aminolevulinic acid has been researched along with Neuroblastoma in 6 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-Aminolevulinic acid (ALA) has shown promising in photodynamic detection and therapy of brain tumor." | 5.32 | Protoporphyrin IX production and its photodynamic effects on glioma cells, neuroblastoma cells and normal cerebellar granule cells in vitro with 5-aminolevulinic acid and its hexylester. ( Chen, JY; Peng, Q; Ren, QG; Wu, SM; Zhou, MO, 2003) |
| "The purpose of this study was to test the susceptibility of human hepatoblastoma and neuroblastoma cells to photodynamic diagnostics (PDD) and photodynamic therapy (PDT) using 5-aminolevulinic acid (5-ALA) as a photosensitizer." | 3.74 | In vitro and in vivo evaluation of photodynamic techniques for the experimental treatment of human hepatoblastoma and neuroblastoma: preliminary results. ( Bergmann, F; Johansson, A; Metzger, R; Rolle, U; Stepp, H; Till, H, 2008) |
| "5-Aminolevulinic acid (ALA) has shown promising in photodynamic detection and therapy of brain tumor." | 1.32 | Protoporphyrin IX production and its photodynamic effects on glioma cells, neuroblastoma cells and normal cerebellar granule cells in vitro with 5-aminolevulinic acid and its hexylester. ( Chen, JY; Peng, Q; Ren, QG; Wu, SM; Zhou, MO, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Watanabe, T | 1 |
| Nishio, Y | 1 |
| Yamamoto, Y | 1 |
| Shimizu, T | 1 |
| Li, XK | 1 |
| Okita, H | 1 |
| Kuroda, T | 1 |
| Bergmann, F | 1 |
| Stepp, H | 1 |
| Metzger, R | 1 |
| Rolle, U | 1 |
| Johansson, A | 1 |
| Till, H | 1 |
| Wu, SM | 1 |
| Ren, QG | 1 |
| Zhou, MO | 1 |
| Peng, Q | 1 |
| Chen, JY | 1 |
| Grünberg-Etkovitz, N | 1 |
| Greenbaum, L | 1 |
| Grinblat, B | 1 |
| Malik, Z | 1 |
| Helson, L | 1 |
| Braverman, S | 1 |
| Mangiardi, J | 1 |
| Takase, N | 1 |
| Inden, M | 1 |
| Sekine, SI | 1 |
| Ishii, Y | 1 |
| Yonemitsu, H | 1 |
| Iwashita, W | 1 |
| Kurita, H | 1 |
| Taketani, Y | 1 |
| Hozumi, I | 1 |
6 other studies available for aminolevulinic acid and Neuroblastoma
| Article | Year |
|---|---|
Photodynamic therapy with 5-aminolevulinic acid: A new diagnostic, therapeutic, and surgical aid for neuroblastoma.
Topics: Aminolevulinic Acid; Cell Line, Tumor; Humans; Neuroblastoma; Photochemotherapy; Photosensitizing Ag | 2022 |
In vitro and in vivo evaluation of photodynamic techniques for the experimental treatment of human hepatoblastoma and neuroblastoma: preliminary results.
Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Cell Survival; Hepatoblastoma; Humans; Models, Anima | 2008 |
Protoporphyrin IX production and its photodynamic effects on glioma cells, neuroblastoma cells and normal cerebellar granule cells in vitro with 5-aminolevulinic acid and its hexylester.
Topics: Aminolevulinic Acid; Animals; Brain Neoplasms; Cell Line; Cerebellum; Glioma; Humans; Neuroblastoma; | 2003 |
Proteasomal degradation regulates expression of porphobilinogen deaminase (PBGD) mutants of acute intermittent porphyria.
Topics: Aminolevulinic Acid; Cell Line, Tumor; Cell Nucleus; Cysteine Proteinase Inhibitors; Cytoplasm; Gene | 2006 |
delta-Aminolevulinic acid effects on neuronal and glial tumor cell lines.
Topics: Aminolevulinic Acid; Cell Survival; Deferoxamine; Glioblastoma; Hemin; Humans; Nervous System Diseas | 1993 |
Neuroprotective effect of 5-aminolevulinic acid against low inorganic phosphate in neuroblastoma SH-SY5Y cells.
Topics: Aminolevulinic Acid; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Heme O | 2017 |