp[no description available]medium30
2-amino-4-phenylbutyric acid[no description available]medium10
nad[no description available]medium100organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
hydroxypyruvic acid[no description available]medium302-oxo monocarboxylic acid;
3-hydroxy monocarboxylic acid;
primary alpha-hydroxy ketone		Escherichia coli metabolite;
human metabolite
acyloin[no description available]medium10
chorismic acid[no description available]medium205-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acidEscherichia coli metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
valine[no description available]medium60L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid;
valine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
formaldehyde[no description available]medium10aldehyde;
one-carbon compound		allergen;
carcinogenic agent;
disinfectant;
EC 3.5.1.4 (amidase) inhibitor;
environmental contaminant;
Escherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
acetaldehyde[no description available]medium40aldehydecarcinogenic agent;
EC 3.5.1.4 (amidase) inhibitor;
electron acceptor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
mutagen;
oxidising agent;
Saccharomyces cerevisiae metabolite;
teratogenic agent
greigite[no description available]medium10iron(2+) sulfides;
iron(3+) sulfides;
sulfide mineral		catalyst
formic acid[no description available]medium10monocarboxylic acidantibacterial agent;
astringent;
metabolite;
protic solvent;
solvent
cycloheximide[no description available]medium10antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol		anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor
alpha-cyano-4-hydroxycinnamate[no description available]medium60
cysteine[no description available]medium20cysteiniumfundamental metabolite
acetylglucosamine[no description available]medium10N-acetyl-D-glucosamineepitope
kynurenine[no description available]medium20aromatic ketone;
non-proteinogenic alpha-amino acid;
substituted aniline		human metabolite
4-hydroxyphenylacetic acid[no description available]medium20monocarboxylic acid;
phenols		fungal metabolite;
human metabolite;
mouse metabolite;
plant metabolite
sodium dodecyl sulfate[no description available]medium10organic sodium saltdetergent;
protein denaturant
2-hydroxyphenylacetic acid[no description available]medium30hydroxy monocarboxylic acid;
phenols		human metabolite;
mouse metabolite
uric acid[no description available]medium10uric acidEscherichia coli metabolite;
human metabolite;
mouse metabolite
phenylacetic acid[no description available]medium130benzenes;
monocarboxylic acid;
phenylacetic acids		allergen;
Aspergillus metabolite;
auxin;
EC 6.4.1.1 (pyruvate carboxylase) inhibitor;
Escherichia coli metabolite;
human metabolite;
plant growth retardant;
plant metabolite;
Saccharomyces cerevisiae metabolite;
toxin
maltol[no description available]medium104-pyranonesmetabolite
histidine[no description available]medium10amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
penicillin g[no description available]medium10penicillin allergen;
penicillin		antibacterial drug;
drug allergen;
epitope
ferene-s[no description available]medium10
adenosine diphosphate[no description available]medium30adenosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite;
human metabolite
alanine[no description available]medium60alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid		EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite
phosphoenolpyruvate[no description available]medium10carboxyalkyl phosphate;
monocarboxylic acid		fundamental metabolite
apyrase[no description available]medium20
thiamine pyrophosphate[no description available]medium20organic chloride salt;
vitamin B1
phenyl acetate[no description available]medium50benzenes;
phenyl acetates
homogentisic acid[no description available]medium30dihydroxyphenylacetic acid;
hydroquinones		human metabolite;
plant metabolite
hydrazine[no description available]medium10azane;
hydrazines		EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
phenylhydrazine[no description available]medium10phenylhydrazinesxenobiotic
D-fructopyranose[no description available]medium20cyclic hemiketal;
D-fructose;
fructopyranose		sweetening agent
lignin[no description available]medium20
3,4-dihydroxyphenylpyruvic acid[no description available]medium102-oxo monocarboxylic acidmetabolite
4-hydroxybenzaldehyde[no description available]medium10hydroxybenzaldehydeEC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor;
mouse metabolite;
plant metabolite
ascorbic acid[no description available]medium60ascorbic acid;
vitamin C		coenzyme;
cofactor;
flour treatment agent;
food antioxidant;
food colour retention agent;
geroprotector;
plant metabolite;
skin lightening agent
indophenol[no description available]medium30quinone iminedye
diiodotyrosine[no description available]medium30diiodotyrosine;
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		human metabolite;
mouse metabolite
thyroxine[no description available]medium502-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine zwitterion;
thyroxine		antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone
oxalates[no description available]medium20
adenosine monophosphate[no description available]medium10adenosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate		adenosine A1 receptor agonist;
cofactor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.11 (fructose-bisphosphatase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
tyramine[no description available]medium10monoamine molecular messenger;
primary amino compound;
tyramines		EC 3.1.1.8 (cholinesterase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter
thyronines[no description available]medium10thyronine
leucine[no description available]medium80amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
methotrimeprazine[no description available]medium20phenothiazines;
tertiary amine		anticoronaviral agent;
cholinergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
non-narcotic analgesic;
phenothiazine antipsychotic drug;
serotonergic antagonist
iproniazid[no description available]medium10carbohydrazide;
pyridines
pyridoxine[no description available]medium20hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine;
vitamin B6		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
shikimic acid[no description available]medium30alpha,beta-unsaturated monocarboxylic acid;
cyclohexenecarboxylic acid;
hydroxy monocarboxylic acid		Escherichia coli metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
anthranilic acid[no description available]medium10aminobenzoic acidhuman metabolite;
mouse metabolite
glycine[no description available]medium10alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
triiodothyronine[no description available]medium302-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine		human metabolite;
mouse metabolite;
thyroid hormone
pyridoxal phosphate[no description available]medium10methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6 phosphate		coenzyme;
cofactor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
nialamide[no description available]medium10organonitrogen compound;
organooxygen compound
asparagine[no description available]medium10amino acid zwitterion;
asparagine;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
skatole[no description available]medium10methylindolehuman metabolite;
mammalian metabolite
chlorine[no description available]medium20halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
dihydroxyphenylalanine[no description available]medium30hydroxyphenylalanine;
non-proteinogenic alpha-amino acid;
tyrosine derivative		human metabolite
5-hydroxytryptophan[no description available]medium10hydroxytryptophanhuman metabolite;
neurotransmitter
reserpine[no description available]medium10alkaloid ester;
methyl ester;
yohimban alkaloid		adrenergic uptake inhibitor;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
first generation antipsychotic;
plant metabolite;
xenobiotic
chlorpromazine[no description available]medium10organochlorine compound;
phenothiazines;
tertiary amine		anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
phenothiazine antipsychotic drug
e-z cinnamic acid[no description available]medium10cinnamic acidplant metabolite
barium[no description available]medium10alkaline earth metal atom;
elemental barium
peptones[no description available]medium10
arsenic[no description available]medium10metalloid atom;
pnictogen		micronutrient
pyrroles[no description available]medium10pyrrole;
secondary amine
tin[no description available]medium10carbon group element atom;
elemental tin;
metal atom		micronutrient
nickel[no description available]medium10metal allergen;
nickel group element atom		epitope;
micronutrient
mercury[no description available]medium10elemental mercury;
zinc group element atom		neurotoxin
chromates[no description available]medium10chromium oxoanion;
divalent inorganic anion		oxidising agent
1,7-phenanthroline[no description available]medium10phenanthroline
diethylstilbestrol[no description available]medium10olefinic compound;
polyphenol		antifungal agent;
antineoplastic agent;
autophagy inducer;
calcium channel blocker;
carcinogenic agent;
EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
endocrine disruptor;
xenoestrogen
isoniazid[no description available]medium10carbohydrazideantitubercular agent;
drug allergen
copper gluconate[no description available]medium10organic molecular entity
levomepromazine maleate[no description available]medium10
arginine[no description available]medium30arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
trypsinogen[no description available]medium10
triiodothyronine, reverse[no description available]medium103,3',5'-triiodothyronine;
amino acid zwitterion
methionine[no description available]medium20aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
urea[no description available]medium30isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
threonine[no description available]medium20amino acid zwitterion;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
threonine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
tyrosine o-sulfate[no description available]medium10aryl sulfate;
L-tyrosine derivative;
O-sulfoamino acid		human metabolite
galactose[no description available]medium10D-galactose;
galactopyranose		Escherichia coli metabolite;
mouse metabolite
luteolin[no description available]medium103'-hydroxyflavonoid;
tetrahydroxyflavone		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
c-Jun N-terminal kinase inhibitor;
EC 2.3.1.85 (fatty acid synthase) inhibitor;
immunomodulator;
nephroprotective agent;
plant metabolite;
radical scavenger;
vascular endothelial growth factor receptor antagonist
quercetin[no description available]medium107-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger
methacrylic acid[no description available]medium10alpha,beta-unsaturated monocarboxylic acid
ethylene dimethacrylate[no description available]medium10enoate esterallergen;
cross-linking reagent;
polymerisation monomer
pyridoxal[no description available]medium10hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
pyridoxamine[no description available]medium20aminoalkylpyridine;
hydroxymethylpyridine;
monohydroxypyridine;
vitamin B6		Escherichia coli metabolite;
human metabolite;
iron chelator;
mouse metabolite;
nephroprotective agent;
plant metabolite;
Saccharomyces cerevisiae metabolite
caffeic acid[no description available]medium10caffeic acidgeroprotector;
mouse metabolite
resveratrol[no description available]medium10resveratrolantioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger
curcumin[no description available]medium10aromatic ether;
beta-diketone;
diarylheptanoid;
enone;
polyphenol		anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
biological pigment;
contraceptive drug;
dye;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
flavouring agent;
food colouring;
geroprotector;
hepatoprotective agent;
immunomodulator;
iron chelator;
ligand;
lipoxygenase inhibitor;
metabolite;
neuroprotective agent;
nutraceutical;
radical scavenger
stilbenes[no description available]medium10stilbene
4-phenylbutyric acid[no description available]medium10monocarboxylic acidantineoplastic agent;
apoptosis inducer;
EC 3.5.1.98 (histone deacetylase) inhibitor;
prodrug
phenethylamine[no description available]medium20alkaloid;
aralkylamine;
phenylethylamine		Escherichia coli metabolite;
human metabolite;
mouse metabolite
2-oxo-3-methylvalerate[no description available]medium202-oxo monocarboxylic acid;
branched-chain keto acid		human metabolite
nitrogen dioxide[no description available]medium10nitrogen oxide
4,5-epoxy-2-decenal[no description available]medium10enal
acetonitrile[no description available]medium10aliphatic nitrile;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
NMR chemical shift reference compound;
polar aprotic solvent
3-chloroacrylic acid[no description available]medium10
violacein[no description available]medium10
acrolein[no description available]medium10enalherbicide;
human xenobiotic metabolite;
toxin
benzoin[no description available]medium10benzoins;
secondary alpha-hydroxy ketone		EC 3.1.1.1 (carboxylesterase) inhibitor
rubidium[no description available]medium10alkali metal atom
norleucine[no description available]medium202-aminohexanoic acid;
L-alpha-amino acid zwitterion;
non-proteinogenic L-alpha-amino acid
galactose[no description available]medium10
aminooxyacetic acid[no description available]medium30amino acid;
hydroxylamines;
monocarboxylic acid		anticonvulsant;
EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor;
EC 4.2.1.22 (cystathionine beta-synthase) inhibitor;
nootropic agent
ammonium hydroxide[no description available]medium40azane;
gas molecular entity;
mononuclear parent hydride		EC 3.5.1.4 (amidase) inhibitor;
metabolite;
mouse metabolite;
neurotoxin;
NMR chemical shift reference compound;
nucleophilic reagent;
refrigerant
dichloroacetic acid[no description available]medium10monocarboxylic acid;
organochlorine compound		astringent;
marine metabolite
clofibric acid[no description available]medium10aromatic ether;
monocarboxylic acid;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
antineoplastic agent;
herbicide;
marine xenobiotic metabolite;
PPARalpha agonist
clofibrate[no description available]medium10aromatic ether;
ethyl ester;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
geroprotector;
PPARalpha agonist
2-n-butylmalonate[no description available]medium10
2-phenylsuccinate[no description available]medium10
2-aminobicyclo(2,2,1)heptane-2-carboxylic acid[no description available]medium30monoterpenoid
fluorescein[no description available]medium302-benzofurans;
gamma-lactone;
organic heteropentacyclic compound;
oxaspiro compound;
polyphenol;
xanthene dye		fluorescent dye;
radioopaque medium
malic acid[no description available]medium302-hydroxydicarboxylic acid;
C4-dicarboxylic acid		food acidity regulator;
fundamental metabolite
ouabain[no description available]medium1011alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone		anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite
cadmium[no description available]medium20cadmium molecular entity;
zinc group element atom
nystatin a1[no description available]medium10nystatins
malonic acid[no description available]medium20alpha,omega-dicarboxylic acidhuman metabolite
methylphenazonium methosulfate[no description available]medium10azaheterocycle sulfate salt;
phenazines
erythrosine[no description available]medium40
cyanamide[no description available]medium10nitrile;
one-carbon compound		EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor
pyrazole[no description available]medium10pyrazole
quinolinic acid[no description available]medium10pyridinedicarboxylic acidEscherichia coli metabolite;
human metabolite;
mouse metabolite;
NMDA receptor agonist
2-ketopentanoic acid[no description available]medium102-oxo monocarboxylic acid;
oxopentanoic acid		human metabolite
isocaproic acid[no description available]medium10branched-chain saturated fatty acid;
medium-chain fatty acid;
methyl-branched fatty acid		human metabolite
palmitic acid[no description available]medium10long-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
Daphnia magna metabolite;
EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor;
plant metabolite
glycerol[no description available]medium10alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
2-propyl-4-pentenoic acid[no description available]medium10methyl-branched fatty acid
maleic acid[no description available]medium10butenedioic acidalgal metabolite;
mouse metabolite;
plant metabolite
dopachrome[no description available]medium10orthoquinones
5,6-dihydroxy-2-indolylcarboxylic acid[no description available]medium10dihydroxyindolemouse metabolite
suramin[no description available]medium10naphthalenesulfonic acid;
phenylureas;
secondary carboxamide		angiogenesis inhibitor;
antinematodal drug;
antineoplastic agent;
apoptosis inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
GABA antagonist;
GABA-gated chloride channel antagonist;
purinergic receptor P2 antagonist;
ryanodine receptor agonist;
trypanocidal drug
carbonyl cyanide p-trifluoromethoxyphenylhydrazone[no description available]medium10aromatic ether;
hydrazone;
nitrile;
organofluorine compound		ATP synthase inhibitor;
geroprotector;
ionophore
valinomycin[no description available]medium10cyclodepsipeptide;
macrocycle		antimicrobial agent;
antiviral agent;
bacterial metabolite;
potassium ionophore
monensin[no description available]medium10cyclic hemiketal;
monocarboxylic acid;
polyether antibiotic;
spiroketal		antifungal agent;
coccidiostat;
ionophore
rotenone[no description available]medium10organic heteropentacyclic compound;
rotenones		antineoplastic agent;
metabolite;
mitochondrial NADH:ubiquinone reductase inhibitor;
phytogenic insecticide;
piscicide;
toxin
guanosine diphosphate[no description available]medium10guanosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		Escherichia coli metabolite;
mouse metabolite;
uncoupling protein inhibitor
manganese[no description available]medium20elemental manganese;
manganese group element atom		Escherichia coli metabolite;
micronutrient
isoleucine[no description available]medium10aspartate family amino acid;
isoleucine;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
sodium azide[no description available]medium10inorganic sodium saltantibacterial agent;
explosive;
mitochondrial respiratory-chain inhibitor;
mutagen
sodium cyanide[no description available]medium10cyanide salt;
one-carbon compound;
sodium salt		EC 1.15.1.1 (superoxide dismutase) inhibitor
diazoxide[no description available]medium10benzothiadiazine;
organochlorine compound;
sulfone		antihypertensive agent;
beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
diuretic;
K-ATP channel agonist;
sodium channel blocker;
sympathomimetic agent;
vasodilator agent
verapamil[no description available]medium10aromatic ether;
nitrile;
polyether;
tertiary amino compound
sodium hypochlorite[no description available]medium10inorganic sodium saltbleaching agent;
disinfectant
carnitine[no description available]medium10amino-acid betainehuman metabolite;
mouse metabolite
betaine[no description available]medium10amino-acid betaine;
glycine derivative		fundamental metabolite
gamma-butyrobetaine[no description available]medium10amino-acid betaineEscherichia coli metabolite;
human metabolite
s-adenosylmethionine[no description available]medium10sulfonium betainehuman metabolite
adenosine[no description available]medium10adenosines;
purines D-ribonucleoside		analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent
dapsone[no description available]medium10substituted aniline;
sulfone		anti-inflammatory drug;
antiinfective agent;
antimalarial;
leprostatic drug
sulfoxone[no description available]medium10sulfonamide
fructose-1,6-diphosphate[no description available]medium10
methanesulfinic acid[no description available]medium10organosulfinic acid
3-mercaptopyruvic acid[no description available]medium102-oxo monocarboxylic acid;
thiol		antidote to cyanide poisoning;
Escherichia coli metabolite;
human metabolite;
mouse metabolite
taurine[no description available]medium10amino sulfonic acid;
zwitterion		antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite
hypotaurine[no description available]medium10aminosulfinic acid;
zwitterion		human metabolite;
metabolite;
mouse metabolite
cyanides[no description available]medium10pseudohalide anionEC 1.9.3.1 (cytochrome c oxidase) inhibitor
atrolactic acid[no description available]medium102-hydroxy monocarboxylic acid
mevalonic acid[no description available]medium203,5-dihydroxy-3-methylpentanoic acid
cobalt[no description available]medium10cobalt group element atom;
metal allergen		micronutrient
dimethyldioctadecylammonium[no description available]medium10
glutaminase[no description available]medium10
alpha-cyanocinnamate[no description available]medium10
oxalic acid[no description available]medium10alpha,omega-dicarboxylic acidalgal metabolite;
human metabolite;
plant metabolite
arphamenine a[no description available]medium10
benzylsuccinic acid[no description available]medium10dicarboxylic acidbacterial xenobiotic metabolite
acetyl coenzyme a[no description available]medium10acyl-CoAacyl donor;
coenzyme;
effector;
fundamental metabolite
aluminum[no description available]medium10boron group element atom;
elemental aluminium;
metal atom
xanthenes[no description available]medium10xanthene
alpha-ketoglutaric acid[no description available]low00oxo dicarboxylic acidfundamental metabolite
beta-alanine[no description available]low00amino acid zwitterion;
beta-amino acid		agonist;
fundamental metabolite;
human metabolite;
inhibitor;
neurotransmitter
betaine hydrochloride[no description available]low00quaternary ammonium ionfundamental metabolite
citric acid, anhydrous[no description available]low00tricarboxylic acidantimicrobial agent;
chelator;
food acidity regulator;
fundamental metabolite
cysteine[no description available]low00alpha-amino acid;
amino acid zwitterion;
polar amino acid;
sulfur-containing amino acid		fundamental metabolite
alanine[no description available]low00alpha-amino acid;
amino acid zwitterion		fundamental metabolite
3-phosphoglycerate[no description available]low00monophosphoglyceric acid;
tetronic acid derivative		algal metabolite;
fundamental metabolite
glyceraldehyde[no description available]low00aldotriosefundamental metabolite
glyceric acid[no description available]low00trionic acidfundamental metabolite
glycolaldehyde[no description available]low00glycolaldehydesfundamental metabolite;
human metabolite
thioctic acid[no description available]low00dithiolanes;
heterocyclic fatty acid;
thia fatty acid		fundamental metabolite;
geroprotector
putrescine[no description available]low00alkane-alpha,omega-diamineantioxidant;
fundamental metabolite
spermidine[no description available]low00polyazaalkane;
triamine		autophagy inducer;
fundamental metabolite;
geroprotector
spermine[no description available]low00polyazaalkane;
tetramine		antioxidant;
fundamental metabolite;
immunosuppressive agent
succinic acid[no description available]low00alpha,omega-dicarboxylic acid;
C4-dicarboxylic acid		anti-ulcer drug;
fundamental metabolite;
micronutrient;
nutraceutical;
radiation protective agent
isocitric acid[no description available]low00secondary alcohol;
tricarboxylic acid		fundamental metabolite
nadp[no description available]low00NADPfundamental metabolite
uridine[no description available]low00uridinesdrug metabolite;
fundamental metabolite;
human metabolite
uridine diphosphate glucose[no description available]low00UDP-D-glucosefundamental metabolite
thymidine monophosphate[no description available]low00thymidine 5'-monophosphatefundamental metabolite
2'-deoxy-5'-adenosine monophosphate[no description available]low002'-deoxyadenosine 5'-phosphate;
purine 2'-deoxyribonucleoside 5'-monophosphate		fundamental metabolite
pseudouridine[no description available]low00pseudouridinesfundamental metabolite
uridine diphosphate xylose[no description available]low00UDP-sugarfundamental metabolite
serum p-component[no description available]low00citrate anion;
tricarboxylic acid trianion		fundamental metabolite
6-phosphogluconic acid[no description available]low00gluconic acid phosphatefundamental metabolite
homocysteine[no description available]low00amino acid zwitterion;
homocysteine;
serine family amino acid		fundamental metabolite;
mouse metabolite
biotin[no description available]low00biotins;
vitamin B7		coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite
s-adenosylhomocysteine[no description available]low00adenosines;
amino acid zwitterion;
homocysteine derivative;
homocysteines;
organic sulfide		cofactor;
EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor;
EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor;
epitope;
fundamental metabolite
aconitic acid[no description available]low00aconitic acidfundamental metabolite
riboflavin[no description available]low00flavin;
vitamin B2		anti-inflammatory agent;
antioxidant;
cofactor;
Escherichia coli metabolite;
food colouring;
fundamental metabolite;
human urinary metabolite;
mouse metabolite;
photosensitizing agent;
plant metabolite
mannose 1-phosphate[no description available]low00mannose phosphatefundamental metabolite;
human metabolite
adenosine triphosphate[no description available]low00nucleoside 5'-triphoshate(4-)cofactor;
fundamental metabolite;
human metabolite
adenosine diphosphate[no description available]low00nucleoside 5'-diphosphate(3-)fundamental metabolite;
human metabolite
adenosine monophosphate[no description available]low00nucleoside 5'-monophosphate(2-)cofactor;
fundamental metabolite;
human metabolite
guanosine[no description available]low00guanosines;
purines D-ribonucleoside		fundamental metabolite
hypoxanthine[no description available]low00nucleobase analogue;
oxopurine;
purine nucleobase		fundamental metabolite
inosine diphosphate[no description available]low00inosine phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite
4-(dimethylamino)benzaldehyde[no description available]low00benzaldehydes;
substituted aniline;
tertiary amino compound		chromogenic compound
5-bromo-4-chloroindoxyl acetate[no description available]low00acetate ester;
bromoindole;
chloroindole		chromogenic compound
5-bromo-4-chloro-3-indolyl beta-galactoside[no description available]low00beta-D-galactoside;
D-aldohexose derivative;
indolyl carbohydrate;
organobromine compound;
organochlorine compound		chromogenic compound
5-bromo-4-chloro-3-indoxyl phosphate[no description available]low00aryl phosphate;
indoles;
organobromine compound;
organochlorine compound		chromogenic compound
benzoyltyrosine ethyl ester[no description available]low00benzamides;
ethyl ester;
L-tyrosine derivative;
phenols		chromogenic compound
4-nitrophenyl-alpha-l-fucoside[no description available]low00alpha-L-fucoside;
C-nitro compound		chromogenic compound
4-nitrophenylglucuronide[no description available]low00beta-D-glucosiduronic acid;
C-nitro compound		chromogenic compound
beta-naphthyl phosphate[no description available]low00aryl phosphatechromogenic compound
6-bromo-2-naphthyl-beta-galactopyranoside[no description available]low00beta-D-galactoside;
organobromine compound		chromogenic compound
4-methylumbelliferyl butyrate[no description available]low00butyrate ester;
coumarins		chromogenic compound
4-nitrophenyl beta-d-xyloside[no description available]low00C-nitro compound;
xyloside		chromogenic compound
4-methylumbelliferyl glucuronide[no description available]low00beta-D-glucosiduronic acid;
coumarins;
monosaccharide derivative		antineoplastic agent;
chromogenic compound;
hyaluronan synthesis inhibitor
4-nitrophenyl beta-d-glucoside[no description available]low00beta-D-glucoside;
C-nitro compound		chromogenic compound
4-nitrophenyl alpha-glucoside[no description available]low00alpha-D-glucoside;
C-nitro compound;
monosaccharide derivative		chromogenic compound
4-methylumbelliferyl-galactopyranoside[no description available]low00beta-D-galactoside;
coumarins;
monosaccharide derivative		chromogenic compound
nitrophenylgalactosides[no description available]low00beta-D-galactoside;
C-nitro compound		chromogenic compound
4-nitrophenyl-2-acetamido-2-deoxy-beta-d-glucopyranoside[no description available]low00C-nitro compound;
N-acetyl-beta-D-glucosaminide		chromogenic compound
leucine-beta-naphthylamide[no description available]low00amino acid amide;
L-leucine derivative;
N-(2-naphthyl)carboxamide		chromogenic compound
phenylalanine-beta-naphthylamide[no description available]low00amino acid amide;
L-phenylalanine derivative;
N-(2-naphthyl)carboxamide		chromogenic compound
arginine beta-naphthylamide[no description available]low00amino acid amide;
L-arginine derivative;
N-(2-naphthyl)carboxamide		chromogenic compound
glycylphenylalanine 2-naphthylamide[no description available]low00dipeptide;
N-(2-naphthyl)carboxamide		chromogenic compound
gamma-glutamyl-2-naphthylamide[no description available]low00amino acid amide;
L-glutamic acid derivative;
N-(2-naphthyl)carboxamide		chromogenic compound
4-nitrocatechol sulfate[no description available]low004-nitrophenols;
aryl sulfate		chromogenic compound
L-histidine 2-naphthylamide[no description available]low00amino acid amide;
L-histidine derivative;
N-(2-naphthyl)carboxamide		chromogenic compound
4-methylumbelliferyl glucoside[no description available]low00beta-D-glucoside;
coumarins;
monosaccharide derivative		chromogenic compound
aspartic acid beta-naphthylamide[no description available]low00amino acid amide;
L-aspartic acid derivative;
N-(2-naphthyl)carboxamide		chromogenic compound
alpha-ketoglutaramate[no description available]low002-oxo monocarboxylic acid
oxaluric acid[no description available]low002-oxo monocarboxylic acid;
ureas		Escherichia coli metabolite
alpha-keto-delta-guanidinovaleric acid[no description available]low002-oxo monocarboxylic acid;
zwitterion		human metabolite;
mouse metabolite
3-fluoropyruvate[no description available]low002-oxo monocarboxylic acid;
organofluorine compound
bromopyruvate[no description available]low002-oxo monocarboxylic acid;
organobromine compound;
oxo carboxylic acid		alkylating agent;
antineoplastic agent
vanillactic acid[no description available]low002-oxo monocarboxylic acid
2-ketoarginine[no description available]low002-oxo monocarboxylic acid;
zwitterion		human metabolite;
mouse metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
47,XX,+210low10
47,XY,+210low10
Abnormalities, Congenital0low10
Acute Confusional Senile Dementia0low10
Acute Kidney Failure0low10
Acute Kidney Injury0low10
Acute Kidney Insufficiency0low10
Acute Liver Injury, Drug-Induced0low10
Acute Renal Failure0low10
Acute Renal Injury0low10
Acute Renal Insufficiency0low10
Addison Disease0low10
Addison's Disease0low10
Adenoma, beta-Cell0low10
African Sleeping Sickness0low10
African Trypanosomiasis0low10
Alcaptonuria0low10
Alkaptonuria0low10
Alloxan Diabetes0low10
Alzheimer Dementia0low10
Alzheimer Disease0low10
Alzheimer Disease, Early Onset0low10
Alzheimer Disease, Late Onset0low10
Alzheimer Sclerosis0low10
Alzheimer Syndrome0low10
Alzheimer Type Senile Dementia0low10
Alzheimer-Type Dementia (ATD)0low10
Alzheimer's Disease0low10
Alzheimer's Disease, Focal Onset0low10
Alzheimer's Diseases0low10
Amentia0low10
Amino Acid Metabolism Disorders, Inborn0low50
Amino Acid Metabolism, Inborn Error0low50
Amino Acid Metabolism, Inborn Errors0low50
Amino Acid Metabolism, Inherited Disorders0low50
Amino Acidopathies, Congenital0low50
Amino Acidopathies, Inborn0low50
Aminoaciduria, Renal0low30
Anemia0low20
Anemia, Aplastic0low10
Anemia, Hypochromic0low10
Anemia, Hypoplastic0low10
Anemia, Splenic0low10
Aplastic Anaemia0low10
Aplastic Anemia0low10
Arthritis, Rheumatoid0low10
Ascorbic Acid Deficiency0low10
Behavior Disorders0low10
Benign Neoplasms0low20
beta-Cell Tumor0low10
BH4 Deficiency0low560
Birth Defects0low10
Blood Diseases0low10
Bovine Diseases0low10
Cancer0low20
Cancer of Liver0low10
Cancer of Nasopharynx0low10
Cancer of Pancreas0low10
Cancer of the Liver0low10
Cancer of the Nasopharynx0low10
Cancer of the Pancreas0low10
Cancer, Hepatocellular0low10
Canine Diseases0low10
Carcinoma0low10
Carcinoma, Anaplastic0low10
Carcinoma, Epidermoid0low10
Carcinoma, Hepatocellular0low10
Carcinoma, Planocellular0low10
Carcinoma, Spindle-Cell0low10
Carcinoma, Squamous0low10
Carcinoma, Squamous Cell0low10
Carcinoma, Undifferentiated0low10
Carcinomatosis0low10
Cardiovascular Diseases0low10
Cattle Diseases0low10
Cellulitis0low10
Chemical and Drug Induced Liver Injury0low10
Chemically-Induced Liver Toxicity0low10
Chlorosis0low10
Chromosome Inversion0low10
Chronic Kidney Disease-Mineral and Bone Disorder0low20
Cirrhosis, Liver0low40
CKD-MBD0low20
Collagen Diseases0low20
Complications, Pregnancy0low10
Congenital Abnormalities0low10
Congenital Amino Acidopathies0low50
Congenital Defects0low10
Congenital Dysplasia Of The Hip0low10
Congenital Hip Dislocation0low10
Congenital Hip Displacement0low10
Congenital Hip Dysplasia0low10
Defects, Congenital0low10
Deficiency Disease, Dihydropteridine Reductase0low560
Deficiency Disease, Phenylalanine Hydroxylase0low560
Deficiency Disease, Phenylalanine Hydroxylase, Severe0low560
Deficiency Diseases0low10
Deficiency, Ascorbic Acid0low10
Deficiency, Mental0low90
Deficiency, Riboflavin0low10
Deficiency, Thiamine0low10
Deficiency, Vitamin C0low10
Deformities0low10
Dementia0low10
Dementia, Alzheimer Type0low10
Dementia, Presenile0low10
Dementia, Primary Senile Degenerative0low10
Dementia, Senile0low10
DHPR Deficiency0low560
Diabetes Mellitus0low20
Diabetes Mellitus, Experimental0low10
Diagnosis, Psychiatric0low10
Dihydropteridine Reductase Deficiency0low560
Dihydropteridine Reductase Deficiency Disease0low560
Disability, Intellectual0low90
Disease Models, Animal0low30
Diseases of Endocrine System0low10
Diseases, Metabolic0low40
Dislocation Of Hip, Congenital0low10
Dislocation, Congenital Hip0low10
Displacement, Congenital Hip0low10
Dog Diseases0low10
Down Syndrome0low10
Down Syndrome, Partial Trisomy 210low10
Down's Syndrome0low10
Drug-Induced Acute Liver Injury0low10
Drug-Induced Liver Disease0low10
Drug-Induced Liver Injury0low10
Dysplasia, Congenital Hip0low10
Early Onset Alzheimer Disease0low10
Elevated Cholesterol0low10
Endocrine Diseases0low10
Endocrine System Diseases0low10
Enlarged Liver0low10
Epithelial Neoplasms, Malignant0low10
Epithelial Tumors, Malignant0low10
Epithelioma0low10
Experimental Diabetes Mellitus0low10
Familial Alzheimer Disease (FAD)0low10
Familial Dementia0low10
Fasting Hypoglycemia0low10
Fetal Anomalies0low10
Fetal Malformations0low10
Fibrosis, Liver0low40
Focal Onset Alzheimer's Disease0low10
Folling Disease0low560
Folling's Disease0low560
Genetic Diseases0low10
Genetic Diseases, Inborn0low10
Genetic Disorders0low10
Hematologic Diseases0low10
Hematological Diseases0low10
Hepatic Cancer0low10
Hepatic Cirrhosis0low40
Hepatic Neoplasms0low10
Hepatitis0low20
Hepatitis A0low10
Hepatitis, Drug-Induced0low10
Hepatitis, Infectious0low10
Hepatitis, Toxic0low10
Hepatocellular Cancer0low10
Hepatocellular Carcinoma0low10
Hepatoma0low10
Hepatomegaly0low10
Hereditary Disease0low10
Hereditary Diseases0low10
High Cholesterol Levels0low10
Hip Dislocation0low10
Hip Dislocation, Congenital0low10
Hip Displacement0low10
Hip Displacement, Congenital0low10
Hip Dysplasia0low10
Hip Dysplasia, Congenital0low10
Hip Dysplasia, Congenital, Nonsyndromic0low10
Hip, Dislocation Of, Congenital0low10
Homogentisic Acid Oxidase Deficiency0low10
Homogentisic Acidura0low10
HPABH4C0low560
Hyperactivity, Motor0low10
Hypercholesteremia0low10
Hypercholesterolemia0low10
Hyperkinesia0low10
Hyperkinesia, Generalized0low10
Hyperkinesis0low10
Hyperkinetic Movements0low10
Hyperphenylalaninaemia0low560
Hyperphenylalaninemia Caused by a Defect in Biopterin Metabolism0low560
Hyperphenylalaninemia, BH4-Deficient, C0low560
Hyperphenylalaninemia, Non-Phenylketonuric0low560
Hyperphenylalaninemia, Tetrahydrobiopterin-Deficient, Due To DHPR Deficiency0low560
Hypersplenism0low10
Hypoglycemia0low10
Hypoparathyroidism0low10
Idiocy0low90
Idiopathic Hypoparathyroidism0low10
Inborn Errors of Metabolism0low10
Inborn Errors, Amino Acid Metabolism0low50
Inborn Genetic Diseases0low10
Infant, Newborn, Diseases0low10
Infectious Hepatitis0low10
Inflammation0low10
Inherited Errors of Amino Acid Metabolism0low50
Innate Inflammatory Response0low10
Insulinoma0low10
Insuloma0low10
Intellectual Development Disorder0low90
Intellectual Disability0low90
Inversion, Chromosomal0low10
Inversion, Chromosome0low10
Kidney Diseases0low20
Kidney Failure0low10
Kidney Failure, Acute0low10
Kidney Insufficiency0low10
Kidney Insufficiency, Acute0low10
Kidney Tubular Transport, Inborn Error0low10
Kidney Tubular Transport, Inborn Errors0low10
Koch's Disease0low10
Kochs Disease0low10
Kwashiorkor0low20
Late Onset Alzheimer Disease0low10
Leucocythaemia0low10
Leucocythemia0low10
Leukemia0low10
Liver Cancer0low10
Liver Cancer, Adult0low10
Liver Cell Carcinoma0low10
Liver Cell Carcinoma, Adult0low10
Liver Cirrhosis0low40
Liver Diseases0low30
Liver Dysfunction0low30
Liver Fibrosis0low40
Liver Injury, Drug-Induced0low10
Liver Injury, Drug-Induced, Acute0low10
Liver Neoplasms0low10
Malignancy0low20
Malignant Epithelial Neoplasms0low10
Malignant Melanoma0low10
Malignant Neoplasms0low20
Melanoma0low10
Mental Deficiency0low90
Mental Disorders0low10
Mental Disorders, Severe0low10
Mental Illness0low10
Mental Retardation0low90
Mental Retardation, Psychosocial0low90
Metabolic Diseases0low40
Metabolism Errors, Inborn0low10
Metabolism, Inborn Errors0low10
Metastase0low10
Metastases, Neoplasm0low10
Metastasis0low10
Metastasis, Neoplasm0low10
Mongolism0low10
Mycobacterium tuberculosis Infection0low10
Nagana0low10
Nasopharyngeal Cancer0low10
Nasopharyngeal Carcinoma0low10
Nasopharyngeal Neoplasms0low10
Nasopharynx Cancer0low10
Nasopharynx Neoplasms0low10
Necrosis0low10
Neonatal Diseases0low10
Neoplasia0low20
Neoplasm0low20
Neoplasm Metastases0low10
Neoplasm Metastasis0low10
Neoplasms0low20
Neoplasms, Benign0low20
Neoplasms, Hepatic0low10
Neoplasms, Liver0low10
Neoplasms, Malignant Epithelial0low10
Neoplasms, Nasopharyngeal0low10
Neoplasms, Pancreatic0low10
Nephrosis0low10
Nerve Degeneration0low10
Neuroblastoma0low10
Neuron Degeneration0low10
Non-Phenylketonuric Hyperphenylalaninemia0low560
Obesity0low10
Oligophrenia Phenylpyruvica0low560
Osteodystrophy, Renal0low20
Ovine Diseases0low10
PAH Deficiency0low560
Pancreas Cancer0low10
Pancreas Neoplasms0low10
Pancreatic Cancer0low10
Pancreatic Neoplasms0low10
Partial Trisomy 21 Down Syndrome0low10
Phenylalanine Hydroxylase Deficiency0low560
Phenylalanine Hydroxylase Deficiency Disease0low560
Phenylalanine Hydroxylase Deficiency Disease, Severe0low560
Phenylketonuria0low560
Phenylketonuria I0low560
Phenylketonuria II0low560
Phenylketonuria Type 20low560
Phenylketonuria, Atypical0low560
Phenylketonuria, Classical0low560
Phenylketonurias0low560
Phlegmon0low10
PKU, Atypical0low560
Postabsorptive Hypoglycemia0low10
Postprandial Hypoglycemia0low10
Pregnancy0low20
Pregnancy Complications0low10
Presenile Alzheimer Dementia0low10
Primary Adrenal Insufficiency0low10
Primary Adrenocortical Insufficiency0low10
Primary Hypoadrenalism0low10
Primary Senile Degenerative Dementia0low10
Psychiatric Diagnosis0low10
Psychiatric Diseases0low10
Psychiatric Disorders0low10
Psychiatric Illness0low10
Psychoses0low10
Psychosis0low10
Psychosis, Brief Reactive0low10
Psychotic Disorders0low10
Pyloric Stenosis0low10
QDPR Deficiency0low560
Quinoid Dihydropteridine Reductase Deficiency0low560
Rachitis0low30
Reactive Hypoglycemia0low10
Renal Aminoacidurias0low30
Renal Failure0low10
Renal Failure, Acute0low10
Renal Insufficiency0low10
Renal Insufficiency, Acute0low10
Renal Osteodystrophy0low20
Renal Rickets0low20
Renal Tubular Transport Errors0low10
Renal Tubular Transport, Inborn Error0low10
Renal Tubular Transport, Inborn Errors0low10
Retardation, Mental0low90
Rheumatoid Arthritis0low10
Riboflavin Deficiency0low10
Rickets0low30
Rickets, Renal0low20
Schizoaffective Disorder0low10
Schizophreniform Disorders0low10
Scleroderma, Systemic0low10
Sclerosis, Systemic0low10
Senile Dementia, Acute Confusional0low10
Senile Dementia, Alzheimer Type0low10
Senile Paranoid Dementia0low10
Sheep Diseases0low10
Single-Gene Defects0low10
Squamous Cell Carcinoma0low10
Starvation0low10
Stenosis, Pyloric0low10
Streptozocin Diabetes0low10
Streptozotocin Diabetes0low10
Systemic Scleroderma0low10
Systemic Sclerosis0low10
Tetrahydrobiopterin Deficiency0low560
Thesaurismosis0low40
Thiamine Deficiency0low10
Thyroid Diseases0low10
Toxic Hepatitis0low10
Trisomy 210low10
Trisomy 21, Meiotic Nondisjunction0low10
Trisomy 21, Mitotic Nondisjunction0low10
Trisomy G0low10
Trypanosomiasis, African0low10
Tuberculosis0low10
Tumors0low20
Vitamin C Deficiency0low10