nitroxyl has been researched along with Neuroblastoma in 6 studies
nitroxyl: hydroxamic acid oxidized to nitroxyl free radical
nitroxyl : A nitrogen oxoacid consisting of an oxygen atom double-bonded to an NH group.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The tissues (cancer and 'normal') of cancer-bearing mammals were characterised by a long-lived MRI signal (τ1/2>14 min), indicating a high oxidative activity." | 1.39 | Tissue redox activity as a sensing platform for imaging of cancer based on nitroxide redox cycle. ( Aoki, I; Bakalova, R; Gadjeva, V; Nikolova, B; Saga, T; Zhelev, Z, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Pieńkowska, N | 1 |
| Fahnestock, M | 1 |
| Mahadeo, C | 1 |
| Zaborniak, I | 1 |
| Chmielarz, P | 1 |
| Bartosz, G | 1 |
| Sadowska-Bartosz, I | 1 |
| Bakalova, R | 3 |
| Zhelev, Z | 3 |
| Aoki, I | 3 |
| Saga, T | 3 |
| Gadjeva, V | 2 |
| Chonpathompikunlert, P | 1 |
| Yoshitomi, T | 1 |
| Han, J | 1 |
| Toh, K | 1 |
| Isoda, H | 1 |
| Nagasaki, Y | 1 |
| Nikolova, B | 1 |
| Arroyo, CM | 1 |
| Forray, C | 1 |
6 other studies available for nitroxyl and Neuroblastoma
| Article | Year |
|---|---|
Induction of Oxidative Stress in SH-SY5Y Cells by Overexpression of hTau40 and Its Mitigation by Redox-Active Nanoparticles.
Topics: Cell Line, Tumor; Humans; Nanoparticles; Neuroblastoma; Oxidation-Reduction; Oxidative Stress; React | 2022 |
Tissue redox activity as a hallmark of carcinogenesis: from early to terminal stages of cancer.
Topics: Animals; Antioxidants; Brain Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Contrast | 2013 |
Cell-penetrating nitroxides as molecular sensors for imaging of cancer in vivo, based on tissue redox activity.
Topics: Animals; Brain Neoplasms; Cell Membrane Permeability; Contrast Media; Cyclic N-Oxides; Electron Spin | 2012 |
Chemical nanotherapy: nitroxyl radical-containing nanoparticle protects neuroblastoma SH-SY5Y cells from Abeta-induced oxidative stress.
Topics: Amyloid beta-Peptides; Apoptosis; Cell Line, Tumor; Free Radicals; Humans; Lipid Peroxidation; Nanop | 2011 |
Tissue redox activity as a sensing platform for imaging of cancer based on nitroxide redox cycle.
Topics: Animals; Brain; Cell Line, Tumor; Colonic Neoplasms; Cyclic N-Oxides; Electron Spin Resonance Spectr | 2013 |
Activation of cyclic GMP formation in mouse neuroblastoma cells by a labile nitroxyl radical. An electron paramagnetic resonance/spin trapping study.
Topics: Animals; Arginine; Benzenesulfonates; Cyclic AMP; Electron Spin Resonance Spectroscopy; Enzyme Activ | 1991 |