4-cresol has been researched along with Neuroblastoma in 1 studies
4-cresol: RN given refers to parent cpd
p-cresol : A cresol that consists of toluene substituted by a hydroxy group at position 4. It is a metabolite of aromatic amino acid metabolism produced by intestinal microflora in humans and animals.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response curves confirmed that Al uptake and cell toxicity were proportional to p-cresol from 1." | 1.30 | P-Cresol, a uremic compound, enhances the uptake of aluminum in hepatocytes. ( Abreo, K; De Smet, R; Gautreaux, S; Ringoir, S; Sella, M; Vanholder, R; Vogeleere, P, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abreo, K | 1 |
| Sella, M | 1 |
| Gautreaux, S | 1 |
| De Smet, R | 1 |
| Vogeleere, P | 1 |
| Ringoir, S | 1 |
| Vanholder, R | 1 |
1 other study available for 4-cresol and Neuroblastoma
| Article | Year |
|---|---|
P-Cresol, a uremic compound, enhances the uptake of aluminum in hepatocytes.
Topics: Aluminum; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Cresols; Drug Synergism; L | 1997 |